Association of Immunotherapy With Overall Survival in Elderly Patients With Melanoma.

abstract：Importance:Inflammatory dermatoses of the lower extremity are often misdiagnosed as cellulitis (aka "pseudocellulitis") and treated with antibiotics and/or hospitalization. There is limited data on the cost and complications from misdiagnosed cellulitis. Objective:To characterize the national health care burden of mis...

journal_title：JAMA dermatology

authors： Weng QY,Raff AB,Cohen JM,Gunasekera N,Okhovat JP,Vedak P,Joyce C,Kroshinsky D,Mostaghimi A

更新日期：2017-02-01 00:00:00

abstract：IMPORTANCE:Although cutaneous warts are common lesions, full remission is not always achieved with conventional therapies. Laser modalities including carbon dioxide (CO2), erbium:yttrium-aluminum-garnet (Er:YAG), pulsed dye (PDL), and Nd:YAG have been investigated as alternative treatments for warts. OBJECTIVE:To revi...

journal_title：JAMA dermatology

authors： Nguyen J,Korta DZ,Chapman LW,Kelly KM

更新日期：2016-09-01 00:00:00

abstract：Importance:The dupilumab regimen of 300 mg every 2 weeks is approved for uncontrolled, moderate to severe atopic dermatitis (AD). Objective:To assess the efficacy and safety of different dupilumab regimens in maintaining response after 16 weeks of initial treatment. Design, Setting, and Participants:The Study to Conf...

journal_title：JAMA dermatology

authors： Worm M,Simpson EL,Thaçi D,Bissonnette R,Lacour JP,Beissert S,Kawashima M,Ferrándiz C,Smith CH,Beck LA,Chan KC,Chen Z,Akinlade B,Hultsch T,Staudinger H,Gadkari A,Eckert L,Davis JD,Rajadhyaksha M,Graham NMH,Pirozzi

更新日期：2020-02-01 00:00:00

abstract：Importance:Advanced practice professionals (APPs) such as nurse practitioners and physician assistants independently perform a large number and variety of dermatologic procedures, but little is known about how the number and scope of these procedures have changed over time. Objective:To examine the trends in scope and...

journal_title：JAMA dermatology

authors： Zhang M,Zippin J,Kaffenberger B

更新日期：2018-09-01 00:00:00

abstract：Importance:Use of systemic therapies for moderate to severe psoriasis in children is increasing, but comparative data on their use and toxicities are limited. Objective:To assess patterns of use and relative risks of systemic agents for moderate to severe psoriasis in children. Design, Setting, and Participants:A ret...

journal_title：JAMA dermatology

authors： Bronckers IMGJ,Seyger MMB,West DP,Lara-Corrales I,Tollefson M,Tom WL,Hogeling M,Belazarian L,Zachariae C,Mahé E,Siegfried E,Philipp S,Szalai Z,Vleugels RA,Holland K,Murphy R,Baselga E,Cordoro K,Lambert J,Alexopoulos

更新日期：2017-11-01 00:00:00

abstract：Importance:Exercise is recommended as an adjuvant treatment for venous leg ulceration (VLU) to improve calf muscle pump function. However, the association of exercise with VLU healing has not been properly aggregated, and the effectiveness of different exercise interventions has not been characterized. Objective:To su...

journal_title：JAMA dermatology

authors： Jull A,Slark J,Parsons J

更新日期：2018-11-01 00:00:00

abstract：Importance:Systemic and inhaled corticosteroids negatively affect bone remodeling and cause osteoporosis and bone fracture when given continuously or in high doses. However, risk of osteoporosis and major osteoporotic fracture (MOF) after application of topical corticosteroids (TCSs) is largely unexplored. Objective:T...

journal_title：JAMA dermatology

authors： Egeberg A,Schwarz P,Harsløf T,Andersen YMF,Pottegård A,Hallas J,Thyssen JP

更新日期：2021-01-20 00:00:00

abstract：Importance:Patients with vascular malformations (VAMs) and vascular overgrowth syndromes have lower health-related quality of life (HRQoL) attributable to social stigmatization, poor mental health, severity, and pain. However, the factors that contribute to this decreased HRQoL are not clear. Objective:To perform a sy...

journal_title：JAMA dermatology

authors： Nguyen HL,Bonadurer GF 3rd,Tollefson MM

更新日期：2018-06-01 00:00:00

abstract：Importance:Melanoma risk factors and incidence in renal transplant recipients can inform decision making for both patients and clinicians. Objective:To determine risk factors and characteristics of renal transplant recipients who develop melanoma. Design, Setting, and Participants:This cohort study of a large nationa...

journal_title：JAMA dermatology

authors： Ascha M,Ascha MS,Tanenbaum J,Bordeaux JS

更新日期：2017-11-01 00:00:00

abstract：IMPORTANCE:Hidradenitis suppurativa (HS) is a chronic cutaneous disease with acutely painful flares that require appropriate and timely treatment. OBJECTIVE:To assess how individuals with HS utilize medical care, especially emergency department (ED) care, a high-cost setting, and to describe the health care costs for ...

journal_title：JAMA dermatology

authors： Kirby JS,Miller JJ,Adams DR,Leslie D

更新日期：2014-09-01 00:00:00

abstract：Importance:Staged excision of lentigo maligna (LM) often requires multiple stages and can result in significant cosmetic morbidity. Imiquimod cream has been used off-label as monotherapy in the treatment of LM and may be used in the neoadjuvant setting prior to staged excision as a strategy to reduce the size of the su...

journal_title：JAMA dermatology

authors： Donigan JM,Hyde MA,Goldgar DE,Hadley ML,Bowling M,Bowen GM

更新日期：2018-08-01 00:00:00

abstract：Importance:Protective effects of UV-B radiation against nonmelanoma skin cancer (NMSC) are exerted via signaling mechanisms involving the vitamin D receptor (VDR). Recent studies have examined single-nucleotide polymorphisms (SNPs) in the VDR, resulting in contradictory findings as to whether these polymorphisms increa...

journal_title：JAMA dermatology

authors： Burns EM,Guroji P,Ahmad I,Nasr HM,Wang Y,Tamimi IA,Stiefel E,Abdelgawwad MS,Shaheen A,Muzaffar AF,Bush LM,Hurst CB,Griffin RL,Elmets CA,Yusuf N

更新日期：2017-10-01 00:00:00

abstract：Importance:Pyoderma gangrenosum and necrotizing Sweet syndrome are diagnostically challenging variants of neutrophilic dermatosis that can clinically mimic the cutaneous and systemic features of necrotizing fasciitis. Improved characterization of these rare variants is needed, as improper diagnosis may lead to inapprop...

journal_title：JAMA dermatology

authors： Sanchez IM,Lowenstein S,Johnson KA,Babik J,Haag C,Keller JJ,Ortega-Loayza AG,Cohen J,McCalmont TH,Demer AM,Mansh MD,Hylwa SA,Liu J,Shinkai K

更新日期：2019-01-01 00:00:00

abstract：Importance:Erythromelalgia is a clinical diagnosis based on intermittent warmth, erythema, and pain in the distal extremities. One problem facing physicians is how to objectively test for this disease. Given that other painful conditions of the distal extremities (ie, neuropathy related to human immunodeficiency virus,...

journal_title：JAMA dermatology

authors： Mantyh WG,Dyck PJB,Dyck PJ,Engelstad JK,Litchy WJ,Sandroni P,Davis MDP

更新日期：2017-02-01 00:00:00

abstract：IMPORTANCE:Atopic dermatitis (AD) is a common skin condition treated by dermatologists, allergists, pediatricians, and primary care physicians. Several treatment guidelines and therapeutic parameters exist for the management of this disease. Health care professionals may be unaware of guidelines created by specialty or...

journal_title：JAMA dermatology

authors： Mohan GC,Lio PA

更新日期：2015-09-01 00:00:00

abstract：IMPORTANCE:Cryolipolysis is the noninvasive reduction of fat with localized cutaneous cooling. Since initial introduction, over 650,000 cryolipolysis treatment cycles have been performed worldwide. We present a previously unreported, rare adverse effect following cryolipolysis: paradoxical adipose hyperplasia. OBSERVA...

journal_title：JAMA dermatology

authors： Jalian HR,Avram MM,Garibyan L,Mihm MC,Anderson RR

更新日期：2014-03-01 00:00:00

abstract：IMPORTANCE:Worse survival among patients with melanoma has been demonstrated in middle-aged and older men compared with women, but few studies have explored survival differences by sex in adolescents and young adults, in whom melanoma is the third most common cancer. Focusing on sex disparities in survival among younge...

journal_title：JAMA dermatology

authors： Gamba CS,Clarke CA,Keegan TH,Tao L,Swetter SM

更新日期：2013-08-01 00:00:00

abstract：IMPORTANCE:How complications associated with chronic venous insufficiency (CVI) develop is not clear. The central source of the complications is likely a dysfunction of the calf muscle pump, which includes veins and their valves, the gastrocnemius and other lower leg and foot muscles as well as the nerves supplying the...

journal_title：JAMA dermatology

authors： Yim E,Vivas A,Maderal A,Kirsner RS

更新日期：2014-04-01 00:00:00

abstract：Importance:In the US, incidence of and mortality due to anal carcinoma are rising faster than for most other cancers. Identifying populations who have a higher risk of developing anal cancers is critical to target preventive interventions. Objective:To assess the risk of developing anal carcinoma in adults living with...

journal_title：JAMA dermatology

authors： Arnold JD,Byrne ME,Monroe AK,Abbott SE,District of Columbia Cohort Executive Committee.

更新日期：2021-01-13 00:00:00

abstract：IMPORTANCE:Mitotic rate is now recognized as having independent prognostic significance in melanoma survival. However, its clinicopathologic associations have not been the focus of any previous study. OBJECTIVE:To identify a set of patient and tumor characteristics associated with high-mitotic-rate melanoma with the a...

journal_title：JAMA dermatology

authors： Shen S,Wolfe R,McLean CA,Haskett M,Kelly JW

更新日期：2014-10-01 00:00:00

abstract：Clinical Question:Which treatments have been shown to be effective in randomized clinical trials (RCTs) for hidradenitis suppurativa (HS) in adults? Bottom Line:There is high-quality evidence of benefit from adalimumab given weekly, while every other week dosing is ineffective, with reductions in Dermatology Life Qual...

journal_title：JAMA dermatology

authors： Ingram JR

更新日期：2017-05-01 00:00:00

abstract：IMPORTANCE:Recently, a group of melanocytic tumors with loss of BAP1 expression has been described. The lesions may occur sporadically or as part of a familial cancer syndrome. They have distinct histopathologic features characterized by a nevus like silhouette and cytologic composition of large epithelioid melanocytes...

journal_title：JAMA dermatology

authors： Busam KJ,Wanna M,Wiesner T

更新日期：2013-03-01 00:00:00

abstract：Importance:There is limited information regarding the influence of patient demographics, tumor characteristics, and treatment type on the survival of patients with dermatofibrosarcoma protuberans (DFSP). Objective:To assess prognostic factors and to evaluate the influence of treatment modality on overall survival of p...

journal_title：JAMA dermatology

authors： Criscito MC,Martires KJ,Stein JA

更新日期：2016-12-01 00:00:00

abstract：IMPORTANCE:Evidence-based treatment guidelines are not available for primary cutaneous mucinous carcinoma (PCMC). OBJECTIVE:To assess outcomes associated with surgical treatment of PCMC. DATA SOURCES:MEDLINE, Cumulative Index to Nursing and Allied Health, and Embase from 1952 to 2010. Search terms were "primary cutan...

journal_title：JAMA dermatology

authors： Kamalpour L,Brindise RT,Nodzenski M,Bach DQ,Veledar E,Alam M

更新日期：2014-04-01 00:00:00

abstract：Importance:Persistent radiation-induced alopecia (pRIA) and its management have not been systematically described. Objective:To characterize pRIA in patients with primary central nervous system (CNS) tumors or head and neck sarcoma. Design, Setting, and Participants:A retrospective cohort study of patients from Janua...

journal_title：JAMA dermatology

authors： Phillips GS,Freret ME,Friedman DN,Trelles S,Kukoyi O,Freites-Martinez A,Unger RH,Disa JJ,Wexler LH,Tinkle CL,Mechalakos JG,Dusza SW,Beal K,Wolden SL,Lacouture ME

更新日期：2020-09-01 00:00:00

abstract：Importance:Pubic hair grooming is a common practice that can lead to injury and morbidity. Objective:To identify demographic and behavioral risk factors associated with pubic hair grooming-related injuries to characterize individuals with high risk of injury and develop recommendations for safe grooming practices. De...

journal_title：JAMA dermatology

authors： Truesdale MD,Osterberg EC,Gaither TW,Awad MA,Elmer-DeWitt MA,Sutcliffe S,Allen I,Breyer BN

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:To compare the prevalence and incidence of type 2 diabetes mellitus between patients with psoriasis and those without psoriasis. DATA SOURCES:MEDLINE, EMBASE, and Cochrane Database of Systematic Reviews between January 1, 1980, and January 1, 2012. STUDY SELECTION:Observational (cohort, case-control, and cr...

journal_title：JAMA dermatology

authors： Armstrong AW,Harskamp CT,Armstrong EJ

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVES:To calculate sunbed use prevalence rates, to investigate the motivations for tanning, and to identify typical target groups for interventions to prevent skin cancer. DESIGN:Cross-sectional, representative, population-based study, primary analysis of the SUN-Study 2012 (Sunbed-Use: Needs for Action-Study). ...

journal_title：JAMA dermatology

authors： Schneider S,Diehl K,Bock C,Schlüter M,Breitbart EW,Volkmer B,Greinert R

更新日期：2013-01-01 00:00:00

abstract：Importance:How patients' mental health is associated with their satisfaction with physicians is rarely studied among adults with skin conditions. Objective:To examine the association between mental health comorbidities in patients with psoriasis and their satisfaction with physicians. Design, Setting, and Participant...

journal_title：JAMA dermatology

authors： Read C,Armstrong AW

更新日期：2020-07-01 00:00:00

abstract：Importance:Psoriasis of the scalp, palms and/or soles, and nails is challenging to treat. Objective:To evaluate the effect of guselkumab on psoriasis in specific body regions. Design, Setting, and Participants:VOYAGE 1 and VOYAGE 2 were, double-blind, placebo- and adalimumab-controlled studies of guselkumab conducted...

journal_title：JAMA dermatology

authors： Foley P,Gordon K,Griffiths CEM,Wasfi Y,Randazzo B,Song M,Li S,Shen YK,Blauvelt A

更新日期：2018-06-01 00:00:00