[The fibroid as clinical problem].

Abstract:

:Uterine fibroids are the most common benign tumours that affect women of reproductive age and they represent the main indication for surgery for benign uterine pathology. In 25% of cases, they become clinically apparent, causing heavy menstrual bleeding, pelvic pain and/or infertility. Therefore, fibroids have a notable impact on the economic costs for the health system and also on the quality of life of the women they afflict. Although MRI is the most precise technique to diagnose fibroids, ultrasound remains the most cost-effective method. Surgery has been the treatment of choice for years, and several minimally invasive procedures have recently been developed. There are a wide variety of conservative medical treatment options, which are continually expanding. Research on the biology of these tumours can lead to new therapeutic options for the management of fibroids as we better understand the role that growth factors and genetic mutations play in them.

journal_name

Med Clin (Barc)

journal_title

Medicina clinica

authors

Calaf J,Arqué M,Porta O,D'Angelo E

doi

10.1016/S0025-7753(13)70045-9

subject

Has Abstract

pub_date

2013-07-01 00:00:00

pages

1-6

eissn

0025-7753

issn

1578-8989

pii

S0025-7753(13)70045-9

journal_volume

141 Suppl 1

pub_type

杂志文章,评审
  • [Association of VCR-5FU-CYCLO-PDN in the treatment of disseminated carcinoma of the breast (author's transl)].

    abstract::A group of 32 patients with disseminated breast cancer were submitted to polychemotherapy following Cooper's protocol. Vincristine, cyclophosphamide, 5-fluorouracil, and prednisone were administered. The fifth drug used by Cooper, methotrexate, was not included in the therapy program because of difficulties in obtaini...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Estapé J,Millá A,Prats M,Herranz M,Visa J

    更新日期:1979-08-15 00:00:00

  • [The use of the potential years of life between the ages of 1 and 64 as an indicator of premature mortality in Aragón during 1987].

    abstract:BACKGROUND:Years of potential life lost (YPLL) are a health indicator which allows to discriminate the main causes of premature mortality weighting up the deaths according to the age of dead person. METHODS:Premature mortality in Aragón during 1987 is analysed by means of the indicator YPLL between the ages 1 and 64 y...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Amorin MJ,Barrasa JI,Stoduto P,Monserrat T,Arribas JL,García JR

    更新日期:1992-05-09 00:00:00

  • [Bone metabolism and fracture risk in anorexia nervosa].

    abstract::The prevalence of anorexia nervosa has increased in recent years and a large proportion of patients with this disorder have low bone density at diagnosis and, therefore, an increased risk of early and late fractures. The mechanism of bone loss in anorexia nervosa is not well understood, yet it likely includes hypogona...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审

    doi:10.1016/j.medcli.2009.04.046

    authors: Fernández Soto ML,González Jiménez A,Varsavsky M

    更新日期:2010-07-17 00:00:00

  • [Global therapy of diabetic dyslipidemia: benefits and new therapeutic approaches].

    abstract::Diabetic dyslipidemia, characterized by the lipid triad (elevated plasma triglycerides, low HDL cholesterol and predominance of small, dense LDL particles), is a significant contributor to the elevated cardiovascular risk of type 2 diabetic patients. Statin monotherapy has shown, in different prospective trials, signi...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审

    doi:10.1016/j.medcli.2009.10.010

    authors: Carmena R,Ascaso JF

    更新日期:2010-04-03 00:00:00

  • Non-alcoholic fatty liver disease: A poorly known pandemic.

    abstract::Non-alcoholic fatty liver disease (NAFLD) consists of an excessive depositing of fat in the liver, which can end up by causing inflammation, fibrosis and also cirrhosis with the corresponding complications including liver cancer. NAFLD has become the most common liver disease worldwide. The incidence has increased in ...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审

    doi:10.1016/j.medcli.2017.06.026

    authors: Augustin S,Graupera I,Caballeria J,en nombre del grupo de trabajo sobre «Hígado graso no alcohólico» de la Societat Catalana de Digestologia.

    更新日期:2017-12-20 00:00:00

  • [Prenatal diagnosis of hemoglobinopathies and thalassemias].

    abstract:BACKGROUND AND OBJECTIVE:Thalassemias are the most common single-gene disorders in the world population and the most important health problem in several countries. The best program of prevention of new births is prenatal diagnosis. Here we gather the experience from 1996 of the Spanish Group of Erythropathology related...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/j.medcli.2008.09.012

    authors: Ropero P,González FA,Hernández A,Sánchez H,Cela E,Villegas A

    更新日期:2009-01-24 00:00:00

  • [Familial aggregation of lipid and lipoprotein levels: the Cuenca study].

    abstract:BACKGROUND:The aim of this study was to assess the familial aggregation of lipid levels in schoolchildren of Cuenca city, Spain. SUBJECTS AND METHODS:A cross sectional study was made including 307 both sexes schoolchildren 9-12 years old recruited in three schools of Cuenca city, and 346 of their parents. Sociodemogra...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Martínez Vizcaíno V,Salcedo Aguilar F,Franquelo Gutiérrez R,Jarabo Crespo Y,Muelas Herráiz F,Domínguez Rojas V

    更新日期:1997-10-04 00:00:00

  • [Elderly patients with recurrent falls. Role of posturographic studies].

    abstract:BACKGROUND AND OBJECTIVE:Our purpose was to provide information about static and dynamic balance posturographic disorders in elderly people with recurrent falls, and to compare the results with a healthy elderly group. PATIENTS AND METHOD:We included 95 subjects: 57 patients who fell (86% women; age, 78.1 years) and 3...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1157/13071759

    authors: Lázaro M,Cuesta F,León A,Sánchez C,Feijoo R,Montiel M,Ribera JM

    更新日期:2005-02-19 00:00:00

  • [Consumption of sweets and snacks by a population of school children in the Autonomous Community of Madrid. The CAENPE Group].

    abstract:BACKGROUND:In our society advertising compaigns promote consumption of superfluous foods, such as sweets and snacks, displacing the intake of other basic nutrients. The aim of this study is to assess the intake of these foods by children, their relative contribution to overall macronutrient intake and their effects on ...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: López del Val T,Estivariz CF,Martínez de Icaya P,Jaunsolo MA,del Olmo D,Vázquez Martínez C

    更新日期:1997-06-14 00:00:00

  • [Comparative analysis between the use of renin-angiotensin system antagonists and clinical outcomes of hospitalized patients with COVID-19 respiratory infection].

    abstract:INTRODUCTION:Hypertension has been associated with worse outcomes in patients with COVID-19 infection, so concerns have been raised about the possibility that inhibitors of the renin-angiotensin system (RAS) could influence the prognosis of these patients. METHODS:This is an observational study of 921 consecutive pati...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/j.medcli.2020.07.004

    authors: Martínez-Del Río J,Piqueras-Flores J,Nieto-Sandoval Martín de la Sierra P,Negreira-Caamaño M,Águila-Gordo D,Mateo-Gómez C,Salas-Bravo D,Rodríguez-Martínez M

    更新日期:2020-12-11 00:00:00

  • [Liver retransplantation: outcome analysis in 50 patients].

    abstract:BACKGROUND AND OBJECTIVE:Liver re-transplantation (re-LT) is an accepted indication for some (technical problems, primary non-function [PNF]) but not all indications, particularly recurrence of the original disease, such as hepatitis C. We aimed to determine in our center: a) the rate of survival following re-transplan...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1157/13075442

    authors: Landaverde C,Berenguer M,Aguilera V,San Juan F,Prieto M,Berenguer J

    更新日期:2005-05-21 00:00:00

  • [Cerebral tuberculoma. Report of 8 cases].

    abstract::A series of eight patients with cerebral tuberculoma seen between 1980 and 1990 is reported. Headache was the leading clinical finding, followed by focal neurological findings and seizures. Papilledema was the most uniform examination finding associated with intracranial hypertension. Five patients had another localiz...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Martínez Lacasa JT,Burillo J,Niubó R,Rufí G,Podzamczer D,Mariscal A,Reñé R,Fernández Nogués F

    更新日期:1991-07-06 00:00:00

  • [Treatment of acute respiratory insufficiency in an intensive care unit (author's transl)].

    abstract::The clinical records of 304 patients with acute respiratory insufficiency were studied in retrospect. All of them had been treated in an Intensive Care Unit during its first year and a half of operation. One hundred and thirty-one patients suffered from chronic obstructive lung disease and acute episodes of chronic re...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Ibáñez Juvé J,Raurich Puigdevall JM,du Souich PB

    更新日期:1979-01-25 00:00:00

  • [Chronic fatigue syndrome associated with Epstein-Barr virus infection].

    abstract::Epstein-Barr virus (EBV) infection is ubiquitous and may result in multiple and widely different clinical features; the most common of these is infectious mononucleosis (IM). Recently, a group of patients has been included in the chronic EBV infection syndrome (EBVIS), with a sustained nonspecific syndrome consisting ...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Parras F,Salvá F,Reina J,Gil J,Portela D,Alomar P

    更新日期:1989-04-29 00:00:00

  • [Differential diagnosis of parkinsonism using dopamine transporters brain SPECT].

    abstract:BACKGROUND AND OBJECTIVE:Parkinsonism is a group of neurological disorders characterized by extrapiramidal signs. Often, the differential diagnosis between parkinsonism, essential tremor and drug-induced parkinsonism is difficult. The aim of the study was to evaluate the utility of (123I)-FP-CIT SPECT in patients with ...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/s0025-7753(04)74224-4

    authors: Lorenzo Bosquet C,Miquel Rodríguez F,Roca Bielsa I,Milà M,Aguadé Bruix S,Castell Conesa J

    更新日期:2004-03-13 00:00:00

  • [Hormonal alterations on young morbid obese women].

    abstract:BACKGROUND:Human obesity is a widespread disease with considerable variability as to its severity, metabolic and endocrine manifestations and etiology. In the present study we have determined whether the alterations of uncomplicated severe obesity in adult young women affect with different intensity the circulating lev...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/s0025-7753(01)71815-5

    authors: Vilà R,Gutiérrez R,Luisa Granada M,María Masanés R,del Mar Grasa M,Antonio Fernández López J,Remesar X,Formiguera X,Foz M,Alemany M

    更新日期:2001-03-10 00:00:00

  • [Clinical practice guideline on bipolar disorder: drug and psychosocial therapy. Asociación Española de Neuropsiquiatría].

    abstract::Bipolar disorder is a chronic and recurrent mood disorder, which may severely impact on the patient's global functioning. It has been estimated that approximately 1.6% of the population is affected. A long delay in diagnosis and an excessive disparity in the treatment of these patients have been detected. Within the Q...

    journal_title:Medicina clinica

    pub_type: 杂志文章,实务指引

    doi:10.1016/j.medcli.2013.05.023

    authors: Bravo MF,Lahera G,Lalucat L,Fernández-Liria A,en representación del Grupo Elaborador de la Guía.,Asociación Española de Neuropsiquiatría.

    更新日期:2013-10-05 00:00:00

  • [Distribution of the A(TA)7TAA genotype associated with Gilbert syndrome in the Spanish population].

    abstract:BACKGROUND:We have examined the variation in the promoter region in the gene encoding UGT-1, associated with Gilbert's syndrome, in Spanish population. PATIENTS AND METHOD:Blood DNA was obtained from 100 blood donors. Polymerase chain reaction (PCR) was used to examine the A(TA)nTAA motif in the promoter region of the...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Fernández Salazar JM,Remacha Sevilla A,del Río Conde E,Baiget Bastús M

    更新日期:2000-10-28 00:00:00

  • [Predictive capacity of the diagnostic criteria of metabolic syndrome on the insulin-resistance and the coronary risk].

    abstract:BACKGROUND AND OBJECTIVE:Since at present several diagnostic criteria of the metabolic syndrome (MS) exist, the objective of the study is to verify the utility of the criteria of the International Diabetes Federation (IDF) to diagnose the MS, their agreement with other previous definitions and the insulin resistance (I...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1157/13111806

    authors: Martínez Candela J,Franch Nadal J,Romero Ortiz J,Cánovas Domínguez C,Gallardo Martín A,López Yepes ML

    更新日期:2007-11-03 00:00:00

  • Weight and type 2 diabetes: new recommendations.

    abstract::Most patients with type 2 diabetes have excess adiposity. There is wide consensus that adequate treatment of type 2 diabetes requires a simultaneous approach to overweight/obesity and the remaining cardiovascular risk factors. Non-pharmacological interventions (diet, exercise) represent the cornerstone of the treatmen...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/S0025-7753(17)30620-6

    authors: Gómez Huelgas R

    更新日期:2016-11-01 00:00:00

  • [Prevalence of mental disorders and associated factors: results from the ESEMeD-Spain study].

    abstract:BACKGROUND AND OBJECTIVE:The ESEMeD-Spain project is an epidemiological study about mental disorders in Spain. We present 12 month-prevalence and lifetime-prevalence of the main mood, anxiety and alcohol use disorders; the influence of sociodemographic factors on its presence and age of onset of the disorders. SUBJECT...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1157/13086324

    authors: Haro JM,Palacín C,Vilagut G,Martínez M,Bernal M,Luque I,Codony M,Dolz M,Alonso J,Grupo ESEMeD-España.

    更新日期:2006-04-01 00:00:00

  • [Evaluation of the use of statistical techniques in original articles published in the Medicina Clínica during 3 decades (1962-1992)].

    abstract:BACKGROUND:The incorrect use of statistical techniques in medical articles may seriously compromise the validity of conclusions. This finding otherwise is relatively common. METHODS:A total of 84 original articles published in Medicina Clínica between 1962 and 1992 were reviewed with the aim of assessing the use and a...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: González JC,Pulido M,Sanz F

    更新日期:1995-04-01 00:00:00

  • [Role of Lactobacillus as protector against vaginal candidiasis].

    abstract:BACKGROUND:To evaluate the possible protector role of Lactobacillus against vaginal candidiasis. PATIENTS AND METHOD:In vitro studies performed to assess the capacity of 15 Lactobacillus strains to block the adhesion of two Candida albicans and one C. glabrata strain to vaginal epithelial cells and to inhibit the grow...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/s0025-7753(01)72089-1

    authors: Osset J,García E,Bartolomé RM,Andreu A

    更新日期:2001-09-22 00:00:00

  • [Study of the genetic component of cardiovascular risk phenotypes in a Mexican population].

    abstract:BACKGROUND AND OBJECTIVE:The aims of the GEMM Family Study are to clarify the genetic determinants of cardiovascular disease (CVD) risk in individuals born and living in Mexico. The authors evaluate the heritabilities (h2) of CVD risk factors in Mexicans from a preliminary cohort already studied. Heritabilities for CVD...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1157/13106675

    authors: Bastarrachea RA,Kent J Jr,Comuzzie AG

    更新日期:2007-06-02 00:00:00

  • [Prediction of patient outcome].

    abstract::Monitoring biomedical signals obtained from a patient generates information that processed conveniently, it has to allow detecting as soon as possible changes in the predicted evolution. The systematic register of one of these biomedical signals is named a time series. In this paper, a brief introduction appears to th...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审

    doi:10.1157/13057547

    authors: Muñoz Gracia MP

    更新日期:2004-01-01 00:00:00

  • [Chronic hepatitis E].

    abstract::The hepatitis E virus is an RNA virus with 4 genotypes. Genotypes 1 and 2 only affect humans and produce epidemic acute hepatitis in endemic regions (Asia and Africa). Genotypes 3 and 4 are considered a zoonosis and produce episodic acute hepatitis in non-endemic areas (America and Europe). However, in the last 3 year...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审

    doi:10.1016/j.medcli.2011.02.003

    authors: González Tallón AI,Moreira Vicente V,Mateos Lindemann ML

    更新日期:2012-02-04 00:00:00

  • [Prevalence of infections by hepatitis A, B, C and E viruses in two different socioeconomic groups of children from Santa Cruz, Bolivia].

    abstract:BACKGROUND AND OBJECTIVES:The epidemiology of hepatitis A, E, B and C was analyzed in 1,393 children living in Santa Cruz de la Sierra, Bolivia. They were distributed in two groups according to the social condition. MATERIALS AND METHOD:1,393 children were selected from two different schools: one attended by children ...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/s0025-7753(03)73826-3

    authors: Gandolfo GM,Ferri GM,Conti L,Antenucci A,Marrone R,Frasca AM,Vitelli G

    更新日期:2003-05-24 00:00:00

  • [Factors associated with mortality and gait impairment in elderly patients with hip fractures].

    abstract:BACKGROUND:Hip fractures are a major source of mortality and morbidity among the elderly. The aim of the present study is to try to identify predictors of death and of non-deambulation during the period of acute treatment. PATIENTS AND METHODS:Consecutive prospective study of 459 patients older than 65 years admitted ...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Pagès E,Cuxart A,Iborra J,Olona M,Bermejo B

    更新日期:1998-05-23 00:00:00

  • [Usefulness of PSA and its fractions in the diagnosis of prostate cancer].

    abstract:BACKGROUND AND OBJECTIVE:The description of different forms of PSA has opened a new strategy in the diagnosis of prostate cancer. The measurement of the ratio between free PSA and PSA in the group of patients with a PSA level between 4 and 10 ng/ml decreases the number of negative biopsies. The aim of our study was to ...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/s0025-7753(04)75311-7

    authors: Filella X,Truan D,Alcover J,Molina R,Luque P,Coca F,Ballesta AM

    更新日期:2004-02-28 00:00:00

  • [Sociosanitary impact on patients with rare diseases (ERES study)].

    abstract:BACKGROUND AND OBJECTIVE:The impact and burden of disease of the rare diseases (RD) is not known, also the type of disability that entail. The objective of the work is to analyze the socio-sanitary impact of the RD in Spain. PATIENTS AND METHOD:This is a nationwide study. The dimensions used were mobility, personal ca...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1157/13112096

    authors: Avellaneda Fernández A,Layola M,Izquierdo Martínez M,Guilera M,Badia Llach X,Ramón JR

    更新日期:2007-11-10 00:00:00