Abstract:
:The radiation therapy carried out by means of heavy charged particles (such as carbon ions) and neutrons is rapidly becoming widespread worldwide. The success of these radiation therapies relies on the high density of energy released by these particles or by secondary particles produced after primary interaction with matter. The biological damages produced by ionising radiations in tissues and cells depend more properly on the energy released per unit pathlength, which is the linear energy transfer and which determines the radiation quality. To improve the therapy effectiveness, it is necessary to grasp the mechanisms of free radical production and distribution after irradiation with these particles when compared with the photon beams. In this work some preliminary results on the analysis of the spatial distributions of the free radicals produced after exposure of ammonium tartrate crystals to various radiation beams ((60)Co gamma photons and thermal neutrons) were reported. Electron spin resonance analyses were performed by the electron spin echo technique, which allows the determination of local spin concentrations and by double electron-electron resonance technique, which is able to measure the spatial distance distribution (range 1.5-8 nm) among pairs of radicals in solids. The results of these analyses are discussed on the basis of the different distributions of free radicals produced by the two different radiation beams used.
journal_name
Radiat Prot Dosimetryjournal_title
Radiation protection dosimetryauthors
Marrale M,Longo A,Barbon A,Brustolon M,Brai Mdoi
10.1093/rpd/ncu033subject
Has Abstractpub_date
2014-10-01 00:00:00pages
398-402issue
1-4eissn
0144-8420issn
1742-3406pii
ncu033journal_volume
161pub_type
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