Paradoxical adipose hyperplasia after cryolipolysis.

abstract：IMPORTANCE:Telaprevir, combined with pegylated interferon alfa and ribavirin, is an efficacious approach to treat hepatitis C virus infection. A morbilliform eruption associated with telaprevir is a common adverse effect experienced by patients. Current guidelines mandate telaprevir discontinuation in any patient with ...

journal_title：JAMA dermatology

authors： Strazzula L,Pratt DS,Zardas J,Chung RT,Thiim M,Kroshinsky D

更新日期：2014-07-01 00:00:00

abstract：IMPORTANCE:Purse-string suture is a closure method that purportedly reduces the scar area compared with second intention healing. Randomized clinical trials comparing these 2 methods appear to be limited or absent. OBJECTIVE:To determine if purse-string suture improves cosmetic outcome, healing time, and scar to defec...

journal_title：JAMA dermatology

authors： Joo J,Custis T,Armstrong AW,King TH,Omlin K,Kappel ST,Eisen DB

更新日期：2015-03-01 00:00:00

abstract：Importance:Erythromelalgia is a clinical diagnosis based on intermittent warmth, erythema, and pain in the distal extremities. One problem facing physicians is how to objectively test for this disease. Given that other painful conditions of the distal extremities (ie, neuropathy related to human immunodeficiency virus,...

journal_title：JAMA dermatology

authors： Mantyh WG,Dyck PJB,Dyck PJ,Engelstad JK,Litchy WJ,Sandroni P,Davis MDP

更新日期：2017-02-01 00:00:00

abstract：IMPORTANCE:While monotherapy with biologic agents is effective for many patients with psoriasis, some patients require combination therapy. Evidence-based recommendations on combination therapy provide guidance for treating appropriately selected patients with psoriasis. OBJECTIVE:To make evidence-based, best-practice...

journal_title：JAMA dermatology

authors： Armstrong AW,Bagel J,Van Voorhees AS,Robertson AD,Yamauchi PS

更新日期：2015-04-01 00:00:00

abstract：Importance:In the US, incidence of and mortality due to anal carcinoma are rising faster than for most other cancers. Identifying populations who have a higher risk of developing anal cancers is critical to target preventive interventions. Objective:To assess the risk of developing anal carcinoma in adults living with...

journal_title：JAMA dermatology

authors： Arnold JD,Byrne ME,Monroe AK,Abbott SE,District of Columbia Cohort Executive Committee.

更新日期：2021-01-13 00:00:00

abstract：Importance:The risk for skin cancer has been well characterized in white organ transplant recipients (OTRs); however, most patients on the waiting list for organ transplant in the United States are nonwhite. Little is known about cutaneous disease and skin cancer risk in this OTR population. Objective:To compare the i...

journal_title：JAMA dermatology

authors： Chung CL,Nadhan KS,Shaver CM,Ogrich LM,Abdelmalek M,Cusack CA,Malat GE,Pritchett EN,Doyle A

更新日期：2017-06-01 00:00:00

abstract：Importance:Pyoderma gangrenosum and necrotizing Sweet syndrome are diagnostically challenging variants of neutrophilic dermatosis that can clinically mimic the cutaneous and systemic features of necrotizing fasciitis. Improved characterization of these rare variants is needed, as improper diagnosis may lead to inapprop...

journal_title：JAMA dermatology

authors： Sanchez IM,Lowenstein S,Johnson KA,Babik J,Haag C,Keller JJ,Ortega-Loayza AG,Cohen J,McCalmont TH,Demer AM,Mansh MD,Hylwa SA,Liu J,Shinkai K

更新日期：2019-01-01 00:00:00

abstract：IMPORTANCE:Atopic dermatitis (AD) is a common skin condition treated by dermatologists, allergists, pediatricians, and primary care physicians. Several treatment guidelines and therapeutic parameters exist for the management of this disease. Health care professionals may be unaware of guidelines created by specialty or...

journal_title：JAMA dermatology

authors： Mohan GC,Lio PA

更新日期：2015-09-01 00:00:00

abstract：Importance:Chronic urticaria (CU) affects 0.1% to 0.3% of children. Most cases have no identifiable trigger and are classified as chronic spontaneous urticaria (CSU). At least half of patients with CSU may have an autoimmune etiology that can be determined in vitro using the basophil activation test (BAT). While 30% to...

journal_title：JAMA dermatology

authors： Netchiporouk E,Sasseville D,Moreau L,Habel Y,Rahme E,Ben-Shoshan M

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Immune reconstitution inflammatory syndrome (IRIS) is a phenomenon initially described in patients with human immunodeficiency virus. Upon initiation of combination antiretroviral therapy, recovery of cellular immunity triggers inflammation to a preexisting infection or antigen that causes paradoxical worsen...

journal_title：JAMA dermatology

authors： Scharschmidt TC,Amerson EH,Rosenberg OS,Jacobs RA,McCalmont TH,Shinkai K

更新日期：2013-01-01 00:00:00

abstract：Importance:The US Food and Drug Administration approves Class III medical devices via the premarket approval pathway, often requiring clinical data on safety and efficacy. Manufacturers can submit incremental device changes via supplemental applications, which are not subjected to such vetting measures and can cause un...

journal_title：JAMA dermatology

authors： Ezaldein HH,Scott JF,Yin ES,Ventura A,DeRuyter NP,Leffell DJ

更新日期：2018-03-01 00:00:00

abstract：Importance:Baricitinib, an oral selective Janus kinase 1 and 2 inhibitor, effectively reduced disease severity in moderate to severe atopic dermatitis (AD) in 2 phase 3 monotherapy studies. Objective:To assess the efficacy and safety of 4 mg and 2 mg of baricitinib in combination with background topical corticosteroid...

journal_title：JAMA dermatology

authors： Reich K,Kabashima K,Peris K,Silverberg JI,Eichenfield LF,Bieber T,Kaszuba A,Kolodsick J,Yang FE,Gamalo M,Brinker DR,DeLozier AM,Janes JM,Nunes FP,Thyssen JP,Simpson EL

更新日期：2020-12-01 00:00:00

abstract：IMPORTANCE:Apart from the atypical mole phenotype, development of new melanocytic nevi in older individuals is uncommon and considered worrisome for melanoma. We performed a retrospective case series in a Veterans Affairs population from 1991 to 2013 to characterize blue nevi (BN) by patient age at biopsy, location, se...

journal_title：JAMA dermatology

authors： Cabral ES,Chen FW,Egbert BM,Swetter SM

更新日期：2014-08-01 00:00:00

abstract：IMPORTANCE:Mobile smartphones are rapidly emerging as an effective means of communicating with many Americans. Using mobile applications (apps), they can access remote databases, track time and location, and integrate user input to provide tailored health information. OBJECTIVE:A smartphone mobile app providing person...

journal_title：JAMA dermatology

authors： Buller DB,Berwick M,Lantz K,Buller MK,Shane J,Kane I,Liu X

更新日期：2015-05-01 00:00:00

abstract：IMPORTANCE:Nevi are among the strongest risk factors for melanoma. However, little is known about the association of many total nevi (TN) or atypical nevi (AN) with tumor thickness. OBJECTIVES:To examine the association between age and the number of TN and AN and to explore whether there was a relationship between TN ...

journal_title：JAMA dermatology

authors： Geller AC,Mayer JE,Sober AJ,Miller DR,Argenziano G,Johnson TM,Swetter SM

更新日期：2016-04-01 00:00:00

abstract：IMPORTANCE:Hidradenitis suppurativa (HS) is a chronic cutaneous disease with acutely painful flares that require appropriate and timely treatment. OBJECTIVE:To assess how individuals with HS utilize medical care, especially emergency department (ED) care, a high-cost setting, and to describe the health care costs for ...

journal_title：JAMA dermatology

authors： Kirby JS,Miller JJ,Adams DR,Leslie D

更新日期：2014-09-01 00:00:00

abstract：Importance:Dermatologists, pulmonologists, and rheumatologists study and treat patients with sarcoidosis with cutaneous manifestations. The validity of cutaneous sarcoidosis outcome instruments for use across medical specialties remains unknown. Objective:To assess the reliability and validity of cutaneous sarcoidosis...

journal_title：JAMA dermatology

authors： Yeung H,Farber S,Birnbaum BK,Dunham J,Ogdie A,Patterson KC,Payne AS,Porteous MK,Rossman MD,Sharim R,Takeshita J,Werth VP,Shin DB,Price S,Rosenbach M

更新日期：2015-12-01 00:00:00

abstract：IMPORTANCE:Describing the relationship between the availability of free prescription drug samples and dermatologists' prescribing patterns on a national scale can help inform policy guidelines on the use of free samples in a physician's office. OBJECTIVES:To investigate the relationships between free drug samples and ...

journal_title：JAMA dermatology

authors： Hurley MP,Stafford RS,Lane AT

更新日期：2014-05-01 00:00:00

abstract：Importance:The dupilumab regimen of 300 mg every 2 weeks is approved for uncontrolled, moderate to severe atopic dermatitis (AD). Objective:To assess the efficacy and safety of different dupilumab regimens in maintaining response after 16 weeks of initial treatment. Design, Setting, and Participants:The Study to Conf...

journal_title：JAMA dermatology

authors： Worm M,Simpson EL,Thaçi D,Bissonnette R,Lacour JP,Beissert S,Kawashima M,Ferrándiz C,Smith CH,Beck LA,Chan KC,Chen Z,Akinlade B,Hultsch T,Staudinger H,Gadkari A,Eckert L,Davis JD,Rajadhyaksha M,Graham NMH,Pirozzi

更新日期：2020-02-01 00:00:00

abstract：IMPORTANCE:The differential diagnosis for oral lentigines includes several syndromes with important associated systemic findings. McCune-Albright syndrome (MAS), a mosaic condition associated with café au lait pigmentation, is not typically considered a mucosal lentiginosis syndrome. The clinical phenotype of MAS is va...

journal_title：JAMA dermatology

authors： Pichard DC,Boyce AM,Collins MT,Cowen EW

更新日期：2014-07-01 00:00:00

abstract：Importance:Staged excision of lentigo maligna (LM) often requires multiple stages and can result in significant cosmetic morbidity. Imiquimod cream has been used off-label as monotherapy in the treatment of LM and may be used in the neoadjuvant setting prior to staged excision as a strategy to reduce the size of the su...

journal_title：JAMA dermatology

authors： Donigan JM,Hyde MA,Goldgar DE,Hadley ML,Bowling M,Bowen GM

更新日期：2018-08-01 00:00:00

abstract：Importance:Psoriasis is associated with an increased risk of cardiovascular diseases. Subclinical atherosclerosis in patients with psoriasis has not been compared with other conditions associated with increased cardiovascular risk and more rigorous cardiovascular disease screening, such as type 2 diabetes. Objective:T...

journal_title：JAMA dermatology

authors： Mansouri B,Kivelevitch D,Natarajan B,Joshi AA,Ryan C,Benjegerdes K,Schussler JM,Rader DJ,Reilly MP,Menter A,Mehta NN

更新日期：2016-11-01 00:00:00

abstract：Importance:Exercise is recommended as an adjuvant treatment for venous leg ulceration (VLU) to improve calf muscle pump function. However, the association of exercise with VLU healing has not been properly aggregated, and the effectiveness of different exercise interventions has not been characterized. Objective:To su...

journal_title：JAMA dermatology

authors： Jull A,Slark J,Parsons J

更新日期：2018-11-01 00:00:00

abstract：Importance:A phase 2 trial comparing talimogene laherparepvec plus ipilimumab vs ipilimumab monotherapy in patients with advanced unresectable melanoma found no differential benefit in progression-free survival (PFS) but noted objective response rates (ORRs) of 38.8% (38 of 98 patients) vs 18.0% (18 of 100 patients), r...

journal_title：JAMA dermatology

authors： Almutairi AR,Alkhatib NS,Oh M,Curiel-Lewandrowski C,Babiker HM,Cranmer LD,McBride A,Abraham I

更新日期：2019-01-01 00:00:00

abstract：Importance:Despite the growing popularity of cosmetic procedures, the sociocultural and quality-of-life factors that motivate patients to undergo such procedures are not well understood. Objective:To estimate the relative importance of factors that motivate patients to seek minimally invasive cosmetic procedures. Des...

journal_title：JAMA dermatology

authors： Maisel A,Waldman A,Furlan K,Weil A,Sacotte K,Lazaroff JM,Lin K,Aranzazu D,Avram MM,Bell A,Cartee TV,Cazzaniga A,Chapas A,Crispin MK,Croix JA,DiGiorgio CM,Dover JS,Goldberg DJ,Goldman MP,Green JB,Griffin CL,Haimo

更新日期：2018-10-01 00:00:00

abstract：Importance:Although regression is commonly observed in cutaneous melanoma, it is uncertain whether it is associated with patient prognosis. Objective:To determine whether histologically confirmed regression was associated with better or worse survival in patients with primary cutaneous melanoma. Design, Setting, and ...

journal_title：JAMA dermatology

authors： El Sharouni MA,Aivazian K,Witkamp AJ,Sigurdsson V,van Gils CH,Scolyer RA,Thompson JF,van Diest PJ,Lo SN

更新日期：2020-12-23 00:00:00

abstract：IMPORTANCE:Ustekinumab is a human monoclonal antibody that binds to the shared p40 subunit of interleukin (IL) 12 and IL-23. It is approved in the United States for adults (>18 years) with moderate to severe plaque psoriasis who are candidates for phototherapy or systemic therapy. In 1 phase 2 trial of ustekinumab for ...

journal_title：JAMA dermatology

authors： Stamell EF,Kutner A,Viola K,Cohen SR

更新日期：2013-12-01 00:00:00

abstract：Importance:Incidence rates of skin cancer are increasing globally, and the correct classification of skin lesions (SLs) into benign and malignant tissue remains a continuous challenge. A collective intelligence approach to skin cancer detection may improve accuracy. Objective:To evaluate the performance of 2 well-know...

journal_title：JAMA dermatology

authors： Kurvers RH,Krause J,Argenziano G,Zalaudek I,Wolf M

更新日期：2015-12-01 00:00:00

abstract：Importance:Breslow thickness is a 1-dimensional surrogate prognostic feature for tumor size, yet tissue sections have 2 dimensions. Therefore, a 2-dimensional feature, calculated tumor area (CTA), was devised. Objective:To determine CTA precision and prognostic value. Design, Setting, and Participants:This retrospect...

journal_title：JAMA dermatology

authors： Saldanha G,Yarrow J,Elsheikh S,O'Riordan M,Uraiby H,Bamford M

更新日期：2019-06-26 00:00:00

abstract：Importance:Melanoma risk factors and incidence in renal transplant recipients can inform decision making for both patients and clinicians. Objective:To determine risk factors and characteristics of renal transplant recipients who develop melanoma. Design, Setting, and Participants:This cohort study of a large nationa...

journal_title：JAMA dermatology

authors： Ascha M,Ascha MS,Tanenbaum J,Bordeaux JS

更新日期：2017-11-01 00:00:00