Acquired cutis laxa associated with heavy chain deposition disease involving dermal elastic fibers.

abstract：IMPORTANCE:Sarcoidosis is a chronic granulomatous disease for which there are limited therapeutic options. This is the first randomized, placebo-controlled study to demonstrate that antimycobacterial therapy reduces lesion diameter and disease severity among patients with chronic cutaneous sarcoidosis. OBJECTIVE:To ev...

journal_title：JAMA dermatology

authors： Drake WP,Oswald-Richter K,Richmond BW,Isom J,Burke VE,Algood H,Braun N,Taylor T,Pandit KV,Aboud C,Yu C,Kaminski N,Boyd AS,King LE

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:To compare the prevalence and incidence of type 2 diabetes mellitus between patients with psoriasis and those without psoriasis. DATA SOURCES:MEDLINE, EMBASE, and Cochrane Database of Systematic Reviews between January 1, 1980, and January 1, 2012. STUDY SELECTION:Observational (cohort, case-control, and cr...

journal_title：JAMA dermatology

authors： Armstrong AW,Harskamp CT,Armstrong EJ

更新日期：2013-01-01 00:00:00

abstract：IMPORTANCE:Ustekinumab is a human monoclonal antibody that binds to the shared p40 subunit of interleukin (IL) 12 and IL-23. It is approved in the United States for adults (>18 years) with moderate to severe plaque psoriasis who are candidates for phototherapy or systemic therapy. In 1 phase 2 trial of ustekinumab for ...

journal_title：JAMA dermatology

authors： Stamell EF,Kutner A,Viola K,Cohen SR

更新日期：2013-12-01 00:00:00

abstract：Importance:There is ongoing controversy about the adverse events of finasteride, a drug used in the management of alopecia and benign prostatic hyperplasia (BPH). In 2012, reports started emerging on men who had used finasteride and either attempted or completed suicide. Objective:To investigate the association of sui...

journal_title：JAMA dermatology

authors： Nguyen DD,Marchese M,Cone EB,Paciotti M,Basaria S,Bhojani N,Trinh QD

更新日期：2021-01-01 00:00:00

abstract：IMPORTANCE:Although cutaneous warts are common lesions, full remission is not always achieved with conventional therapies. Laser modalities including carbon dioxide (CO2), erbium:yttrium-aluminum-garnet (Er:YAG), pulsed dye (PDL), and Nd:YAG have been investigated as alternative treatments for warts. OBJECTIVE:To revi...

journal_title：JAMA dermatology

authors： Nguyen J,Korta DZ,Chapman LW,Kelly KM

更新日期：2016-09-01 00:00:00

abstract：Importance:Psoriasis is associated with an increased risk of cardiovascular diseases. Subclinical atherosclerosis in patients with psoriasis has not been compared with other conditions associated with increased cardiovascular risk and more rigorous cardiovascular disease screening, such as type 2 diabetes. Objective:T...

journal_title：JAMA dermatology

authors： Mansouri B,Kivelevitch D,Natarajan B,Joshi AA,Ryan C,Benjegerdes K,Schussler JM,Rader DJ,Reilly MP,Menter A,Mehta NN

更新日期：2016-11-01 00:00:00

abstract：Importance:Atopic dermatitis (AD) and allergic contact dermatitis (ACD) have a dynamic relationship not yet fully understood. Investigation has been limited thus far by a paucity of data on the overlap of these disorders in pediatric patients. Objective:To use data from the Pediatric Contact Dermatitis Registry to elu...

journal_title：JAMA dermatology

authors： Jacob SE,McGowan M,Silverberg NB,Pelletier JL,Fonacier L,Mousdicas N,Powell D,Scheman A,Goldenberg A

更新日期：2017-08-01 00:00:00

abstract：Importance:Previous studies suggest that depression and anxiety are common in patients with hidradenitis suppurativa (HS), more so than other dermatological conditions. Yet, to the authors' knowledge, no previous systematic review or meta-analysis has estimated the prevalence or odds ratio (OR) for those psychiatric co...

journal_title：JAMA dermatology

authors： Machado MO,Stergiopoulos V,Maes M,Kurdyak PA,Lin PY,Wang LJ,Shyu YC,Firth J,Koyanagi A,Solmi M,Alavi A,Piguet V,Carvalho AF

更新日期：2019-06-05 00:00:00

abstract：Importance:Cutaneous squamous cell carcinoma (cSCC) has metastatic potential, but the prognostic value of current staging systems in nonselected patients is uncertain. Objective:To assess the effect of risk factors for metastasis and to evaluate validity and usefulness of 4 staging systems for cSCC using population-ba...

journal_title：JAMA dermatology

authors： Roscher I,Falk RS,Vos L,Clausen OPF,Helsing P,Gjersvik P,Robsahm TE

更新日期：2018-04-01 00:00:00

abstract：IMPORTANCE:Describing the relationship between the availability of free prescription drug samples and dermatologists' prescribing patterns on a national scale can help inform policy guidelines on the use of free samples in a physician's office. OBJECTIVES:To investigate the relationships between free drug samples and ...

journal_title：JAMA dermatology

authors： Hurley MP,Stafford RS,Lane AT

更新日期：2014-05-01 00:00:00

abstract：IMPORTANCE:Cryolipolysis is the noninvasive reduction of fat with localized cutaneous cooling. Since initial introduction, over 650,000 cryolipolysis treatment cycles have been performed worldwide. We present a previously unreported, rare adverse effect following cryolipolysis: paradoxical adipose hyperplasia. OBSERVA...

journal_title：JAMA dermatology

authors： Jalian HR,Avram MM,Garibyan L,Mihm MC,Anderson RR

更新日期：2014-03-01 00:00:00

abstract：IMPORTANCE:Recently, a group of melanocytic tumors with loss of BAP1 expression has been described. The lesions may occur sporadically or as part of a familial cancer syndrome. They have distinct histopathologic features characterized by a nevus like silhouette and cytologic composition of large epithelioid melanocytes...

journal_title：JAMA dermatology

authors： Busam KJ,Wanna M,Wiesner T

更新日期：2013-03-01 00:00:00

abstract：Importance:Because moisturizer use is critical for the prevention and treatment of numerous dermatological conditions, patients frequently request product recommendations from dermatologists. Objective:To determine the product performance characteristics and ingredients of best-selling moisturizers. Design and Settin...

journal_title：JAMA dermatology

authors： Xu S,Kwa M,Lohman ME,Evers-Meltzer R,Silverberg JI

更新日期：2017-11-01 00:00:00

abstract：Importance:There are limited data among young adults on sunscreen use during childhood and adulthood and on the association of sunscreen use with melanoma risk. Objective:To assess correlates of early-life sunscreen use and the association between sunscreen use and risk of cutaneous melanoma before age 40 years. Desi...

journal_title：JAMA dermatology

authors： Watts CG,Drummond M,Goumas C,Schmid H,Armstrong BK,Aitken JF,Jenkins MA,Giles GG,Hopper JL,Mann GJ,Cust AE

更新日期：2018-09-01 00:00:00

abstract：IMPORTANCE:Mitotic rate is now recognized as having independent prognostic significance in melanoma survival. However, its clinicopathologic associations have not been the focus of any previous study. OBJECTIVE:To identify a set of patient and tumor characteristics associated with high-mitotic-rate melanoma with the a...

journal_title：JAMA dermatology

authors： Shen S,Wolfe R,McLean CA,Haskett M,Kelly JW

更新日期：2014-10-01 00:00:00

abstract：IMPORTANCE:Psoriasis and atopic dermatitis (AD) are inflammatory diseases thought to be mediated by helper T-cell subtypes 1 and 2 (TH1 and TH2), respectively. Although psoriasis and AD show histopathologic differences during chronic disease, they are difficult to distinguish histologically during erythrodermic exacerb...

journal_title：JAMA dermatology

authors： Moy AP,Murali M,Kroshinsky D,Duncan LM,Nazarian RM

更新日期：2015-07-01 00:00:00

abstract：IMPORTANCE:Purse-string suture is a closure method that purportedly reduces the scar area compared with second intention healing. Randomized clinical trials comparing these 2 methods appear to be limited or absent. OBJECTIVE:To determine if purse-string suture improves cosmetic outcome, healing time, and scar to defec...

journal_title：JAMA dermatology

authors： Joo J,Custis T,Armstrong AW,King TH,Omlin K,Kappel ST,Eisen DB

更新日期：2015-03-01 00:00:00

abstract：IMPORTANCE:Nevi are among the strongest risk factors for melanoma. However, little is known about the association of many total nevi (TN) or atypical nevi (AN) with tumor thickness. OBJECTIVES:To examine the association between age and the number of TN and AN and to explore whether there was a relationship between TN ...

journal_title：JAMA dermatology

authors： Geller AC,Mayer JE,Sober AJ,Miller DR,Argenziano G,Johnson TM,Swetter SM

更新日期：2016-04-01 00:00:00

abstract：Importance:Systemic and inhaled corticosteroids negatively affect bone remodeling and cause osteoporosis and bone fracture when given continuously or in high doses. However, risk of osteoporosis and major osteoporotic fracture (MOF) after application of topical corticosteroids (TCSs) is largely unexplored. Objective:T...

journal_title：JAMA dermatology

authors： Egeberg A,Schwarz P,Harsløf T,Andersen YMF,Pottegård A,Hallas J,Thyssen JP

更新日期：2021-01-20 00:00:00

abstract：Importance:Chronic graft-vs-host-disease (cGVHD) after allogeneic stem cell transplantation (AHSCT) may resemble autoimmune diseases. Anti-MDA5 (melanoma differentiation-associated gene 5) dermatopulmonary syndrome is a subset of dermatomyositis defined by specific clinical features and detection of anti-MDA5-antibodie...

journal_title：JAMA dermatology

authors： Lepelletier C,Bengoufa D,Lyes Z,de Masson A,Chasset F,Jachiet M,Michonneau D,Robin M,Peffault de Latour R,Sicre de Fontbrune F,Tandjaoui-Lambiotte Y,Bensussan A,Rybojad M,Tazi A,Bagot M,Socié G,Bergeron A,Bouaziz JD

更新日期：2017-02-01 00:00:00

abstract：Importance:Skin cancer, the most common cancer in the United States, is highly associated with outdoor and indoor tanning behaviors. Although indoor tanning has been suggested to be more common among sexual minority (self-reported as homosexual, gay, or bisexual) men compared with heterosexual men, whether rates of ski...

journal_title：JAMA dermatology

authors： Mansh M,Katz KA,Linos E,Chren MM,Arron S

更新日期：2015-12-01 00:00:00

abstract：IMPORTANCE:Hidradenitis suppurativa (HS) is a chronic cutaneous disease with acutely painful flares that require appropriate and timely treatment. OBJECTIVE:To assess how individuals with HS utilize medical care, especially emergency department (ED) care, a high-cost setting, and to describe the health care costs for ...

journal_title：JAMA dermatology

authors： Kirby JS,Miller JJ,Adams DR,Leslie D

更新日期：2014-09-01 00:00:00

abstract：Importance:The association between psoriasis and risk of cancer remains debatable. Objective:To evaluate the association and risk of cancer in patients with psoriasis or psoriatic arthritis, including risk of specific cancer subtypes. Data Sources:Two databases (PubMed and Embase) were screened from inception to Janu...

journal_title：JAMA dermatology

authors： Vaengebjerg S,Skov L,Egeberg A,Loft ND

更新日期：2020-04-01 00:00:00

abstract：Importance:Drug-induced hypersensitivity syndrome (DIHS), also known as drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome, is a potentially life-threatening reaction to medications with a mortality rate up to 10%. Standard therapy involves the use of systemic corticosteroids with tapering doses ext...

journal_title：JAMA dermatology

authors： Kirchhof MG,Wong A,Dutz JP

更新日期：2016-11-01 00:00:00

abstract：Importance:The differential diagnosis between proliferative nodules (PNs) and melanoma arising in congenital melanocytic nevi (CMN) is crucial, as patients with PNs most often experience no increased risk of melanoma with metastases and death. Objective:To analyze the utility of immunohistochemistry and fluorescence i...

journal_title：JAMA dermatology

authors： Vergier B,Laharanne E,Prochazkova-Carlotti M,de la Fouchardière A,Merlio JP,Kadlub N,Avril MF,Bodemer C,Lacoste C,Boralevi F,Taieb A,Ezzedine K,Fraitag S

更新日期：2016-10-01 00:00:00

abstract：IMPORTANCE:Basal cell carcinomas (BCCs) are diagnosed by clinical evaluation, which can include dermoscopic evaluation, biopsy, and histopathologic examination. Recent translation of multiphoton microscopy (MPM) to clinical practice raises the possibility of noninvasive, label-free in vivo imaging of BCCs that could re...

journal_title：JAMA dermatology

authors： Balu M,Zachary CB,Harris RM,Krasieva TB,König K,Tromberg BJ,Kelly KM

更新日期：2015-10-01 00:00:00

abstract：Importance:Population-level disease metrics are critical to guide the distribution of resources and implementation of public health initiatives. Internet search data reflect population interest in health topics and may be an alternative metric of disease characteristics when traditional sources are lacking, such as in ...

journal_title：JAMA dermatology

authors： Wehner MR,Nead KT,Linos E

更新日期：2017-09-01 00:00:00

abstract：Importance:The US Food and Drug Administration approves Class III medical devices via the premarket approval pathway, often requiring clinical data on safety and efficacy. Manufacturers can submit incremental device changes via supplemental applications, which are not subjected to such vetting measures and can cause un...

journal_title：JAMA dermatology

authors： Ezaldein HH,Scott JF,Yin ES,Ventura A,DeRuyter NP,Leffell DJ

更新日期：2018-03-01 00:00:00

abstract：Importance:Staged excision of lentigo maligna (LM) often requires multiple stages and can result in significant cosmetic morbidity. Imiquimod cream has been used off-label as monotherapy in the treatment of LM and may be used in the neoadjuvant setting prior to staged excision as a strategy to reduce the size of the su...

journal_title：JAMA dermatology

authors： Donigan JM,Hyde MA,Goldgar DE,Hadley ML,Bowling M,Bowen GM

更新日期：2018-08-01 00:00:00

abstract：Importance:Granuloma faciale (GF) is a rare, benign inflammatory dermatosis of unknown cause. Some reports have suggested that it could be part of the spectrum of IgG4-related sclerosing diseases. Granuloma faciale is characterized by single or multiple red-brown nodules, most frequently occurring on the face, and it c...

journal_title：JAMA dermatology

authors： Morgado-Carrasco D,Giavedoni P,Mascaró JM Jr,Iranzo P

更新日期：2018-11-01 00:00:00