Dark homogeneous streak dermoscopic pattern correlating with specific KIT mutations in melanoma.

abstract：Importance:The association between psoriasis and risk of cancer remains debatable. Objective:To evaluate the association and risk of cancer in patients with psoriasis or psoriatic arthritis, including risk of specific cancer subtypes. Data Sources:Two databases (PubMed and Embase) were screened from inception to Janu...

journal_title：JAMA dermatology

authors： Vaengebjerg S,Skov L,Egeberg A,Loft ND

更新日期：2020-04-01 00:00:00

abstract：Importance:Dermatofibrosarcoma protuberans (DFSP) is a rare skin cancer that develops in the deep dermis to subcutaneous adipose tissues. A COL1A1-PDGFB gene fusion, leading to the constitutive expression of PDGFB, is the tumorigenic mechanism in most DFSP cases. Objectives:To evaluate the specificity of PDGFB express...

journal_title：JAMA dermatology

authors： Nakamura I,Kariya Y,Okada E,Yasuda M,Matori S,Ishikawa O,Uezato H,Takahashi K

更新日期：2015-12-01 00:00:00

abstract：IMPORTANCE:Basal cell carcinomas (BCCs) are diagnosed by clinical evaluation, which can include dermoscopic evaluation, biopsy, and histopathologic examination. Recent translation of multiphoton microscopy (MPM) to clinical practice raises the possibility of noninvasive, label-free in vivo imaging of BCCs that could re...

journal_title：JAMA dermatology

authors： Balu M,Zachary CB,Harris RM,Krasieva TB,König K,Tromberg BJ,Kelly KM

更新日期：2015-10-01 00:00:00

abstract：IMPORTANCE:Purse-string suture is a closure method that purportedly reduces the scar area compared with second intention healing. Randomized clinical trials comparing these 2 methods appear to be limited or absent. OBJECTIVE:To determine if purse-string suture improves cosmetic outcome, healing time, and scar to defec...

journal_title：JAMA dermatology

authors： Joo J,Custis T,Armstrong AW,King TH,Omlin K,Kappel ST,Eisen DB

更新日期：2015-03-01 00:00:00

abstract：IMPORTANCE:Cryolipolysis is the noninvasive reduction of fat with localized cutaneous cooling. Since initial introduction, over 650,000 cryolipolysis treatment cycles have been performed worldwide. We present a previously unreported, rare adverse effect following cryolipolysis: paradoxical adipose hyperplasia. OBSERVA...

journal_title：JAMA dermatology

authors： Jalian HR,Avram MM,Garibyan L,Mihm MC,Anderson RR

更新日期：2014-03-01 00:00:00

abstract：Importance:Increased rates of autoimmune conditions have been reported in association with systemic lupus erythematosus (SLE). Little is known about coexisting autoimmune conditions in patients with cutaneous lupus erythematosus (CLE) without SLE. Objective:To determine the prevalence and risk factors of having coexis...

journal_title：JAMA dermatology

authors： Kunzler E,Hynan LS,Chong BF

更新日期：2018-06-01 00:00:00

abstract：Importance:Erythromelalgia is a clinical diagnosis based on intermittent warmth, erythema, and pain in the distal extremities. One problem facing physicians is how to objectively test for this disease. Given that other painful conditions of the distal extremities (ie, neuropathy related to human immunodeficiency virus,...

journal_title：JAMA dermatology

authors： Mantyh WG,Dyck PJB,Dyck PJ,Engelstad JK,Litchy WJ,Sandroni P,Davis MDP

更新日期：2017-02-01 00:00:00

abstract：Importance:Cutaneous squamous cell carcinoma (cSCC) has metastatic potential, but the prognostic value of current staging systems in nonselected patients is uncertain. Objective:To assess the effect of risk factors for metastasis and to evaluate validity and usefulness of 4 staging systems for cSCC using population-ba...

journal_title：JAMA dermatology

authors： Roscher I,Falk RS,Vos L,Clausen OPF,Helsing P,Gjersvik P,Robsahm TE

更新日期：2018-04-01 00:00:00

abstract：IMPORTANCE:Worse survival among patients with melanoma has been demonstrated in middle-aged and older men compared with women, but few studies have explored survival differences by sex in adolescents and young adults, in whom melanoma is the third most common cancer. Focusing on sex disparities in survival among younge...

journal_title：JAMA dermatology

authors： Gamba CS,Clarke CA,Keegan TH,Tao L,Swetter SM

更新日期：2013-08-01 00:00:00

abstract：Importance:Psoriasis is associated with an increased risk of cardiovascular diseases. Subclinical atherosclerosis in patients with psoriasis has not been compared with other conditions associated with increased cardiovascular risk and more rigorous cardiovascular disease screening, such as type 2 diabetes. Objective:T...

journal_title：JAMA dermatology

authors： Mansouri B,Kivelevitch D,Natarajan B,Joshi AA,Ryan C,Benjegerdes K,Schussler JM,Rader DJ,Reilly MP,Menter A,Mehta NN

更新日期：2016-11-01 00:00:00

abstract：Importance:Granuloma faciale (GF) is a rare, benign inflammatory dermatosis of unknown cause. Some reports have suggested that it could be part of the spectrum of IgG4-related sclerosing diseases. Granuloma faciale is characterized by single or multiple red-brown nodules, most frequently occurring on the face, and it c...

journal_title：JAMA dermatology

authors： Morgado-Carrasco D,Giavedoni P,Mascaró JM Jr,Iranzo P

更新日期：2018-11-01 00:00:00

abstract：Clinical Question:Which treatments have been shown to be effective in randomized clinical trials (RCTs) for hidradenitis suppurativa (HS) in adults? Bottom Line:There is high-quality evidence of benefit from adalimumab given weekly, while every other week dosing is ineffective, with reductions in Dermatology Life Qual...

journal_title：JAMA dermatology

authors： Ingram JR

更新日期：2017-05-01 00:00:00

abstract：Importance:Erythropoietic protoporphyria (EPP) is a rare hereditary disease of heme biosynthesis that manifests as severe photosensitivity and hepatotoxicity. There have been no effective treatments to date. Cimetidine has been shown to inhibit heme biosynthesis and results in symptomatic improvement in patients with a...

journal_title：JAMA dermatology

authors： Tu JH,Sheu SL,Teng JM

更新日期：2016-11-01 00:00:00

abstract：Importance:The US Food and Drug Administration approves Class III medical devices via the premarket approval pathway, often requiring clinical data on safety and efficacy. Manufacturers can submit incremental device changes via supplemental applications, which are not subjected to such vetting measures and can cause un...

journal_title：JAMA dermatology

authors： Ezaldein HH,Scott JF,Yin ES,Ventura A,DeRuyter NP,Leffell DJ

更新日期：2018-03-01 00:00:00

abstract：Importance:Concerns have been raised about the use of radiotherapy (RT) by dermatologists. Little is known about temporal trends in payment for RT among dermatologists. Objective:To characterize changes in RT use and payment among dermatologists treating patients enrolled in Medicare. Design, Setting, and Participant...

journal_title：JAMA dermatology

authors： Nguyen KD,Chen HW,Adamson AS

更新日期：2020-12-23 00:00:00

abstract：OBJECTIVE:To compare the prevalence and incidence of type 2 diabetes mellitus between patients with psoriasis and those without psoriasis. DATA SOURCES:MEDLINE, EMBASE, and Cochrane Database of Systematic Reviews between January 1, 1980, and January 1, 2012. STUDY SELECTION:Observational (cohort, case-control, and cr...

journal_title：JAMA dermatology

authors： Armstrong AW,Harskamp CT,Armstrong EJ

更新日期：2013-01-01 00:00:00

abstract：Importance:Drug-induced hypersensitivity syndrome (DIHS), also known as drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome, is a potentially life-threatening reaction to medications with a mortality rate up to 10%. Standard therapy involves the use of systemic corticosteroids with tapering doses ext...

journal_title：JAMA dermatology

authors： Kirchhof MG,Wong A,Dutz JP

更新日期：2016-11-01 00:00:00

abstract：IMPORTANCE:Omalizumab has emerged as a novel and effective treatment option for patients with antihistamine-resistant chronic urticaria. It is unclear whether patients with recurrent urticaria symptoms after discontinuation of omalizumab treatment can benefit from retreatment. OBJECTIVE:To assess the response of patie...

journal_title：JAMA dermatology

authors： Metz M,Ohanyan T,Church MK,Maurer M

更新日期：2014-03-01 00:00:00

abstract：Importance:Advanced practice professionals (APPs) such as nurse practitioners and physician assistants independently perform a large number and variety of dermatologic procedures, but little is known about how the number and scope of these procedures have changed over time. Objective:To examine the trends in scope and...

journal_title：JAMA dermatology

authors： Zhang M,Zippin J,Kaffenberger B

更新日期：2018-09-01 00:00:00

abstract：Importance:Exercise is recommended as an adjuvant treatment for venous leg ulceration (VLU) to improve calf muscle pump function. However, the association of exercise with VLU healing has not been properly aggregated, and the effectiveness of different exercise interventions has not been characterized. Objective:To su...

journal_title：JAMA dermatology

authors： Jull A,Slark J,Parsons J

更新日期：2018-11-01 00:00:00

abstract：Importance:There is limited information regarding the influence of patient demographics, tumor characteristics, and treatment type on the survival of patients with dermatofibrosarcoma protuberans (DFSP). Objective:To assess prognostic factors and to evaluate the influence of treatment modality on overall survival of p...

journal_title：JAMA dermatology

authors： Criscito MC,Martires KJ,Stein JA

更新日期：2016-12-01 00:00:00

abstract：IMPORTANCE:Pseudoaneurysm is a well-known complication of trauma and iatrogenic injury to the vasculature. We report 3 cases of postsurgical pseudoaneurysm after Mohs surgery. OBSERVATIONS:Three patients who underwent Mohs surgery for nonmelanoma skin cancers presented between 2 and 4 weeks after surgery with several ...

journal_title：JAMA dermatology

authors： Dunbar SW,Hurst EA

更新日期：2014-05-01 00:00:00

abstract：IMPORTANCE:Acquired cutis laxa is a rare cutaneous manifestation of hematologic malignancy. We report a case of γ heavy chain deposition disease (HCDD) associated with acquired cutis laxa, renal involvement, and hypocomplementemia and propose a mechanism of elastic fiber degradation in the skin of this patient with HCD...

journal_title：JAMA dermatology

authors： O'Malley JT,D'Agati VD,Sherman WH,Grossman ME

更新日期：2014-11-01 00:00:00

abstract：Importance:Because moisturizer use is critical for the prevention and treatment of numerous dermatological conditions, patients frequently request product recommendations from dermatologists. Objective:To determine the product performance characteristics and ingredients of best-selling moisturizers. Design and Settin...

journal_title：JAMA dermatology

authors： Xu S,Kwa M,Lohman ME,Evers-Meltzer R,Silverberg JI

更新日期：2017-11-01 00:00:00

abstract：IMPORTANCE:Evidence-based treatment guidelines are not available for primary cutaneous mucinous carcinoma (PCMC). OBJECTIVE:To assess outcomes associated with surgical treatment of PCMC. DATA SOURCES:MEDLINE, Cumulative Index to Nursing and Allied Health, and Embase from 1952 to 2010. Search terms were "primary cutan...

journal_title：JAMA dermatology

authors： Kamalpour L,Brindise RT,Nodzenski M,Bach DQ,Veledar E,Alam M

更新日期：2014-04-01 00:00:00

abstract：Importance:Incidence rates of skin cancer are increasing globally, and the correct classification of skin lesions (SLs) into benign and malignant tissue remains a continuous challenge. A collective intelligence approach to skin cancer detection may improve accuracy. Objective:To evaluate the performance of 2 well-know...

journal_title：JAMA dermatology

authors： Kurvers RH,Krause J,Argenziano G,Zalaudek I,Wolf M

更新日期：2015-12-01 00:00:00

abstract：Importance:Population-level disease metrics are critical to guide the distribution of resources and implementation of public health initiatives. Internet search data reflect population interest in health topics and may be an alternative metric of disease characteristics when traditional sources are lacking, such as in ...

journal_title：JAMA dermatology

authors： Wehner MR,Nead KT,Linos E

更新日期：2017-09-01 00:00:00

abstract：Importance:The dupilumab regimen of 300 mg every 2 weeks is approved for uncontrolled, moderate to severe atopic dermatitis (AD). Objective:To assess the efficacy and safety of different dupilumab regimens in maintaining response after 16 weeks of initial treatment. Design, Setting, and Participants:The Study to Conf...

journal_title：JAMA dermatology

authors： Worm M,Simpson EL,Thaçi D,Bissonnette R,Lacour JP,Beissert S,Kawashima M,Ferrándiz C,Smith CH,Beck LA,Chan KC,Chen Z,Akinlade B,Hultsch T,Staudinger H,Gadkari A,Eckert L,Davis JD,Rajadhyaksha M,Graham NMH,Pirozzi

更新日期：2020-02-01 00:00:00

abstract：IMPORTANCE:Topical corticosteroids are the current first-line therapy for vulvar lichen sclerosus (VLS). UV-A1 phototherapy may be a promising alternative treatment option, but controlled studies are lacking. OBJECTIVE:To compare the efficacy of high-potent topical corticosteroids with UV-A1 phototherapy in the treatm...

journal_title：JAMA dermatology

authors： Terras S,Gambichler T,Moritz RK,Stücker M,Kreuter A

更新日期：2014-06-01 00:00:00

abstract：IMPORTANCE:How complications associated with chronic venous insufficiency (CVI) develop is not clear. The central source of the complications is likely a dysfunction of the calf muscle pump, which includes veins and their valves, the gastrocnemius and other lower leg and foot muscles as well as the nerves supplying the...

journal_title：JAMA dermatology

authors： Yim E,Vivas A,Maderal A,Kirsner RS

更新日期：2014-04-01 00:00:00