Healing of intracranial aneurysms with bioactive coils.

Abstract:

:Inadequate healing is an important mechanism for aneurysm development and recanalization after embolization. Matrix coils have been shown by experimental studies to enhance vascular repair and fibrosis, thus reducing the risk of recanalization. The clinical application of Matrix coils represents the transition from pure mechanical occlusion to adjunct biologic healing of aneurysms. Our preliminary clinical experience reveals evidence of a healing response in aneurysms treated with Matrix coils. This technology can be further improved through the incorporation of new knowledge on the molecular pathogenesis of aneurysms and the cellular and molecular mechanisms of healing.

journal_name

Neurosurg Clin N Am

authors

Feng L,Vinuela F,Murayama Y

doi

10.1016/j.nec.2005.03.001

keywords:

subject

Has Abstract

pub_date

2005-07-01 00:00:00

pages

487-99, v-vi

issue

3

eissn

1042-3680

issn

1558-1349

pii

S1042-3680(05)00021-5

journal_volume

16

pub_type

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