Peripheral blood remission of hairy cell leukemia after transfusion hepatitis.

Abstract:

:Hairy cell leukemia is a chronic lymphoproliferative disorder characterized clinically by splenomegaly and cytopenias. Spontaneous remissions are rare and splenectomy is often performed when the blood counts worsen and cause symptoms. Three of our patients with hairy cell leukemia developed recurrent pancytopenia and transfusion-dependent anemia after splenectomy. Each subsequently acquired transfusion hepatitis and in two patients marked hematologic improvement was noted within 2 months. Complete peripheral blood remission occurred within 17 months in all patients although bone marrow infiltration with hairy cells persisted. One patient remains in remission for 12 years; the other two succumbed to infectious illnesses but with normal blood counts. The mechanism by which hepatitis virus induces hematologic recovery in patients with hairy cell leukemia is unknown but may involve augmentation of the interferon system.

journal_name

Am J Hematol

authors

Keefer MJ,Weber MJ,Bottomley SS,Solanki DL,Hosty TA

doi

10.1002/ajh.2830250307

subject

Has Abstract

pub_date

1987-07-01 00:00:00

pages

277-84

issue

3

eissn

0361-8609

issn

1096-8652

journal_volume

25

pub_type

杂志文章
  • In vitro synthesis of hemoglobin and hemoglobin chains in the BFUe-derived colonies form person with alpha- or beta-thalassemia.

    abstract::The synthesis of alpha and non-alpha chains of human hemoglobin (Hb) was studied in reticulocytes and in BFUe-derived cell colonies from patients with alpha chain or beta chain deficiencies. The subjects included normal adults (alpha alpha/alpha alpha) with or without a beta chain variant (Hb S, Hb Leslie) or an alpha...

    journal_title:American journal of hematology

    pub_type: 杂志文章

    doi:10.1002/ajh.2830100302

    authors: Huisman TH,Reese AL,Webber B,Okonjo K,Altay C,Felice AE

    更新日期:1981-01-01 00:00:00

  • Plasmodium vivax malaria complicated by hemophagocytic syndrome in an immunocompetent serviceman.

    abstract::We describe a 23-year-old retired military officer who was immunocompetent but diagnosed with hemophagocytic syndrome (HPS) by Plasmodium vivax infection. Initially, the patient was suspected to have toxic hepatitis related to heavy drinking. But abnormal hematologic findings required a further bone marrow examination...

    journal_title:American journal of hematology

    pub_type: 杂志文章,评审

    doi:10.1002/ajh.10390

    authors: Park TS,Oh SH,Choi JC,Kim HH,Chang CL,Son HC,Lee EY

    更新日期:2003-10-01 00:00:00

  • Bone marrow histological findings in systemic lupus erythematosus with hematologic abnormalities: a clinicopathological study.

    abstract:BACKGROUND:The histopathologic features characterizing the involvement of the bone marrow (BM) in systemic lupus erythematosus (SLE) have not been systematically analyzed to date. OBJECTIVES:The aim of this study was to assess morphologic and immunohistochemical characteristics of BM involvement in SLE. PATIENTS AND ...

    journal_title:American journal of hematology

    pub_type: 杂志文章

    doi:10.1002/ajh.20593

    authors: Voulgarelis M,Giannouli S,Tasidou A,Anagnostou D,Ziakas PD,Tzioufas AG

    更新日期:2006-08-01 00:00:00

  • Test of the month: The chromogenic antifactor Xa assay.

    abstract::As the number of anticoagulant drugs increases and new ones are brought to market, the utility of the routine screening coagulation tests of today--namely the prothrombin time and activated partial thromboplastin time--will be significantly reduced in many clinical situations. Although the new anticoagulants are desig...

    journal_title:American journal of hematology

    pub_type: 杂志文章

    doi:10.1002/ajh.22222

    authors: Gehrie E,Laposata M

    更新日期:2012-02-01 00:00:00

  • Erythrocyte incorporation of ingested stable isotope of iron (58Fe).

    abstract::Because of a possible hazard from the use of radioisotopes to determine iron absorption by infants, the use of stable isotopes for this purpose has much appeal. We have applied the method of inductively coupled plasma mass spectrometry (ICP/MS) to determine the mass ratio, 58Fe/57Fe, in blood before and after oral adm...

    journal_title:American journal of hematology

    pub_type: 杂志文章

    doi:10.1002/ajh.2830210307

    authors: Janghorbani M,Ting BT,Fomon SJ

    更新日期:1986-03-01 00:00:00

  • Clinical characteristics and prognostic factors in multiple myeloma patients with light chain deposition disease.

    abstract::Light chain deposition disease (LCDD) is characterized by monotypic immunoglobulin depositions which will eventually lead to loss of organ function if left untreated. While the kidney is almost always affected, the presence and degree of LCDD in other organs vary. Ten to thirty percent of LCDD patients have underlying...

    journal_title:American journal of hematology

    pub_type: 杂志文章

    doi:10.1002/ajh.24756

    authors: Mohan M,Buros A,Mathur P,Gokden N,Singh M,Susanibar S,Jo Kamimoto J,Hoque S,Radhakrishnan M,Matin A,Davis C,Grazziutti M,Thanendrarajan S,van Rhee F,Zangari M,Davies F,Morgan G,Epstein J,Barlogie B,Schinke C

    更新日期:2017-08-01 00:00:00

  • Laboratory evaluation of clopidogrel responsiveness by platelet function and genetic methods.

    abstract::Clopidogrel is a widely used antiplatelet agent that irreversibly inhibits platelet P2Y12 ADP receptors after conversion to an active metabolite. There are a number of laboratory tests capable of detecting clopidogrel-induced platelet inhibition and published literature correlates suboptimal clopidogrel response to ad...

    journal_title:American journal of hematology

    pub_type: 杂志文章,评审

    doi:10.1002/ajh.22112

    authors: Smock KJ,Saunders PJ,Rodgers GM,Johari V

    更新日期:2011-12-01 00:00:00

  • Bone marrow cellularity at day 14 is the most important predictive factor for response in patients with AML who require double-induction chemotherapy: Analysis from a large, single institution experience.

    abstract::In patients with acute myeloid leukemia (AML), the presence of residual disease at day 14 after primary induction therapy warrants consideration of a second induction cycle. However, data to guide retreatment decisions in such patients are presently limited. Here, we retrospectively reviewed data from 176 patients wit...

    journal_title:American journal of hematology

    pub_type: 杂志文章

    doi:10.1002/ajh.24627

    authors: Griffin PT,Komrokji RS,Sweet K,Al Ali NH,Padron E,Kubal TE,List AF,Lancet JE

    更新日期:2017-03-01 00:00:00

  • Is sickle cell crisis a thrombotic event?

    abstract::Although large vessel thrombi are occasionally reported in patients with homozygous sickle cell disease, the role of intravascular coagulation in typical pain crises is controversial. Therefore, we studied 24 sickle cell patients during and between episodes of pain crisis, using several sensitive tests of hemostasis. ...

    journal_title:American journal of hematology

    pub_type: 杂志文章

    doi:10.1002/ajh.2830230403

    authors: Green D,Scott JP

    更新日期:1986-12-01 00:00:00

  • Direct detection of beta thalassemic mutations: use of biotin-labelled allele specific probes.

    abstract::Mutations at positions beta IVS1-6, beta IVS1-110, and beta 39 of the beta globin gene are responsible for the three most common thalassemic genes in the Mediterranean population. The polymerase chain reaction (PCR) was employed to amplify a 536 base pair segment surrounding this region. Nonradioactive labelling of an...

    journal_title:American journal of hematology

    pub_type: 杂志文章

    doi:10.1002/ajh.2830340213

    authors: Hendy JG,Cauchi MN

    更新日期:1990-06-01 00:00:00

  • Clarithromycin (Biaxin)-lenalidomide-low-dose dexamethasone (BiRd) versus lenalidomide-low-dose dexamethasone (Rd) for newly diagnosed myeloma.

    abstract::The objective of this case-matched study was to compare the efficacy and toxicity of the addition of clarithromycin (Biaxin) to lenalidomide/low-dose dexamethasone (BiRd) vs. lenalidomide/low-dose dexamethasone (Rd) for newly diagnosed myeloma. Data from 72 patients treated at the New York Presbyterian Hospital-Cornel...

    journal_title:American journal of hematology

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1002/ajh.21777

    authors: Gay F,Rajkumar SV,Coleman M,Kumar S,Mark T,Dispenzieri A,Pearse R,Gertz MA,Leonard J,Lacy MQ,Chen-Kiang S,Roy V,Jayabalan DS,Lust JA,Witzig TE,Fonseca R,Kyle RA,Greipp PR,Stewart AK,Niesvizky R

    更新日期:2010-09-01 00:00:00

  • Short telomere length is associated with NOTCH1/SF3B1/TP53 aberrations and poor outcome in newly diagnosed chronic lymphocytic leukemia patients.

    abstract::Most previous studies on telomere length (TL) in chronic lymphocytic leukemia (CLL) are based on referral cohorts including a high proportion of aggressive cases. Here, the impact of TL was analyzed in a population-based cohort of newly diagnosed CLL (n = 265) and in relation to other prognostic markers. Short telomer...

    journal_title:American journal of hematology

    pub_type: 临床试验,杂志文章

    doi:10.1002/ajh.23466

    authors: Mansouri L,Grabowski P,Degerman S,Svenson U,Gunnarsson R,Cahill N,Smedby KE,Geisler C,Juliusson G,Roos G,Rosenquist R

    更新日期:2013-08-01 00:00:00

  • Hermansky-Pudlak syndrome: correction of bleeding time by 1-desamino-8D-arginine vasopressin.

    abstract::The effect of the synthetic vasopressin derivative 1-desamino-8D-arginine vasopressin (DDAVP = desmopressin) on bleeding time was studied in three patients with Hermansky Pudlak syndrome. A good response was observed in this type of storage pool disease. DDAVP might be useful in managing the bleeding disorder found in...

    journal_title:American journal of hematology

    pub_type: 杂志文章

    doi:10.1002/ajh.2830300307

    authors: Wijermans PW,van Dorp DB

    更新日期:1989-03-01 00:00:00

  • Overexpression of cyclooxygenase-2 in multiple myeloma: association with reduced survival.

    abstract::Cyclooxygenases (COX) are key enzymes in the conversion of arachidonic acid to prostaglandins. Several studies have shown a relation between angiogenesis and COX-2 expression. Elevated expression of cyclooxygenase-2 (COX-2), however, has not been reported in multiple myeloma (MM) in the literature. The aim of this stu...

    journal_title:American journal of hematology

    pub_type: 杂志文章

    doi:10.1002/ajh.20460

    authors: Cetin M,Buyukberber S,Demir M,Sari I,Sari I,Deniz K,Eser B,Altuntas F,Camci C,Oztürk A,Turgut B,Vural O,Unal A

    更新日期:2005-11-01 00:00:00

  • Sickle red cell calcium metabolism: studies on Ca2+-Mg2+ATPase and Ca-binding properties of sickle red cell membranes.

    abstract::Sickle (Hb SS) red cells, preloaded with 45Ca by reversal of hemolysis, exhibit an incomplete 45Ca extrusion, retaining approximately four times more 45Ca than normal cells. Studies indicated that neither the reduction in Hb SS cell Ca2+-Mg2+ ATPase activity (84% of normal) nor the activation of Ca2+-Mg2+ ATPase by ca...

    journal_title:American journal of hematology

    pub_type: 杂志文章

    doi:10.1002/ajh.2830080406

    authors: Litosch I,Lee KS

    更新日期:1980-01-01 00:00:00

  • Fetal lamb coagulation system during birth asphyxia.

    abstract::Levels of many coagulation factors are low in the healthy infant and even lower in the asphyxiated premature infant. We investigated whether a brief exposure to asphyxia at the time of birth causes the activation and consumption of coagulation factors. Following delivery by caesarean section, premature lambs were asph...

    journal_title:American journal of hematology

    pub_type: 杂志文章

    doi:10.1002/ajh.2830280317

    authors: Andrew M,O'Brodovich H,Mitchell L

    更新日期:1988-07-01 00:00:00

  • Cardiopulmonary complications leading to premature deaths in adult patients with sickle cell disease.

    abstract::Sickle cell disease (SCD) is associated with early mortality. We sought to determine the incidence, cause, and risk factors for death in an adult population of patients with SCD. All patients aged >/=18 years seen at the Adult Sickle Cell Center at Duke University Medical Center between January 2000 and April 2005 wer...

    journal_title:American journal of hematology

    pub_type: 杂志文章

    doi:10.1002/ajh.21569

    authors: Fitzhugh CD,Lauder N,Jonassaint JC,Telen MJ,Zhao X,Wright EC,Gilliam FR,De Castro LM

    更新日期:2010-01-01 00:00:00

  • Monocytic leukemia cutis diagnosed simultaneously with refractory anemia with monocytosis: a case report.

    abstract::A case of leukemia cutis (LC) of monocytic lineage in a patient with myelodysplastic syndrome (MDS) is presented. Cutaneous infiltrates were recognized concurrent with diagnosis of refractory anemia (RA) with monocytosis. Skin infiltrates subsequently spontaneously regressed although MDS progressed with increasing mon...

    journal_title:American journal of hematology

    pub_type: 杂志文章

    doi:10.1002/1096-8652(200102)66:2<120::AID-AJH1027>3.0

    authors: Yavorkovsky LL,Zain J,Wu CD,Trivelli L,Cook P

    更新日期:2001-02-01 00:00:00

  • Deficient proliferation of myeloid, erythroid, and multipotent progenitor cells in long-term marrow cultures from patients with aplastic anemia treated with immunosuppressive therapy.

    abstract::By using Dexter-type long-term marrow cultures (D-LTMC), it has been shown previously that hematopoietic progenitor cells (HPC) from patients with aplastic anemia (AA) have a deficient proliferation in vitro. The studies reported to date, however, have focused exclusively on granulomonocytic progenitors and no informa...

    journal_title:American journal of hematology

    pub_type: 杂志文章

    doi:10.1002/(sici)1096-8652(199810)59:2<149::aid-ajh8>

    authors: Gómez-Morales E,Martinez-Jaramillo G,Sánchez-Valle E,Valencia-Plata I,Arana-Trejo RM,Castro MA,Pizzuto-Chávez J,Mayani H

    更新日期:1998-10-01 00:00:00

  • Rituximab-cyclophosphamide-dexamethasone is highly effective in patients with monoclonal Ig deposit-related glomerulopathy and indolent non-Hodgkin lymphomas.

    abstract::Indolent non-hodgkin lymphomas (iNHL) are a rare cause of monoclonal immunoglobulin deposits-related glomerulopathy (mIgGN). In patients with iNHL-related mIgGN, whether treatment should include either single or a combination of drug(s) to target the malignant clone and renal inflammation remains elusive. In this retr...

    journal_title:American journal of hematology

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1002/ajh.23798

    authors: Perry M,Delarche A,Ribes D,Vergez F,Guilbeau-Frugier C,Laurent C,Huart A,Tavitian S,El Hachem H,Oberic L,Chauveau D,Michallet AS,Ysebaert L,Faguer S

    更新日期:2014-10-01 00:00:00

  • Assessment of alkaline phosphatase on the surface membrane of neutrophils by immunofluorescence.

    abstract::Expression of alkaline phosphatase (ALP) on the surface membrane of neutrophils (mNAP) was studied by immunofluorescence using an anti-ALP monoclonal antibody. Fluorescent intensity distribution of mNAP was analyzed using FACS (fluorescence-activated cell sorter). The mean fluorescent intensity (MFI) of the mNAP in th...

    journal_title:American journal of hematology

    pub_type: 杂志文章

    doi:10.1002/(sici)1096-8652(199901)60:1<12::aid-ajh3>3

    authors: Shibano M,Machii T,Nishimori Y,Nakamoto I,Ueda E,Masuhara K,Kitani T

    更新日期:1999-01-01 00:00:00

  • Utilizing multiparametric flow cytometry in the diagnosis of patients with primary plasma cell leukemia.

    abstract::The diagnosis of primary plasma cell leukemia (pPCL) has been made by quantifying circulating plasma cells (cPCs) morphologically on a peripheral blood (PB) smear. However, this technique is not sufficiently sensitive. Multiparametric flow cytometry (MFC) provides a readily available and highly sensitive method to ide...

    journal_title:American journal of hematology

    pub_type: 杂志文章

    doi:10.1002/ajh.25773

    authors: Evans LA,Jevremovic D,Nandakumar B,Dispenzieri A,Buadi FK,Dingli D,Lacy MQ,Hayman SR,Kapoor P,Leung N,Fonder A,Hobbs M,Hwa YL,Muchtar E,Warsame R,Kourelis TV,Go R,Russell S,Lust JA,Lin Y,Siddiqui M,Kyle RA,Ger

    更新日期:2020-06-01 00:00:00

  • Low dose cytosine arabinoside in acute myeloid leukemia: remission is not due to differentiation induction.

    abstract::A patient with acute nonlymphoblastic leukemia (FAB M4), showing a near tetraploid chromosome complement on his marrow cells, was treated with low dose cytosine arabinoside and achieved remission. During remission the near tetraploid marrow chromosome complement disappeared and reappeared upon relapse of leukemia. The...

    journal_title:American journal of hematology

    pub_type: 杂志文章

    doi:10.1002/ajh.2830190412

    authors: Pinkerton PH,London B,Cowan DH

    更新日期:1985-08-01 00:00:00

  • Monoclonal B-cell lymphocytosis (MBL) with normal lymphocyte counts is associated with decreased numbers of normal circulating B-cell subsets.

    abstract::Monoclonal B-cell lymphocytosis (MBL) with normal lymphocyte counts is associated with decreased numbers of normal circulating B-cell subsets.Little is known about the distribution of normal lymphoid cells and their subsets in the peripheral blood (PB) of subjects with monoclonal B-cell lymphocytosis (MBL). In our stu...

    journal_title:American journal of hematology

    pub_type: 杂志文章,多中心研究

    doi:10.1002/ajh.23214

    authors: Hauswirth AW,Almeida J,Nieto WG,Teodosio C,Rodriguez-Caballero A,Romero A,López A,Fernandez-Navarro P,Vega T,Perez-Andres M,Valent P,Jäger U,Orfao A,Primary Health Care Group of Salamanca for Study of MBL.

    更新日期:2012-07-01 00:00:00

  • Community experience with bortezomib in patients with multiple myeloma.

    abstract::Community practice experience allows a nonselective care of patient using information derived from a more controlled clinical trial environment. We present our community experience with multiple myeloma patients with advanced age, long disease duration since diagnosis, advanced stage, multiple prior therapies includin...

    journal_title:American journal of hematology

    pub_type: 杂志文章

    doi:10.1002/ajh.20883

    authors: Onitilo AA,Engel J,Olatosi B,Fagbemi S

    更新日期:2007-07-01 00:00:00

  • Vitamin E (alpha-tocopherol) does not inhibit platelet stimulation by oxidized low density lipoprotein in vitro.

    abstract::Platelet-rich plasma were treated with increasing concentrations of vitamin E (alpha-tocopherol). Washed platelets were exposed to oxidized low density lipoprotein (LDL) and examined by aggregometry and electron microscopy. The treatment of washed platelets by oxidized LDL induced morphological signs of activation lik...

    journal_title:American journal of hematology

    pub_type: 杂志文章

    doi:10.1002/(sici)1096-8652(199903)60:3<242::aid-ajh15

    authors: Szuwart T,Dierichs RB,Zhao B

    更新日期:1999-03-01 00:00:00

  • Erythroleukemia: in vitro studies of erythropoiesis.

    abstract::We studied the growth of erythroid burst-forming units (BFU-E) and erythroid colony forming units (CFU-E) from bone marrow and blood in six patients with erythroleukemia. Five patients grew CFU-E, while BFU-E were found in the marrow of two and in the peripheral blood of only one patient. In all cases with colony grow...

    journal_title:American journal of hematology

    pub_type: 杂志文章

    doi:10.1002/ajh.2830050403

    authors: Newcomb MM,Balducci L,Coleman MB,Steinberg MH

    更新日期:1978-01-01 00:00:00

  • The use of ATG abrogates the antileukemic effect of cytomegalovirus reactivation in patients with acute myeloid leukemia receiving grafts from unrelated donors.

    abstract::Several studies provided evidence of a consistent antileukemic effect induced by cytomegalovirus (CMV) replication in acute myeloid leukemia (AML) patients receiving allogeneic hematopoietic stem cell transplantation (HSCT), however the use of antithymocyte globulin (ATG) as graft-versus-host disease prophylaxis, may ...

    journal_title:American journal of hematology

    pub_type: 杂志文章

    doi:10.1002/ajh.23998

    authors: Busca A,Passera R,Pini M,Zallio F,Dellacasa C,Audisio E,Giaccone L,Maffini E,Costa C,Cavallo R,Bruno B

    更新日期:2015-06-01 00:00:00

  • Efficacy and safety of rituximab for systemic lupus erythematosus-associated immune cytopenias: A multicenter retrospective cohort study of 71 adults.

    abstract::The aim of the study was to assess the efficacy and safety of rituximab (RTX) for treating systemic lupus erythematosus (SLE)-associated immune cytopenias. This multicenter retrospective cohort study of adults from French referral centers and networks for adult immune cytopenias and SLE involved patients ≥18 years old...

    journal_title:American journal of hematology

    pub_type: 杂志文章,多中心研究

    doi:10.1002/ajh.24999

    authors: Serris A,Amoura Z,Canouï-Poitrine F,Terrier B,Hachulla E,Costedoat-Chalumeau N,Papo T,Lambotte O,Saadoun D,Hié M,Blanche P,Lioger B,Gottenberg JE,Godeau B,Michel M

    更新日期:2018-03-01 00:00:00

  • The hope and reality of long-acting hemophilia products.

    abstract::Recombinant DNA technology and protein engineering are creating hope that we can address ongoing challenges in hemophilia care such as reducing the costs of therapy, increasing the availability to the developing world, and improving the functional properties of these proteins. Technological advances to improve the hal...

    journal_title:American journal of hematology

    pub_type: 杂志文章,评审

    doi:10.1002/ajh.23146

    authors: Pipe SW

    更新日期:2012-05-01 00:00:00