Living donor lobar lung transplantation: a longstanding concept being revisited with the same old NEMESIS.

abstract：:The transmission of forces from the respiratory muscles to the lung across the extremely thin pleural space has been poorly understood because of the difficulty of accurately measuring pleural liquid and pleural surface pressure (lung static recoil or transpulmonary pressure). Recent results using relatively noninvasi...

journal_title：Lung

authors： Lai-Fook SJ

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Several clinical trials of chemotherapy for non-small-cell lung cancer (NSCLC) have been conducted to date. However, these studies have not been effective at identifying category 1 recommended strategies for systemic chemotherapy according to the National Comprehensive Cancer Network clinical practice guidel...

journal_title：Lung

authors： Inoue K,Narukawa M,Takeuchi M

更新日期：2012-08-01 00:00:00

abstract：:Exhaled breath condensate analysis is a developing method for investigating airway pathology. Impact of food and drink on breath condensate composition has not been systematically addressed. The aim of the study was to follow exhaled breath condensate pH after drinking an acidic and a neutral beverage. Breath condensa...

journal_title：Lung

authors： Kullmann T,Barta I,Antus B,Horváth I

更新日期：2008-07-01 00:00:00

abstract：:This study was designed to use volumetric capnography to evaluate the breathing pattern and ventilation inhomogeneities in patients with chronic sputum production and bronchiectasis and to correlate the phase 3 slope of the capnographic curve to spirometric measurements. Twenty-four patients with cystic fibrosis (CF) ...

journal_title：Lung

authors： Veronez L,Moreira MM,Soares ST,Pereira MC,Ribeiro MA,Ribeiro JD,Terzi RG,Martins LC,Paschoal IA

更新日期：2010-06-01 00:00:00

abstract：:Overlap syndrome and represents a complex clinical condition in pulmonary medicine. We discuss in this letter factors related with mortality after long-term effects CPAP and key differences between hypercapnic versus hypoxemic overlap patients. ...

journal_title：Lung

authors： Esquinas AM,Marrero FL,Esteva JN

更新日期：2014-10-01 00:00:00

abstract：:We aimed to evaluate the utility of coagulation markers for the prediction of rapidly progressive interstitial lung disease (RP-ILD) in patients with dermatomyositis (DM). In this retrospective study, 29 patients with DM-associated ILD were analyzed. The number of patients with RP-ILD was 15 (52%). The baseline clinic...

journal_title：Lung

authors： Sagawa T,Kida T,Inaba T,Yokota I,Sagawa R,Kasahara A,Kaneshita S,Inoue T,Nagahara H,Fujioka K,Wada M,Kohno M,Kawahito Y

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Exhaled nitric oxide (NO) levels have been reported to be lower in patients with cystic fibrosis (CF) than in controls; however the mechanism(s) responsible and the effect on pathogenesis are unclear. The objective of these studies was to determine if the low levels of gas phase NO (gNO) could be reproduced ...

journal_title：Lung

authors： Ostrowski LE,Stewart D,Hazucha M

更新日期：2012-10-01 00:00:00

abstract：:In severe asthma attacks beta 2-sympathomimetics lose part of their therapeutic efficiency. To elucidate this loss of efficiency in an experimental model we compared the relaxant potency of salbutamol (SAL), fenoterol (FEN), formoterol (FOR), and (-)-isoprenaline (ISO) in guinea pig tracheae partially and maximally pr...

journal_title：Lung

authors： Lemoine H,Overlack C,Köhl A,Worth H,Reinhardt D

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to evaluate the clinical and radiological features of patients with fungal infection mimicking thoracic malignancy and to establish a diagnostic approach for both clinicians and radiologists to avoid misdiagnosis. METHODS:In this retrospective study, we reviewed clinical and com...

journal_title：Lung

authors： Guimarães MD,Marchiori E,Meirelles GS,Hochhegger B,Santana PR,Gross JL,Bitencourt AG,Boonsirikamchai P,Godoy MC

更新日期：2013-12-01 00:00:00

abstract：:Clusterin is an enigmatic glycoprotein with a nearly ubiquitous tissue distribution. It plays important roles in various pathophysiological processes, including tissue remodeling, reproduction, lipid transport, complement regulation, and apoptosis. Clusterin appears to have two main isoforms that result from alternati...

journal_title：Lung

authors： Li H,Liu S,Zhu X,Yang S,Xiang J,Chen H

更新日期：2010-10-01 00:00:00

abstract：:Immune cell airway infiltration and the bronchovascular remodeling process have shown to be promising in the understanding of bronchiolitis obliterans (BO) pathogenesis. In this study we sought to validate the importance of immune cells, whether diffusely distributed or forming lymphoid follicles, collagen density, an...

journal_title：Lung

authors： Garippo AL,Parra ER,Teodoro WR,Veloza AP,Yoshinari NH,Capelozzi VL

更新日期：2006-07-01 00:00:00

abstract：:Genomic alterations in lung cancer tissues have been observed in various studies. To analyze the aberrations in the genome of lung cancer patients, we used array comparative genomic hybridization (array CGH) in 15 lung adenocarcinoma (AdC) tissues. Copy number gains and losses in chromosomal regions were detected and ...

journal_title：Lung

authors： Choi JS,Zheng LT,Ha E,Lim YJ,Kim YH,Wang YP,Lim Y

更新日期：2006-11-01 00:00:00

abstract：:The aim of this study was to test the hypothesis that systemic inflammation in patients with chronic obstructive pulmonary disease (COPD) is accompanied by enhanced interleukin 18 (IL-18) expression in skeletal muscle, which may precede muscle weight loss. Twenty patients with moderate to severe COPD [12 women, 66 +/-...

journal_title：Lung

authors： Petersen AM,Penkowa M,Iversen M,Frydelund-Larsen L,Andersen JL,Mortensen J,Lange P,Pedersen BK

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Pulmonary hypertension (PH) is a comorbidity associated with increased mortality in chronic obstructive pulmonary disease (COPD) patients. It is not known which clinical markers are predictive of PH in COPD. The goal of this study was to develop a clinical tool to identify patients who should be sent for ini...

journal_title：Lung

authors： Gartman EJ,Blundin M,Klinger JR,Yammine J,Roberts MB,Dennis McCool F

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Mannitol is a novel osmotic indirect bronchial challenge agent used to aid asthma diagnosis and management and is thought to reflect underlying inflammatory processes in asthma. Our objective was to evaluate relationships between mannitol airway hyperresponsiveness (AHR) and other measures of airway inflamma...

journal_title：Lung

authors： Anderson WJ,Lipworth BJ

更新日期：2012-10-01 00:00:00

abstract：RATIONALE:The clinical characteristics and prognostic impact of radiographic patterns of patients with nontuberculous mycobacterial lung disease (NTM-LD) are rarely evaluated. DESIGN:Patients with NTM-LD from 2007 to 2009 in a single medical center in Taiwan were identified. Their radiographic patterns were reviewed a...

journal_title：Lung

authors： Shu CC,Lee CH,Hsu CL,Wang JT,Wang JY,Yu CJ,Lee LN,TAMI Group.

更新日期：2011-12-01 00:00:00

abstract：:Recent research showed group B patients express higher mortality compared to group C patients when GOLD A-D grouping is used. We aimed to compare the prognostic accuracy of three GOLD classification systems, I-IV ("pre-2011"), A-D ("2011-2016") and A-D ("2017-present") in relation to mortality, exacerbation risk, qual...

journal_title：Lung

authors： Plutinsky M,Brat K,Svoboda M,Zatloukal J,Popelkova P,Koblizek V

更新日期：2019-04-01 00:00:00

abstract：:Impaired phagocytosis of Pseudomonas aeruginosa was found in isolated monocytes of peripheral blood of cystic fibrosis patients, but not in their neutrophils, as reported some years ago. In the present study, we analysed the phagocytic capacity of peripheral blood neutrophils and monocytes of cystic fibrosis patients ...

journal_title：Lung

authors： Leuer L,Krill A,Wilkens H,Wagenpfeil G,Bischoff M,Meier C,Bals R,Tschernig T

更新日期：2020-02-01 00:00:00

abstract：:Eosinophils have been shown to play a role in allergen-induced airway responses. The aim in this study was to examine the effects of TAK-661, a newly developed product as a specific inhibitory agent of eosinophil chemotaxis, on antigen-induced asthmatic responses in allergic sheep model. Seven Ascaris-sensitive, "dual...

journal_title：Lung

authors： Fujimoto K,Tsunoda T,Koizumi T,Kubo K

更新日期：2002-01-01 00:00:00

abstract：:Methacholine challenge testing (MCT) is widely used to assess airway hyperresponsiveness (AHR). Traditionally, a 20% or greater decline in forced expiratory volume in 1 (FEV(1)) is the primary outcome measure. We examined whether the inclusion of wheeze detection as outcome measure influenced the categorical interpret...

journal_title：Lung

authors： Bohadana AB,Michaely JP

更新日期：2006-05-01 00:00:00

abstract：PURPOSE:Sarcoidosis is a chronic granulomatous inflammatory disease of unknown etiology with heterogeneous outcomes. This study reviewed the clinical outcome status (COS) and organ involvement of Israeli sarcoidosis patients during a five-year period. Further, we compared our results to the 'World Association of Sarcoi...

journal_title：Lung

authors： Markevitz N,Epstein Shochet G,Levi Y,Israeli-Shani L,Shitrit D

更新日期：2017-08-01 00:00:00

abstract：:Accessory cardiac bronchus is a poorly recognized, usually asymptomatic, congenital abnormality of the bronchial tree. Recognition of bronchial anomalies is important since they are associated with clinical complications including recurrent episodes of infection, hemoptysis, and in some cases malignancy. ...

journal_title：Lung

authors： Barreiro TJ,Gemmel D

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Pulmonary arterial hypertension (PAH) is a deadly disease, and the molecular mechanism of PAH has not been clarified clearly. The objective of this study was to identify possible biomarkers and explore the potential mechanisms of Schistosoma-induced PAH. METHODS:GSE49114 RNA-Seq data developed from mouse wh...

journal_title：Lung

authors： Sun Y,Lin X,Li L

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Patients with various chronic respiratory diseases have a higher incidence of gastroesophageal reflux disease (GERD)-related symptoms, but the mechanisms of the relationship between GERD symptoms and chronic obstructive pulmonary disease (COPD) remain unclear. The aim of the present study was to explore the ...

journal_title：Lung

authors： Liang BM,Feng YL

更新日期：2012-06-01 00:00:00

abstract：:Benralizumab and mepolizumab are new therapies for severe eosinophilic asthma. They are both humanized IgG antibodies, targeting the IL-5 receptor and IL-5, respectively, suppressing the corresponding pathways. No specific biomarkers have been proposed to evaluate treatment response to benralizumab or mepolizumab. The...

journal_title：Lung

authors： Vantaggiato L,Perruzza M,Refini RM,Bergantini L,d'Alessandro M,Cameli P,Perruzza D,Bini L,Bargagli E,Landi C

更新日期：2020-10-01 00:00:00

abstract：:The effect of beta 2-adrenoceptor agonists on airway smooth muscle relaxation may be subject to desensitization. It could be modified by glucocorticosteroid treatment. An increase in the beta 2 agonist response by glucocorticosteroids in vitro has been described. We studied the effects of acute and chronic treatment w...

journal_title：Lung

authors： Seco AJ,Salgueiro ME,Manso G

更新日期：1995-01-01 00:00:00

abstract：:A large-scale outbreak of life-threatening, inhaled synthetic cannabinoids (Spice/K2)-associated coagulopathy with bleeding complications was recently reported in Illinois. The causative agents were brodifacoum, difenacoum, and bromadiolone, potent, long-acting, 4-hydroxycoumarin anticoagulant rodenticides (LAAR) that...

journal_title：Lung

authors： Tole M,LaBedz S,Feinstein DL,Rubinstein I

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Survival implications of pre-transplant antibodies to human leukocyte antigens prior to lung transplantation (LTx) in adult cystic fibrosis (CF) patients are unknown. METHODS:Data from the United Network for Organ Sharing Registry (1987-2013) were used to compare survival differences in adult CF patients wi...

journal_title：Lung

authors： Hayes D Jr,Tumin D,Tobias JD

更新日期：2016-06-01 00:00:00

abstract：INTRODUCTION:Lung cancer is the leading cause of cancer death in the USA, claiming more than 140,000 deaths annually. Delays in diagnosis and treatment can lead to missed opportunities for both curative and life prolonging therapies. This study aimed to evaluate duration of time to diagnosis and first treatment, as wel...

journal_title：Lung

authors： Albano D,Bilfinger T,Feraca M,Kuperberg S,Nemesure B

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Asbestos is a carcinogen linked to malignant mesothelioma (MM) and lung cancer. Some gene aberrations related to asbestos exposure are recognized, but many associated mutations remain obscure. We performed exome sequencing to determine the association of previously known mutations (driver gene mutations) wit...

journal_title：Lung

authors： Mäki-Nevala S,Sarhadi VK,Knuuttila A,Scheinin I,Ellonen P,Lagström S,Rönty M,Kettunen E,Husgafvel-Pursiainen K,Wolff H,Knuutila S

更新日期：2016-02-01 00:00:00