L-tyrosine: 2-oxoglutarate aminotransferase induction by hydrocortisone in the thymus of the white rat.

abstract：:The epithelial cells of the human intestine exhibit a cholinesterase activity which is restricted to the apex of the villi. This activity displays a maximum in the colon and a minimum in the jejunum. Contrary to most of the studied vertebrates, the human cells present both acetylcholinesterase and butyrylcholinesteras...

journal_title：Molecular and cellular biochemistry

authors： Sine JP,Ferrand R,Cloarec D,Lehur PA,Colas B

更新日期：1991-12-11 00:00:00

abstract：:Ionizing radiation (IR) treatment results in activation of several DNA damage response molecules, such as ataxia telangiectasia, mutated (ATM), and DNA-dependent protein kinase (DNAPK) in mammals that are increasingly recognized for their potential roles in the sensing of DNA damage and initiating the subsequent prote...

journal_title：Molecular and cellular biochemistry

authors： Dhariwala FA,Narang H,Krishna M

更新日期：2012-04-01 00:00:00

abstract：:We report the isolation of a full length cDNA from cardiac muscle that encodes a approximately 73 kDa calcium/calmodulin (CaM) dependent kinase IIbeta isoform (CaMKIIbeta(C)) that was generated by alternative splicing of the CaMKIIbeta gene. Antipeptide antibodies raised to specific regions of the kinase identified a ...

journal_title：Molecular and cellular biochemistry

authors： Singh P,Leddy JJ,Chatzis GJ,Salih M,Tuana BS

更新日期：2005-02-01 00:00:00

abstract：:The effect of peritoneal dialysis (PD) with high-glucose dialysis fluid on the VEGF family, tristetraprolin (TTP), angiogenesis and lymphangiogenesis was investigated. Forty male SD rats were randomised into five groups: normal group, sham operation group, uraemia group, PD 2-week group and PD4-week group. After 4 wee...

journal_title：Molecular and cellular biochemistry

authors： Xiao J,Gao H,Jin Y,Zhao Z,Guo J,Liu Z,Zhao Z

更新日期：2014-07-01 00:00:00

abstract：:The oxygenase domain of the inducible nitric oxide synthase, Delta65 iNOSox is a dimer that binds heme, L-Arginine (L-Arg), and tetrahydrobiopterin (H(4)B) and is the site for NO synthesis. The role of H(4)B in iNOS structure-function is complex and its exact structural role is presently unknown. The present paper pro...

journal_title：Molecular and cellular biochemistry

authors： Sengupta R,Sahoo R,Ray SS,Dutta T,Dasgupta A,Ghosh S

更新日期：2006-03-01 00:00:00

abstract：:The function of the uterine smooth muscle in gestation and parturition is affected by a variety of hormones and biomolecules, some of which alter the intracellular levels of cAMP and Ca2+. Since the activity of smooth muscle MLCK has been shown to be modulated by phosphorylation, the effect of this modification of pre...

journal_title：Molecular and cellular biochemistry

authors： Pato MD,Kerc E,Lye SJ

更新日期：1995-08-01 00:00:00

abstract：:To investigate insulin action in muscle and adipose tissue in hepatic cirrhosis, a recently described animal model was used. Dimethylnitrosamine administration induced histologically proven cirrhosis. Contrary to expectation, muscle strips from cirrhotic rats displayed increased insulin sensitivity both with respect t...

journal_title：Molecular and cellular biochemistry

authors： Chowdhury SA,Taylor R

更新日期：1989-08-15 00:00:00

abstract：:In this work we investigated the effects of retinoic acid (RA) in Sertoli cells. Sertoli cells isolated from 15-day-old Wistar rats were previously cultured for 48 h and then treated with RA for 24 h. RA at high doses (1-10 microM) increased TBARS levels and induced a decrease in cell viability. At low doses (0.1-100 ...

journal_title：Molecular and cellular biochemistry

authors： Conte da Frota ML Jr,Gomes da Silva E,Behr GA,Roberto de Oliveira M,Dal-Pizzol F,Klamt F,Moreira JC

更新日期：2006-04-01 00:00:00

abstract：:Insulin elicits its divergent metabolic and mitogenic effects by binding to its specific receptor, which belongs to the family of receptor tyrosine kinases. The activated insulin receptor phosphorylates the intracellular substrate IRS-1, which then binds various signalling molecules that contain SRC homology 2 domains...

journal_title：Molecular and cellular biochemistry

authors： Ogawa W,Matozaki T,Kasuga M

更新日期：1998-05-01 00:00:00

abstract：:Overexpressed cysteine-rich protein 61 (Cyr61) is believed to enhance osteosarcoma (OS) cell metastasis, but the mechanism of Cyr61 overexpression in OS is not clear so far. In this study 33 OS samples were analyzed by immunostaining and focused on two parts: the correlation between overexpression of Cyr61 and OS meta...

journal_title：Molecular and cellular biochemistry

authors： Chen J,Song Y,Yang J,Gong L,Zhao P,Zhang Y,Su H

更新日期：2013-12-01 00:00:00

abstract：:Retinal pigment epithelium (RPE) exerts critical roles in the maintenance of the normal functions of the retina, whereas RPE dysfunction can induce retina neovascularization. p75 neurotrophin receptor (p75(NTR)) has been shown to play essential roles in angiogenesis. However, the function of p75(NTR) in the RPE remain...

journal_title：Molecular and cellular biochemistry

authors： Zhang J,Zhao J,Bai Y,Huang L,Yu W,Li X

更新日期：2015-01-01 00:00:00

abstract：:Our study evaluated the relationship between the endogenous production of prostacyclin and the antiarrhythmic effect of ischemic preconditioning against ischemic and reperfusion-induced tachyarrhythmia. Langendorff perfused rat hearts underwent 30 min regional ischemia with reperfusion. Preconditioning was induced by ...

journal_title：Molecular and cellular biochemistry

authors： Arad M,Oxman T,Leor R,Rabinowitz B

更新日期：1996-07-01 00:00:00

abstract：:Advanced glycation end products (AGEs) are formed from the non-enzymatic glycation reaction of reducing sugars or their metabolites with the free amino groups of several biomolecules and are known to play pathophysiological roles in various inflammatory diseases. In an earlier study, it was suggested that tumor necros...

journal_title：Molecular and cellular biochemistry

authors： Watanabe M,Toyomura T,Wake H,Liu K,Teshigawara K,Takahashi H,Nishibori M,Mori S

更新日期：2017-10-01 00:00:00

abstract：:Total cellular creatine content is an important bioenergetic parameter in skeletal muscle. To understand its regulation we investigated creatine transport and accumulation in the G8 cultured skeletal myoblast line. Like other cell types, these contain a creatine transporter, whose activity, measured using a radiolabel...

journal_title：Molecular and cellular biochemistry

authors： Odoom JE,Kemp GJ,Radda GK

更新日期：1996-05-24 00:00:00

abstract：:Our interest in the role of sulfhydryl groups (SH) in regulating or altering transport across biological membranes has focused on the significance of a critical SH group associated with the Ca2+-release protein from skeletal muscle sarcoplasmic reticulum (SR). We have shown that binding of heavy metals to this group o...

journal_title：Molecular and cellular biochemistry

authors： Abramson JJ,Salama G

更新日期：1988-07-01 00:00:00

abstract：:Using rat liver mitochondria, as model systems, we have examined the ability of the natural compound and the food-flavoring agent, vanillin to protect membranes against oxidative damage induced by photosensitization at concentrations normally used in food preparations. Vanillin, at a concentration of 2.5 mmol/L, has a...

journal_title：Molecular and cellular biochemistry

authors： Kamat JP,Ghosh A,Devasagayam TP

更新日期：2000-06-01 00:00:00

abstract：:MicroRNAs play critical roles in the development and progression of non-small cell lung cancer (NSCLC). miR-96 acts as an oncogene in some malignancies, while its role in NSCLC is unclear. Here, we validated that miR-96 was significantly increased in both human NSCLC tissues and cell lines. Inhibition of miR-96 expres...

journal_title：Molecular and cellular biochemistry

authors： Guo H,Li Q,Li W,Zheng T,Zhao S,Liu Z

更新日期：2014-05-01 00:00:00

abstract：:Antimycin A (AMA) inhibits succinate oxidase, NADH oxidase, and mitochondrial electron transport chain between cytochrome b and c. We recently demonstrated that AMA inhibited the growth of Calu-6 lung cancer cells through apoptosis. Here, we investigated the effects of AMA and/or MAPK inhibitors on Calu-6 lung cancer ...

journal_title：Molecular and cellular biochemistry

authors： Han YH,Park WH

更新日期：2010-01-01 00:00:00

abstract：:Frequenin is a member of the neuronal Ca(2+) sensor protein family, implicated in being the modulator of the neurotransmitter release, potassium channels, phosphatidylinositol signaling pathway and the Ca(2+)-dependent exocytosis of dense-core granules in the PC12 cells. Frequenin exhibits these biological activities ...

journal_title：Molecular and cellular biochemistry

authors： Fik-Rymarkiewicz E,Duda T,Sharma RK

更新日期：2006-10-01 00:00:00

abstract：:Ovarian cancer is one of the greatest causes of cancer death in women. The association of TMEM49 and ovarian cancer is poorly defined. Here, we reported that TMEM49 was significantly increased in ovarian tumor tissues compared to ovarian normal tissues. Furthermore, down-regulation of TMEM49 through RNA interference i...

journal_title：Molecular and cellular biochemistry

authors： Zheng L,Chen L,Zhang X,Zhan J,Chen J

更新日期：2016-05-01 00:00:00

abstract：:Acrolein is a highly reactive alpha, beta-unsaturated aldehyde, and a product of lipid peroxidation reactions. Acrolein is also an environmental pollutant and a key component of cigarette smoke, and has been implicated in multiple respiratory diseases. Lung tissue is a primary target for acrolein toxicity in smokers a...

journal_title：Molecular and cellular biochemistry

authors： Sarkar P,Hayes BE

更新日期：2007-07-01 00:00:00

abstract：:Growth hormone (GH) has been reported to be useful to treat heart failure. To elucidate whether GH has direct beneficial effects on the heart, we examined effects of GH on oxidative stress-induced apoptosis in cardiac myocytes. TUNEL staining and DNA ladder analysis revealed that hydrogen peroxide (H2O2)-induced apopt...

journal_title：Molecular and cellular biochemistry

authors： Gu Y,Zou Y,Aikawa R,Hayashi D,Kudoh S,Yamauchi T,Uozumi H,Zhu W,Kadowaki T,Yazaki Y,Komuro I

更新日期：2001-07-01 00:00:00

abstract：:Connection between oxidative stress and clinical outcome in acute ischemic stroke (AIS) has been poorly investigated. This study was aimed to assess redox state (through measurement of oxidative stress markers) of patients with acute ischemic stroke during different stages of follow-up period, and to find association ...

journal_title：Molecular and cellular biochemistry

authors： Paspalj D,Nikic P,Savic M,Djuric D,Simanic I,Zivkovic V,Jeremic N,Srejovic I,Jakovljevic V

更新日期：2015-08-01 00:00:00

abstract：:Triple-negative breast cancer (TNBC), which accounts for 10-20% of all breast cancers, has the worst prognosis. Although chemotherapy treatment is a standard for TNBC, it lacks a specific target. Therefore, new therapeutic strategies are required to be investigated. In this study, a combined doxorubicin (DOX) and smal...

journal_title：Molecular and cellular biochemistry

authors： Ciocan-Cȃrtiţă CA,Jurj A,Raduly L,Cojocneanu R,Moldovan A,Pileczki V,Pop LA,Budişan L,Braicu C,Korban SS,Berindan-Neagoe I

更新日期：2020-12-01 00:00:00

abstract：:A high molecular weight protein has been isolated as a major polypeptide comprising 85% of the total extractable proteins in the fruit pericarp of the plant Impatiens balsamina. The protein has been purified to homogeneity following fractionation of the crude cell supernatant with ammonium sulphate, chromatography on ...

journal_title：Molecular and cellular biochemistry

authors： Pal M,Biswas S

更新日期：1994-01-26 00:00:00

abstract：:Chemotherapy remains the core of anticancer treatment. However, despite the tremendous strides made in the development of targeted anticancer therapies, emergence of resistance to chemotherapeutic drugs is still a major obstacle in the successful management of resistant tumors. Therefore, profound investigation into t...

journal_title：Molecular and cellular biochemistry

authors： Peng L,Zhu H,Wang J,Sui H,Zhang H,Jin C,Li L,Xu T,Miao R

更新日期：2015-07-01 00:00:00

abstract：:Adipose-derived stem cells (ADSCs) have been considered as the optimal cells for regenerative medicine because ADSCs have the potential of multi-directional differentiation. To study the mechanisms of ADSCs differentiation, we analyzed microarray of GSE37329. GSE37329 was downloaded from Gene Expression Omnibus includ...

journal_title：Molecular and cellular biochemistry

authors： Ren Y,Han C,Wang J,Jia Y,Kong L,Eerdun T,Wu L,Jiang D

更新日期：2015-02-01 00:00:00

abstract：:The main purpose of this study was to determine the subchronic effects of low concentrations of tumor necrosis factor alpha (TNF alpha) on the inotropic response and on the cellular level of high energy phosphates of cardiomyocytes. Therefore, the inotropic response of cultured neonatal rat heart cells to 10(-5) M iso...

journal_title：Molecular and cellular biochemistry

authors： Boekstegers P,Kainz I,Giehrl W,Peter W,Werdan K

更新日期：1996-03-23 00:00:00

abstract：:Sarcolemmal Ca2+/Mg2+ ecto-ATPase (Myoglein; MW 180 kD) is a membrane bound enzyme which requires a millimolar concentration of either Ca2+ or Mg2+ for maximal hydrolysis of ATP. The isoelectric point (pI) of the cardiac ecto-ATPase was 5.7. The purified Ca2+/Mg2+ ecto-ATPase from the rat heart sarcolemmal appeared as...

journal_title：Molecular and cellular biochemistry

authors： Kannan S,Elimban V,Dakshinamurti K,Dhalla NS

更新日期：1998-06-01 00:00:00

abstract：:The molecular signaling events leading to protection from oxidative stress-induced apoptosis upon contact inhibition have not been fully investigated. Previous research has indicated a role for mitogen-activated protein kinases (MAPKs) in the regulation of contact inhibition, and these proteins have also been associat...

journal_title：Molecular and cellular biochemistry

authors： Gaballah M,Slisz M,Hutter-Lobo D

更新日期：2012-01-01 00:00:00