Transparency and Dermatologic Device Approval by the US Food and Drug Administration.

abstract：Importance:Necrobiotic xanthogranuloma (NXG) is a non-Langerhans cell histiocytosis classically associated with paraproteinemia attributable to plasma-cell dyscrasias or lymphoproliferative disorders. Despite the morbidity of NXG, the literature is limited to case reports and small studies, and diagnostic criteria are ...

journal_title：JAMA dermatology

authors： Nelson CA,Zhong CS,Hashemi DA,Ashchyan HJ,Brown-Joel Z,Noe MH,Imadojemu S,Micheletti RG,Vleugels RA,Wanat KA,Rosenbach M,Mostaghimi A

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVE:To compare the prevalence and incidence of type 2 diabetes mellitus between patients with psoriasis and those without psoriasis. DATA SOURCES:MEDLINE, EMBASE, and Cochrane Database of Systematic Reviews between January 1, 1980, and January 1, 2012. STUDY SELECTION:Observational (cohort, case-control, and cr...

journal_title：JAMA dermatology

authors： Armstrong AW,Harskamp CT,Armstrong EJ

更新日期：2013-01-01 00:00:00

abstract：Importance:Baricitinib, an oral selective Janus kinase 1 and 2 inhibitor, effectively reduced disease severity in moderate to severe atopic dermatitis (AD) in 2 phase 3 monotherapy studies. Objective:To assess the efficacy and safety of 4 mg and 2 mg of baricitinib in combination with background topical corticosteroid...

journal_title：JAMA dermatology

authors： Reich K,Kabashima K,Peris K,Silverberg JI,Eichenfield LF,Bieber T,Kaszuba A,Kolodsick J,Yang FE,Gamalo M,Brinker DR,DeLozier AM,Janes JM,Nunes FP,Thyssen JP,Simpson EL

更新日期：2020-12-01 00:00:00

abstract：IMPORTANCE:Cryolipolysis is the noninvasive reduction of fat with localized cutaneous cooling. Since initial introduction, over 650,000 cryolipolysis treatment cycles have been performed worldwide. We present a previously unreported, rare adverse effect following cryolipolysis: paradoxical adipose hyperplasia. OBSERVA...

journal_title：JAMA dermatology

authors： Jalian HR,Avram MM,Garibyan L,Mihm MC,Anderson RR

更新日期：2014-03-01 00:00:00

abstract：IMPORTANCE:Although cutaneous warts are common lesions, full remission is not always achieved with conventional therapies. Laser modalities including carbon dioxide (CO2), erbium:yttrium-aluminum-garnet (Er:YAG), pulsed dye (PDL), and Nd:YAG have been investigated as alternative treatments for warts. OBJECTIVE:To revi...

journal_title：JAMA dermatology

authors： Nguyen J,Korta DZ,Chapman LW,Kelly KM

更新日期：2016-09-01 00:00:00

abstract：IMPORTANCE:Nevi are among the strongest risk factors for melanoma. However, little is known about the association of many total nevi (TN) or atypical nevi (AN) with tumor thickness. OBJECTIVES:To examine the association between age and the number of TN and AN and to explore whether there was a relationship between TN ...

journal_title：JAMA dermatology

authors： Geller AC,Mayer JE,Sober AJ,Miller DR,Argenziano G,Johnson TM,Swetter SM

更新日期：2016-04-01 00:00:00

abstract：IMPORTANCE:Describing the relationship between the availability of free prescription drug samples and dermatologists' prescribing patterns on a national scale can help inform policy guidelines on the use of free samples in a physician's office. OBJECTIVES:To investigate the relationships between free drug samples and ...

journal_title：JAMA dermatology

authors： Hurley MP,Stafford RS,Lane AT

更新日期：2014-05-01 00:00:00

abstract：IMPORTANCE:Topical corticosteroids are the current first-line therapy for vulvar lichen sclerosus (VLS). UV-A1 phototherapy may be a promising alternative treatment option, but controlled studies are lacking. OBJECTIVE:To compare the efficacy of high-potent topical corticosteroids with UV-A1 phototherapy in the treatm...

journal_title：JAMA dermatology

authors： Terras S,Gambichler T,Moritz RK,Stücker M,Kreuter A

更新日期：2014-06-01 00:00:00

abstract：IMPORTANCE:Basal cell carcinomas (BCCs) are diagnosed by clinical evaluation, which can include dermoscopic evaluation, biopsy, and histopathologic examination. Recent translation of multiphoton microscopy (MPM) to clinical practice raises the possibility of noninvasive, label-free in vivo imaging of BCCs that could re...

journal_title：JAMA dermatology

authors： Balu M,Zachary CB,Harris RM,Krasieva TB,König K,Tromberg BJ,Kelly KM

更新日期：2015-10-01 00:00:00

abstract：Importance:High-cost biologic therapies have transformed the management of immune-mediated inflammatory diseases. To optimize outcomes and reduce costs, dose adjustment informed by measurement of circulating drug levels has been shown to be effective in various settings. However, limited evidence exists for this approa...

journal_title：JAMA dermatology

authors： Tsakok T,Wilson N,Dand N,Loeff FC,Bloem K,Baudry D,Duckworth M,Pan S,Pushpa-Rajah A,Standing JF,de Vries A,Alsharqi A,Becher G,Murphy R,Wahie S,Wright A,Griffiths CEM,Reynolds NJ,Barker J,Warren RB,Burden AD,Ris

更新日期：2019-09-18 00:00:00

abstract：IMPORTANCE:Solid-organ transplant recipients (OTRs) are at an increased risk for skin cancer. Prior studies have demonstrated a reduced incidence of skin cancer in renal OTRs treated with sirolimus. However, little information exists on the use of sirolimus for the prevention of skin cancer in nonrenal OTRs or those al...

journal_title：JAMA dermatology

authors： Karia PS,Azzi JR,Heher EC,Hills VM,Schmults CD

更新日期：2016-05-01 00:00:00

abstract：IMPORTANCE:Recently, a group of melanocytic tumors with loss of BAP1 expression has been described. The lesions may occur sporadically or as part of a familial cancer syndrome. They have distinct histopathologic features characterized by a nevus like silhouette and cytologic composition of large epithelioid melanocytes...

journal_title：JAMA dermatology

authors： Busam KJ,Wanna M,Wiesner T

更新日期：2013-03-01 00:00:00

abstract：Importance:Cutaneous squamous cell carcinoma (cSCC) has metastatic potential, but the prognostic value of current staging systems in nonselected patients is uncertain. Objective:To assess the effect of risk factors for metastasis and to evaluate validity and usefulness of 4 staging systems for cSCC using population-ba...

journal_title：JAMA dermatology

authors： Roscher I,Falk RS,Vos L,Clausen OPF,Helsing P,Gjersvik P,Robsahm TE

更新日期：2018-04-01 00:00:00

abstract：Importance:There is limited information regarding the influence of patient demographics, tumor characteristics, and treatment type on the survival of patients with dermatofibrosarcoma protuberans (DFSP). Objective:To assess prognostic factors and to evaluate the influence of treatment modality on overall survival of p...

journal_title：JAMA dermatology

authors： Criscito MC,Martires KJ,Stein JA

更新日期：2016-12-01 00:00:00

abstract：Importance:Incidence rates of skin cancer are increasing globally, and the correct classification of skin lesions (SLs) into benign and malignant tissue remains a continuous challenge. A collective intelligence approach to skin cancer detection may improve accuracy. Objective:To evaluate the performance of 2 well-know...

journal_title：JAMA dermatology

authors： Kurvers RH,Krause J,Argenziano G,Zalaudek I,Wolf M

更新日期：2015-12-01 00:00:00

abstract：IMPORTANCE:Psoriasis and atopic dermatitis (AD) are inflammatory diseases thought to be mediated by helper T-cell subtypes 1 and 2 (TH1 and TH2), respectively. Although psoriasis and AD show histopathologic differences during chronic disease, they are difficult to distinguish histologically during erythrodermic exacerb...

journal_title：JAMA dermatology

authors： Moy AP,Murali M,Kroshinsky D,Duncan LM,Nazarian RM

更新日期：2015-07-01 00:00:00

abstract：Importance:Protective effects of UV-B radiation against nonmelanoma skin cancer (NMSC) are exerted via signaling mechanisms involving the vitamin D receptor (VDR). Recent studies have examined single-nucleotide polymorphisms (SNPs) in the VDR, resulting in contradictory findings as to whether these polymorphisms increa...

journal_title：JAMA dermatology

authors： Burns EM,Guroji P,Ahmad I,Nasr HM,Wang Y,Tamimi IA,Stiefel E,Abdelgawwad MS,Shaheen A,Muzaffar AF,Bush LM,Hurst CB,Griffin RL,Elmets CA,Yusuf N

更新日期：2017-10-01 00:00:00

abstract：IMPORTANCE:Recent data demonstrated somatic mutations in GJB2 that were present in affected porokeratotic eccrine ostial and dermal duct nevus (PEODDN) tissue but absent in unaffected skin. Recognizing that PEODDN lesions can also appear in individuals with keratitis-ichthyosis-deafness syndrome and finding somatic mut...

journal_title：JAMA dermatology

authors： Levinsohn JL,McNiff JM,Antaya RJ,Choate KA

更新日期：2015-06-01 00:00:00

abstract：IMPORTANCE:Omalizumab has emerged as a novel and effective treatment option for patients with antihistamine-resistant chronic urticaria. It is unclear whether patients with recurrent urticaria symptoms after discontinuation of omalizumab treatment can benefit from retreatment. OBJECTIVE:To assess the response of patie...

journal_title：JAMA dermatology

authors： Metz M,Ohanyan T,Church MK,Maurer M

更新日期：2014-03-01 00:00:00

abstract：IMPORTANCE:The efficacy of treatment for psoriasis must be balanced against potential adverse events. OBJECTIVE:To determine the effect of treatment on the risk of serious infections in patients with psoriasis. DESIGN, SETTING, AND PARTICIPANTS:A multicenter, longitudinal, disease-based registry (Psoriasis Longitudin...

journal_title：JAMA dermatology

authors： Kalb RE,Fiorentino DF,Lebwohl MG,Toole J,Poulin Y,Cohen AD,Goyal K,Fakharzadeh S,Calabro S,Chevrier M,Langholff W,You Y,Leonardi CL

更新日期：2015-09-01 00:00:00

abstract：Importance:Skin cancer, the most common cancer in the United States, is highly associated with outdoor and indoor tanning behaviors. Although indoor tanning has been suggested to be more common among sexual minority (self-reported as homosexual, gay, or bisexual) men compared with heterosexual men, whether rates of ski...

journal_title：JAMA dermatology

authors： Mansh M,Katz KA,Linos E,Chren MM,Arron S

更新日期：2015-12-01 00:00:00

abstract：Importance:Increased rates of autoimmune conditions have been reported in association with systemic lupus erythematosus (SLE). Little is known about coexisting autoimmune conditions in patients with cutaneous lupus erythematosus (CLE) without SLE. Objective:To determine the prevalence and risk factors of having coexis...

journal_title：JAMA dermatology

authors： Kunzler E,Hynan LS,Chong BF

更新日期：2018-06-01 00:00:00

abstract：Importance:How patients' mental health is associated with their satisfaction with physicians is rarely studied among adults with skin conditions. Objective:To examine the association between mental health comorbidities in patients with psoriasis and their satisfaction with physicians. Design, Setting, and Participant...

journal_title：JAMA dermatology

authors： Read C,Armstrong AW

更新日期：2020-07-01 00:00:00

abstract：IMPORTANCE:Ustekinumab is a human monoclonal antibody that binds to the shared p40 subunit of interleukin (IL) 12 and IL-23. It is approved in the United States for adults (>18 years) with moderate to severe plaque psoriasis who are candidates for phototherapy or systemic therapy. In 1 phase 2 trial of ustekinumab for ...

journal_title：JAMA dermatology

authors： Stamell EF,Kutner A,Viola K,Cohen SR

更新日期：2013-12-01 00:00:00

abstract：Importance:Pyoderma gangrenosum and necrotizing Sweet syndrome are diagnostically challenging variants of neutrophilic dermatosis that can clinically mimic the cutaneous and systemic features of necrotizing fasciitis. Improved characterization of these rare variants is needed, as improper diagnosis may lead to inapprop...

journal_title：JAMA dermatology

authors： Sanchez IM,Lowenstein S,Johnson KA,Babik J,Haag C,Keller JJ,Ortega-Loayza AG,Cohen J,McCalmont TH,Demer AM,Mansh MD,Hylwa SA,Liu J,Shinkai K

更新日期：2019-01-01 00:00:00

abstract：IMPORTANCE:Treatment outcomes depend on adherence to the prescribed regimen. Primary nonadherence refers to not obtaining and starting to take a prescribed medication. The frequency of primary nonadherence to acne treatment has not been well characterized. The complexity of multidrug acne regimens may add to this probl...

journal_title：JAMA dermatology

authors： Anderson KL,Dothard EH,Huang KE,Feldman SR

更新日期：2015-06-01 00:00:00

abstract：Importance:Chronic graft-vs-host-disease (cGVHD) after allogeneic stem cell transplantation (AHSCT) may resemble autoimmune diseases. Anti-MDA5 (melanoma differentiation-associated gene 5) dermatopulmonary syndrome is a subset of dermatomyositis defined by specific clinical features and detection of anti-MDA5-antibodie...

journal_title：JAMA dermatology

authors： Lepelletier C,Bengoufa D,Lyes Z,de Masson A,Chasset F,Jachiet M,Michonneau D,Robin M,Peffault de Latour R,Sicre de Fontbrune F,Tandjaoui-Lambiotte Y,Bensussan A,Rybojad M,Tazi A,Bagot M,Socié G,Bergeron A,Bouaziz JD

更新日期：2017-02-01 00:00:00

abstract：IMPORTANCE:Purse-string suture is a closure method that purportedly reduces the scar area compared with second intention healing. Randomized clinical trials comparing these 2 methods appear to be limited or absent. OBJECTIVE:To determine if purse-string suture improves cosmetic outcome, healing time, and scar to defec...

journal_title：JAMA dermatology

authors： Joo J,Custis T,Armstrong AW,King TH,Omlin K,Kappel ST,Eisen DB

更新日期：2015-03-01 00:00:00

abstract：Importance:Erythromelalgia is a clinical diagnosis based on intermittent warmth, erythema, and pain in the distal extremities. One problem facing physicians is how to objectively test for this disease. Given that other painful conditions of the distal extremities (ie, neuropathy related to human immunodeficiency virus,...

journal_title：JAMA dermatology

authors： Mantyh WG,Dyck PJB,Dyck PJ,Engelstad JK,Litchy WJ,Sandroni P,Davis MDP

更新日期：2017-02-01 00:00:00

abstract：IMPORTANCE:Hydroxychloroquine-induced pigmentation is not a rare adverse effect. Our data support the hypothesis that hydroxychloroquine-induced pigmentation is secondary to ecchymosis or bruising. OBJECTIVE:To describe the clinical features and outcome of hydroxychloroquine (HCQ)-induced pigmentation in patients with...

journal_title：JAMA dermatology

authors： Jallouli M,Francès C,Piette JC,Huong du LT,Moguelet P,Factor C,Zahr N,Miyara M,Saadoun D,Mathian A,Haroche J,De Gennes C,Leroux G,Chapelon C,Wechsler B,Cacoub P,Amoura Z,Costedoat-Chalumeau N,Plaquenil LUpus Systemic

更新日期：2013-08-01 00:00:00