Abstract：
:Spiral waves anchored to obstacles in cardiac tissues may cause lethal arrhythmia. To unpin these anchored spirals, comparing to high-voltage side-effect traditional therapies, wave emission from heterogeneities (WEH) induced by the uniform electric field (UEF) has provided a low-voltage alternative. Here we provide a new approach using WEH induced by the circularly polarized electric field (CPEF), which has higher success rate and larger application scope than UEF, even with a lower voltage. And we also study the distribution of the membrane potential near an obstacle induced by CPEF to analyze its mechanism of unpinning. We hope this promising approach may provide a better alternative to terminate arrhythmia.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Feng X,Gao X,Pan DB,Li BW,Zhang Hdoi
10.1038/srep04831subject
Has Abstractpub_date
2014-04-29 00:00:00pages
4831issn
2045-2322pii
srep04831journal_volume
4pub_type
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