Prevalence, Incidence, and Risk of Cancer in Patients With Psoriasis and Psoriatic Arthritis: A Systematic Review and Meta-analysis.

abstract：Importance:Persistent radiation-induced alopecia (pRIA) and its management have not been systematically described. Objective:To characterize pRIA in patients with primary central nervous system (CNS) tumors or head and neck sarcoma. Design, Setting, and Participants:A retrospective cohort study of patients from Janua...

journal_title：JAMA dermatology

authors： Phillips GS,Freret ME,Friedman DN,Trelles S,Kukoyi O,Freites-Martinez A,Unger RH,Disa JJ,Wexler LH,Tinkle CL,Mechalakos JG,Dusza SW,Beal K,Wolden SL,Lacouture ME

更新日期：2020-09-01 00:00:00

abstract：Importance:Systemic and inhaled corticosteroids negatively affect bone remodeling and cause osteoporosis and bone fracture when given continuously or in high doses. However, risk of osteoporosis and major osteoporotic fracture (MOF) after application of topical corticosteroids (TCSs) is largely unexplored. Objective:T...

journal_title：JAMA dermatology

authors： Egeberg A,Schwarz P,Harsløf T,Andersen YMF,Pottegård A,Hallas J,Thyssen JP

更新日期：2021-01-20 00:00:00

abstract：IMPORTANCE:The differential diagnosis for oral lentigines includes several syndromes with important associated systemic findings. McCune-Albright syndrome (MAS), a mosaic condition associated with café au lait pigmentation, is not typically considered a mucosal lentiginosis syndrome. The clinical phenotype of MAS is va...

journal_title：JAMA dermatology

authors： Pichard DC,Boyce AM,Collins MT,Cowen EW

更新日期：2014-07-01 00:00:00

abstract：IMPORTANCE:Acquired cutis laxa is a rare cutaneous manifestation of hematologic malignancy. We report a case of γ heavy chain deposition disease (HCDD) associated with acquired cutis laxa, renal involvement, and hypocomplementemia and propose a mechanism of elastic fiber degradation in the skin of this patient with HCD...

journal_title：JAMA dermatology

authors： O'Malley JT,D'Agati VD,Sherman WH,Grossman ME

更新日期：2014-11-01 00:00:00

abstract：Importance:Although regression is commonly observed in cutaneous melanoma, it is uncertain whether it is associated with patient prognosis. Objective:To determine whether histologically confirmed regression was associated with better or worse survival in patients with primary cutaneous melanoma. Design, Setting, and ...

journal_title：JAMA dermatology

authors： El Sharouni MA,Aivazian K,Witkamp AJ,Sigurdsson V,van Gils CH,Scolyer RA,Thompson JF,van Diest PJ,Lo SN

更新日期：2020-12-23 00:00:00

abstract：IMPORTANCE:The efficacy of treatment for psoriasis must be balanced against potential adverse events. OBJECTIVE:To determine the effect of treatment on the risk of serious infections in patients with psoriasis. DESIGN, SETTING, AND PARTICIPANTS:A multicenter, longitudinal, disease-based registry (Psoriasis Longitudin...

journal_title：JAMA dermatology

authors： Kalb RE,Fiorentino DF,Lebwohl MG,Toole J,Poulin Y,Cohen AD,Goyal K,Fakharzadeh S,Calabro S,Chevrier M,Langholff W,You Y,Leonardi CL

更新日期：2015-09-01 00:00:00

abstract：Importance:In the US, incidence of and mortality due to anal carcinoma are rising faster than for most other cancers. Identifying populations who have a higher risk of developing anal cancers is critical to target preventive interventions. Objective:To assess the risk of developing anal carcinoma in adults living with...

journal_title：JAMA dermatology

authors： Arnold JD,Byrne ME,Monroe AK,Abbott SE,District of Columbia Cohort Executive Committee.

更新日期：2021-01-13 00:00:00

abstract：Importance:Melanoma risk factors and incidence in renal transplant recipients can inform decision making for both patients and clinicians. Objective:To determine risk factors and characteristics of renal transplant recipients who develop melanoma. Design, Setting, and Participants:This cohort study of a large nationa...

journal_title：JAMA dermatology

authors： Ascha M,Ascha MS,Tanenbaum J,Bordeaux JS

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Immune reconstitution inflammatory syndrome (IRIS) is a phenomenon initially described in patients with human immunodeficiency virus. Upon initiation of combination antiretroviral therapy, recovery of cellular immunity triggers inflammation to a preexisting infection or antigen that causes paradoxical worsen...

journal_title：JAMA dermatology

authors： Scharschmidt TC,Amerson EH,Rosenberg OS,Jacobs RA,McCalmont TH,Shinkai K

更新日期：2013-01-01 00:00:00

abstract：Importance:There are limited data among young adults on sunscreen use during childhood and adulthood and on the association of sunscreen use with melanoma risk. Objective:To assess correlates of early-life sunscreen use and the association between sunscreen use and risk of cutaneous melanoma before age 40 years. Desi...

journal_title：JAMA dermatology

authors： Watts CG,Drummond M,Goumas C,Schmid H,Armstrong BK,Aitken JF,Jenkins MA,Giles GG,Hopper JL,Mann GJ,Cust AE

更新日期：2018-09-01 00:00:00

abstract：Importance:Pubic hair grooming is a common practice that can lead to injury and morbidity. Objective:To identify demographic and behavioral risk factors associated with pubic hair grooming-related injuries to characterize individuals with high risk of injury and develop recommendations for safe grooming practices. De...

journal_title：JAMA dermatology

authors： Truesdale MD,Osterberg EC,Gaither TW,Awad MA,Elmer-DeWitt MA,Sutcliffe S,Allen I,Breyer BN

更新日期：2017-11-01 00:00:00

abstract：Importance:High-cost biologic therapies have transformed the management of immune-mediated inflammatory diseases. To optimize outcomes and reduce costs, dose adjustment informed by measurement of circulating drug levels has been shown to be effective in various settings. However, limited evidence exists for this approa...

journal_title：JAMA dermatology

authors： Tsakok T,Wilson N,Dand N,Loeff FC,Bloem K,Baudry D,Duckworth M,Pan S,Pushpa-Rajah A,Standing JF,de Vries A,Alsharqi A,Becher G,Murphy R,Wahie S,Wright A,Griffiths CEM,Reynolds NJ,Barker J,Warren RB,Burden AD,Ris

更新日期：2019-09-18 00:00:00

abstract：Importance:Population-level disease metrics are critical to guide the distribution of resources and implementation of public health initiatives. Internet search data reflect population interest in health topics and may be an alternative metric of disease characteristics when traditional sources are lacking, such as in ...

journal_title：JAMA dermatology

authors： Wehner MR,Nead KT,Linos E

更新日期：2017-09-01 00:00:00

abstract：IMPORTANCE:While monotherapy with biologic agents is effective for many patients with psoriasis, some patients require combination therapy. Evidence-based recommendations on combination therapy provide guidance for treating appropriately selected patients with psoriasis. OBJECTIVE:To make evidence-based, best-practice...

journal_title：JAMA dermatology

authors： Armstrong AW,Bagel J,Van Voorhees AS,Robertson AD,Yamauchi PS

更新日期：2015-04-01 00:00:00

abstract：Importance:The risk for skin cancer has been well characterized in white organ transplant recipients (OTRs); however, most patients on the waiting list for organ transplant in the United States are nonwhite. Little is known about cutaneous disease and skin cancer risk in this OTR population. Objective:To compare the i...

journal_title：JAMA dermatology

authors： Chung CL,Nadhan KS,Shaver CM,Ogrich LM,Abdelmalek M,Cusack CA,Malat GE,Pritchett EN,Doyle A

更新日期：2017-06-01 00:00:00

abstract：IMPORTANCE:Ustekinumab is a human monoclonal antibody that binds to the shared p40 subunit of interleukin (IL) 12 and IL-23. It is approved in the United States for adults (>18 years) with moderate to severe plaque psoriasis who are candidates for phototherapy or systemic therapy. In 1 phase 2 trial of ustekinumab for ...

journal_title：JAMA dermatology

authors： Stamell EF,Kutner A,Viola K,Cohen SR

更新日期：2013-12-01 00:00:00

abstract：IMPORTANCE:Describing the relationship between the availability of free prescription drug samples and dermatologists' prescribing patterns on a national scale can help inform policy guidelines on the use of free samples in a physician's office. OBJECTIVES:To investigate the relationships between free drug samples and ...

journal_title：JAMA dermatology

authors： Hurley MP,Stafford RS,Lane AT

更新日期：2014-05-01 00:00:00

abstract：Importance:Drug-induced hypersensitivity syndrome (DIHS), also known as drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome, is a potentially life-threatening reaction to medications with a mortality rate up to 10%. Standard therapy involves the use of systemic corticosteroids with tapering doses ext...

journal_title：JAMA dermatology

authors： Kirchhof MG,Wong A,Dutz JP

更新日期：2016-11-01 00:00:00

abstract：Importance:Use of systemic therapies for moderate to severe psoriasis in children is increasing, but comparative data on their use and toxicities are limited. Objective:To assess patterns of use and relative risks of systemic agents for moderate to severe psoriasis in children. Design, Setting, and Participants:A ret...

journal_title：JAMA dermatology

authors： Bronckers IMGJ,Seyger MMB,West DP,Lara-Corrales I,Tollefson M,Tom WL,Hogeling M,Belazarian L,Zachariae C,Mahé E,Siegfried E,Philipp S,Szalai Z,Vleugels RA,Holland K,Murphy R,Baselga E,Cordoro K,Lambert J,Alexopoulos

更新日期：2017-11-01 00:00:00

abstract：IMPORTANCE:Telaprevir, combined with pegylated interferon alfa and ribavirin, is an efficacious approach to treat hepatitis C virus infection. A morbilliform eruption associated with telaprevir is a common adverse effect experienced by patients. Current guidelines mandate telaprevir discontinuation in any patient with ...

journal_title：JAMA dermatology

authors： Strazzula L,Pratt DS,Zardas J,Chung RT,Thiim M,Kroshinsky D

更新日期：2014-07-01 00:00:00

abstract：IMPORTANCE:How complications associated with chronic venous insufficiency (CVI) develop is not clear. The central source of the complications is likely a dysfunction of the calf muscle pump, which includes veins and their valves, the gastrocnemius and other lower leg and foot muscles as well as the nerves supplying the...

journal_title：JAMA dermatology

authors： Yim E,Vivas A,Maderal A,Kirsner RS

更新日期：2014-04-01 00:00:00

abstract：IMPORTANCE:Apart from the atypical mole phenotype, development of new melanocytic nevi in older individuals is uncommon and considered worrisome for melanoma. We performed a retrospective case series in a Veterans Affairs population from 1991 to 2013 to characterize blue nevi (BN) by patient age at biopsy, location, se...

journal_title：JAMA dermatology

authors： Cabral ES,Chen FW,Egbert BM,Swetter SM

更新日期：2014-08-01 00:00:00

abstract：IMPORTANCE:Recent data demonstrated somatic mutations in GJB2 that were present in affected porokeratotic eccrine ostial and dermal duct nevus (PEODDN) tissue but absent in unaffected skin. Recognizing that PEODDN lesions can also appear in individuals with keratitis-ichthyosis-deafness syndrome and finding somatic mut...

journal_title：JAMA dermatology

authors： Levinsohn JL,McNiff JM,Antaya RJ,Choate KA

更新日期：2015-06-01 00:00:00

abstract：Importance:Pyoderma gangrenosum and necrotizing Sweet syndrome are diagnostically challenging variants of neutrophilic dermatosis that can clinically mimic the cutaneous and systemic features of necrotizing fasciitis. Improved characterization of these rare variants is needed, as improper diagnosis may lead to inapprop...

journal_title：JAMA dermatology

authors： Sanchez IM,Lowenstein S,Johnson KA,Babik J,Haag C,Keller JJ,Ortega-Loayza AG,Cohen J,McCalmont TH,Demer AM,Mansh MD,Hylwa SA,Liu J,Shinkai K

更新日期：2019-01-01 00:00:00

abstract：IMPORTANCE:Purse-string suture is a closure method that purportedly reduces the scar area compared with second intention healing. Randomized clinical trials comparing these 2 methods appear to be limited or absent. OBJECTIVE:To determine if purse-string suture improves cosmetic outcome, healing time, and scar to defec...

journal_title：JAMA dermatology

authors： Joo J,Custis T,Armstrong AW,King TH,Omlin K,Kappel ST,Eisen DB

更新日期：2015-03-01 00:00:00

abstract：IMPORTANCE:Psoriasis and atopic dermatitis (AD) are inflammatory diseases thought to be mediated by helper T-cell subtypes 1 and 2 (TH1 and TH2), respectively. Although psoriasis and AD show histopathologic differences during chronic disease, they are difficult to distinguish histologically during erythrodermic exacerb...

journal_title：JAMA dermatology

authors： Moy AP,Murali M,Kroshinsky D,Duncan LM,Nazarian RM

更新日期：2015-07-01 00:00:00

abstract：IMPORTANCE:Topical corticosteroids are the current first-line therapy for vulvar lichen sclerosus (VLS). UV-A1 phototherapy may be a promising alternative treatment option, but controlled studies are lacking. OBJECTIVE:To compare the efficacy of high-potent topical corticosteroids with UV-A1 phototherapy in the treatm...

journal_title：JAMA dermatology

authors： Terras S,Gambichler T,Moritz RK,Stücker M,Kreuter A

更新日期：2014-06-01 00:00:00

abstract：Importance:There is limited information regarding the influence of patient demographics, tumor characteristics, and treatment type on the survival of patients with dermatofibrosarcoma protuberans (DFSP). Objective:To assess prognostic factors and to evaluate the influence of treatment modality on overall survival of p...

journal_title：JAMA dermatology

authors： Criscito MC,Martires KJ,Stein JA

更新日期：2016-12-01 00:00:00

abstract：Importance:Protective effects of UV-B radiation against nonmelanoma skin cancer (NMSC) are exerted via signaling mechanisms involving the vitamin D receptor (VDR). Recent studies have examined single-nucleotide polymorphisms (SNPs) in the VDR, resulting in contradictory findings as to whether these polymorphisms increa...

journal_title：JAMA dermatology

authors： Burns EM,Guroji P,Ahmad I,Nasr HM,Wang Y,Tamimi IA,Stiefel E,Abdelgawwad MS,Shaheen A,Muzaffar AF,Bush LM,Hurst CB,Griffin RL,Elmets CA,Yusuf N

更新日期：2017-10-01 00:00:00

abstract：IMPORTANCE:Atopic dermatitis (AD) is a common skin condition treated by dermatologists, allergists, pediatricians, and primary care physicians. Several treatment guidelines and therapeutic parameters exist for the management of this disease. Health care professionals may be unaware of guidelines created by specialty or...

journal_title：JAMA dermatology

authors： Mohan GC,Lio PA

更新日期：2015-09-01 00:00:00