Stimulation of jejunal mucosal protein synthesis by luminal glucose. Effects with luminal and vascular leucine in fed and fasted rats.

abstract：:We studied intestinal function and hepatic microsomal phase I monooxygenase function in healthy, free-living subjects, aged 19-91 yr. In subjects (n = 114) given a diet including 100 g/day of fat, fecal fat in a 72-h collection did not increase with advancing age. D-Xylose excretion (n = 54) following a 25-g oral load...

journal_title：Gastroenterology

authors： Arora S,Kassarjian Z,Krasinski SD,Croffey B,Kaplan MM,Russell RM

更新日期：1989-06-01 00:00:00

abstract：:In a series of in vitro studies, both the soluble (plasmatic) coagulation system and the cellular (platelet-mediated) aspect of coagulation were shown to be extremely sensitive to relatively minor increases in hydrogen ion concentration. All studies became abnormal at pH 6.8. At pH 6.4, assays of the intrinsic and ext...

journal_title：Gastroenterology

authors： Green FW Jr,Kaplan MM,Curtis LE,Levine PH

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND & AIMS:Postcolonoscopy colorectal cancer (PCCRC) is CRC diagnosed after a colonoscopy in which no cancer was found. A consensus article from the World Endoscopy Organization (WEO) proposed an approach for investigating and categorizing PCCRCs detected within 4 years of a colonoscopy. We aimed to identify cas...

journal_title：Gastroenterology

authors： Anderson R,Burr NE,Valori R

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND & AIMS:Cytotoxic T cells have been suggested to be responsible for lysis of hepatitis B virus (HBV)-infected hepatocytes and control of virus infection. The frequency, kinetics, phenotype, and capacity for clonal expansion of circulating HBV-specific CD8 cells were analyzed directly in patients with acute HB...

journal_title：Gastroenterology

authors： Maini MK,Boni C,Ogg GS,King AS,Reignat S,Lee CK,Larrubia JR,Webster GJ,McMichael AJ,Ferrari C,Williams R,Vergani D,Bertoletti A

更新日期：1999-12-01 00:00:00

abstract：:We tested the hypothesis that the hepatic siderosis that characterizes sporadic porphyria cutanea tarda is due to the presence of HLA-linked hemochromatosis alleles. We studied 21 probands with sporadic porphyria cutanea tarda and 135 of their relatives by determining HLA haplotypes and measuring transferrin saturatio...

journal_title：Gastroenterology

authors： Edwards CQ,Griffen LM,Goldgar DE,Skolnick MH,Kushner JP

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND & AIMS:Liver disease has been associated with cardiovascular disorders, but little is known about the relationship between serum levels of alanine aminotransferase (ALT) and markers of atherogenesis. We investigated the relationship between low-normal and high-normal levels of ALT and an extended panel of ca...

journal_title：Gastroenterology

authors： Siddiqui MS,Sterling RK,Luketic VA,Puri P,Stravitz RT,Bouneva I,Boyett S,Fuchs M,Sargeant C,Warnick GR,Grami S,Sanyal AJ

更新日期：2013-12-01 00:00:00

abstract：:Human intrinsic factor (IF) is found on the surface of parietal cells at the light microscopic level by immunofluorescence, but there is no direct evidence that IF is synthesized in and secreted from this cell. In order to provide this evidence, IF was localized at the ultrastructural level in human stomach, using an ...

journal_title：Gastroenterology

authors： Levine JS,Nakane PK,Allen RH

更新日期：1980-09-01 00:00:00

abstract：BACKGROUND & AIMS:This randomized controlled trial compared variceal band ligation (VBL), propranolol (PPL), and isosorbide-5-mononitrate (ISMN) in the prevention of first esophageal variceal bleed. METHODS:Over a 6-year period, 172 patients with cirrhosis, grade II or III esophageal varices that had never bled, were ...

journal_title：Gastroenterology

authors： Lui HF,Stanley AJ,Forrest EH,Jalan R,Hislop WS,Mills PR,Finlayson ND,Macgilchrist AJ,Hayes PC

更新日期：2002-09-01 00:00:00

abstract：:Fasting hyperbilirubinemia (FHB) has previously been shown to be rapidly reversed by the ingestion of a mixed diet. This study examines the effect of carbohydrate, fat, amino acids, and noncaloric materials on FHB. After an initial fast of 15 to 39 hr, caloric and noncaloric materials were administered by mouth or vei...

journal_title：Gastroenterology

authors： Barrett PV

更新日期：1975-02-01 00:00:00

abstract：:The courses of 38 patients with severe, uncomplicated acute colitis (16 with Crohn's colitis and 22 with ulcerative colitis) were analyzed retrospectively. The patients were placed on total parenteral nutrition and treated concomitantly with corticosteroids, antibiotics (often metronidazole), sulfasalazine, and/or aza...

journal_title：Gastroenterology

authors： Sitzmann JV,Converse RL Jr,Bayless TM

更新日期：1990-12-01 00:00:00

abstract：:Women are underrepresented in gastroenterology. A questionnaire examined the training and career experiences of female members of the Canadian Association for Gastroenterology (CAG) and their male counterparts. A pretested questionnaire was mailed to the 50 female CAG and 100 age-matched male members. Descriptive anal...

journal_title：Gastroenterology

authors： Heathcote J,Cauch-Dudek K,Rhyne D

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND & AIMS:T helper (Th) 17 cells that express the retinoid-related orphan receptor (ROR) γt contribute to the development of colitis in mice, yet are found in normal and inflamed intestine. We investigated their development and functions in intestines of mice. METHODS:We analyzed intestinal Th17 cells in healt...

journal_title：Gastroenterology

authors： Ono Y,Kanai T,Sujino T,Nemoto Y,Kanai Y,Mikami Y,Hayashi A,Matsumoto A,Takaishi H,Ogata H,Matsuoka K,Hisamatsu T,Watanabe M,Hibi T

更新日期：2012-11-01 00:00:00

abstract：:Several compounds, in particular bile acids, undergo enterohepatic circulation (EHC). Limited data are available on the pathophysiologic aspects of this circulation. In the present study we describe a surgical technique in rats that allows a long-term, reversible interruption of the EHC and monitoring of peripheral bl...

journal_title：Gastroenterology

authors： Kuipers F,Havinga R,Bosschieter H,Toorop GP,Hindriks FR,Vonk RJ

更新日期：1985-02-01 00:00:00

abstract：:In order to study the natural history of fundic gland polyposis, 23 patients with familial adenomatosis coli/Gardner's syndrome were examined over a follow-up period ranging from 17 mo to 13 yr (average 6 yr). Examinations included gastric radiography and endoscopy with biopsy. Fundic gland polyps were found in 10 ind...

journal_title：Gastroenterology

authors： Iida M,Yao T,Itoh H,Watanabe H,Kohrogi N,Shigematsu A,Iwashita A,Fujishima M

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND & AIMS:Retinoids inhibit growth and induce differentiation in a variety of pancreatic carcinoma cells. The goal of this study was to examine the molecular mechanisms responsible for retinoid sensitivity. METHODS:Anchorage-independent growth was examined in AR42J, DSL-6A/C1, and Capan-2 cells using a human t...

journal_title：Gastroenterology

authors： Kaiser A,Wolf-Breitinger M,Albers A,Dorbic T,Wittig B,Riecken EO,Rosewicz S

更新日期：1998-10-01 00:00:00

abstract：:Colon motility and myoelectric slow wave activity were compared in 10 patients with progressive systemic sclerosis and 18 controls. Recordings were made in the rectosigmoid and rectum, 25-30 cm and 10-15 cm from the anal margin, respectively, during two 4-min baselines and in response to stepwise distention of the col...

journal_title：Gastroenterology

authors： Whitehead WE,Taitelbaum G,Wigley FM,Schuster MM

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND/AIMS:Ursodeoxycholic acid (UDCA) and colchicine have beneficial effects in primary biliary cirrhosis (PBC). The efficacy of colchicine and UDCA in PBC was compared in a 2-year placebo-controlled study (n = 90). METHODS:Clinical events, laboratory test results, and liver histology were recorded at the beginn...

journal_title：Gastroenterology

authors： Vuoristo M,Färkkilä M,Karvonen AL,Leino R,Lehtola J,Mäkinen J,Mattila J,Friman C,Seppälä K,Tuominen J

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND & AIMS:Chronic stress is associated with visceral hyperalgesia in functional gastrointestinal disorders. We investigated whether corticosterone plays a role in chronic psychological stress-induced visceral hyperalgesia. METHODS:Male rats were subjected to 1-hour water avoidance (WA) stress or subcutaneous c...

journal_title：Gastroenterology

authors： Hong S,Zheng G,Wu X,Snider NT,Owyang C,Wiley JW

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND & AIMS:There are intra- and interobserver variations in endoscopic assessment of ulcerative colitis (UC) and biopsies are often collected for histologic evaluation. We sought to develop a deep neural network system for consistent, objective, and real-time analysis of endoscopic images from patients with UC. ...

journal_title：Gastroenterology

authors： Takenaka K,Ohtsuka K,Fujii T,Negi M,Suzuki K,Shimizu H,Oshima S,Akiyama S,Motobayashi M,Nagahori M,Saito E,Matsuoka K,Watanabe M

更新日期：2020-06-01 00:00:00

abstract：:We studied the effect of chronic aspirin ingestion on gastroduodenal epithelial proliferation by feeding rats aspirin in the drinking water. A control group of rats received plain water. At the end of 4 wk, [3H]-thymidine was given intravenously to label proliferating cells, and the rats were killed 1 h later. Section...

journal_title：Gastroenterology

authors： Eastwood GL,Quimby GF

更新日期：1982-05-01 00:00:00

abstract：:The effect of atropine (100 micrograms/kg/h, i.v.) on plasma cholecystokinin and pancreatic secretion during diversion of bile and pancreatic juice from the intestine was studied in 8 conscious rats equipped with jugular vein, pancreatic, biliary, and duodenal cannulas, and with pyloric ligation and gastric drainage. ...

journal_title：Gastroenterology

authors： Guan D,Ohta H,Tawil T,Spannagel AW,Liddle RA,Green GM

更新日期：1990-02-01 00:00:00

abstract：:Heterogeneity of colonic mucin glycoprotein was examined in rectal mucosal biopsy specimens from a variety of primate species (Saguinus oedipus, n = 18; Macaca mulatta, n = 2; Macaca fascicularis, n = 2; Aotus trivirgatus, n = 2; Saimiri sciureus, n = 2; and Callithrix jacchus, n = 2). After initial separation of radi...

journal_title：Gastroenterology

authors： Podolsky DK,Madara JL,King N,Sehgal P,Moore R,Winter HS

更新日期：1985-01-01 00:00:00

abstract：:Obstruction of the common bile duct can now be relieved by endoscopic electrosurgery. This report describes our experience with 267 patients. In 192 of 222 patients with choledocholithiasis all calculi were evacuated by endoscopic papillotomy (EP). The remaining patients had EP because of papillary stenosis. Complicat...

journal_title：Gastroenterology

authors： Koch H,Rösch W,Schaffner O,Demling L

更新日期：1977-12-01 00:00:00

abstract：:To study the peripheral effect of somatostatin in dogs a tiny Silastic catheter was implanted in an almost terminal branch of the mesenteric artery, providing blood supply to a jejunal segment of 5-10 cm. In 4 dogs one catheter was implanted, perfusing a small bowel segment about 60 cm below the angle of Treitz; in 3 ...

journal_title：Gastroenterology

authors： Hostein J,Janssens J,Vantrappen G,Peeters TL,Vandeweerd M,Leman G

更新日期：1984-11-01 00:00:00

abstract：:Peptic digestion of gluten results in the production of substances having opiatelike activity in bio- and receptor assays. These substances have been termed exorphins. In this study, we determined the effect of gluten, hydrolyzed gluten, and hydrolyzed gluten plus the opiate blocker naloxone on a variety of hormonal p...

journal_title：Gastroenterology

authors： Morley JE,Levine AS,Yamada T,Gebhard RL,Prigge WF,Shafer RB,Goetz FC,Silvis SE

更新日期：1983-06-01 00:00:00

abstract：BACKGROUND & AIMS:Acute-on-chronic liver failure (ACLF) develops in patients with chronic liver disease and has high mortality. Mobilization of bone marrow-derived stem cells with granulocyte colony-stimulating factor (G-CSF) could promote hepatic regeneration. METHODS:Consecutive patients with ACLF were randomly assi...

journal_title：Gastroenterology

authors： Garg V,Garg H,Khan A,Trehanpati N,Kumar A,Sharma BC,Sakhuja P,Sarin SK

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND & AIMS:Infliximab is effective in closing fistulas in patients with Crohn's disease. We examined the effect of infliximab maintenance treatment on hospitalizations, surgeries, and procedures in patients with fistulizing Crohn's disease enrolled in the ACCENT II study. METHODS:After 5 mg/kg infliximab at wee...

journal_title：Gastroenterology

authors： Lichtenstein GR,Yan S,Bala M,Blank M,Sands BE

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:Although it has recently become possible to detect hepatitis C viral antigens in liver biopsy specimens, the frequency and clinical significance of this finding remains uncertain. Therefore, 49 liver biopsy specimens from 35 patients with hepatitis C were studied to make these assessments. METHODS:Hepatitis...

journal_title：Gastroenterology

authors： Di Bisceglie AM,Hoofnagle JH,Krawczynski K

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND & AIMS:Prediction of relapse of inflammatory bowel disease has important implications for therapeutic strategies. We assessed whether measurement of intestinal permeability and inflammation could predict relapse of inflammatory bowel disease (IBD). METHODS:Forty-three patients with Crohn's disease (CD) and ...

journal_title：Gastroenterology

authors： Tibble JA,Sigthorsson G,Bridger S,Fagerhol MK,Bjarnason I

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND & AIMS:Aberrant activation of β-catenin and Yes-associated protein 1 (Yap1) signaling pathways have been associated with the development of multiple tumor types. Yap functions as a transcriptional coactivator by interacting with TEA domain DNA binding proteins. We investigated the interactions among these pa...

journal_title：Gastroenterology

authors： Tao J,Calvisi DF,Ranganathan S,Cigliano A,Zhou L,Singh S,Jiang L,Fan B,Terracciano L,Armeanu-Ebinger S,Ribback S,Dombrowski F,Evert M,Chen X,Monga SPS

更新日期：2014-09-01 00:00:00