Efficacy and safety of muscarinic antagonists as add-on therapy for male lower urinary tract symptoms.

abstract：:Actinobacillus pleuropneumoniae (App) is the causative agent of porcine pleuropneumonia. Although App produces several virulence factors, Apx toxins, the primary App virulence factors, have been the focus of numerous studies. However, the host response against the Apx toxins has not been elucidated at the transcriptom...

journal_title：Scientific reports

authors： Kim S,Oh MW,Bin Park W,Yoo HS

更新日期：2019-03-27 00:00:00

abstract：:To evaluate the association between vision-related quality of life (QoL), physical inactivity, and locomotor dysfunction in subjects with visual impairment.This cross-sectional study included 215 visually impaired subjects recruited from six ophthalmology departments in Japan. The physical inactivity and locomotor dys...

journal_title：Scientific reports

authors： Inoue S,Kawashima M,Hiratsuka Y,Nakano T,Tamura H,Ono K,Murakami A,Tsubota K,Yamada M

更新日期：2018-08-13 00:00:00

abstract：:Cardiac arrhythmias are often associated with mutations in ion channels or other proteins. To enable drug development for distinct arrhythmias, model systems are required that allow implementing patient-specific mutations. We assessed a muscular pump in Caenorhabditis elegans. The pharynx utilizes homologues of most o...

journal_title：Scientific reports

authors： Schüler C,Fischer E,Shaltiel L,Steuer Costa W,Gottschalk A

更新日期：2015-09-24 00:00:00

abstract：:Oceanic submesoscale currents (SMCs) occur on an scale of 0.1-10 km horizontally and have a large influence on the oceanic variability and on ecosystems. At the mesoscale (10-250 km), oceanic thermal and current feedbacks are known to have a significant influence on the atmosphere and on oceanic dynamics. However, air...

journal_title：Scientific reports

authors： Renault L,McWilliams JC,Gula J

更新日期：2018-09-06 00:00:00

abstract：:We developed a spongy-like porous polymer (spongy monolith) consisting of poly(ethylene-co-glycidyl methacrylate) with continuous macropores that allowed efficient in situ reaction between the epoxy groups and proteins of interest. Immobilization of protein A on the spongy monolith enabled high-yield collection of imm...

journal_title：Scientific reports

authors： Kubota K,Kubo T,Tanigawa T,Naito T,Otsuka K

更新日期：2017-03-14 00:00:00

abstract：:In this study, nanowires/nanowalls were generated on a silicon wafer through a chemical etching method. Octadecyltrichlorosilane (OTS) was deposited onto the nanowire/nanowall surfaces to alter their hydrophobicity. The hydrophobic characteristics of the surfaces were further modified via a 1.5-μm-thick layer of n-oct...

journal_title：Scientific reports

authors： Yilbas BS,Salhi B,Yousaf MR,Al-Sulaiman F,Ali H,Al-Aqeeli N

更新日期：2016-12-09 00:00:00

abstract：:Diabetes mellitus (DM) significantly increases myocardial ischemia/reperfusion (MI/R) injury. During DM, cardioprotection induced by conventional pre-conditioning (PreCon) is decreased due to impaired AMP-activated protein kinase (AMPK) signaling. The current study investigated whether PreCon with inhaled anesthetic s...

journal_title：Scientific reports

authors： Xie D,Zhao J,Guo R,Jiao L,Zhang Y,Lau WB,Lopez B,Christopher T,Gao E,Cao J,Ma X,Wang Y

更新日期：2020-01-08 00:00:00

abstract：:Silicene is an exciting two-dimensional material that shares many of graphene's electronic properties, but differs in its structural buckling. This buckling allows opening a bandgap in silicene through the application of a perpendicular electric field. Here we show that this buckling also enables highly effective modu...

journal_title：Scientific reports

authors： Al-Dirini F,Hossain FM,Mohammed MA,Nirmalathas A,Skafidas E

更新日期：2015-10-06 00:00:00

abstract：:Grapevine (Vitis vinifera L.) is one of the classical fruits of the Old World. Among the thousands of domesticated grapevine varieties and variable wild sylvestris populations, the range of variation in pip morphology is very wide. In this study we scanned representative samples of grape pip populations, in an attempt...

journal_title：Scientific reports

authors： Karasik A,Rahimi O,David M,Weiss E,Drori E

更新日期：2018-04-25 00:00:00

abstract：:Bacillus widely exists in wet natural environment such as soil, water and air, and is often studied as one of representative microorganisms for microbiologically influenced corrosion(MIC) research. In this paper, the growth curve of Bacillus subtilis isolated from marine environment was determined by turbidimetry and ...

journal_title：Scientific reports

authors： Wang YS,Liu L,Fu Q,Sun J,An ZY,Ding R,Li Y,Zhao XD

更新日期：2020-04-01 00:00:00

abstract：:Next Generation Sequencing is dramatically increasing the number of known protein sequences, with related experimentally determined protein structures lagging behind. Structural bioinformatics is attempting to close this gap by developing approaches that predict structure-level characteristics for uncharacterized prot...

journal_title：Scientific reports

authors： Orlando G,Raimondi D,Vranken WF

更新日期：2016-11-18 00:00:00

abstract：:Limited reference values exist for visceral adipose tissue (VAT) mass measured by DXA. The objectives of this study were to provide reference values for DXA-derived VAT mass and compare the association with anthropometry measures. The study cohort comprised 677 men and 738 women aged 18-65 years from Western Australia...

journal_title：Scientific reports

authors： Staynor JMD,Smith MK,Donnelly CJ,Sallam AE,Ackland TR

更新日期：2020-10-30 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Alhabbab R,Blair P,Elgueta R,Stolarczyk E,Marks E,Becker PD,Ratnasothy K,Smyth L,Safinia N,Sharif-Paghaleh E,O'Connell S,Noelle RJ,Lord GM,Howard JK,Spencer J,Lechler RI,Lombardi G

更新日期：2020-04-06 00:00:00

abstract：:One of the health hazards of PM2.5 exposure is to induce pulmonary inflammatory responses. In our previous study, we demonstrated that exposing both the immortalized and primary human bronchial epithelial cells to PM2.5 results in a significant upregulation of VEGF production, a typical signaling event to trigger chro...

journal_title：Scientific reports

authors： Xu H,Xu X,Wang H,Qimuge A,Liu S,Chen Y,Zhang C,Hu M,Song L

更新日期：2019-11-12 00:00:00

abstract：:Exchange bias (EB) of magnetic nanoparticles (MNPs) in the nanoscale regime has been extensively studied by researchers, which have opened up a novel approach in tuning the magnetic anisotropy properties of magnetic nanoparticles (MNPs) in prospective application of biomedical research such as magnetic hyperthermia. I...

journal_title：Scientific reports

authors： Tsopoe SP,Borgohain C,Fopase R,Pandey LM,Borah JP

更新日期：2020-10-29 00:00:00

abstract：:Spiral waves anchored to obstacles in cardiac tissues may cause lethal arrhythmia. To unpin these anchored spirals, comparing to high-voltage side-effect traditional therapies, wave emission from heterogeneities (WEH) induced by the uniform electric field (UEF) has provided a low-voltage alternative. Here we provide a...

journal_title：Scientific reports

authors： Feng X,Gao X,Pan DB,Li BW,Zhang H

更新日期：2014-04-29 00:00:00

abstract：:Environmental contamination of arsenic (As) and its accumulation in rice (Oryza sativa L.) is of serious human health concern. In planta speciation of As is an important tool to understand As metabolism in plants. In the present study, we investigated root to shoot As translocation and speciation in rice exposed to in...

journal_title：Scientific reports

authors： Mishra S,Mattusch J,Wennrich R

更新日期：2017-01-17 00:00:00

abstract：:Dissimilatory nitrate reduction to ammonium (DNRA) is an important nitrate reduction process in estuarine sediments. This study reports the first investigation of DNRA in the Yellow River Estuary located in Eastern Shandong, China. Saltwater intrusion could affect the physicochemical characteristics and change the mic...

journal_title：Scientific reports

authors： Bu C,Wang Y,Ge C,Ahmad HA,Gao B,Ni SQ

更新日期：2017-07-28 00:00:00

abstract：:Hepatitis B is one of most etiologies of Liver cirrhosis in China, and clinically lacks the effective strategy for Hepatitis B caused cirrhosis (HBC) therapy. As a complementary and alternative medicine, Chinese Traditional Medicine (TCM) has special therapeutic effects for HBC. Here, we focus on the evolution process...

journal_title：Scientific reports

authors： Liu Y,Wang M,Luo Y,Chen J,Lu Y,Shi Y,Tang C,Zhou Q,Zhang H,Hu Y,Su S,Chen Q

更新日期：2017-09-08 00:00:00

abstract：:Rolling circle amplification (RCA) for generation of distinct fluorescent signals in situ relies upon the self-collapsing properties of single-stranded DNA in commonly used RCA-based methods. By introducing a cross-hybridizing DNA oligonucleotide during rolling circle amplification, we demonstrate that the fluorophore...

journal_title：Scientific reports

authors： Clausson CM,Arngården L,Ishaq O,Klaesson A,Kühnemund M,Grannas K,Koos B,Qian X,Ranefall P,Krzywkowski T,Brismar H,Nilsson M,Wählby C,Söderberg O

更新日期：2015-07-23 00:00:00

abstract：:The triboelectric nanogenerator (TENG) is a promising device in energy harvesting and self-powered sensing. In this work, we demonstrate a magnetic-assisted TENG, utilizing the magnetic force for electric generation. Maximum power density of 541.1 mW/m(2) is obtained at 16.67 MΩ for the triboelectric part, while the e...

journal_title：Scientific reports

authors： Han M,Zhang XS,Sun X,Meng B,Liu W,Zhang H

更新日期：2014-04-28 00:00:00

abstract：:BST-2/tetherin is an interferon-inducible antiviral protein that blocks the release of various enveloped viruses, including HIV-1. Hepatitis B virus (HBV), a major cause of liver disease, belongs to the Hepadnaviridae family of enveloped DNA viruses. Whether BST-2 regulates HBV production is largely unknown. In this r...

journal_title：Scientific reports

authors： Lv M,Zhang B,Shi Y,Han Z,Zhang Y,Zhou Y,Zhang W,Niu J,Yu XF

更新日期：2015-06-29 00:00:00

abstract：:Systemic Sclerosis (SSc) is a disease with limited therapeutic possibilities. Mesenchymal stem cells (MSCs)-therapy could be a promising therapeutic option, however the ideal MSCs source has not yet been found. To address this problem, we perform comparison between bone marrow (BM)-MSCs and adipose (A)-MSCs, by the mi...

journal_title：Scientific reports

authors： Di Benedetto P,Panzera N,Cipriani P,Mastroiaco V,Tessitore A,Liakouli V,Ruscitti P,Berardicurti O,Carubbi F,Guggino G,Bianchi A,Di Marco A,Ciccia F,Alesse E,Giacomelli R

更新日期：2019-05-09 00:00:00

abstract：:Applying a circular economy approach, this research explores the use of cheese whey permeate (CWP), by-product of whey ultrafiltration, as cheap substrate for the production of bacterial cellulose (BC) and Sakacin-A, to be used in an antimicrobial packaging material. BC from the acetic acid bacterium Komagataeibacter ...

journal_title：Scientific reports

authors： Rollini M,Musatti A,Cavicchioli D,Bussini D,Farris S,Rovera C,Romano D,De Benedetti S,Barbiroli A

更新日期：2020-12-07 00:00:00

abstract：:The aim of this study was to assess the liver stiffness values in children with obesity versus healthy children on 2D-SWE and TE taking into account different laboratory parameters. We performed a case-control study on 287 children aged between 3 to 18 years, admitted in a Romanian Pediatric Tertiary Hospital, which w...

journal_title：Scientific reports

authors： Mărginean CO,Meliţ LE,Ghiga DV,Săsăran MO

更新日期：2019-12-24 00:00:00

abstract：:Soil respiration (Rs) has been usually measured during daylight hours using manual chambers. This approach assumes that measurements made during a typical time interval (e.g., 9 to 11 am) represent the mean daily value; locally, this may not always be correct and could result in systematic bias of daily and annual Rs ...

journal_title：Scientific reports

authors： Cueva A,Bullock SH,López-Reyes E,Vargas R

更新日期：2017-09-20 00:00:00

abstract：:The rise of antibiotic resistance (AMR) is one of the most important public health threats worldwide.Today, increasing attention is being paid to multidrug resistant staphylococci isolated from healthcare and non-healthcare environments as the treatment of these bacteria has become increasingly difficult. In this stud...

journal_title：Scientific reports

authors： Cave R,Misra R,Chen J,Wang S,Mkrtchyan HV

更新日期：2019-08-01 00:00:00

abstract：:Since 2013, the outbreak or sporadic infection of a new reassortant H7N9 influenza virus in China has resulted in hundreds of deaths and thousands of illnesses. An H7N9 vaccine is urgently needed, as a licensed human vaccine against H7N9 influenza is currently not available. Here, we developed a recombinant adenovirus...

journal_title：Scientific reports

authors： Wang X,Fu W,Yuan S,Yang X,Song Y,Liu L,Chi Y,Cheng T,Xing M,Zhang Y,Zhang C,Yang Y,Zhu C,Zhang X,Xiong S,Xu J,Zhou D

更新日期：2017-05-12 00:00:00

abstract：:Colorectal cancer (CRC) is one of the most prevalent cancers worldwide and Alpha B-crystallin (CRYAB) protein has been identified as a prognostic biomarker for CRC. We evaluated CRYAB C-802G (rs14133)polymorphism in association with CRC risk and survival in Chinese population. We genotyped for CRYAB C-802G (rs14133), ...

journal_title：Scientific reports

authors： Wu X,Zheng YZ,Han B,Wang K

更新日期：2018-08-06 00:00:00

abstract：:The G-protein bile acid receptor 1 (GPBAR1) has emerged in the last decade as prominent target for the treatment of metabolic and inflammatory diseases including type 2 diabetes, obesity, and non-alcoholic steatohepatitis. To date numerous bile acid derivatives have been identified as GPBAR1 agonists, however their cl...

journal_title：Scientific reports

authors： Di Leva FS,Festa C,Carino A,De Marino S,Marchianò S,Di Marino D,Finamore C,Monti MC,Zampella A,Fiorucci S,Limongelli V

更新日期：2019-02-21 00:00:00