Abstract:
:In 1842 Charles Darwin claimed that vertical growth on a subsiding foundation caused fringing reefs to transform into barrier reefs then atolls. Yet historically no transition between reef types has been discovered and they are widely considered to develop independently from antecedent foundations during glacio-eustatic sea-level rise. Here we reconstruct reef development from cores recovered by IODP Expedition 310 to Tahiti, and show that a fringing reef retreated upslope during postglacial sea-level rise and transformed into a barrier reef when it encountered a Pleistocene reef-flat platform. The reef became stranded on the platform edge, creating a lagoon that isolated it from coastal sediment and facilitated a switch to a faster-growing coral assemblage dominated by acroporids. The switch increased the reef's accretion rate, allowing it to keep pace with rising sea level, and transform into a barrier reef. This retreat mechanism not only links Darwin's reef types, but explains the re-occupation of reefs during Pleistocene glacio-eustacy.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Blanchon P,Granados-Corea M,Abbey E,Braga JC,Braithwaite C,Kennedy DM,Spencer T,Webster JM,Woodroffe CDdoi
10.1038/srep04997subject
Has Abstractpub_date
2014-05-21 00:00:00pages
4997issn
2045-2322pii
srep04997journal_volume
4pub_type
杂志文章abstract::Plumbagin, an anti-cancer agent, is toxic to cells of multiple species. We investigated if plumbagin targets conserved biochemical processes. Plumbagin induced DNA damage and apoptosis in cells of diverse mutational background with comparable potency. A 3-5 fold increase in intracellular oxygen radicals occurred in re...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-19261-w
更新日期:2018-01-18 00:00:00
abstract:ABSRACT:Vegetation cover is crucial to controlling aeolian erosion but highly efficient vegetation is critical. How this efficiency is influenced by vegetation response to airflow is not clear. Here we evaluate the responses of Cosmos bipinnatus and Ligustrum lucidum Ait to a range of wind speeds in a wind tunnel. For ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-13084-x
更新日期:2017-10-09 00:00:00
abstract::Single nucleotide polymorphisms (SNPs) in the 3'-untranslated regions targeted by putative mircoRNA can change its binding strength, affecting the susceptibility and prognosis of cancer. We aimed to investigate the associations between SNPs within miR-148a binding sites and gastric cancer (GC) risk and prognosis. Usin...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep07080
更新日期:2014-11-17 00:00:00
abstract::Phelan McDermid Syndrome (PMDS) is a genetic disorder characterized by features of Autism spectrum disorders. Similar to reports of Zn deficiency in autistic children, we have previously reported high incidence of Zn deficiency in PMDS. However, the underlying mechanisms are currently not well understood. Here, using ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep45190
更新日期:2017-03-27 00:00:00
abstract::Isolated lung perfusion (ILP) is an ideal model to study treatment effects on a variety of pathologies. As published research mostly relies on rejected donor lungs or animal organs, this study investigates the use of surgically resected human lobes as an alternative and novel model for personalized experimental resear...
journal_title:Scientific reports
pub_type: 临床试验,杂志文章
doi:10.1038/s41598-019-48719-8
更新日期:2019-08-21 00:00:00
abstract::First identified in The Netherlands in 2004, human coronavirus NL63 (HCoV-NL63) was found to cause worldwide infections. Patients infected by HCoV-NL63 are typically young children with upper and lower respiratory tract infection, presenting with symptoms including croup, bronchiolitis, and pneumonia. Unfortunately, t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep22677
更新日期:2016-03-07 00:00:00
abstract::Clobetasol propionate (CLO) is a potent glucocorticoid used to treat inflammation-based skin, scalp, and hair disorders. In such conditions, hair follicles (HF) are not only the target site but can also act as drug reservoirs when certain formulations are topically applied. Recently, we have demonstrated nanostructure...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-56760-w
更新日期:2020-01-13 00:00:00
abstract::H5N1 highly pathogenic avian influenza virus (HPAIV) poses a huge threat to public health and the global economy. These viruses cause systemic infection in poultry and accidental human infection leads to severe pneumonia, associated with high mortality rates. The hemagglutinin (HA) of H5N1 HPAIV possesses multiple bas...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-74604-w
更新日期:2020-10-22 00:00:00
abstract::The striatum plays important motor, associative and cognitive roles in brain functions. However, the rodent dorsolateral (the primate putamen) and dorsomedial (the primate caudate nucleus) striatum are not anatomically separated, making it difficult to distinguish their functions. By contrast, anatomical separation ex...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep35809
更新日期:2016-11-02 00:00:00
abstract::Nitrogen fixation is essential for the synthesis of many important chemicals (e.g., fertilizers, explosives) and basic building blocks for all forms of life (e.g., nucleotides for DNA and RNA, amino acids for proteins). However, direct nitrogen fixation is challenging as nitrogen (N₂) does not easily react with other ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep02260
更新日期:2013-01-01 00:00:00
abstract::An available pathway to prepare the ionized covalent organic nanosheets (iCONs) has been proposed by a metal-assisted aqueous-phase exfoliation route from covalent organic frameworks. The soluble and belt-shaped iCONs could immobilize a large quantity of proteins (2.73 mg/mg, BSA/iCONs) and hence serve as transporters...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-23744-1
更新日期:2018-04-03 00:00:00
abstract::An increased breast cancer risk during adulthood has been linked to estrogen exposure during fetal life. However, the impossibility of removing estrogens from the feto-maternal unit has hindered the testing of estrogen's direct effect on mammary gland organogenesis. To overcome this limitation, we developed an ex vivo...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep40806
更新日期:2017-01-19 00:00:00
abstract::Previous work has shown that human vision performs spatial integration of luminance contrast energy, where signals are squared and summed (with internal noise) over area at detection threshold. We tested that model here in an experiment using arrays of micro-pattern textures that varied in overall stimulus area and sp...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep29764
更新日期:2016-07-27 00:00:00
abstract::Compromised activity of the DNA repair enzymes may raise the risk of a number of cancers. We analyzed polymorphisms in the Xeroderma Pigmentosum, Complementation Group C (XPC) gene for their correlation with urinary bladder cancer. Ala499Val and Lys939Gln polymorphisms were genotyped in 234 urinary bladder cancer case...
journal_title:Scientific reports
pub_type: 杂志文章,meta分析
doi:10.1038/srep27018
更新日期:2016-06-01 00:00:00
abstract::G-quadruplexes (G4s) are nucleic acids secondary structures, epigenetic regulators in cells and viruses. In herpes simplex virus 1 (HSV-1)-infected cells, G4s are massively present during viral replication. We here aimed at investigating the possibility to target the HSV-1 G4s by a core extended naphtalene diimide (c-...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-02667-3
更新日期:2017-05-24 00:00:00
abstract::Gene expression profiles reflect the biologically diverse activities of cells under specific cell environments. Using the transcriptional response of cultured cells to blood composition, we developed a litmus gene assay to discriminate blood samples reflecting different sample qualities or disease conditions. This cel...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-17293-2
更新日期:2017-12-04 00:00:00
abstract::A new fluorine-substituted ligand, compound 1 (CB251), with a very high affinity (Ki = 0.27 ± 0.09 nM) and selectivity for the 18-kDa translocator protein (TSPO), is presented as an attractive biomarker for the diagnosis of neuroinflammation, neurodegeneration and tumour progression. To test compound 1 as a TSPO PET i...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep20422
更新日期:2016-02-08 00:00:00
abstract::Fungi play a key role in the functioning of soil in terrestrial ecosystems, and in particular in the remediation of degraded soils. The contribution of fungi to carbon and nutrient cycles, along with their capability to mobilise soil trace elements, is well-known. However, the importance of life history strategy for t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-63194-2
更新日期:2020-04-15 00:00:00
abstract::Ubiquitylation is a protein modification implicated in several cellular processes. This process is reversible by the action of deubiquinating enzymes (DUBs). USP45 is a ubiquitin specific protease about which little is known, aside from roles in DNA damage repair and differentiation of the vertebrate retina. Here, by ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-32685-8
更新日期:2018-09-26 00:00:00
abstract::Intestinal microbiome changes that occur in HIV positive individuals on different antiretroviral therapy (ART) regimens are important to understand, as they are potentially linked with chronic inflammation and microbiome-linked comorbidities that occur at increased incidence in this population. We conducted a cross-se...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep43741
更新日期:2017-03-06 00:00:00
abstract::To assess the prevalence and associated factors of glaucoma in a Russian population. The population-based Ural Eye and Medical Study included 5899 (mean age 59.0 ± 10.7 years; range 40-94 years). Glaucomatous optic neuropathy was diagnosed using International Society of Geographical and Epidemiological Ophthalmology (...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-77344-z
更新日期:2020-11-20 00:00:00
abstract::A singular adaptive phenotype of a parthenogenetic insect species (Acyrthosiphon pisum) was selected in cold conditions and is characterized by a remarkable apparition of a greenish colour. The aphid pigments involve carotenoid genes well defined in chloroplasts and cyanobacteria and amazingly present in the aphid gen...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep00579
更新日期:2012-01-01 00:00:00
abstract::An accurate and efficient solution of the radiative transport equation is proposed for modeling the propagation of photons in the three-dimensional anisotropically scattering half-space medium. The exact refractive index mismatched boundary condition is considered and arbitrary rotationally invariant scattering functi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep02018
更新日期:2013-01-01 00:00:00
abstract::Pertuzumab is an antihuman HER2 antibody developed for HER2 positive breast cancer. Glycosylation profiles are always the important issue for antibody based therapy. Previous findings have suggested the impact of glycosylation profiles on the function of antibodies, like pharmacodynamics, antibody-dependent cellular c...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep46347
更新日期:2017-04-11 00:00:00
abstract::Corals build their skeletons using extracellular calcifying fluid located in the tissue-skeleton interface. However, the mechanism by which corals control the transport of calcium and other ions from seawater and the mechanism of constant alkalization of calcifying fluid are largely unknown. To address these questions...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep40324
更新日期:2017-01-18 00:00:00
abstract::Nisin inhibits bacterial growth by generating pores in cell membrane and interrupting cell-wall biosynthesis through specific lipid II interaction. However, the role of the hinge region and C-terminus residues of the peptide in antibacterial action of nisin is largely unknown. Here, using molecular dynamics simulation...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep37908
更新日期:2016-11-29 00:00:00
abstract::The experimental approach for the study of cardiometabolic disorders requires the use of animal models fed with commercial diets whose composition differs notably, even between diets used for control groups. While chow diets are usually made of agricultural by-products, purified low-fat diets (LF) contain a higher per...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-59674-0
更新日期:2020-02-19 00:00:00
abstract::Two polar vessels, Akademik Shokalskiy and Xuelong, were trapped by thick sea ice in the Antarctic coastal region just to the west of 144°E and between 66.5°S and 67°S in late December 2013. This event demonstrated the rapid establishment of extreme Antarctic sea ice conditions on synoptic time scales. The event was a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep05317
更新日期:2014-06-17 00:00:00
abstract::Surfactants during routine washing have a tremendous effect on lipid loss from hair. This study aims to understand the loss of lipids from hair upon contact with surfactants and develop a way to prevent the lipid loss. The change in lipid levels depends on the relative hydrophobicity of the lipid. We herein propose th...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-46370-x
更新日期:2019-07-08 00:00:00
abstract::Understanding the transmission patterns of African swine fever (ASF) among wild boar (Sus scrofa) is an issue of major interest, especially in the wake of the current ASF epidemic. Given the high stability of ASF-virus, there is concern about scavengers spreading infectious carcass material in the environment. Here, w...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-47623-5
更新日期:2019-08-07 00:00:00