T-cell non-Hodgkin lymphoma in human immunodeficiency virus-1-infected individuals.

abstract：:Hairy cell leukemia is a chronic lymphoproliferative disorder characterized clinically by splenomegaly and cytopenias. Spontaneous remissions are rare and splenectomy is often performed when the blood counts worsen and cause symptoms. Three of our patients with hairy cell leukemia developed recurrent pancytopenia and ...

journal_title：American journal of hematology

authors： Keefer MJ,Weber MJ,Bottomley SS,Solanki DL,Hosty TA

更新日期：1987-07-01 00:00:00

abstract：:The second generation BCR/ABL kinase inhibitor nilotinib is increasingly used for the treatment of imatinib-resistant chronic myeloid leukemia (CML). So far, nilotinib is considered a well-tolerated drug with little if any side effects, although an increase in the fasting glucose level has been reported. We examined a...

journal_title：American journal of hematology

authors： Aichberger KJ,Herndlhofer S,Schernthaner GH,Schillinger M,Mitterbauer-Hohendanner G,Sillaber C,Valent P

更新日期：2011-07-01 00:00:00

abstract：:We recently defined event-free survival at 24 months (EFS24) as a clinically relevant outcome for patients with DLBCL. Patients who fail EFS24 have very poor overall survival, while those who achieve EFS24 have a subsequent overall survival equivalent to that of the age- and sex-matched general population. Here, we de...

journal_title：American journal of hematology

authors： Maurer MJ,Jais JP,Ghesquières H,Witzig TE,Hong F,Haioun C,Thompson CA,Thieblemont C,Micallef IN,Porrata LF,Ribrag V,Nowakowski GS,Casasnovas O,Bologna S,Morschhauser F,Morrison VA,Peterson BA,Macon WR,Copie-Bergman C

更新日期：2016-02-01 00:00:00

abstract：:We have characterized another subset of acute nonlymphocytic leukemia (ANLL) based on the cytogenetic and morphologic findings in a group of nine patients. Five patients had chromosomal analyses performed at the University of Chicago, two patients were studied at the All-Union Cancer Research Center in Moscow, and one...

journal_title：American journal of hematology

authors： Pearson MG,Vardiman JW,Le Beau MM,Rowley JD,Schwartz S,Kerman SL,Cohen MM,Fleischman EW,Prigogina EL

更新日期：1985-04-01 00:00:00

abstract：:By using Dexter-type long-term marrow cultures (D-LTMC), it has been shown previously that hematopoietic progenitor cells (HPC) from patients with aplastic anemia (AA) have a deficient proliferation in vitro. The studies reported to date, however, have focused exclusively on granulomonocytic progenitors and no informa...

journal_title：American journal of hematology

authors： Gómez-Morales E,Martinez-Jaramillo G,Sánchez-Valle E,Valencia-Plata I,Arana-Trejo RM,Castro MA,Pizzuto-Chávez J,Mayani H

更新日期：1998-10-01 00:00:00

abstract：:In this descriptive study, all 425 reports were included concerning drug-associated agranulocytosis as registered between 1974 and 1994 in the files of the Drug Safety Unit of the Dutch Inspectorate for Health Care. All reports were analysed as to the probability of agranulocytosis or neutropenia according to previous...

journal_title：American journal of hematology

authors： van der Klauw MM,Wilson JH,Stricker BH

更新日期：1998-03-01 00:00:00

abstract：:Everolimus is an oral antineoplastic agent that targets the raptor mammalian target of rapamycin (mTORC1). The phosphatidylinositol 3-kinase/mTOR signal transduction pathway has been demonstrated to be activated in tumor samples from patients with Hodgkin lymphoma (HL). The goal of this trial was to learn the antitumo...

journal_title：American journal of hematology

authors： Johnston PB,Inwards DJ,Colgan JP,Laplant BR,Kabat BF,Habermann TM,Micallef IN,Porrata LF,Ansell SM,Reeder CB,Roy V,Witzig TE

更新日期：2010-05-01 00:00:00

abstract：:Induction of carbonic anhydrase isozyme I (CA-I) by erythropoietin or hemin was investigated using erythroleukemia (K562) cells. Immunological estimation and purification of carbonic anhydrases showed that untreated K562 cells contained only carbonic anhydrase isozyme II(CA-II), while incubation of the cells with 2 un...

journal_title：American journal of hematology

authors： Kondo T,Sakai M,Isobe H,Taniguchi N,Nishi S,Kawakami Y

更新日期：1991-11-01 00:00:00

abstract：:Endothelin-1 (Et-1) is a vasoconstrictor produced by endothelial and vascular smooth muscle cells in response to hypoxia, which induces hypertrophy in cultured cardiac myocytes. We measured plasma Et-1 levels and left ventricular dimensions in 13 patients with sickle cell anemia (SCD) and in 12 African-American contro...

journal_title：American journal of hematology

authors： Werdehoff SG,Moore RB,Hoff CJ,Fillingim E,Hackman AM

更新日期：1998-07-01 00:00:00

abstract：:Cobalamin derivatives serve as coenzymes for the body's two cobalamin-dependent enzymes--adenosylcobalamin-dependent methylmalonyl CoA mutase, and methylcobalamin-dependent methionine methyltransferase. This essay reviews, in brief form and in personal terms, the history, beginning in the mid-1950s, of how these enzym...

journal_title：American journal of hematology

authors： Beck WS

更新日期：1990-06-01 00:00:00

abstract：:Red blood cells from patients with sickle cell disease (SS RBC) adhere to laminin and over-express the high-affinity laminin receptor basal cell adhesion molecule/Lutheran protein (B-CAM/LU). This receptor has recently been shown to undergo activation in vitro through a protein kinase A-dependent mechanism. Low-densit...

journal_title：American journal of hematology

authors： Zen Q,Batchvarova M,Twyman CA,Eyler CE,Qiu H,De Castro LM,Telen MJ

更新日期：2004-02-01 00:00:00

abstract：:Graft failure is a life-threatening complication after allogeneic hematopoietic stem cell transplantation (HSCT). Graft failure is more prevalent after umbilical cord blood transplantation (UCBT) compared with conventional adult stem cell sources. We identified 21 consecutive patients who experienced graft failure aft...

journal_title：American journal of hematology

authors： Singh H,Nikiforow S,Li S,Ballen KK,Spitzer TR,Soiffer R,Antin JH,Cutler C,Chen YB

更新日期：2014-12-01 00:00:00

abstract：:Platelet-rich plasma were treated with increasing concentrations of vitamin E (alpha-tocopherol). Washed platelets were exposed to oxidized low density lipoprotein (LDL) and examined by aggregometry and electron microscopy. The treatment of washed platelets by oxidized LDL induced morphological signs of activation lik...

journal_title：American journal of hematology

authors： Szuwart T,Dierichs RB,Zhao B

更新日期：1999-03-01 00:00:00

abstract：:We report a case of a 61-year-old man with head and neck cancer who presented with pancytopenia two months after the completion of his chemotherapy and was diagnosed with myelodysplasia on the basis of two bone marrow examinations, before the correct diagnosis of visceral leishmaniasis was established with splenectomy...

journal_title：American journal of hematology

authors： Kopterides P,Halikias S,Tsavaris N

更新日期：2003-11-01 00:00:00

abstract：:The content of peripheral blood B cells (B1+) was reduced in patients of multiple myeloma (MM) and not in those with benign monoclonal gammopathy (BMG) compared to normal donors (P less than 0.01). This observation correlated with the suppression of synthesis of normal immunoglobulin (Ig) in MM. Thus, cytokine activit...

journal_title：American journal of hematology

authors： Kawano M,Iwato K,Asaoku H,Tanabe O,Tanaka H,Ishikawa H,Kuramoto A

更新日期：1989-02-01 00:00:00

abstract：:Tumor cells of 14 cases of non-Hodgkin lymphomas and 2 cases of Hodgkin disease were tested for the presence of the transferrin receptor (CD71) by flow cytofluorimetry before 67gallium imaging. It appeared that expression of CD71 phenotype was closely related to the positivity of gallium scan before therapy. We feel t...

journal_title：American journal of hematology

authors： Feremans W,Bujan W,Neve P,Delville JP,Schandene L

更新日期：1991-03-01 00:00:00

abstract：:Indolent non-hodgkin lymphomas (iNHL) are a rare cause of monoclonal immunoglobulin deposits-related glomerulopathy (mIgGN). In patients with iNHL-related mIgGN, whether treatment should include either single or a combination of drug(s) to target the malignant clone and renal inflammation remains elusive. In this retr...

journal_title：American journal of hematology

authors： Perry M,Delarche A,Ribes D,Vergez F,Guilbeau-Frugier C,Laurent C,Huart A,Tavitian S,El Hachem H,Oberic L,Chauveau D,Michallet AS,Ysebaert L,Faguer S

更新日期：2014-10-01 00:00:00

abstract：:A 64-year-old woman with mild bilateral parotid gland swelling and bilateral lower extremity purpura was admitted for evaluation of xerostomia and pancytopenia. The patient had an increased erythrocyte sedimentation rate, pancytopenia, and positive tests for antibodies to nuclear antigen, SS-A, and SS-B. Impaired cell...

journal_title：American journal of hematology

authors： Seki T,Kiyosawa K,Monno S,Imai Y,Furukawa K,Kumazawa S,Ota M,Saito H,Furuta S,Nakahata T

更新日期：1993-07-01 00:00:00

abstract：:Persistent thrombocytopenia after stem cell transplantation can lead to increased morbidity and mortality [1,2]. The underlying causes are often multifactorial in this patient population [3,4]. In autologous transplantation, thrombocytopenia is usually a result of poor engraftment or a sign of impending disease relaps...

journal_title：American journal of hematology

authors： Reid R,Bennett JM,Becker M,Chen Y,Milner L,Phillips GL 2nd,Liesveld J

更新日期：2012-07-01 00:00:00

abstract：:Pulmonary hypertension (PH) of sickle cell disease (SCD), as defined by a tricuspid regurgitant jet velocity by echocardiogram of >or=2.5 m/sec, occurs in approximately 1/3 of HbSS adults and is an independent risk factor for mortality. Although studies of the past few years have greatly expanded our knowledge of the ...

journal_title：American journal of hematology

authors： Klings ES

更新日期：2008-01-01 00:00:00

abstract：:An HTLV-I-seronegative case of adult T-cell leukemia (ATL) carrying the HTLV-I genome is reported. Screening serological tests were negative and Western blot analysis revealed only a faint band for HTLV-I p24. Polymerase chain reaction (PCR) disclosed the presence of HTLV-I gag, pol, env, pX, and LTR sequences in the ...

journal_title：American journal of hematology

authors： Kubota T,Ikezoe T,Hakoda E,Sawada T,Taguchi H,Miyoshi I

更新日期：1996-10-01 00:00:00

abstract：:The role of leukapheresis was explored in the management of anaemia and thrombocytopenia complicating the accumulation of lymphoid cells in patients with chronic lymphocytic leukaemia and lymphoma. The aim of this study was to determine the efficiency of this procedure in correcting these complicating features and to ...

journal_title：American journal of hematology

authors： Cooper IA,Ding JC,Adams PB,Quinn MA,Brettell M

更新日期：1979-01-01 00:00:00

abstract：:Venous thromboembolism (VTE) is a common cause of morbidity and mortality among patients with multiple myeloma (MM). The International Myeloma Working Group (IMWG) developed guidelines recommending primary thromboprophylaxis, in those identified at high-risk of VTE by the presence of risk factors. The National Compreh...

journal_title：American journal of hematology

authors： Sanfilippo KM,Luo S,Wang TF,Fiala M,Schoen M,Wildes TM,Mikhael J,Kuderer NM,Calverley DC,Keller J,Thomas T,Carson KR,Gage BF

更新日期：2019-11-01 00:00:00

abstract：:Fibrillar granules (FGs) represent neutrophilic primary granules containing clustered filaments. We investigated neutrophils in the bone marrow obtained from 17 patients with chronic myeloproliferative disorders (CMPD) by electron microscopy. FG-positive neutrophils were seen in 15 of the 17 CMPDs with varying frequen...

journal_title：American journal of hematology

authors： Takemori N,Hirai K,Onodera R,Saito N,Miyokawa N

更新日期：1994-11-01 00:00:00

abstract：DISEASE OVERVIEW:The myelodysplastic syndromes (MDS) are a very heterogeneous group of myeloid disorders characterized by peripheral blood cytopenias and increased risk of transformation to acute myelogenous leukemia (AML). MDS occurs more frequently in older males and in individuals with prior exposure to cytotoxic th...

journal_title：American journal of hematology

authors： Garcia-Manero G

更新日期：2015-09-01 00:00:00

abstract：:Ten previously untreated elderly patients with hypocellular acute leukemia received a low dose of cytosine arabinoside (Ara-C), 10 mg/m2 injected subcutaneously every 12 hours for 14-28 days. Six patients achieved a complete remission (CR) for periods ranging for 6-23 months (median 8.5 months) and the others had a pa...

journal_title：American journal of hematology

authors： Kanamori H,Maruta A,Miyashita H,Harano H,Fukawa H,Matsuzaki M,Motomura S,Mohri H,Kodama F,Okubo T

更新日期：1992-01-01 00:00:00

abstract：:A single-strand conformation polymorphism (SSCP) analysis of polymerase chain reaction (PCR)-amplified products of immunoglobulin (Ig) heavy chain rearrangements can be used to analyze B cell clonalities and clonal identities of B cells from different samples. However, the usefulness of the PCR-SSCP analysis is not fu...

journal_title：American journal of hematology

authors： Shiokawa S,Nishimura J,Uike N,Saburi Y,Suehiro T,Yamamoto K

更新日期：1999-10-01 00:00:00

abstract：:Venous thromboembolism (VTE) is common but often unrecognized in medically ill patients. Over the past 5 years, three large-scale placebo-controlled trials enrolling a total of 5500 medically ill patients have highlighted the risk of VTE in this group. These trials have helped to define a specific at-risk patient prof...

journal_title：American journal of hematology

authors： Stinnett JM,Pendleton R,Skordos L,Wheeler M,Rodgers GM

更新日期：2005-03-01 00:00:00

abstract：:We report the case of a 59-year-old woman with Durie-Salmon stage IIIB IgGkappa multiple myeloma (MM), who presented 83 days after autologous hematopoietic stem cell transplant (HSCT) with multiple subcutaneous plasmacytomas. These lesions were confined exclusively to sites where the patient had sustained local trauma...

journal_title：American journal of hematology

authors： Rosenblum MD,Bredeson CN,Chang CC,Rizzo JD

更新日期：2003-04-01 00:00:00

abstract：:We present a case of chronic tonsillitis in a patient with chronic lymphocytic leukemia. Despite empiric radiation and antibiotic therapy, the patient's sore throat and tonsillar enlargement persisted. Excisional biopsy of the involved tonsil revealed the presence of Cryptococcus neoformans. Blood cultures also yielde...

journal_title：American journal of hematology

authors： Korvick J,Yu VL

更新日期：1987-08-01 00:00:00