Polymorphisms in twelve candidate genes are associated with growth, muscle lipid profile and meat quality traits in eleven European cattle breeds.

abstract：:The present study demonstrates that protein biosynthesis can be studied in single isolated human scalp hair follicles. The matrix and the sheath are the main regions where amino acids are built in. Incorporation is linear for at least five hours. The newly synthesized proteins can be separated into a water-soluble, a ...

journal_title：Molecular biology reports

authors： Vermorken AJ,Weterings PJ,Bloemendal H

更新日期：1979-02-15 00:00:00

abstract：:HMG proteins were extracted with 5% PCA or 0.35 M NaCl from whole tissue, nuclei or chromatin of the liver of young (19 weeks) and old (118 weeks) male rats. They were resolved on acetic acid-urea polyacrylamide gel. The electrophoretic patterns of the major HMG proteins 1, 2, 14 and 17 of both ages are similar. The i...

journal_title：Molecular biology reports

authors： Thakur MK,Prasad S

更新日期：1991-02-01 00:00:00

abstract：:The mouse double minute 2 (MDM2) gene encodes a phosphoprotein that interacts with P53 and negatively regulates its activity. SNP309 polymorphism (T-G) in the promoter of MDM2 gene has been reported to be associated with enhanced MDM2 expression and tumor development. Many published studies have evaluated the associat...

journal_title：Molecular biology reports

authors： Zhao E,Cui D,Yuan L,Lu W

更新日期：2012-04-01 00:00:00

abstract：:Northeast of China is the main soybean production area, drought and low-temperature tolerance are both main factors involved in reducing soybean yield and limiting planting regions, the most effective way to solve this problem is to breed cultivars with drought and low-temperature tolerance. A set of the BC(2)F(3) lin...

journal_title：Molecular biology reports

authors： Zhang WB,Qiu PC,Jiang HW,Liu CY,Xin da W,Li CD,Hu GH,Chen QS

更新日期：2012-05-01 00:00:00

abstract：:The binding characteristics of the interaction between 3-(2-cyanoethyl) cytosine (CECT) and human serum albumin (HSA) were investigated using fluorescence, UV absorption spectroscopic and molecular modeling techniques under simulative physiological conditions. The intrinsic fluorescence intensity of HSA was decreased ...

journal_title：Molecular biology reports

authors： Cui FL,Hui GQ,Huo RN,Qu GR

更新日期：2012-11-01 00:00:00

abstract：:Immense body of evidence indicates that dysfunction of immune system is implicated in the etiology of schizophrenia. The immune theory of schizophrenia is supported by alterations in cytokine profile in the brain and peripheral blood. Given the strong genetic background of schizophrenia, it might be assumed that aberr...

journal_title：Molecular biology reports

authors： Frydecka D,Misiak B,Beszlej JA,Karabon L,Pawlak-Adamska E,Tomkiewicz A,Partyka A,Jonkisz A,Kiejna A

更新日期：2013-10-01 00:00:00

abstract：:In the post-genomic era, providing a detailed description of protein functions poses a formidable challenge. To gain functional insights, we have to construct many kinds of expression vectors. DNA recombination based on polymerase chain reaction (PCR) and digestion followed by ligation is the preferred method for vect...

journal_title：Molecular biology reports

authors： Pan JS,Zhang ZP,Cai JY,Dong J,Ren JL,Wang XZ

更新日期：2010-03-01 00:00:00

abstract：:Osteoporosis is a common health problem in Mexico, so it is essential to investigate the status of different gene polymorphisms that could serve as genetic susceptibility markers in the Mexican population. Genes with a role in bone metabolism are excellent candidates for association studies. In this study were determi...

journal_title：Molecular biology reports

authors： Falcón-Ramírez E,Casas-Avila L,Cerda-Flores RM,Castro-Hernández C,Rubio-Lightbourn J,Velázquez-Cruz R,Diez-G P,Peñaloza-Espinosa R,Valdés-Flores M

更新日期：2013-03-01 00:00:00

abstract：:CENP-A locates at nucleosome as histone H3-like proteins, and is phosphorylated during mitosis. We investigated the dynamic distribution of p-CENP-A to explore the details of its function. We found that p-CENP-A was phosphorylated at late prophase, and the signal of p-CENP-A arranged at equatorial plate along with nuc...

journal_title：Molecular biology reports

authors： Li D,Liu R,Song L,Zhou H,Chen J,Huang X

更新日期：2008-12-01 00:00:00

abstract：:Regulation of the sumoylation system at the level of gene expression has not yet been explored. To begin to define transcriptional regulatory features, the promoter region for the SUMO1 gene was cloned from human genomic DNA and characterized. Initially, a 532 base pair fragment upstream of and including the predicted...

journal_title：Molecular biology reports

authors： Nanos-Webb A,Deyrieux A,Bian XL,Rosas-Acosta G,Wilson VG

更新日期：2010-03-01 00:00:00

abstract：:As-NUPR1, a stress-related protein, plays an important role in post-diapause during embryonic development in the brine shrimp Artemia sinica. In the present study, successful expression of As-NUPR1 from the cDNA sequence isolated from A. sinica was demonstrated using a prokaryotic expression system. The recombinant pr...

journal_title：Molecular biology reports

authors： Zhang R,Yao F,Cheng C,Chen Y,Lv Y,Li Z,Zhao N,Wang T,Xin W,Zou X,Hou L

更新日期：2014-05-01 00:00:00

abstract：:An improvement in the detection by nucleic acid hybridization of size-fractionated RNA immobilized to nylon-based membranes is described. Electrophoretic transfer of RNA to nylon membranes permits a quantitative determination of different RNA transcripts on the same membrane after sequential hybridization using differ...

journal_title：Molecular biology reports

authors： Khandjian EW

更新日期：1986-01-01 00:00:00

abstract：:This novel orange fluorescent protein (OFP) emits brilliant orange fluorescent light. OFP has high fluorescence quantum yield, fast maturation rate, and stability, which imply this protein should be the most favorable biotechnological tools used to investigate the function of target gene by visualizing, monitoring, an...

journal_title：Molecular biology reports

authors： Liu JM,David WC,Ip DT,Li XH,Li GL,Wu XF,Yue WF,Zhang CX,Miao YG

更新日期：2009-02-01 00:00:00

abstract：:This study was aimed to evaluate the regulation mechanism of cortactin (CTTN) on matrix metalloproteinases 9 (MMP-9) and its relations with Exo70 in invasion of hepatoma carcinoma (HCC) cells. The expression levels of CTTN, Exo70 and MMP-9 were detected in normal hepatocytes and various HCC cells by real-time PCR. The...

journal_title：Molecular biology reports

authors： Zhao G,Zhang H,Huang Z,Lv L,Yan F

更新日期：2016-05-01 00:00:00

abstract：:Initially, we isolated the caffeic acid O-methyltransferase (COMT) gene from Miscanthus sinensis (accession number HM062766.1). Next, we produced transgenic tobacco plants with down-regulated COMT gene expression to study its control of total phenol and lignin content and to perform morphological analysis. These trans...

journal_title：Molecular biology reports

authors： Seong ES,Yoo JH,Lee JG,Kim HY,Hwang IS,Heo K,Kim JK,Lim JD,Sacks EJ,Yu CY

更新日期：2013-02-01 00:00:00

abstract：:CREB-regulated transcription coactivator 3 (CRTC3) was a recently identified protein which played an important role in glucose and lipid metabolism. Previous research showed that the polymorphisms of CRTC3 were associated with obesity in Mexican-Americans. Data on that relationship in Chinese was unavailable so far. S...

journal_title：Molecular biology reports

authors： Ou Z,Wang G,Li Q,Ma Z,Dai M,Zou F

更新日期：2014-01-01 00:00:00

abstract：:The difference in sensitivity of polyphenylalanine synthesis in extracts from Artemia salina and rabbit reticulocytes to inhibition by the Phytolacca americana protein (PAP) has been found to be linked to the source of the supernatant enzyme fraction and not the ribosomes. In the presence of reticulocyte supernatant e...

journal_title：Molecular biology reports

authors： Suits JP,Irvin JD

更新日期：1976-04-01 00:00:00

abstract：:Rice production in recent years is highly affected by rapidly increasing temperatures in the tropical and sub-tropical countries, which threatens the sustainable production in near future. Hence, understanding the heat tolerance mechanism and evolving tolerant varieties is an immense need in the staple crop rice. An e...

journal_title：Molecular biology reports

authors： Wahab MMS,Akkareddy S,Shanthi P,Latha P

更新日期：2020-03-01 00:00:00

abstract：:We reported earlier about the detection of a chromosomally located arsenic operon (arsRBC) in a gram-negative bacterium Pseudomonas fluorescens strain MSP3, which showed resistance to elevated levels of sodium arsenate and sodium arsenite. The genes for arsenic resistance were cloned into the HindIII site of pBluescri...

journal_title：Molecular biology reports

authors： Prithivirajsingh S,Mishra SK,Mahadevan A

更新日期：2001-01-01 00:00:00

abstract：:Induction and break of bud dormancy are important features for perennial plants surviving extreme seasonal variations in climate. However, the molecular mechanism of the dormancy regulation, still remain poorly understood. To better understand the molecular basis of poplar bud dormancy, we used a label-free quantitati...

journal_title：Molecular biology reports

authors： Ning DL,Liu CC,Liu JW,Shen Z,Chen S,Liu F,Wang BC,Yang CP

更新日期：2013-07-01 00:00:00

abstract：:Iron may be implicated in the generation of oxidative stress by the catalyzing the Haber-Weiss or Fenton reaction. On the other hand, oxidative stress has been implicated in the pathogenesis of age-related macular degeneration (AMD) and heme oxygenase-1 (HO-1), encoded by the HMOX1 gene and heme oxygenase-2 (HO-2), en...

journal_title：Molecular biology reports

authors： Synowiec E,Szaflik J,Chmielewska M,Wozniak K,Sklodowska A,Waszczyk M,Dorecka M,Blasiak J,Szaflik JP

更新日期：2012-03-01 00:00:00

abstract：:The complete mitochondrial genome of Zhikong scallop Chlamys farreri is 21,695 bp in length and contains 12 protein-coding genes (the atp8 gene is absent, as in most bivalves), 2 ribosomal RNA genes, and 22 transfer RNA genes. The heavy strand has an overall A+T content of 58.7%. GC and AT skews for the mt genome of C...

journal_title：Molecular biology reports

authors： Xu K,Kanno M,Yu H,Li Q,Kijima A

更新日期：2011-06-01 00:00:00

abstract：:Recombinant plasmids carrying a highly curved DNA structure are sometimes unstable in Escherichia coli. In order to know the underlying mechanism, several plasmids carrying one or two highly bent DNA segment(s) from the human adenovirus type 2 (Ad2) enhancer and/or origin region of phage lambda replication were system...

journal_title：Molecular biology reports

authors： Ohyama T,Miyano M,Sakuma S

更新日期：1999-12-01 00:00:00

abstract：:Late blight caused by Phytophthora infestans is the most important disease of potato. Many efforts have been made to understand molecular mechanism of the durable resistance to address the challenge raised by rapid evolution of the pathogen. A pathogenesis related protein (PR) gene StPRp27 was previously isolated from...

journal_title：Molecular biology reports

authors： Shi X,Tian Z,Liu J,van der Vossen EA,Xie C

更新日期：2012-02-01 00:00:00

abstract：:Recently genetics and epigenetics alterations have been found to be characteristic of malignancy and hence can be used as targets for detection of neoplasia. RAS association domain family protein 1A (RASSF1A) gene hypermethylation has been a subject of interest in recent researches on cancer breast patients. The aim o...

journal_title：Molecular biology reports

authors： Hagrass HA,Pasha HF,Shaheen MA,Abdel Bary EH,Kassem R

更新日期：2014-01-01 00:00:00

abstract：:Spermiogenesis is a developmental process undergoing continuous differentiation to drive a diploid spermatogonium towards a haploid sperm cell. This striking transformation from spermatogonium to spermatozoa is made possible by the stage-specific adaption of cytoskeleton and associated molecular motor proteins. KIFC1 ...

journal_title：Molecular biology reports

authors： Wang YT,Mao H,Hou CC,Sun X,Wang DH,Zhou H,Yang WX

更新日期：2012-07-01 00:00:00

abstract：:Kidney transplantation to treat end-stage renal disease has evolved rapidly from the first successful transplantations to the current widespread use of grafts from both cadaveric and living donors. But acute rejection is still a strong risk factor for chronic rejection in recipients of renal grafts. To investigate pos...

journal_title：Molecular biology reports

authors： Chen G,Mi J,Xiao MZ,Fu YR

更新日期：2012-05-01 00:00:00

abstract：:Eukaryotic 20S proteasomes are complex oligomeric proteins. The maturation process of the 14 different alpha- and beta-subunits has to occur in a highly coordinate manner. In addition beta-subunits are synthesized as proproteins and correct processing has to be guaranteed during complex maturation. The structure forma...

journal_title：Molecular biology reports

authors： Schmidt M,Schmidtke G,Kloetzel PM

更新日期：1997-03-01 00:00:00

abstract：:Selenium compounds have been widely investigated as novel anticancer agents due to high efficacy and selectivity against cancer cells in recent years. This study aimed to research the potential inhibitory effects of seleno-β-lactoglobulin (Se-β-Lg) on HepG2 cells in vitro. MTT results demonstrated that the synthetized...

journal_title：Molecular biology reports

authors： Ji HY,Yu J,Liu AJ

更新日期：2019-10-01 00:00:00

abstract：:Intrinsic bent DNA sites were identified in the 4289 bp segment encompassing the replication zone which directs DNA amplification and transcription of the C3-22 gene of Rhynchosciara americana. Restriction fragments showed reduced electrophoretic mobility in polyacrylamide gels. The 2D modeling of the 3D DNA path and ...

journal_title：Molecular biology reports

authors： Fiorini A,de Gouveia FS,de Soares MA,Stocker AJ,Ciferri RR,Fernandez MA

更新日期：2006-03-01 00:00:00