Predictive value of circulating miR-328 and miR-134 for acute myocardial infarction.

abstract：:The uptake of glucose and gluconate is under inductive control in Pseudomonas putida. Glucose, gluconate, and 2-ketogluconate were each good nutritional inducers of these transport abilities. Glucose and gluconate uptake obeyed saturation kinetics: the apparent Km for glucose was 6 mM and that for gluconate was 0.5 mM...

journal_title：Molecular and cellular biochemistry

authors： Vicente M,Pedro MA,Torrontegui G,Cánovas JL

更新日期：1975-04-30 00:00:00

abstract：:Progression of prostate cancer is facilitated by growth factors that activate critical signaling cascades thereby promote prostate cancer cell growth, survival, and migration. To investigate the effect of quercetin on insulin-like growth factor signaling and apoptosis in androgen independent prostate cancer cells (PC-...

journal_title：Molecular and cellular biochemistry

authors： Senthilkumar K,Elumalai P,Arunkumar R,Banudevi S,Gunadharini ND,Sharmila G,Selvakumar K,Arunakaran J

更新日期：2010-11-01 00:00:00

abstract：:The mainstream explanation of enzyme catalysis relies on the assumption that enzymes can utilize the binding energy. The author suggest that (i) an enzyme with excess free energy first gives a group from its active site into the final place of the bound reactant (substrate) in order to break the first initial chemical...

journal_title：Molecular and cellular biochemistry

authors： Foigel AG

更新日期：2011-06-01 00:00:00

abstract：:The involvement of a hypocalcemic hormone calcitonin (CT) in the expression of hepatic Ca(2+)-binding protein regucalcin mRNA was investigated. The change of regucalcin mRNA levels was analyzed by Northern blotting using liver regucalcin complementary DNA (0.9 kb). A single oral administration of calcium chloride (100...

journal_title：Molecular and cellular biochemistry

authors： Yamaguchi M,Kanayama Y,Shimokawa N

更新日期：1994-07-13 00:00:00

abstract：:Ran-binding protein in microtubule-organizing center (RanBPM) has been reported to interact with the neurotrophin receptors p75NTR and TrkA, meanwhile p75NTR and TrkA can also interact with TRAF6. Whether RanBPM interacts directly with TRAF6 has not yet been established. In this study, using a yeast two-hybrid system ...

journal_title：Molecular and cellular biochemistry

authors： Wang L,Fu C,Cui Y,Xie Y,Yuan Y,Wang X,Chen H,Huang BR

更新日期：2012-01-01 00:00:00

abstract：:The PPAR-gamma receptor agonists, as a relatively new and perhaps still not very widely used class of antidiabetic agent in the Caribbean and particularly the Trinidadian context, possess pharmacologic properties that certainly have been shown to have impact on many of the inflammatory, metabolic, biochemical and stru...

journal_title：Molecular and cellular biochemistry

authors： Smith SI

更新日期：2004-08-01 00:00:00

abstract：:Pig coronary artery cultured smooth muscle cells were skinned using saponin. In the presence of an ATP-regenerating system and oxalate, the skinned cells showed an ATP-dependent azide insensitive Ca(2+)-uptake which increased linearly with time for > 1 h. The Ca(2+)-uptake occurred with Km values of 0.20 +/- 0.03 micr...

journal_title：Molecular and cellular biochemistry

authors： Elmoselhi AB,Blennerhassett M,Samson SE,Grover AK

更新日期：1995-10-18 00:00:00

abstract：:Glomerular mesangial cells play an important role in the development of glomerulosclerosis. Mesangial cell apoptosis has been shown to be involved in different stages of development of glomerulonephritis. The aim of the present study was to evaluate the effect of inhibition of serine/threonine phosphatases by okadaic ...

journal_title：Molecular and cellular biochemistry

authors： Parameswaran N,Spielman WS,Brooks DP,Nambi P

更新日期：2004-05-01 00:00:00

abstract：:The aim of the present study was to investigate whether lipid metabolism in the nuclei is affected by changes in the metabolism of free fatty acids in the liver. The experiments were carried out on 3 groups of rats: 1 - control-male, 2 - female, and 3 - male, treated with bezafibrate (a peroxisome proliferator). The r...

journal_title：Molecular and cellular biochemistry

authors： Górski J,Zendzian-Piotrowska M,Wolfrum C,Nawrocki A,Spener F

更新日期：2000-11-01 00:00:00

abstract：:The natriuretic peptide receptor-A (NPR-A) is involved in blood pressure and body fluid regulation in order to help maintain cardiovascular homeostasis. It has been shown that these biological effects are mediated through the natriuretic peptide family of hormones, which bind NPR-A according to the rank order ANP>BNP>...

journal_title：Molecular and cellular biochemistry

authors： Marquis M,Fenrick R,Pedro L,Bouvier M,De Léan A

更新日期：1999-04-01 00:00:00

abstract：:S-glutathionylation, the formation of mixed disulfides of glutathione with cysteine residues of proteins, is a broadly observed physiological modification that occurs in response to oxidative stress. Since cysteine residues are particularly susceptible to oxidative modification by reactive oxygen species, S-glutathion...

journal_title：Molecular and cellular biochemistry

authors： Leonberg AK,Chai YC

更新日期：2007-10-01 00:00:00

abstract：:Computer retrieval in a database, comprising 7,225 muscle cases, revealed that mitochondrial myopathies do not occur more frequently in inflammatory myopathies (3.74%) than in the whole series (3.69%). A more detailed study of inclusion body myositis (IBM), however, showed that severe mitochondrial alterations were ap...

journal_title：Molecular and cellular biochemistry

authors： Schröder JM,Molnar M

更新日期：1997-09-01 00:00:00

abstract：:Tripeptide aminopeptidase (EC 3.4.11.4) was purified from bovine dental follicles by a series of chromatographies. Purified enzyme had a specific activity of 59.5 units per mg protein with L-prolyl-glycylglycine as substrate. The pH optimum was 8.0. The purified native enzyme had a Mr of 230,000 and was shown to be a ...

journal_title：Molecular and cellular biochemistry

authors： Hiraoka BY,Harada M

更新日期：1993-12-08 00:00:00

abstract：:Carbohydrate has been removed from a number of glycoproteins without major effect on the structure or enzyme activity of the protein. Thus carbohydrate has been suggested to underly a non-primary function for proteins, such as in relatively non-specific interactions with other carbohydrates or macromolecules, stabiliz...

journal_title：Molecular and cellular biochemistry

authors： West CM

更新日期：1986-11-01 00:00:00

abstract：:Transforming growth factor-β1 (TGF-β1) has been thought to play a major role during cardiac fibrosis in the development of diabetic cardiomyopathy, and cardiac fibrosis mainly as a result of an increase of collagen type III occurs in the human hearts with diabetes. Thrombospondin-1 (TSP-1) has been reported to activat...

journal_title：Molecular and cellular biochemistry

authors： Tang M,Zhou F,Zhang W,Guo Z,Shang Y,Lu H,Lu R,Zhang Y,Chen Y,Zhong M

更新日期：2011-01-01 00:00:00

abstract：:Young female Zucker fa/fa rats of 370-430 g were implanted with osmotic minipumps releasing 3.5 micromol/day-kg of estrone oleate in liposomes (Merlin-2) into the bloodstream for up to 14 days. Merlin-2 induced a sustained loss of appetite, and a decrease in body weight of 3.5%, which contrasts with the 8.2% increase ...

journal_title：Molecular and cellular biochemistry

authors： Adán C,Grasa MM,Cabot C,Esteve M,Vilà R,Masanés R,Estruch J,Fernández-López JA,Remesar X,Alemany M

更新日期：1999-07-01 00:00:00

abstract：:Serratia marcescens utilizes two types of quorum-sensing signal molecules: N-acyl homoserine lactones and furanosyl borate diester (AI-2). S-adenosylmethionine synthetase (METK), S-adenosylhomocysteine nucleosidase (PFS), and S-ribosylhomocysteinase (LUXS) are three key enzymes in the biosynthetic pathway leading to A...

journal_title：Molecular and cellular biochemistry

authors： Zhu H,Shen YL,Wei DZ,Zhu JW

更新日期：2008-08-01 00:00:00

abstract：:Enzymes have proven to be sensitive and versatile labels for immunochemical assays. The sensitivity of an enzyme label stems from its extraordinary catalytic power which in turn provides a great amplification of signals. Its versatility, however, stems from the fact that enzyme activity can be modulated by a number of...

journal_title：Molecular and cellular biochemistry

authors： Ngo TT,Lenhoff HM

更新日期：1982-04-16 00:00:00

abstract：:Lipoprotein-X (Lp-X) is found in the plasma of patients with familial lecithin: cholesterol acyltransferase (LCAT) deficiency syndromes. The majority of the patients with this disorder develop progressive glomerulosclerosis. In this study, the effect of Lp-X on lipid metabolism in perfused rat kidney was investigated....

journal_title：Molecular and cellular biochemistry

authors： O K,Ly M,Fang DZ,Frohlich J,Choy PC

更新日期：1997-08-01 00:00:00

abstract：:Modification of 60S ribosomal subunits from rat liver with dimethylmaleic anhydride (60 mumols/ml) is accompanied by release of 35% of the protein. The acidic ribosomal proteins, as well as 9 basic proteins, are selectively liberated from the ribosomal subunits. Reconstitution of the protein-deficient particles with t...

journal_title：Molecular and cellular biochemistry

authors： Garrido S,González PJ,Palacián E,Hernández F

更新日期：1990-02-09 00:00:00

abstract：:Salidroside, a phenol glycoside of plant origin, has been documented to possess a broad spectrum of pharmacological properties, including protective effects against neuronal death induced by different insults. To provide further insights into the neuroprotective functions peculiar to salidroside, this study used prima...

journal_title：Molecular and cellular biochemistry

authors： Zhang S,Chen X,Yang Y,Zhou X,Liu J,Ding F

更新日期：2011-08-01 00:00:00

abstract：:Two forms of the regulatory subunit of the type II cAMP-dependent protein kinase (RII55 and RII52) were identified from bovine heart by gel electrophoretic behaviour. After autophosphorylation the RII55 isoform migrated more slowly (RII55/57) while the migration of RII52 isoform did not shift. Both isoforms showed dif...

journal_title：Molecular and cellular biochemistry

authors： González-Nicolás J,Jiménez JS,Moreno FJ

更新日期：1990-07-17 00:00:00

abstract：:We propose a simple mechanism which enables decrease of the free pool of channelled metabolite in static spatial channelling, when the concentration of the enzyme consuming the channelled metabolite is greater than the concentration of the enzyme producing this metabolite. Spatial channelling occurs between two enzyme...

journal_title：Molecular and cellular biochemistry

authors： Korzeniewski B,Quant PA

更新日期：1997-04-01 00:00:00

abstract：:Endothelial cell nitric oxide synthase (NOS) is known to have a N-myristoylation consensus sequence. Such a consensus sequence is not evident in the macrophage, smooth muscle and neuronal NOS. A functional role for this N-terminal myristoylation is not clear yet. In the present study, we examined the effect of N-termi...

journal_title：Molecular and cellular biochemistry

authors： Sakoda T,Hirata K,Kuroda R,Miki N,Suematsu M,Kawashima S,Yokoyama M

更新日期：1995-11-22 00:00:00

abstract：:Interleukin 8 (IL-8) is a chemoattractant associated with ovulation in the mammalian ovary. This chemokine is also involved in the recruitment and activation of neutrophils. Using bovine tissue, we examined the possible role of IL-8 in steroid production by theca cells of the large ovarian follicles. IL-8 promoted pro...

journal_title：Molecular and cellular biochemistry

authors： Shimizu T,Imamura E,Magata F,Murayama C,Miyamoto A

更新日期：2013-02-01 00:00:00

abstract：:Primary cultures of skeletal muscle cells secrete plasminogen activator (PA) activity to the conditioning medium and display membrane-bound PA. Growth of these cells in culture in presence of 10(-7) M dexamethasone resulted in a marked reduction of the membranal and secreted PA activity. The hormone also reduced cytos...

journal_title：Molecular and cellular biochemistry

authors： Mayer M,Finci Z,Chaouat M,Sasson S

更新日期：1986-02-01 00:00:00

abstract：:Nickel compounds are carcinogenic and induce malignant transformation of cultured cells. Since nickel has low mutagenic potential, it may act predominantly through epigenetic mechanisms, including down-regulation of tumor suppressor genes. FHIT is a tumor suppressor gene whose expression is frequently reduced or lost ...

journal_title：Molecular and cellular biochemistry

authors： Kowara R,Salnikow K,Diwan BA,Bare RM,Waalkes MP,Kasprzak KS

更新日期：2004-01-01 00:00:00

abstract：:Hydrocortisone hemisuccinate within 4 hours after in vivo administration produced an increase in precursor incoporation into rat thymus RNA and proteins in the whole animal. From these results, together with information obtained from measurements of the tyrosine aminotransferase activity and the action of mitomycin C ...

journal_title：Molecular and cellular biochemistry

authors： Abraham AD

更新日期：1975-12-31 00:00:00

abstract：:Ionizing radiation (IR) treatment results in activation of several DNA damage response molecules, such as ataxia telangiectasia, mutated (ATM), and DNA-dependent protein kinase (DNAPK) in mammals that are increasingly recognized for their potential roles in the sensing of DNA damage and initiating the subsequent prote...

journal_title：Molecular and cellular biochemistry

authors： Dhariwala FA,Narang H,Krishna M

更新日期：2012-04-01 00:00:00

abstract：:Deficient wound healing is a common multifactorial complication in diabetic patients, but the cellular and molecular mechanisms involved are poorly defined. In the present study, we analyzed the effects of hyperglycemia on integrins expression in rat dermal fibroblasts and addressed its role in cell adhesion and migra...

journal_title：Molecular and cellular biochemistry

authors： Almeida ME,Monteiro KS,Kato EE,Sampaio SC,Braga TT,Câmara NO,Lamers ML,Santos MF

更新日期：2016-10-01 00:00:00