Psoriasis and the risk of diabetes mellitus: a systematic review and meta-analysis.

abstract：IMPORTANCE:Recently, a group of melanocytic tumors with loss of BAP1 expression has been described. The lesions may occur sporadically or as part of a familial cancer syndrome. They have distinct histopathologic features characterized by a nevus like silhouette and cytologic composition of large epithelioid melanocytes...

journal_title：JAMA dermatology

authors： Busam KJ,Wanna M,Wiesner T

更新日期：2013-03-01 00:00:00

abstract：Importance:The association between psoriasis and risk of cancer remains debatable. Objective:To evaluate the association and risk of cancer in patients with psoriasis or psoriatic arthritis, including risk of specific cancer subtypes. Data Sources:Two databases (PubMed and Embase) were screened from inception to Janu...

journal_title：JAMA dermatology

authors： Vaengebjerg S,Skov L,Egeberg A,Loft ND

更新日期：2020-04-01 00:00:00

abstract：Importance:Population-level disease metrics are critical to guide the distribution of resources and implementation of public health initiatives. Internet search data reflect population interest in health topics and may be an alternative metric of disease characteristics when traditional sources are lacking, such as in ...

journal_title：JAMA dermatology

authors： Wehner MR,Nead KT,Linos E

更新日期：2017-09-01 00:00:00

abstract：IMPORTANCE:Treatment outcomes depend on adherence to the prescribed regimen. Primary nonadherence refers to not obtaining and starting to take a prescribed medication. The frequency of primary nonadherence to acne treatment has not been well characterized. The complexity of multidrug acne regimens may add to this probl...

journal_title：JAMA dermatology

authors： Anderson KL,Dothard EH,Huang KE,Feldman SR

更新日期：2015-06-01 00:00:00

abstract：Importance:Hidradenitis suppurativa (HS) places a significant burden on the health-related quality of life (HRQOL) of patients, many of whom have depression. Resilience can play a role in mitigating the negative stressors, such as the symptoms of HS, on patients' mental health. Objective:To investigate the correlation...

journal_title：JAMA dermatology

authors： Kirby JS,Butt M,Esmann S,Jemec GBE

更新日期：2017-12-01 00:00:00

abstract：Importance:A phase 2 trial comparing talimogene laherparepvec plus ipilimumab vs ipilimumab monotherapy in patients with advanced unresectable melanoma found no differential benefit in progression-free survival (PFS) but noted objective response rates (ORRs) of 38.8% (38 of 98 patients) vs 18.0% (18 of 100 patients), r...

journal_title：JAMA dermatology

authors： Almutairi AR,Alkhatib NS,Oh M,Curiel-Lewandrowski C,Babiker HM,Cranmer LD,McBride A,Abraham I

更新日期：2019-01-01 00:00:00

abstract：IMPORTANCE:Pseudoaneurysm is a well-known complication of trauma and iatrogenic injury to the vasculature. We report 3 cases of postsurgical pseudoaneurysm after Mohs surgery. OBSERVATIONS:Three patients who underwent Mohs surgery for nonmelanoma skin cancers presented between 2 and 4 weeks after surgery with several ...

journal_title：JAMA dermatology

authors： Dunbar SW,Hurst EA

更新日期：2014-05-01 00:00:00

abstract：Importance:Although regression is commonly observed in cutaneous melanoma, it is uncertain whether it is associated with patient prognosis. Objective:To determine whether histologically confirmed regression was associated with better or worse survival in patients with primary cutaneous melanoma. Design, Setting, and ...

journal_title：JAMA dermatology

authors： El Sharouni MA,Aivazian K,Witkamp AJ,Sigurdsson V,van Gils CH,Scolyer RA,Thompson JF,van Diest PJ,Lo SN

更新日期：2020-12-23 00:00:00

abstract：IMPORTANCE:Hidradenitis suppurativa (HS) is a chronic cutaneous disease with acutely painful flares that require appropriate and timely treatment. OBJECTIVE:To assess how individuals with HS utilize medical care, especially emergency department (ED) care, a high-cost setting, and to describe the health care costs for ...

journal_title：JAMA dermatology

authors： Kirby JS,Miller JJ,Adams DR,Leslie D

更新日期：2014-09-01 00:00:00

abstract：Importance:Psoriasis is a chronic inflammatory disease. The Mediterranean diet has been shown to reduce chronic inflammation and has a positive effect on the risk of metabolic syndrome and cardiovascular events. Thus, we hypothesized a positive effect on the onset and/or severity of psoriasis. Objective:To assess the ...

journal_title：JAMA dermatology

authors： Phan C,Touvier M,Kesse-Guyot E,Adjibade M,Hercberg S,Wolkenstein P,Chosidow O,Ezzedine K,Sbidian E

更新日期：2018-09-01 00:00:00

abstract：IMPORTANCE:Cryolipolysis is the noninvasive reduction of fat with localized cutaneous cooling. Since initial introduction, over 650,000 cryolipolysis treatment cycles have been performed worldwide. We present a previously unreported, rare adverse effect following cryolipolysis: paradoxical adipose hyperplasia. OBSERVA...

journal_title：JAMA dermatology

authors： Jalian HR,Avram MM,Garibyan L,Mihm MC,Anderson RR

更新日期：2014-03-01 00:00:00

abstract：IMPORTANCE:Although cutaneous warts are common lesions, full remission is not always achieved with conventional therapies. Laser modalities including carbon dioxide (CO2), erbium:yttrium-aluminum-garnet (Er:YAG), pulsed dye (PDL), and Nd:YAG have been investigated as alternative treatments for warts. OBJECTIVE:To revi...

journal_title：JAMA dermatology

authors： Nguyen J,Korta DZ,Chapman LW,Kelly KM

更新日期：2016-09-01 00:00:00

abstract：Importance:Baricitinib, an oral selective Janus kinase 1 and 2 inhibitor, effectively reduced disease severity in moderate to severe atopic dermatitis (AD) in 2 phase 3 monotherapy studies. Objective:To assess the efficacy and safety of 4 mg and 2 mg of baricitinib in combination with background topical corticosteroid...

journal_title：JAMA dermatology

authors： Reich K,Kabashima K,Peris K,Silverberg JI,Eichenfield LF,Bieber T,Kaszuba A,Kolodsick J,Yang FE,Gamalo M,Brinker DR,DeLozier AM,Janes JM,Nunes FP,Thyssen JP,Simpson EL

更新日期：2020-12-01 00:00:00

abstract：IMPORTANCE:Sarcoidosis is a chronic granulomatous disease for which there are limited therapeutic options. This is the first randomized, placebo-controlled study to demonstrate that antimycobacterial therapy reduces lesion diameter and disease severity among patients with chronic cutaneous sarcoidosis. OBJECTIVE:To ev...

journal_title：JAMA dermatology

authors： Drake WP,Oswald-Richter K,Richmond BW,Isom J,Burke VE,Algood H,Braun N,Taylor T,Pandit KV,Aboud C,Yu C,Kaminski N,Boyd AS,King LE

更新日期：2013-09-01 00:00:00

abstract：IMPORTANCE:Lichen sclerosus (LS) is an uncommon chronic inflammatory disease that most commonly affects anogenital skin of postmenopausal women. It typically manifests as atrophic white plaques, which may be accompanied by purpura or fissuring. Rarely, LS has been observed to affect mucosal tissues in the mouth and the...

journal_title：JAMA dermatology

authors： Zendell K,Edwards L

更新日期：2013-10-01 00:00:00

abstract：Importance:Patients with vascular malformations (VAMs) and vascular overgrowth syndromes have lower health-related quality of life (HRQoL) attributable to social stigmatization, poor mental health, severity, and pain. However, the factors that contribute to this decreased HRQoL are not clear. Objective:To perform a sy...

journal_title：JAMA dermatology

authors： Nguyen HL,Bonadurer GF 3rd,Tollefson MM

更新日期：2018-06-01 00:00:00

abstract：IMPORTANCE:Primary cutaneous diffuse large B-cell lymphoma, leg type (PCDLBCL-LT), occurs in elderly patients and has been considered as a lymphoma with a poor prognosis, with estimated 5-year specific survival rates of approximately 50%. The hypothesis of an improvement in prognosis over time has not been studied. OB...

journal_title：JAMA dermatology

authors： Grange F,Joly P,Barbe C,Bagot M,Dalle S,Ingen-Housz-Oro S,Maubec E,D'Incan M,Ram-Wolff C,Dalac S,Templier I,Esteve E,Quereux G,Machet L,Leduc M,Dereure O,Laroche L,Saiag P,Vergier B,Beylot-Barry M

更新日期：2014-05-01 00:00:00

abstract：IMPORTANCE:Describing the relationship between the availability of free prescription drug samples and dermatologists' prescribing patterns on a national scale can help inform policy guidelines on the use of free samples in a physician's office. OBJECTIVES:To investigate the relationships between free drug samples and ...

journal_title：JAMA dermatology

authors： Hurley MP,Stafford RS,Lane AT

更新日期：2014-05-01 00:00:00

abstract：Importance:Staged excision of lentigo maligna (LM) often requires multiple stages and can result in significant cosmetic morbidity. Imiquimod cream has been used off-label as monotherapy in the treatment of LM and may be used in the neoadjuvant setting prior to staged excision as a strategy to reduce the size of the su...

journal_title：JAMA dermatology

authors： Donigan JM,Hyde MA,Goldgar DE,Hadley ML,Bowling M,Bowen GM

更新日期：2018-08-01 00:00:00

abstract：Importance:Systemic and inhaled corticosteroids negatively affect bone remodeling and cause osteoporosis and bone fracture when given continuously or in high doses. However, risk of osteoporosis and major osteoporotic fracture (MOF) after application of topical corticosteroids (TCSs) is largely unexplored. Objective:T...

journal_title：JAMA dermatology

authors： Egeberg A,Schwarz P,Harsløf T,Andersen YMF,Pottegård A,Hallas J,Thyssen JP

更新日期：2021-01-20 00:00:00

abstract：Importance:Necrobiotic xanthogranuloma (NXG) is a non-Langerhans cell histiocytosis classically associated with paraproteinemia attributable to plasma-cell dyscrasias or lymphoproliferative disorders. Despite the morbidity of NXG, the literature is limited to case reports and small studies, and diagnostic criteria are ...

journal_title：JAMA dermatology

authors： Nelson CA,Zhong CS,Hashemi DA,Ashchyan HJ,Brown-Joel Z,Noe MH,Imadojemu S,Micheletti RG,Vleugels RA,Wanat KA,Rosenbach M,Mostaghimi A

更新日期：2020-03-01 00:00:00

abstract：IMPORTANCE:Telaprevir, combined with pegylated interferon alfa and ribavirin, is an efficacious approach to treat hepatitis C virus infection. A morbilliform eruption associated with telaprevir is a common adverse effect experienced by patients. Current guidelines mandate telaprevir discontinuation in any patient with ...

journal_title：JAMA dermatology

authors： Strazzula L,Pratt DS,Zardas J,Chung RT,Thiim M,Kroshinsky D

更新日期：2014-07-01 00:00:00

abstract：Clinical Question:Which treatments have been shown to be effective in randomized clinical trials (RCTs) for hidradenitis suppurativa (HS) in adults? Bottom Line:There is high-quality evidence of benefit from adalimumab given weekly, while every other week dosing is ineffective, with reductions in Dermatology Life Qual...

journal_title：JAMA dermatology

authors： Ingram JR

更新日期：2017-05-01 00:00:00

abstract：Importance:Use of systemic therapies for moderate to severe psoriasis in children is increasing, but comparative data on their use and toxicities are limited. Objective:To assess patterns of use and relative risks of systemic agents for moderate to severe psoriasis in children. Design, Setting, and Participants:A ret...

journal_title：JAMA dermatology

authors： Bronckers IMGJ,Seyger MMB,West DP,Lara-Corrales I,Tollefson M,Tom WL,Hogeling M,Belazarian L,Zachariae C,Mahé E,Siegfried E,Philipp S,Szalai Z,Vleugels RA,Holland K,Murphy R,Baselga E,Cordoro K,Lambert J,Alexopoulos

更新日期：2017-11-01 00:00:00

abstract：IMPORTANCE:Basal cell carcinomas (BCCs) are diagnosed by clinical evaluation, which can include dermoscopic evaluation, biopsy, and histopathologic examination. Recent translation of multiphoton microscopy (MPM) to clinical practice raises the possibility of noninvasive, label-free in vivo imaging of BCCs that could re...

journal_title：JAMA dermatology

authors： Balu M,Zachary CB,Harris RM,Krasieva TB,König K,Tromberg BJ,Kelly KM

更新日期：2015-10-01 00:00:00

abstract：Importance:Melanoma treatment has been revolutionized with the development of immune-based therapies that offer durable clinical responses in a subset of patients. Clinical outcomes after treatment by immunotherapy can be influenced by the host's immune system. The immune system is modified with age by age-related immu...

journal_title：JAMA dermatology

authors： Perier-Muzet M,Gatt E,Péron J,Falandry C,Amini-Adlé M,Thomas L,Dalle S,Boespflug A

更新日期：2018-01-01 00:00:00

abstract：Importance:Persistent radiation-induced alopecia (pRIA) and its management have not been systematically described. Objective:To characterize pRIA in patients with primary central nervous system (CNS) tumors or head and neck sarcoma. Design, Setting, and Participants:A retrospective cohort study of patients from Janua...

journal_title：JAMA dermatology

authors： Phillips GS,Freret ME,Friedman DN,Trelles S,Kukoyi O,Freites-Martinez A,Unger RH,Disa JJ,Wexler LH,Tinkle CL,Mechalakos JG,Dusza SW,Beal K,Wolden SL,Lacouture ME

更新日期：2020-09-01 00:00:00

abstract：Importance:High-cost biologic therapies have transformed the management of immune-mediated inflammatory diseases. To optimize outcomes and reduce costs, dose adjustment informed by measurement of circulating drug levels has been shown to be effective in various settings. However, limited evidence exists for this approa...

journal_title：JAMA dermatology

authors： Tsakok T,Wilson N,Dand N,Loeff FC,Bloem K,Baudry D,Duckworth M,Pan S,Pushpa-Rajah A,Standing JF,de Vries A,Alsharqi A,Becher G,Murphy R,Wahie S,Wright A,Griffiths CEM,Reynolds NJ,Barker J,Warren RB,Burden AD,Ris

更新日期：2019-09-18 00:00:00

abstract：IMPORTANCE:While monotherapy with biologic agents is effective for many patients with psoriasis, some patients require combination therapy. Evidence-based recommendations on combination therapy provide guidance for treating appropriately selected patients with psoriasis. OBJECTIVE:To make evidence-based, best-practice...

journal_title：JAMA dermatology

authors： Armstrong AW,Bagel J,Van Voorhees AS,Robertson AD,Yamauchi PS

更新日期：2015-04-01 00:00:00

abstract：Importance:The US Food and Drug Administration approves Class III medical devices via the premarket approval pathway, often requiring clinical data on safety and efficacy. Manufacturers can submit incremental device changes via supplemental applications, which are not subjected to such vetting measures and can cause un...

journal_title：JAMA dermatology

authors： Ezaldein HH,Scott JF,Yin ES,Ventura A,DeRuyter NP,Leffell DJ

更新日期：2018-03-01 00:00:00