Human anti-F(ab')2 antibodies and pepsin agglutinators react with Fv determinants.

abstract：:An antiserum to unstimulated rat peritoneal macrophages was produced in rabbits. The antibodies were directed against an acidic protein with a molecular weight of 35,000 and with an isoelectric point at 4.6. The macrophage acidic protein (MAP) was purified by gel filtration of rat lung soluble proteins, followed by pr...

journal_title：Scandinavian journal of immunology

authors： Persson LI,Hansson E,Rönnbäck L

更新日期：1981-10-01 00:00:00

abstract：:C-reactive protein (CRP) binds to Fcγ-receptors, FcγRIIa (CD32) with high affinity and to FcγRIa (CD64) with low affinity. The binding to CD32 has been shown to be allele specific, that is, it binds to R/R131 but not to H/H131. Little is known about the cooperation of CRP and neutrophilic granulocytes (PMNs) in inflam...

journal_title：Scandinavian journal of immunology

authors： Aas V,Sand KL,Asheim HC,Benestad HB,Iversen JG

更新日期：2013-06-01 00:00:00

abstract：:Citrullination (deimination is an enzymatic, posttranslational conversion of arginine residues to citrulline residues) of joint-associated self-proteins may be a possible mechanism in the induction of autoimmune CD4 T-cell responses in rheumatoid arthritis. We have studied the immune response to normal or deiminated h...

journal_title：Scandinavian journal of immunology

authors： Rubin B,Sønderstrup G

更新日期：2004-07-01 00:00:00

abstract：:A marked prozone effect was observed in indirect immunofluorescence (IFL) with rabbit antisera against rat renal proximal tubular epithelial brush border (BB) antigens: anti-BB antibodies were not detectable if used in high concentrations but were readily demonstrated if sufficiently diluted. The prozone effect occurr...

journal_title：Scandinavian journal of immunology

authors： Linder E,Miettinen A

更新日期：1976-01-01 00:00:00

abstract：:The immunological effector mechanism responsible for the elimination of virus in murine acute non-fatal extracranial lymphocytic choriomeningitis virus infection was studied. In this infection virus clearance is generally regarded as the result of a direct action of virus-specific cytotoxic T cells (Tc cells) on virus...

journal_title：Scandinavian journal of immunology

authors： Thomsen AR,Volkert M,Bro-Jørgensen K

更新日期：1983-06-01 00:00:00

abstract：:Epstein-Barr virus (EBV)-transformed human B cells were seeded at densities below their capacity for autostimulatory growth and the effects of interleukin 1-alpha (IL-1-alpha), interleukin 1-beta (IL-1-beta) and B-cell growth factor (BCGF) were studied. When added separately, IL-1-alpha was able to support the growth ...

journal_title：Scandinavian journal of immunology

authors： Gallagher G,Taylor N,Willdridge J

更新日期：1987-09-01 00:00:00

abstract：:Based on their immunodominant nature and ability to induce appropriate immune responses in the host, several antigens of Mycobacterium tuberculosis have shown promise of protection. However, most of the candidate vaccines developed by employing various strategies have afforded protection that is at best comparable wit...

journal_title：Scandinavian journal of immunology

authors： Rao V,Dhar N,Tyagi AK

更新日期：2003-10-01 00:00:00

abstract：:The chemotactic activity in serum, defined as the attractant effect of serum on the migration of neutrophil granulocytes (PMN) has been investigated for the purpose of characterizing the major chemotactic factors in serum as measured by the leading-front technique, using a modified Boyden chamber. The chemotactic acti...

journal_title：Scandinavian journal of immunology

authors： Håkansson L,Venge P

更新日期：1984-01-01 00:00:00

abstract：:Cell surface molecules of rat normal lymphoid cells were selectively labelled by lactoperoxidase catalysed iodination or by a galactose oxidase tritiated sodium borohydride technique, subsequently detergent solubilized, isolated by indirect immunoprecipitation and analysed on SDS-polyacrylamide gel electrophoresis. Fo...

journal_title：Scandinavian journal of immunology

authors： Nilsson F,Wigzell H

更新日期：1978-04-01 00:00:00

abstract：:The present study describes a 7 amino acid-long sequence (YQQQGRL) which is identical in HLA-associated invariant chain and mumps virus nucleocapsid protein and is additionally followed by one conservative amino acid pair. As such a long amino acid homology is extremely rare in two evolutionarily unrelated proteins th...

journal_title：Scandinavian journal of immunology

authors： Hyöty H,Parkkonen P,Rode M,Bakke O,Leinikki P

更新日期：1993-05-01 00:00:00

abstract：:Peripheral blood lymphocytes from 43 patients with systemic lupus erythematosus (SLE) and from age- and sex-matched normal controls were cultured with lipopolysaccharide (LPS) to examine the response to the polyclonal B-cell activator. Lymphocytes from active SLE patients incorporated 4840 +/- 471 (mean +/- SE) cpm in...

journal_title：Scandinavian journal of immunology

authors： Abe T,Toguchi T,Takeuchi T,Kiyotaki M,Homma M

更新日期：1981-05-01 00:00:00

abstract：:Propagermanium is an organic germanium compound with immunopotentiating activity. We examined the hepatoprotective effect of propagermanium and its mechanism in an experimental animal model of acute liver injury induced with Corynebacterium parvum (C. parvum) and lipopolysaccharide (LPS) injection. Oral pretreatment w...

journal_title：Scandinavian journal of immunology

authors： Yokochi S,Ishiwata Y,Hashimoto H,Ninomiya F,Suzuki T

更新日期：1998-08-01 00:00:00

abstract：:Interleukin-15 (IL-15) is a novel IL-2-like cytokine expressed by cells of the monocyte/macrophage and epithelial lineages. Cytokines might be involved in the pathogenesis of multiple sclerosis (MS). Using immunocytochemistry, we analysed spontaneous expression of IL-15 by peripheral blood (PB) and cerebrospinal fluid...

journal_title：Scandinavian journal of immunology

authors： Pashenkov M,Mustafa M,Kivisäkk P,Link H

更新日期：1999-09-01 00:00:00

abstract：:The mammalian C-type serum lectin, mannan-binding protein (MBP), may induce C1q- and antibody-independent activation of the classical pathway of complement. Accordingly, MBP is considered as a member of the complement system. Complement deficiencies have been found with increased frequency in patients with meningococc...

journal_title：Scandinavian journal of immunology

authors： Garred P,Michaelsen TE,Bjune G,Thiel S,Svejgaard A

更新日期：1993-04-01 00:00:00

abstract：:N-Formyl peptides are cleavage products of bacterial and mitochondrial proteins that have pro-inflammatory activities and play an important role in antibacterial host defence. FcgammaRI is a receptor for the Fc portion of immunoglobulin G expressed in monocytes that mediates cytotoxicity and is upregulated by interfer...

journal_title：Scandinavian journal of immunology

authors： Beigier-Bompadre M,Barrionuevo P,Alves-Rosa F,Rubel CJ,Palermo MS,Isturiz MA

更新日期：2003-03-01 00:00:00

abstract：:Peripheral blood monocyte (PBM) subsets play different roles in inflammatory response and tissue remodelling. The aim of this study was to investigate how allergen challenge affects the number of circulating PBMs in Dermatophagoides pteronyssinus (Dp) allergic patients (Dp-APs). Among 34 Dp-APs challenged, in 22 patie...

journal_title：Scandinavian journal of immunology

authors： Kowal K,Moniuszko M,Dabrowska M,Bodzenta-Lukaszyk A

更新日期：2012-05-01 00:00:00

abstract：:Spleen cells from mice exposed to 500 rad sublethal whole-body irradiation before immunization with 100 x 10(6) allogeneic spleen cells exhibited an enhanced cytolytic T-lymphocyte (CTL) activity. In contrast, this treatment completely abrogated the humoral alloantibody response, as measured by complement-mediated lys...

journal_title：Scandinavian journal of immunology

authors： Engers HD,Louis J

更新日期：1979-01-01 00:00:00

abstract：:Two cytokines, interferon (IFN) and interleukin 2 (IL-2), activate murine natural killer (NK) cells in vitro. Together both factors synergize considerably. Antibody against IFN eliminates the response of NK cells to IFN as well as to IL-2, whereas antibody against IL-2 blocks the effect of IL-2 but not of IFN. These f...

journal_title：Scandinavian journal of immunology

authors： Chun M,Krim M,Granelli-Piperno A,Hirst JA,Hoffmann MK

更新日期：1985-10-01 00:00:00

abstract：:The in vitro immune response of lymphocytes from uraemic patients was studied by comparing the in vitro kinetics of interleukin 2 (IL-2) production, the mitogen-induced proliferative response, and the expression of IL-2 receptors by T lymphocytes. The IL-2 production in 26 uraemic cell cultures decreased significantly...

journal_title：Scandinavian journal of immunology

authors： Langhoff E,Hofmann B,Odum N,Ladefoged J,Platz P,Ryder LP,Svejgaard A

更新日期：1987-01-01 00:00:00

abstract：:MicroRNAs play an important role in the modulation of the immune system. T helper 17 (Th17) cells are involved in the modulation of the tumour microenvironment. However, the function of miRNA in Th17 cells in the tumour microenvironment is unclear. In this study, we analysed miR-132 expression in Th17 cells and assess...

journal_title：Scandinavian journal of immunology

authors： Feng R,Cui Z,Liu Z,Zhang Y

更新日期：2020-12-02 00:00:00

abstract：:Secretory component (SC) acts as a receptor for polymeric IgA (pIgA) and pIgM on the basolateral face of secretory epithelia. This study showed that both the production and surface membrane expression of SC were additively up-regulated by tumour necrosis factor-alpha (TNF) and gamma interferon (IFN-gamma) in a human c...

journal_title：Scandinavian journal of immunology

authors： Kvale D,Brandtzaeg P,Løvhaug D

更新日期：1988-09-01 00:00:00

abstract：:Subclasses of lymphocytes can be separated on gradients of non-toxic polyvinylpyrrolidone-coated colloidal silica (Percoll) by virtue of differential densities. Such gradients can yield functionally active lymphocyte populations after brief centrifugation. Gradients can be generated in a discontinuous step fashion and...

journal_title：Scandinavian journal of immunology

authors： Kurnick JT,Ostberg L,Stegagno M,Kimura AK,Orn A,Sjöberg O

更新日期：1979-01-01 00:00:00

abstract：:RadLV-Rs infection induces a murine immunodeficiency syndrome associated with a dramatic enlargement of spleen and lymph nodes. Surprisingly, the lymphoproliferation excludes thymus and Peyer's patches (PP). To understand the cellular interactions underlying lymphoproliferation further, the authors investigated the fa...

journal_title：Scandinavian journal of immunology

authors： Colombi S,Moutschen M,de Leval L,Demoitié MA,Trebak M,Martin MT,Boniver J

更新日期：1997-02-01 00:00:00

abstract：:Immunoglobulin D (IgD) is the least studied of immunoglobulin classes. This study sought to investigate the potential relationship between demographic, metabolic, lifestyle and immunological factors, and serum IgD concentrations in a general adult population. We measured serum IgD concentrations by means of a commerci...

journal_title：Scandinavian journal of immunology

authors： Carballo I,Rabuñal N,Alvela L,Pérez LF,Vidal C,Alonso M,Sopeña B,Gude F,Gonzalez-Quintela A

更新日期：2017-04-01 00:00:00

abstract：:Multifactorial involvement in the pathogenesis of autoimmune NZB/W F1 mice has been well documented. To further elucidate the role of cytokines in the disease development of murine lupus, single spleen cells isolated from NZB/W F1 and non-autoimmune C57BL/6 mice were stimulated with T cell mitogens or anti-CD3 antibod...

journal_title：Scandinavian journal of immunology

authors： Lin LC,Chen YC,Chou CC,Hsieh KH,Chiang BL

更新日期：1995-10-01 00:00:00

abstract：:Human mast cell carboxypeptidase (hMC-CP) is a unique product of mast cells. Unlike tryptase and chymase, its potential function and expression in diseased conditions remain largely unknown. To develop an assay for hMC-CP, the recombinant fusion protein of hMC-CP and purified native skin hMC-CP was prepared, and two n...

journal_title：Scandinavian journal of immunology

authors： Zhou Y,Chen Z,He S

更新日期：2006-11-01 00:00:00

abstract：:The immune system produces specific antibodies (Ab) against any antigens (Ag) of exogenous and endogenous origins with a diverse repertoire of V-region specificities. The primary V-region repertoire is created by the rearrangement of immunoglobulin (Ig) V-region, D- and J-segments with the insertion of N- and P-sequen...

journal_title：Scandinavian journal of immunology

authors： Sakaguchi N,Maeda K,Kuwahara K

更新日期：2011-06-01 00:00:00

abstract：:Using ELISA, we have quantified the levels of IL-2 and IFN-gamma in the oral mucosa, ear skin and regional and distant lymph nodes in an experimental murine model of contact sensitivity (CS), induced by the hapten oxazolone (OXA). Compared to normal conditions, the levels of IL-2 peaked early (4-6 h) after hapten expo...

journal_title：Scandinavian journal of immunology

authors： Ahlfors EE,Lyberg T

更新日期：2010-07-01 00:00:00

abstract：:Tumour-draining lymph node T cells are an excellent source of effector T cells that can be used in adoptive tumour immunotherapy because they have already been sensitized to tumour-associated antigens in vivo. However, such tumour-specific immune cells are not readily obtained from the host due to poor immunogenicity ...

journal_title：Scandinavian journal of immunology

authors： Ishida A,Tanaka H,Hiura T,Miura S,Watanabe S,Matsuyama K,Kuriyama H,Tanaka J,Kagamu H,Gejyo F,Yoshizawa H

更新日期：2007-11-01 00:00:00

abstract：:Human T lymphocytes, upon phytohaemagglutinin stimulation, are able to form colonies in semisolid media. Peripheral T cell bearing Fc receptors (TG) were studied for their possible regulatory activity on lymphoid colony development. Although no substantial differences were observed between the cloning efficiency of un...

journal_title：Scandinavian journal of immunology

authors： Canonica GW,Pistoia V,Ghio R,Mingari MC,Moretta L

更新日期：1980-01-01 00:00:00