Artificial ultraviolet whole-body radiation does not modify serum lipoprotein, plasma fibrinogen, plasminogen or antithrombin III concentrations in post-myocardial infarction patients.

Abstract:

:The relationship of ischaemic heart disease (IHD) to seasonal and latitude variation has prompted speculation that exposure to the ultraviolet component of solar radiation may reduce IHD risk. This hypothesis was partially tested by exposing 14 post-myocardial infarction patients to a 6 week course of artificial whole-body ultraviolet radiation (UVR). Serum lipoprotein and plasma coagulation factor concentrations were measured before and after the course of UVR. Results were compared with similar measurements from a placebo-controlled group of 13 post-myocardial patients. Despite a more than two-fold rise in mean serum 25-OHD, serum lipoprotein and plasma fibrinogen, antithrombin III and plasminogen concentrations did not change significantly in the UVR group. Significant but minor change in prothrombin time and thrombin time in the placebo group appear unlikely to be of biological significance. Seasonal and latitude variation in these IHD risk factors appear unrelated to corresponding variation in solar UVR exposure.

journal_name

Atherosclerosis

journal_title

Atherosclerosis

authors

Clark P,Cockburn F,Cowan RA,Czapla K,Dunnigan MG,Farish E,Hughes E

doi

10.1016/0021-9150(94)90142-2

subject

Has Abstract

pub_date

1994-05-01 00:00:00

pages

65-9

issue

1

eissn

0021-9150

issn

1879-1484

pii

0021-9150(94)90142-2

journal_volume

107

pub_type

临床试验,杂志文章
  • Primary culture of endothelial cells from atherosclerotic human aorta. Part 1. Identification, morphological and ultrastructural characteristics of two endothelial cell subpopulations.

    abstract::Endothelial cells (EC) were harvested by 0.1% collagenase treatment for adult human thoracic aortas obtained 1-3 h after sudden death. At least 35-70% of EC were removed from the intimal surface of aorta, 90-95% of them being viable. Plating efficiency was 70-80%. Monolayer formation was achieved at a seeding density ...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/0021-9150(86)90027-4

    authors: Antonov AS,Nikolaeva MA,Klueva TS,Romanov YuA,Babaev VR,Bystrevskaya VB,Perov NA,Repin VS,Smirnov VN

    更新日期:1986-01-01 00:00:00

  • Single nucleotide polymorphism on chromosome 9p21 and endothelial progenitor cells in a general population cohort.

    abstract:OBJECTIVE:Recent studies have revealed that sequence variation on chromosome 9p21 is a major genetic determinant for coronary heart disease and stroke, however, the underlying mechanism remains unknown. This genomic region contains the gene encoding cyclin-dependent kinase 2A, a regulator of proliferation and different...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2009.08.006

    authors: Ye S,Willeit J,Xiao Q,Motterle A,Laxton RC,Oberhollenzer F,Kiechl S,Xu Q

    更新日期:2010-02-01 00:00:00

  • Room for depressed and exhausted mood as a risk predictor for all-cause and cardiovascular mortality beyond the contribution of the classical somatic risk factors in men.

    abstract:BACKGROUND AND AIMS:Depressed mood and exhaustion (DEEX) have gained attention as a risk predictor for cardiovascular disease (CVD). Studies to estimate its ranking in prediction models are sparse. METHODS:The study included 3428 men aged 45-74 years who participated in one of three population-based MONICA/KORA Augsbu...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2016.12.003

    authors: Ladwig KH,Baumert J,Marten-Mittag B,Lukaschek K,Johar H,Fang X,Ronel J,Meisinger C,Peters A,KORA Investigators.

    更新日期:2017-02-01 00:00:00

  • Dialysis of isolated low density lipoprotein induces a loss of lipophilic antioxidants and increases the susceptibility to oxidation in vitro.

    abstract::We determined the effects of different dialysis conditions on the antioxidant content, duration of the lag phase and oxidation rate of LDL. Dialysis for 22 h resulted in a 56%--66% reduction in the concentrations of beta-carotene, lycopene and alpha-tocopherol. The lag phase of copper-induced oxidation of freshly isol...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/0021-9150(95)05555-b

    authors: Scheek LM,Wiseman SA,Tijburg LB,van Tol A

    更新日期:1995-09-01 00:00:00

  • Metabolic products of the intestinal microbiome and extremes of atherosclerosis.

    abstract:BACKGROUND AND AIMS:There is increasing awareness that the intestinal microbiome plays an important role in human health. We investigated its role in the burden of carotid atherosclerosis, measured by ultrasound as total plaque area. METHODS:Multiple regression with traditional risk factors was used to identify three ...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2018.04.015

    authors: Bogiatzi C,Gloor G,Allen-Vercoe E,Reid G,Wong RG,Urquhart BL,Dinculescu V,Ruetz KN,Velenosi TJ,Pignanelli M,Spence JD

    更新日期:2018-06-01 00:00:00

  • Serum lipids, lipoprotein(a) and apo(a) isoforms in patients with established coronary artery disease and their relation to disease and prognosis after coronary by-pass surgery.

    abstract::Consecutive patients (n=964) undergoing coronary angiography were studied and compared with a random population sample regarding serum lipids and lipoproteins with focus on lipoprotein(a) (Lp[a]) levels and apo(a) isoforms. The patients were also followed for 5 years after the angiography, and the prognostic value of ...

    journal_title:Atherosclerosis

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0021-9150(97)00247-5

    authors: Lindén T,Taddei-Peters W,Wilhelmsen L,Herlitz J,Karlsson T,Ullström C,Wiklund O

    更新日期:1998-03-01 00:00:00

  • ApoB/apoA-I ratio is related to femoral artery plaques in 64-year-old women also in cases with low LDL cholesterol.

    abstract:INTRODUCTION:The apolipoproteinB (apoB)/apolipoproteinA-I (apoA-I) ratio mirrors the number of pro-atherogenic and anti-atherogenic lipoprotein particles. This ratio may carry more information on risk for atherosclerosis than LDL in cohorts with impaired glucose tolerance. The aim was to examine the association between...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2007.01.017

    authors: Schmidt C,Fagerberg B

    更新日期:2008-02-01 00:00:00

  • Resistance training changes LDL metabolism in normolipidemic subjects: a study with a nanoemulsion mimetic of LDL.

    abstract:OBJECTIVE:To evaluate the effects of resistance training (RT) on the metabolism of an LDL-like nanoemulsion and on lipid transfer to HDL, an important step of HDL metabolism. METHODS:LDL-like nanoemulsion plasma kinetics was studied in 15 healthy men under regular RT for 1-4 years (age = 25 ± 5 years, VO(2)peak = 50 ±...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2011.08.014

    authors: da Silva JL,Vinagre CG,Morikawa AT,Alves MJ,Mesquita CH,Maranhão RC

    更新日期:2011-12-01 00:00:00

  • Antiatherogenic effect of angiotensin converting enzyme inhibitor (benazepril) and angiotensin II receptor antagonist (valsartan) in the cholesterol-fed rabbits.

    abstract::The purpose of this study was to determine whether an angiotensin converting enzyme (ACE) inhibitor, benazepril, and an angiotensin receptor antagonist, valsartan, would decrease atherosclerotic severity in cholesterol-fed rabbits. Male rabbits were fed either: (a) normal rabbit chow; (b) 2% cholesterol diet; (c) 2% c...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/s0021-9150(98)00309-8

    authors: Li J,Hirose N,Kawamura M,Arai Y

    更新日期:1999-04-01 00:00:00

  • Fibroblast growth factor 23, left ventricular mass, and left ventricular hypertrophy in community-dwelling older adults.

    abstract:OBJECTIVES:In chronic kidney disease (CKD), high FGF23 concentrations are associated with left ventricular hypertrophy (LVH), cardiovascular events, and death. The associations of FGF23 with left ventricular mass (LVM) and LVH in the general population and the influence of CKD remains uncertain. METHODS:C-terminal pla...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2013.09.002

    authors: Jovanovich A,Ix JH,Gottdiener J,McFann K,Katz R,Kestenbaum B,de Boer IH,Sarnak M,Shlipak MG,Mukamal KJ,Siscovick D,Chonchol M

    更新日期:2013-11-01 00:00:00

  • LIPC variants in the promoter and intron 1 modify HDL-C levels in a sex-specific fashion.

    abstract::We previously reported linkage for plasma levels of high-density lipoprotein cholesterol (HDL-C) on 15q21 in Caucasian families from the National Heart, Lung, and Blood Institute Family Heart Study (NHLBI FHS). Hepatic lipase gene (LIPC), which has a major role in lipoprotein metabolism, resides within the linkage reg...

    journal_title:Atherosclerosis

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.atherosclerosis.2008.09.007

    authors: Feitosa MF,Myers RH,Pankow JS,Province MA,Borecki IB

    更新日期:2009-05-01 00:00:00

  • Modulation of arterial thrombosis tendency in rats by vitamin K and its side chains.

    abstract::Vitamin K is involved in the biosynthesis of a number of blood coagulation factors and bone proteins. It has been suggested that the vitamin K requirement of bone tissue is higher than that of the liver. Here we report that in rats very high doses of vitamin K affected neither the blood coagulation characteristics nor...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/s0021-9150(97)00087-7

    authors: Ronden JE,Groenen-van Dooren MM,Hornstra G,Vermeer C

    更新日期:1997-07-11 00:00:00

  • Angiotensin-converting enzyme gene polymorphism and common carotid stiffness. The Rotterdam study.

    abstract::The insertion/deletion (I/D) polymorphism of the ACE gene may be involved in structural arterial changes. Aim of the present study was to assess the relationship between the ACE I/D gene and vessel wall stiffness among older adults. The study was conducted within the Rotterdam study, a population-based cohort study in...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2004.01.012

    authors: Mattace-Raso FU,van der Cammen TJ,Sayed-Tabatabaei FA,van Popele NM,Asmar R,Schalekamp MA,Hofman A,van Duijn CM,Witteman JC

    更新日期:2004-05-01 00:00:00

  • Reduced systemic inflammatory response to implantation of sirolimus-eluting stents in patients with stable coronary artery disease.

    abstract::Stent implantation causes significant injury to the vascular wall, resulting in inflammatory activation. Although sirolimus-eluting stents (SES) have anti-inflammatory properties, their effect on periprocedural systemic inflammatory response has not been sufficiently investigated. Eighty-one patients with stable coron...

    journal_title:Atherosclerosis

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.atherosclerosis.2006.08.029

    authors: Kochiadakis GE,Marketou ME,Arfanakis DA,Sfiridaki K,Skalidis EI,Igoumenidis NE,Hamilos MI,Kolyvaki S,Chlouverakis G,Kantidaki E,Castanas E,Vardas PE

    更新日期:2007-10-01 00:00:00

  • Coronary heart disease in 'low risk' men.

    abstract::An attempt was made to explore the reasons why men develop coronary heart disease (CHD) despite being at low risk on the basis of established risk factors. A case control study was designed to take place after the end of a longitudinal study in which both low- and high-risk men who had developed CHD over the course of...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/0021-9150(83)90196-x

    authors: Heller RF,Miller NE,Wheeler MJ,Kind PR

    更新日期:1983-11-01 00:00:00

  • Quantitative trait locus on Chromosome 19 for circulating levels of intercellular adhesion molecule-1 in Mexican Americans.

    abstract::Circulating soluble intercellular adhesion molecule-1 (sICAM-1) is a biochemical marker of inflammation. We performed variance-components-based quantitative genetic analyses in SOLAR of sICAM-1 in 1170 individuals from Mexican American families in the San Antonio Family Heart Study. The trait is heritable (h(2)=0.50+/...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2006.10.005

    authors: Kent JW Jr,Mahaney MC,Comuzzie AG,Göring HH,Almasy L,Dyer TD,Cole SA,MacCluer JW,Blangero J

    更新日期:2007-12-01 00:00:00

  • 18Fluoride-based molecular imaging of coronary atherosclerosis in HIV infected patients.

    abstract:BACKGROUND AND AIMS:Molecular imaging with 18Fluorodeoxyglucose (FDG) and 18F-sodium-fluoride (NaF) captures arterial inflammation and micro-calcification and can reveal potentially unstable atherosclerotic plaques. METHODS:We performed FDG and NaF PET/CT imaging in two clinically similar cohorts of patients living wi...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2020.02.014

    authors: Guaraldi G,Milic J,Prandini N,Ligabue G,Esposito F,Ciusa G,Malagoli A,Scaglioni R,Besutti G,Beghetto B,Nardini G,Roncaglia E,Mussini C,Raggi P

    更新日期:2020-03-01 00:00:00

  • Transcriptional regulation of the human sterol 27-hydroxylase gene (CYP27) and promoter mapping.

    abstract::Recent evidence suggests that sterol 27-hydroxylase may play a role in cholesterol homeostasis and affect atherogenesis. The major objective of the study was to map and characterize the sterol 27-hydroxylase (CYP27) promoter region. Here we show that CYP27 gene has a TATA-less promoter and transcription initiates at a...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/s0021-9150(00)00654-7

    authors: Segev H,Honigman A,Rosen H,Leitersdorf E

    更新日期:2001-06-01 00:00:00

  • Smoking, inflammatory patterns and postprandial hypertriglyceridemia.

    abstract:BACKGROUND:Smoking is associated with increased postprandial hypertriglyceridemia (PPT). Inflammation and insulin resistance are potential "drivers" for this phenomenon. We tested whether inflammatory patterns and/or insulin resistance explain the effect of smoking on PPT. METHODS AND RESULTS:Men and women in the NHLB...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2008.08.005

    authors: Kabagambe EK,Ordovas JM,Tsai MY,Borecki IB,Hopkins PN,Glasser SP,Arnett DK

    更新日期:2009-04-01 00:00:00

  • Long-term effect of hyperlipidemic serum on the synthesis of glycosaminoglycans and on the rate of growth of rabbit aortic smooth muscle cells in culture.

    abstract::Rabbit aortic smooth muscle cells (SMCs) were successfully subcultured in 10% hyperlipidemic rabbit serum (HLS) for at least 9 passages. SMCs grown in HLS grew into higher cell densities than SMCs cultured in normolipidemic rabbit serum (NLS) for at least 4-5 passages in NLS and HLS, respectively. However, cells cultu...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/0021-9150(82)90127-7

    authors: Pietilä K

    更新日期:1982-03-01 00:00:00

  • Serum lipoproteins, sex hormones and sex hormone binding globulin in middle-aged men of different physical fitness and risk of coronary heart disease.

    abstract::Serum concentrations of lipoproteins, apolipoprotein A-I (Apo A-I), androgens, including biologically active free testosterone (free T), and sex hormone binding globulin (SHBG) and their associations were studied in 3 groups of men of different physical fitness and risk of CHD, consisting of male CHD patients, joggers...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/0021-9150(87)90275-9

    authors: Hämäläinen E,Tikkanen H,Härkönen M,Näveri H,Adlercreutz H

    更新日期:1987-10-01 00:00:00

  • Does cellular sex matter? Dimorphic transcriptional differences between female and male endothelial cells.

    abstract:OBJECTIVE:Significant sex differences exist in cardiovascular diseases. Although an impact of gonadal hormones is presumed, it is largely unknown whether sexually dimorphic gene expression also plays a role and whether cells themselves show intrinsic sex differences. METHODS:We performed whole genome expression analys...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2015.02.018

    authors: Lorenz M,Koschate J,Kaufmann K,Kreye C,Mertens M,Kuebler WM,Baumann G,Gossing G,Marki A,Zakrzewicz A,Miéville C,Benn A,Horbelt D,Wratil PR,Stangl K,Stangl V

    更新日期:2015-05-01 00:00:00

  • Effect of intessive plasmapheresis on the plasma cholesterol concentration with familial hypercholesterolemia.

    abstract::Plasmapheresis was studied as a means of reducing the serum cholesterol concentration in 3 hypercholesterolemic patients who each underwent courses of intensive plasmapheresis with removal of 250--500 ml of plasma each day for 5--9 days. In one homozygous Type II patient, the serum cholesterol concentration decreased ...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/0021-9150(78)90157-0

    authors: Apstein CS,Zilversmit DB,Lees RS,George PK

    更新日期:1978-10-01 00:00:00

  • Alteration in the availability of epoxyeicosatrienoic acids contributes with NO to the development of endothelial dysfunction in conduit arteries during aging.

    abstract:BACKGROUND AND AIMS:The mechanisms involved in endothelial dysfunction in humans during aging are largely unknown at the level of conduit arteries. We aimed to asses the role of NO and CYP450 epoxygenases-derived epoxyeicosatrienoic acids (EETs) in the regulation of endothelium-dependent flow-mediated dilatation of con...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2018.06.865

    authors: Wils J,Djerada Z,Roca F,Duflot T,Iacob M,Remy-Jouet I,Joannides R,Bellien J

    更新日期:2018-08-01 00:00:00

  • Effects of thrice weekly nocturnal hemodialysis on arterial stiffness.

    abstract:OBJECTIVE:In this study, we compared the changes in arterial stiffness in chronic hemodialysis patients treated with 8-h vs. 4-h thrice weekly in-center hemodialysis. METHODS:Sixty prevalent chronic hemodialysis patients assigned to 8-h nocturnal in-center thrice weekly HD (NHD) and 60 control cases assigned to 4-h th...

    journal_title:Atherosclerosis

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.atherosclerosis.2011.11.015

    authors: Demirci MS,Celik G,Ozkahya M,Tumuklu M,Toz H,Asci G,Duman S,Basci A,Kircelli F,Ozdogan O,Demirci C,Can L,Isik IO,Ok E,Long Dialysis Group.

    更新日期:2012-02-01 00:00:00

  • Impact of implanted bone marrow progenitor cell composition on limb salvage after cell implantation in patients with critical limb ischemia.

    abstract:OBJECTIVE:The aim of this study is to identify which factors influence limb salvage after bone marrow mononuclear cell implantation (BMI) in patients with chronic critical limb ischemia (CLI). METHODS:Thirteen no-option CLI patients treated with BMI were enrolled in the present study. Limb ischemia was assessed using ...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2009.08.028

    authors: Iso Y,Soda T,Sato T,Sato R,Kusuyama T,Omori Y,Shoji M,Koba S,Katagiri T,Kobayashi Y,Suzuki H

    更新日期:2010-03-01 00:00:00

  • The novel selective PPARα modulator (SPPARMα) pemafibrate improves dyslipidemia, enhances reverse cholesterol transport and decreases inflammation and atherosclerosis.

    abstract:BACKGROUND:Atherosclerosis is characterized by lipid accumulation and chronic inflammation in the arterial wall. Elevated levels of apolipoprotein (apo) B-containing lipoproteins are a risk factor for cardiovascular disease (CVD). By contrast, plasma levels of functional high-density lipoprotein (HDL) and apoA-I are pr...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2016.03.003

    authors: Hennuyer N,Duplan I,Paquet C,Vanhoutte J,Woitrain E,Touche V,Colin S,Vallez E,Lestavel S,Lefebvre P,Staels B

    更新日期:2016-06-01 00:00:00

  • Prostanoid and isoprostanoid pathways in atherogenesis.

    abstract::Atherosclerosis is a chronic inflammatory disease of the vasculature that is influenced by multiple factors and involves a complex interplay between some components of the bloodstream and the arterial wall. Among different circulating factors implicated in atherogenesis there is a large group of bioactive lipids calle...

    journal_title:Atherosclerosis

    pub_type: 杂志文章,评审

    doi:10.1016/j.atherosclerosis.2008.04.037

    authors: Praticò D

    更新日期:2008-11-01 00:00:00

  • Effects of statin therapy on the progression of carotid atherosclerosis: a systematic review and meta-analysis.

    abstract::Observational studies suggested that the progression of carotid atherosclerosis and plaques might be an independent risk factor for coronary artery disease (CAD) and stroke, prior researches of different dosage of statins therapy on the progression of carotid atherosclerosis in patients had small sample sizes and diff...

    journal_title:Atherosclerosis

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.atherosclerosis.2004.08.005

    authors: Kang S,Wu Y,Li X

    更新日期:2004-12-01 00:00:00

  • Elevated HDL is a risk factor for recurrent coronary events in a subgroup of non-diabetic postinfarction patients with hypercholesterolemia and inflammation.

    abstract::Recent studies demonstrate important roles for inflammation in development of atherosclerosis with current attention focusing on interactions of inflammation with traditional lipoprotein risk factors. Since the nature of such relationships is largely unknown, we sought to investigate interactions of inflammation with ...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2005.09.012

    authors: Corsetti JP,Zareba W,Moss AJ,Rainwater DL,Sparks CE

    更新日期:2006-07-01 00:00:00