Interventions for Hidradenitis Suppurativa: Updated Summary of an Original Cochrane Review.

Abstract:

Clinical Question:Which treatments have been shown to be effective in randomized clinical trials (RCTs) for hidradenitis suppurativa (HS) in adults? Bottom Line:There is high-quality evidence of benefit from adalimumab given weekly, while every other week dosing is ineffective, with reductions in Dermatology Life Quality Index (DLQI) scores compared with placebo of 2.8 points (95% CI, -3.7 to -2.0 points) and 1.6 points (95% CI, -3.9 to 0.6 points), respectively. Moderate-quality evidence suggests that infliximab is beneficial; RCT evidence for other interventions was lower in quality or absent, limiting further conclusions.

journal_name

JAMA Dermatol

journal_title

JAMA dermatology

authors

Ingram JR

doi

10.1001/jamadermatol.2017.0432

subject

Has Abstract

pub_date

2017-05-01 00:00:00

pages

458-459

issue

5

eissn

2168-6068

issn

2168-6084

pii

2612719

journal_volume

153

pub_type

杂志文章
  • Comparison of Posttransplant Dermatologic Diseases by Race.

    abstract:Importance:The risk for skin cancer has been well characterized in white organ transplant recipients (OTRs); however, most patients on the waiting list for organ transplant in the United States are nonwhite. Little is known about cutaneous disease and skin cancer risk in this OTR population. Objective:To compare the i...

    journal_title:JAMA dermatology

    pub_type: 杂志文章

    doi:10.1001/jamadermatol.2017.0045

    authors: Chung CL,Nadhan KS,Shaver CM,Ogrich LM,Abdelmalek M,Cusack CA,Malat GE,Pritchett EN,Doyle A

    更新日期:2017-06-01 00:00:00

  • Efficacy and Safety of Multiple Dupilumab Dose Regimens After Initial Successful Treatment in Patients With Atopic Dermatitis: A Randomized Clinical Trial.

    abstract:Importance:The dupilumab regimen of 300 mg every 2 weeks is approved for uncontrolled, moderate to severe atopic dermatitis (AD). Objective:To assess the efficacy and safety of different dupilumab regimens in maintaining response after 16 weeks of initial treatment. Design, Setting, and Participants:The Study to Conf...

    journal_title:JAMA dermatology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1001/jamadermatol.2019.3617

    authors: Worm M,Simpson EL,Thaçi D,Bissonnette R,Lacour JP,Beissert S,Kawashima M,Ferrándiz C,Smith CH,Beck LA,Chan KC,Chen Z,Akinlade B,Hultsch T,Staudinger H,Gadkari A,Eckert L,Davis JD,Rajadhyaksha M,Graham NMH,Pirozzi

    更新日期:2020-02-01 00:00:00

  • Transparency and Dermatologic Device Approval by the US Food and Drug Administration.

    abstract:Importance:The US Food and Drug Administration approves Class III medical devices via the premarket approval pathway, often requiring clinical data on safety and efficacy. Manufacturers can submit incremental device changes via supplemental applications, which are not subjected to such vetting measures and can cause un...

    journal_title:JAMA dermatology

    pub_type: 杂志文章

    doi:10.1001/jamadermatol.2017.5757

    authors: Ezaldein HH,Scott JF,Yin ES,Ventura A,DeRuyter NP,Leffell DJ

    更新日期:2018-03-01 00:00:00

  • Detection Accuracy of Collective Intelligence Assessments for Skin Cancer Diagnosis.

    abstract:Importance:Incidence rates of skin cancer are increasing globally, and the correct classification of skin lesions (SLs) into benign and malignant tissue remains a continuous challenge. A collective intelligence approach to skin cancer detection may improve accuracy. Objective:To evaluate the performance of 2 well-know...

    journal_title:JAMA dermatology

    pub_type: 杂志文章

    doi:10.1001/jamadermatol.2015.3149

    authors: Kurvers RH,Krause J,Argenziano G,Zalaudek I,Wolf M

    更新日期:2015-12-01 00:00:00

  • Changes in Use of Radiotherapy Among Dermatologists From 2013 to 2017.

    abstract:Importance:Concerns have been raised about the use of radiotherapy (RT) by dermatologists. Little is known about temporal trends in payment for RT among dermatologists. Objective:To characterize changes in RT use and payment among dermatologists treating patients enrolled in Medicare. Design, Setting, and Participant...

    journal_title:JAMA dermatology

    pub_type: 杂志文章

    doi:10.1001/jamadermatol.2020.4931

    authors: Nguyen KD,Chen HW,Adamson AS

    更新日期:2020-12-23 00:00:00

  • Costs and Consequences Associated With Misdiagnosed Lower Extremity Cellulitis.

    abstract:Importance:Inflammatory dermatoses of the lower extremity are often misdiagnosed as cellulitis (aka "pseudocellulitis") and treated with antibiotics and/or hospitalization. There is limited data on the cost and complications from misdiagnosed cellulitis. Objective:To characterize the national health care burden of mis...

    journal_title:JAMA dermatology

    pub_type: 杂志文章

    doi:10.1001/jamadermatol.2016.3816

    authors: Weng QY,Raff AB,Cohen JM,Gunasekera N,Okhovat JP,Vedak P,Joyce C,Kroshinsky D,Mostaghimi A

    更新日期:2017-02-01 00:00:00

  • Association of Histologic Regression With a Favorable Outcome in Patients With Stage 1 and Stage 2 Cutaneous Melanoma.

    abstract:Importance:Although regression is commonly observed in cutaneous melanoma, it is uncertain whether it is associated with patient prognosis. Objective:To determine whether histologically confirmed regression was associated with better or worse survival in patients with primary cutaneous melanoma. Design, Setting, and ...

    journal_title:JAMA dermatology

    pub_type: 杂志文章

    doi:10.1001/jamadermatol.2020.5032

    authors: El Sharouni MA,Aivazian K,Witkamp AJ,Sigurdsson V,van Gils CH,Scolyer RA,Thompson JF,van Diest PJ,Lo SN

    更新日期:2020-12-23 00:00:00

  • Improvement of survival in patients with primary cutaneous diffuse large B-cell lymphoma, leg type, in France.

    abstract:IMPORTANCE:Primary cutaneous diffuse large B-cell lymphoma, leg type (PCDLBCL-LT), occurs in elderly patients and has been considered as a lymphoma with a poor prognosis, with estimated 5-year specific survival rates of approximately 50%. The hypothesis of an improvement in prognosis over time has not been studied. OB...

    journal_title:JAMA dermatology

    pub_type: 杂志文章,多中心研究

    doi:10.1001/jamadermatol.2013.7452

    authors: Grange F,Joly P,Barbe C,Bagot M,Dalle S,Ingen-Housz-Oro S,Maubec E,D'Incan M,Ram-Wolff C,Dalac S,Templier I,Esteve E,Quereux G,Machet L,Leduc M,Dereure O,Laroche L,Saiag P,Vergier B,Beylot-Barry M

    更新日期:2014-05-01 00:00:00

  • Combining biologic therapies with other systemic treatments in psoriasis: evidence-based, best-practice recommendations from the Medical Board of the National Psoriasis Foundation.

    abstract:IMPORTANCE:While monotherapy with biologic agents is effective for many patients with psoriasis, some patients require combination therapy. Evidence-based recommendations on combination therapy provide guidance for treating appropriately selected patients with psoriasis. OBJECTIVE:To make evidence-based, best-practice...

    journal_title:JAMA dermatology

    pub_type: 杂志文章,评审

    doi:10.1001/jamadermatol.2014.3456

    authors: Armstrong AW,Bagel J,Van Voorhees AS,Robertson AD,Yamauchi PS

    更新日期:2015-04-01 00:00:00

  • Lichen sclerosus with vaginal involvement: report of 2 cases and review of the literature.

    abstract:IMPORTANCE:Lichen sclerosus (LS) is an uncommon chronic inflammatory disease that most commonly affects anogenital skin of postmenopausal women. It typically manifests as atrophic white plaques, which may be accompanied by purpura or fissuring. Rarely, LS has been observed to affect mucosal tissues in the mouth and the...

    journal_title:JAMA dermatology

    pub_type: 杂志文章,评审

    doi:10.1001/jamadermatol.2013.4885

    authors: Zendell K,Edwards L

    更新日期:2013-10-01 00:00:00

  • Oral pigmentation in McCune-Albright syndrome.

    abstract:IMPORTANCE:The differential diagnosis for oral lentigines includes several syndromes with important associated systemic findings. McCune-Albright syndrome (MAS), a mosaic condition associated with café au lait pigmentation, is not typically considered a mucosal lentiginosis syndrome. The clinical phenotype of MAS is va...

    journal_title:JAMA dermatology

    pub_type: 杂志文章

    doi:10.1001/jamadermatol.2014.184

    authors: Pichard DC,Boyce AM,Collins MT,Cowen EW

    更新日期:2014-07-01 00:00:00

  • Prescribed Exercise With Compression vs Compression Alone in Treating Patients With Venous Leg Ulcers: A Systematic Review and Meta-analysis.

    abstract:Importance:Exercise is recommended as an adjuvant treatment for venous leg ulceration (VLU) to improve calf muscle pump function. However, the association of exercise with VLU healing has not been properly aggregated, and the effectiveness of different exercise interventions has not been characterized. Objective:To su...

    journal_title:JAMA dermatology

    pub_type: 杂志文章,meta分析

    doi:10.1001/jamadermatol.2018.3281

    authors: Jull A,Slark J,Parsons J

    更新日期:2018-11-01 00:00:00

  • Multiple epithelioid Spitz nevi or tumors with loss of BAP1 expression: a clue to a hereditary tumor syndrome.

    abstract:IMPORTANCE:Recently, a group of melanocytic tumors with loss of BAP1 expression has been described. The lesions may occur sporadically or as part of a familial cancer syndrome. They have distinct histopathologic features characterized by a nevus like silhouette and cytologic composition of large epithelioid melanocytes...

    journal_title:JAMA dermatology

    pub_type: 杂志文章

    doi:10.1001/jamadermatol.2013.1529

    authors: Busam KJ,Wanna M,Wiesner T

    更新日期:2013-03-01 00:00:00

  • Comparison of Dermatology and Allergy Guidelines for Atopic Dermatitis Management.

    abstract:IMPORTANCE:Atopic dermatitis (AD) is a common skin condition treated by dermatologists, allergists, pediatricians, and primary care physicians. Several treatment guidelines and therapeutic parameters exist for the management of this disease. Health care professionals may be unaware of guidelines created by specialty or...

    journal_title:JAMA dermatology

    pub_type: 杂志文章,评审

    doi:10.1001/jamadermatol.2015.0250

    authors: Mohan GC,Lio PA

    更新日期:2015-09-01 00:00:00

  • Sun Protection by Beach Umbrella vs Sunscreen With a High Sun Protection Factor: A Randomized Clinical Trial.

    abstract:Importance:Sun-protective behavior affects skin cancer prevention. Shade works by physically shielding skin from direct harmful UV rays; however, skin may still remain exposed to reflected and indirect UV rays. There is no current standard metric to evaluate shade for its effectiveness in sun protection, and there is i...

    journal_title:JAMA dermatology

    pub_type: 杂志文章,随机对照试验

    doi:10.1001/jamadermatol.2016.4922

    authors: Ou-Yang H,Jiang LI,Meyer K,Wang SQ,Farberg AS,Rigel DS

    更新日期:2017-03-01 00:00:00

  • Clinical Features of Neutrophilic Dermatosis Variants Resembling Necrotizing Fasciitis.

    abstract:Importance:Pyoderma gangrenosum and necrotizing Sweet syndrome are diagnostically challenging variants of neutrophilic dermatosis that can clinically mimic the cutaneous and systemic features of necrotizing fasciitis. Improved characterization of these rare variants is needed, as improper diagnosis may lead to inapprop...

    journal_title:JAMA dermatology

    pub_type: 杂志文章,多中心研究

    doi:10.1001/jamadermatol.2018.3890

    authors: Sanchez IM,Lowenstein S,Johnson KA,Babik J,Haag C,Keller JJ,Ortega-Loayza AG,Cohen J,McCalmont TH,Demer AM,Mansh MD,Hylwa SA,Liu J,Shinkai K

    更新日期:2019-01-01 00:00:00

  • Primary cutaneous mucinous carcinoma: a systematic review and meta-analysis of outcomes after surgery.

    abstract:IMPORTANCE:Evidence-based treatment guidelines are not available for primary cutaneous mucinous carcinoma (PCMC). OBJECTIVE:To assess outcomes associated with surgical treatment of PCMC. DATA SOURCES:MEDLINE, Cumulative Index to Nursing and Allied Health, and Embase from 1952 to 2010. Search terms were "primary cutan...

    journal_title:JAMA dermatology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1001/jamadermatol.2013.6006

    authors: Kamalpour L,Brindise RT,Nodzenski M,Bach DQ,Veledar E,Alam M

    更新日期:2014-04-01 00:00:00

  • Characteristics and associations of high-mitotic-rate melanoma.

    abstract:IMPORTANCE:Mitotic rate is now recognized as having independent prognostic significance in melanoma survival. However, its clinicopathologic associations have not been the focus of any previous study. OBJECTIVE:To identify a set of patient and tumor characteristics associated with high-mitotic-rate melanoma with the a...

    journal_title:JAMA dermatology

    pub_type: 杂志文章

    doi:10.1001/jamadermatol.2014.635

    authors: Shen S,Wolfe R,McLean CA,Haskett M,Kelly JW

    更新日期:2014-10-01 00:00:00

  • Reliability and Validity of Cutaneous Sarcoidosis Outcome Instruments Among Dermatologists, Pulmonologists, and Rheumatologists.

    abstract:Importance:Dermatologists, pulmonologists, and rheumatologists study and treat patients with sarcoidosis with cutaneous manifestations. The validity of cutaneous sarcoidosis outcome instruments for use across medical specialties remains unknown. Objective:To assess the reliability and validity of cutaneous sarcoidosis...

    journal_title:JAMA dermatology

    pub_type: 杂志文章

    doi:10.1001/jamadermatol.2015.2008

    authors: Yeung H,Farber S,Birnbaum BK,Dunham J,Ogdie A,Patterson KC,Payne AS,Porteous MK,Rossman MD,Sharim R,Takeshita J,Werth VP,Shin DB,Price S,Rosenbach M

    更新日期:2015-12-01 00:00:00

  • Association of Vitamin D Receptor Polymorphisms With the Risk of Nonmelanoma Skin Cancer in Adults.

    abstract:Importance:Protective effects of UV-B radiation against nonmelanoma skin cancer (NMSC) are exerted via signaling mechanisms involving the vitamin D receptor (VDR). Recent studies have examined single-nucleotide polymorphisms (SNPs) in the VDR, resulting in contradictory findings as to whether these polymorphisms increa...

    journal_title:JAMA dermatology

    pub_type: 杂志文章

    doi:10.1001/jamadermatol.2017.1976

    authors: Burns EM,Guroji P,Ahmad I,Nasr HM,Wang Y,Tamimi IA,Stiefel E,Abdelgawwad MS,Shaheen A,Muzaffar AF,Bush LM,Hurst CB,Griffin RL,Elmets CA,Yusuf N

    更新日期:2017-10-01 00:00:00

  • Hydroxychloroquine-induced pigmentation in patients with systemic lupus erythematosus: a case-control study.

    abstract:IMPORTANCE:Hydroxychloroquine-induced pigmentation is not a rare adverse effect. Our data support the hypothesis that hydroxychloroquine-induced pigmentation is secondary to ecchymosis or bruising. OBJECTIVE:To describe the clinical features and outcome of hydroxychloroquine (HCQ)-induced pigmentation in patients with...

    journal_title:JAMA dermatology

    pub_type: 杂志文章

    doi:10.1001/jamadermatol.2013.709

    authors: Jallouli M,Francès C,Piette JC,Huong du LT,Moguelet P,Factor C,Zahr N,Miyara M,Saadoun D,Mathian A,Haroche J,De Gennes C,Leroux G,Chapelon C,Wechsler B,Cacoub P,Amoura Z,Costedoat-Chalumeau N,Plaquenil LUpus Systemic

    更新日期:2013-08-01 00:00:00

  • Association of Resilience With Depression and Health-Related Quality of Life for Patients With Hidradenitis Suppurativa.

    abstract:Importance:Hidradenitis suppurativa (HS) places a significant burden on the health-related quality of life (HRQOL) of patients, many of whom have depression. Resilience can play a role in mitigating the negative stressors, such as the symptoms of HS, on patients' mental health. Objective:To investigate the correlation...

    journal_title:JAMA dermatology

    pub_type: 杂志文章,多中心研究

    doi:10.1001/jamadermatol.2017.3596

    authors: Kirby JS,Butt M,Esmann S,Jemec GBE

    更新日期:2017-12-01 00:00:00

  • Association Between Mediterranean Anti-inflammatory Dietary Profile and Severity of Psoriasis: Results From the NutriNet-Santé Cohort.

    abstract:Importance:Psoriasis is a chronic inflammatory disease. The Mediterranean diet has been shown to reduce chronic inflammation and has a positive effect on the risk of metabolic syndrome and cardiovascular events. Thus, we hypothesized a positive effect on the onset and/or severity of psoriasis. Objective:To assess the ...

    journal_title:JAMA dermatology

    pub_type: 杂志文章

    doi:10.1001/jamadermatol.2018.2127

    authors: Phan C,Touvier M,Kesse-Guyot E,Adjibade M,Hercberg S,Wolkenstein P,Chosidow O,Ezzedine K,Sbidian E

    更新日期:2018-09-01 00:00:00

  • Correlation Among Cancer Incidence and Mortality Rates and Internet Searches in the United States.

    abstract:Importance:Population-level disease metrics are critical to guide the distribution of resources and implementation of public health initiatives. Internet search data reflect population interest in health topics and may be an alternative metric of disease characteristics when traditional sources are lacking, such as in ...

    journal_title:JAMA dermatology

    pub_type: 杂志文章

    doi:10.1001/jamadermatol.2017.1870

    authors: Wehner MR,Nead KT,Linos E

    更新日期:2017-09-01 00:00:00

  • Assessment and Treatment Outcomes of Persistent Radiation-Induced Alopecia in Patients With Cancer.

    abstract:Importance:Persistent radiation-induced alopecia (pRIA) and its management have not been systematically described. Objective:To characterize pRIA in patients with primary central nervous system (CNS) tumors or head and neck sarcoma. Design, Setting, and Participants:A retrospective cohort study of patients from Janua...

    journal_title:JAMA dermatology

    pub_type: 杂志文章

    doi:10.1001/jamadermatol.2020.2127

    authors: Phillips GS,Freret ME,Friedman DN,Trelles S,Kukoyi O,Freites-Martinez A,Unger RH,Disa JJ,Wexler LH,Tinkle CL,Mechalakos JG,Dusza SW,Beal K,Wolden SL,Lacouture ME

    更新日期:2020-09-01 00:00:00

  • Validating 4 Staging Systems for Cutaneous Squamous Cell Carcinoma Using Population-Based Data: A Nested Case-Control Study.

    abstract:Importance:Cutaneous squamous cell carcinoma (cSCC) has metastatic potential, but the prognostic value of current staging systems in nonselected patients is uncertain. Objective:To assess the effect of risk factors for metastasis and to evaluate validity and usefulness of 4 staging systems for cSCC using population-ba...

    journal_title:JAMA dermatology

    pub_type: 杂志文章

    doi:10.1001/jamadermatol.2017.6428

    authors: Roscher I,Falk RS,Vos L,Clausen OPF,Helsing P,Gjersvik P,Robsahm TE

    更新日期:2018-04-01 00:00:00

  • Efficacy and Safety of Baricitinib Combined With Topical Corticosteroids for Treatment of Moderate to Severe Atopic Dermatitis: A Randomized Clinical Trial.

    abstract:Importance:Baricitinib, an oral selective Janus kinase 1 and 2 inhibitor, effectively reduced disease severity in moderate to severe atopic dermatitis (AD) in 2 phase 3 monotherapy studies. Objective:To assess the efficacy and safety of 4 mg and 2 mg of baricitinib in combination with background topical corticosteroid...

    journal_title:JAMA dermatology

    pub_type: 杂志文章

    doi:10.1001/jamadermatol.2020.3260

    authors: Reich K,Kabashima K,Peris K,Silverberg JI,Eichenfield LF,Bieber T,Kaszuba A,Kolodsick J,Yang FE,Gamalo M,Brinker DR,DeLozier AM,Janes JM,Nunes FP,Thyssen JP,Simpson EL

    更新日期:2020-12-01 00:00:00

  • Association of Sirolimus Use With Risk for Skin Cancer in a Mixed-Organ Cohort of Solid-Organ Transplant Recipients With a History of Cancer.

    abstract:IMPORTANCE:Solid-organ transplant recipients (OTRs) are at an increased risk for skin cancer. Prior studies have demonstrated a reduced incidence of skin cancer in renal OTRs treated with sirolimus. However, little information exists on the use of sirolimus for the prevention of skin cancer in nonrenal OTRs or those al...

    journal_title:JAMA dermatology

    pub_type: 杂志文章,多中心研究

    doi:10.1001/jamadermatol.2015.5548

    authors: Karia PS,Azzi JR,Heher EC,Hills VM,Schmults CD

    更新日期:2016-05-01 00:00:00

  • A Multicenter Cross-Sectional Study and Systematic Review of Necrobiotic Xanthogranuloma With Proposed Diagnostic Criteria.

    abstract:Importance:Necrobiotic xanthogranuloma (NXG) is a non-Langerhans cell histiocytosis classically associated with paraproteinemia attributable to plasma-cell dyscrasias or lymphoproliferative disorders. Despite the morbidity of NXG, the literature is limited to case reports and small studies, and diagnostic criteria are ...

    journal_title:JAMA dermatology

    pub_type: 杂志文章,多中心研究

    doi:10.1001/jamadermatol.2019.4221

    authors: Nelson CA,Zhong CS,Hashemi DA,Ashchyan HJ,Brown-Joel Z,Noe MH,Imadojemu S,Micheletti RG,Vleugels RA,Wanat KA,Rosenbach M,Mostaghimi A

    更新日期:2020-03-01 00:00:00

  • Dermatopulmonary Syndrome Associated With Anti-MDA5 Antibodies After Allogeneic Hematopoietic Stem Cell Transplantation.

    abstract:Importance:Chronic graft-vs-host-disease (cGVHD) after allogeneic stem cell transplantation (AHSCT) may resemble autoimmune diseases. Anti-MDA5 (melanoma differentiation-associated gene 5) dermatopulmonary syndrome is a subset of dermatomyositis defined by specific clinical features and detection of anti-MDA5-antibodie...

    journal_title:JAMA dermatology

    pub_type: 杂志文章

    doi:10.1001/jamadermatol.2016.3976

    authors: Lepelletier C,Bengoufa D,Lyes Z,de Masson A,Chasset F,Jachiet M,Michonneau D,Robin M,Peffault de Latour R,Sicre de Fontbrune F,Tandjaoui-Lambiotte Y,Bensussan A,Rybojad M,Tazi A,Bagot M,Socié G,Bergeron A,Bouaziz JD

    更新日期:2017-02-01 00:00:00