Abstract:
:The precise measurement of forces is one way to obtain deep insight into the fundamental interactions present in nature. In the context of neutral antimatter, the gravitational interaction is of high interest, potentially revealing new forces that violate the weak equivalence principle. Here we report on a successful extension of a tool from atom optics--the moiré deflectometer--for a measurement of the acceleration of slow antiprotons. The setup consists of two identical transmission gratings and a spatially resolving emulsion detector for antiproton annihilations. Absolute referencing of the observed antimatter pattern with a photon pattern experiencing no deflection allows the direct inference of forces present. The concept is also straightforwardly applicable to antihydrogen measurements as pursued by the AEgIS collaboration. The combination of these very different techniques from high energy and atomic physics opens a very promising route to the direct detection of the gravitational acceleration of neutral antimatter.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Aghion S,Ahlén O,Amsler C,Ariga A,Ariga T,Belov AS,Berggren K,Bonomi G,Bräunig P,Bremer J,Brusa RS,Cabaret L,Canali C,Caravita R,Castelli F,Cerchiari G,Cialdi S,Comparat D,Consolati G,Derking H,Di Domizio S,Di Ndoi
10.1038/ncomms5538subject
Has Abstractpub_date
2014-07-28 00:00:00pages
4538issn
2041-1723pii
ncomms5538journal_volume
5pub_type
杂志文章abstract::The three-dimensional structure of chromosomes plays an important role in gene expression regulation and also influences the repair of radiation-induced DNA damage. Genomic aberrations that disrupt chromosome spatial domains can lead to diseases including cancer, but how the 3D genome structure responds to DNA damage ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-20047-w
更新日期:2020-12-02 00:00:00
abstract::Tomatoes come in a multitude of shapes and flavors despite a narrow genetic pool. Here, we leverage whole-genome resequencing data available for 602 cultivated and wild accessions to determine the contribution of transposable elements (TEs) to tomato diversity. We identify 6,906 TE insertions polymorphisms (TIPs), whi...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-17874-2
更新日期:2020-08-13 00:00:00
abstract::Flexible barrier films preventing permeation of gases and moistures are important for many industries ranging from food to medical and from chemical to electronic. From this perspective, graphene has recently attracted particular interest because its defect-free monolayers are impermeable to all atoms and molecules. H...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms5843
更新日期:2014-09-11 00:00:00
abstract::The three-dimensional architecture of the genome affects genomic functions. Multiple genome architectures at different length scales, including chromatin loops, domains, compartments, and lamina- and nucleolus-associated regions, have been discovered. However, how these structures are arranged in the same cell and how...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-16732-5
更新日期:2020-06-09 00:00:00
abstract::Selective thermal emission in a useful range of energies from a material operating at high temperatures is required for effective solar thermophotovoltaic energy conversion. Three-dimensional metallic photonic crystals can exhibit spectral emissivity that is modified compared with the emissivity of unstructured metals...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms3630
更新日期:2013-01-01 00:00:00
abstract::The diversity in our genome is crucial to understanding the demographic history of worldwide populations. However, we have yet to know whether subtle genetic differences within a population can be disentangled, or whether they have an impact on complex traits. Here we apply dimensionality reduction methods (PCA, t-SNE...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-15194-z
更新日期:2020-03-26 00:00:00
abstract::The Tie receptors with their Angiopoietin ligands act as regulators of angiogenesis and vessel maturation. Tie2 exerts its functions through its supposed endothelial-specific expression. Yet, Tie2 is also expressed at lower levels by pericytes and it has not been unravelled through which mechanisms pericyte Angiopoiet...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms16106
更新日期:2017-07-18 00:00:00
abstract::5-Fluorouracil (5-FU) remains the first-line treatment for colorectal cancer (CRC). Although 5-FU initially de-bulks the tumor mass, recurrence after chemotherapy is the barrier to effective clinical outcomes for CRC patients. Here, we demonstrate that p53 promotes WNT3 transcription, leading to activation of the WNT/...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-19173-2
更新日期:2020-10-21 00:00:00
abstract::Stress granules (SG) are translationally silent sites of RNA triage induced by environmental stresses including viral infection. Here we show that HIV-1 Gag blocks SG assembly irrespective of eIF2α phosphorylation and even when SG assembly is forced by overexpression of Ras-GAP SH3 domain-binding protein (G3BP1) or TI...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms5819
更新日期:2014-09-17 00:00:00
abstract::Suppressor of Fused (SuFu), a tumour suppressor mutated in medulloblastoma, is a central player of Hh signalling, a pathway crucial for development and deregulated in cancer. Although the control of Gli transcription factors by SuFu is critical in Hh signalling, our understanding of the mechanism regulating this key e...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-03339-0
更新日期:2018-03-07 00:00:00
abstract::In Arabidopsis thaliana, CONSTANS (CO) plays an essential role in the regulation of photoperiodic flowering under long-day conditions. CO protein is stable only in the afternoon of long days, when it induces the expression of FLOWERING LOCUS T (FT), which promotes flowering. The blue-light photoreceptor FLAVIN-BINDING...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-02476-2
更新日期:2017-12-22 00:00:00
abstract::A new paradigm for cellulose depolymerization by fungi focuses on an oxidative mechanism involving cellobiose dehydrogenases (CDH) and copper-dependent lytic polysaccharide monooxygenases (LPMO); however, mechanistic studies have been hampered by the lack of structural information regarding CDH. CDH contains a haem-bi...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms8542
更新日期:2015-07-07 00:00:00
abstract::Albedo-a primary control on surface melt-varies considerably across the Greenland Ice Sheet yet the specific surface types that comprise its dark zone remain unquantified. Here we use UAV imagery to attribute seven distinct surface types to observed albedo along a 25 km transect dissecting the western, ablating sector...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-03353-2
更新日期:2018-03-14 00:00:00
abstract::Deep learning algorithms have been successfully used in medical image classification. In the next stage, the technology of acquiring explainable knowledge from medical images is highly desired. Here we show that deep learning algorithm enables automated acquisition of explainable features from diagnostic annotation-fr...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-13647-8
更新日期:2019-12-18 00:00:00
abstract::There are concerns that pneumococcal conjugate vaccines (PCVs) in sub-Saharan Africa sub-optimally interrupt Streptococcus pneumoniae vaccine-serotype (VT) carriage and transmission. Here we assess PCV carriage using rolling, prospective nasopharyngeal carriage surveys between 2015 and 2018, 3.6-7.1 years after Malawi...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-15786-9
更新日期:2020-05-06 00:00:00
abstract::Acoustical tweezers open major prospects in microbiology for cells and microorganisms contactless manipulation, organization and mechanical properties testing since they are biocompatible, label-free and have the potential to exert forces several orders of magnitude larger than their optical counterpart at equivalent ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-18000-y
更新日期:2020-08-25 00:00:00
abstract::Poly-(ADP-ribose) polymerase inhibitors (PARPi) selectively kill breast and ovarian cancers with defects in homologous recombination (HR) caused by BRCA1/2 mutations. There is also clinical evidence for the utility of PARPi in breast and ovarian cancers without BRCA mutations, but the underlying mechanism is not clear...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-09232-8
更新日期:2019-03-15 00:00:00
abstract::How to move efficiently is an optimal control problem, whose computational complexity grows exponentially with the horizon of the planned trajectory. Breaking a compound movement into a series of chunks, each planned over a shorter horizon can thus reduce the overall computational complexity and associated costs while...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms12176
更新日期:2016-07-11 00:00:00
abstract::Carbon-based three-dimensional aerographite networks, built from interconnected hollow tubular tetrapods of multilayer graphene, are ultra-lightweight materials recently discovered and ideal for advanced multifunctional applications. In order to predict the bulk mechanical behaviour of networks it is very important to...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms14982
更新日期:2017-04-12 00:00:00
abstract::Considerable progress in the fabrication of quasicrystals demonstrates that they can be realized in a broad range of materials. However, the development of chemistries enabling direct experimental observation of early quasicrystal growth pathways remains challenging. Here, we report the synthesis of four surfactant-di...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-00351-8
更新日期:2017-08-15 00:00:00
abstract::Recent years have seen great advances in the development of synthetic self-assembling molecular systems. Designing out-of-equilibrium architectures, however, requires a more subtle control over the thermodynamics and kinetics of reactions. We propose a mechanism for enhancing the thermodynamic drive of DNA strand-disp...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-16353-y
更新日期:2020-05-22 00:00:00
abstract::Major depressive disorder is associated with abnormalities in the brain and the immune system. Chronic stress in animals showed that epigenetic and inflammatory mechanisms play important roles in mediating resilience and susceptibility to depression. Here, through a high-throughput screening, we identify two phytochem...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-02794-5
更新日期:2018-02-02 00:00:00
abstract::The lattice dynamics and high-temperature structural transition in SnS and SnSe are investigated via inelastic neutron scattering, high-resolution Raman spectroscopy and anharmonic first-principles simulations. We uncover a spectacular, extreme softening and reconstruction of an entire manifold of low-energy acoustic ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-18121-4
更新日期:2020-09-04 00:00:00
abstract::Although influenza viruses lead to severe illness in high-risk populations, host genetic factors associated with severe disease are largely unknown. As the HLA-A*68:01 allele can be linked to severe pandemic 2009-H1N1 disease, we investigate a potential impairment of HLA-A*68:01-restricted CD8+ T cells to mount robust...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-13346-4
更新日期:2019-12-06 00:00:00
abstract::Aerobic methane oxidation is catalyzed by particulate methane monooxygenase (pMMO), a copper-dependent, membrane metalloenzyme composed of subunits PmoA, PmoB, and PmoC. Characterization of the copper active site has been limited by challenges in spectroscopic analysis stemming from the presence of multiple copper bin...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-10590-6
更新日期:2019-06-17 00:00:00
abstract::Ubiquitylation of histone H2B at lysine residue 120 (H2BK120ub) is a prominent histone posttranslational modification (PTM) associated with the actively transcribed genome. Although H2BK120ub triggers several critical downstream histone modification pathways and changes in chromatin structure, less is known about the ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-03895-5
更新日期:2018-04-11 00:00:00
abstract::We have determined the cryo-electron microscopic (cryo-EM) structures of two archaeal type IV pili (T4P), from Pyrobaculum arsenaticum and Saccharolobus solfataricus, at 3.8 Å and 3.4 Å resolution, respectively. This triples the number of high resolution archaeal T4P structures, and allows us to pinpoint the evolution...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-17268-4
更新日期:2020-07-09 00:00:00
abstract::Large reductions in the thermal conductivity of thin silicon membranes have been demonstrated in various porous structures. However, the role of coherent boundary scattering in such structures has become a matter of some debate. Here we report on the first experimental observation of coherent phonon boundary scatterin...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms8228
更新日期:2015-06-24 00:00:00
abstract::Caffeine is a major component of xanthine alkaloids and commonly consumed in many popular beverages. Due to its occasional side effects, reduction of caffeine in a natural way is of great importance and economic significance. Recent studies reveal that caffeine can be converted into non-stimulatory theacrine in the ra...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-15324-7
更新日期:2020-03-19 00:00:00
abstract::Winter Eurasian cooling after the mid-1990s has been verified by numerous studies, although in recent decades, the mid-latitudes of the Northern Hemisphere have been rapidly warming globally. Because the cooling is not uniform at different spatial and temporal scales, over time, this change may not truly reflect the n...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-19014-2
更新日期:2020-10-15 00:00:00