Abstract:
:The relationship of ischaemic heart disease (IHD) to seasonal and latitude variation has prompted speculation that exposure to the ultraviolet component of solar radiation may reduce IHD risk. This hypothesis was partially tested by exposing 14 post-myocardial infarction patients to a 6 week course of artificial whole-body ultraviolet radiation (UVR). Serum lipoprotein and plasma coagulation factor concentrations were measured before and after the course of UVR. Results were compared with similar measurements from a placebo-controlled group of 13 post-myocardial patients. Despite a more than two-fold rise in mean serum 25-OHD, serum lipoprotein and plasma fibrinogen, antithrombin III and plasminogen concentrations did not change significantly in the UVR group. Significant but minor change in prothrombin time and thrombin time in the placebo group appear unlikely to be of biological significance. Seasonal and latitude variation in these IHD risk factors appear unrelated to corresponding variation in solar UVR exposure.
journal_name
Atherosclerosisjournal_title
Atherosclerosisauthors
Clark P,Cockburn F,Cowan RA,Czapla K,Dunnigan MG,Farish E,Hughes Edoi
10.1016/0021-9150(94)90142-2subject
Has Abstractpub_date
1994-05-01 00:00:00pages
65-9issue
1eissn
0021-9150issn
1879-1484pii
0021-9150(94)90142-2journal_volume
107pub_type
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