Neuromodulation for dystonia: target and patient selection.

Abstract:

:Treatment of dystonia refractory to oral medications or botulinum toxin injections includes the use of deep brain stimulation (DBS). Expectations should be established based on patient-related factors, including type of dystonia, genetic cause, target symptoms, age at the time of surgery, disease duration, or the presence of fixed skeletal deformities. Premorbid conditions such as psychiatric illness and cognitive impairment should be considered. Target selection is an emerging issue in DBS for dystonia. Although efficacy has been established for targeting the globus pallidus internus for dystonia, other brain targets such as the subthalamic nucleus, thalamus, or cortex may be promising alternatives.

journal_name

Neurosurg Clin N Am

authors

Mills KA,Starr PA,Ostrem JL

doi

10.1016/j.nec.2013.08.014

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

59-75

issue

1

eissn

1042-3680

issn

1558-1349

pii

S1042-3680(13)00090-9

journal_volume

25

pub_type

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