Abstract：
:Tomography--cross-sectional imaging based on measuring radiation transmitted through an object along different directions--enables non-invasive imaging of hidden stationary objects, such as internal bodily organs, from their sequentially measured projections. Here we adapt tomographic methods to visualize--in one laser shot--the instantaneous structure and evolution of a laser-induced object propagating through a transparent Kerr medium. We reconstruct 'movies' of a laser pulse's diffraction, self-focusing and filamentation from phase 'streaks' imprinted onto probe pulses that cross the main pulse's path simultaneously at different angles. Multiple probes are generated and detected compactly and simply, making the system robust, easy to align and adaptable to many problems. Our technique could potentially visualize, for example, plasma wakefield accelerators, optical rogue waves or fast ignitor pulses, light-velocity objects, whose detailed space-time dynamics are known only through intensive computer simulations.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Li Z,Zgadzaj R,Wang X,Chang YY,Downer MCdoi
10.1038/ncomms4085subject
Has Abstractpub_date
2014-01-01 00:00:00pages
3085issn
2041-1723pii
ncomms4085journal_volume
5pub_type
杂志文章abstract：:ARID1A, a component of the SWI/SNF chromatin remodeling complex, is a tumor suppressor with a high frequency of inactivating mutations in many cancers. Therefore, ARID1A deficiency has been exploited therapeutically for treating cancer. Here we show that ARID1A has a synthetic lethal interaction with aurora kinase A (...
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更新日期：2017-03-31 00:00:00
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更新日期：2016-08-17 00:00:00
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更新日期：2017-10-18 00:00:00
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