Abstract:
RATIONALE AND OBJECTIVES:To investigate the effect of a newly developed computer-aided diagnosis (CAD) system on reader interpretation of breast lesions in automated three-dimensional (3D) breast ultrasound. MATERIALS AND METHODS:A CAD system was developed to differentiate malignant lesions from benign lesions including automated lesion segmentation in three dimensions; extraction of lesion features such as spiculation, margin contrast, and posterior acoustic behavior; and a classification stage. Eighty-eight patients with breast lesions were included for an observer study: 47 lesions were malignant and 41 were benign. Eleven readers (seven radiologists and four residents) read the cases with and without CAD. We compared the performance of readers with and without CAD using receiver operating characteristic (ROC) analysis. RESULTS:The CAD system had an area under the ROC curve (AUC) of 0.92 for discriminating benign and malignant lesions, whereas the unaided reader AUC ranged from 0.77 to 0.92. Mean performance of inexperienced readers improved when CAD was used (AUC = 0.85 versus 0.90; P = .007), whereas mean performance of experienced readers did not change with CAD (AUC = 0.89). CONCLUSIONS:By using the CAD system for classification of lesions in automated 3D breast ultrasound, which on its own performed as good as the best readers, the performance of inexperienced readers improved while that of experienced readers remained unaffected.
journal_name
Acad Radioljournal_title
Academic radiologyauthors
Tan T,Platel B,Twellmann T,van Schie G,Mus R,Grivegnée A,Mann RM,Karssemeijer Ndoi
10.1016/j.acra.2013.07.013subject
Has Abstractpub_date
2013-11-01 00:00:00pages
1381-8issue
11eissn
1076-6332issn
1878-4046pii
S1076-6332(13)00383-8journal_volume
20pub_type
杂志文章,多中心研究abstract:RATIONALE AND OBJECTIVES:The purpose of this study was to measure the effect of distractions, in the form of telephone call interruptions, on radiology resident diagnostic accuracy. MATERIALS AND METHODS:Radiology resident discrepancy reports and reading room telephone logs at an academic tertiary care pediatric hospi...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2014.08.001
更新日期:2014-12-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Diffusion tensor tractography offers a unique perspective of white matter anatomy, but proper delineation of white matter tracts of interest generally requires the active involvement of an expert neuroanatomist. The investigators describe the implementation of an automated tractographic method ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2012.01.002
更新日期:2012-05-01 00:00:00
abstract:PURPOSE:This investigation is part of a prospective National Institutes of Health-funded study evaluating three different methods for estimating the optimal length for placement of a new nasogastric (NG) tube. Abdomen radiographs were required to determine the location of the tube tip. Our objective was to analyze diff...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2012.02.007
更新日期:2012-06-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To prospectively analyze the correlation between parameters of liver perfusion from technetium99m-macroaggregates of albumin (99mTc-MAA) single photon emission computed tomography (SPECT) with those obtained from dynamic CT perfusion in patients with primary or metastatic liver malignancy. MAT...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2011.12.015
更新日期:2012-05-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Mammographic density and parenchymal patterns have been shown to be related to the risk of developing breast cancer. Thus, computerized texture analysis of breast parenchymal patterns on mammograms may be useful in assessing breast cancer risk. MATERIALS AND METHODS:A comparative evaluation wa...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2005.03.069
更新日期:2005-07-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The aim of this study was to investigate the effect of perfusion computed tomography (PCT) with acetazolamide (ACZ) challenge and compare it to 10% carbon dioxide (CO(2)) challenge in rat C6 glioma. MATERIALS AND METHODS:PCT was performed on 32 rats, including 20 with orthotopically implanted ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2011.09.017
更新日期:2012-02-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Previous cross-sectional studies have demonstrated that airway wall thickness and air trapping are greater in subjects with severe asthma than in those with mild-to-moderate asthma. However, a better understanding of how airway remodeling and lung density change over time is needed. This study ...
journal_title:Academic radiology
pub_type: 临床试验,杂志文章
doi:10.1016/j.acra.2014.05.001
更新日期:2014-08-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To evaluate cone beam computed tomography (CBCT) for monitoring of tibial bone defect healing in comparison to histopathological findings. MATERIALS AND METHODS:Circumscribed tibial bone defects were created in 16 mini-pigs and imaging of the tibia was performed on day 42 using a modern CBCT s...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2011.10.022
更新日期:2012-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Morphologic changes of the human brain during healthy aging provide useful reference knowledge for age-related brain disorders. The aim of this study was to explore age-related global and regional morphological changes of healthy adult brains. MATERIALS AND METHODS:T1-weighted magnetic resonan...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2012.03.006
更新日期:2012-07-01 00:00:00
abstract::In this article, we describe how social media can supplement traditional education, articulate the advantages and disadvantages of various social media platforms for both teachers and learners, discuss best practices to maintain confidentiality of protected health information, and provide tips for implementing social ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2016.12.023
更新日期:2017-06-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Surgeons aim to restore occlusion and jaw function to baseline status for patients with mandibular fractures using either closed treatment or reduction and fixation. MATERIALS AND METHODS:Occlusion is defined as the relationship between the maxillary and mandibular teeth as they approach each ...
journal_title:Academic radiology
pub_type: 杂志文章,评审
doi:10.1016/j.acra.2018.06.009
更新日期:2019-05-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Several methods have been proposed for estimating the standard error (SE) of the area under the curve (AUC) in receiver operating characteristic analysis. The authors examined the validity of three methods--the LABROC procedure, exponential approximation, and the method of DeLong et al (purely ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(03)80561-5
更新日期:2002-11-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The long-term prospects for patients with peripheral-arterial-occlusive disease (PAOD) must be considered in the context of coexistent generalized atherosclerosis. We sought to determine the added clinical information of noninvasive magnetic resonance imaging (MRI) for detecting asymptomatic at...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2009.08.008
更新日期:2010-02-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Studies of medical school clerkship websites have reported efficient time management, resource utilization, and hands-on activities. We built a website devoted to medical student education in radiology to address student, educator, and school curricular needs and surveyed students to assess the...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2020.08.021
更新日期:2020-09-21 00:00:00
abstract:RATIONALE AND OBJECTIVES:The authors used magnetic resonance (MR) imaging to investigate the correlation between T2* measurements of trabecular bone and the ultimate compressive strength of lumbar porcine vertebrae. METHODS:Five pigs that weighted 25-32 kg were sacrificed and imaged with a 1.5-T MR system. T2* of the ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(97)80050-5
更新日期:1997-06-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Geometrical distortion is a well-known problem in structural magnetic resonance imaging (MRI), leading to pixel shifts with variations up to several millimeters. Because the main factors of geometrical distortion are proportional to B(0), MRI spatial encoding distortions tend to increase with h...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2011.02.011
更新日期:2011-07-01 00:00:00
abstract::Quantitative imaging (QI) is increasingly applied in modern radiology practice, assisting in the clinical assessment of many patients and providing a source of biomarkers for a spectrum of diseases. QI is commonly used to inform patient diagnosis or prognosis, determine the choice of therapy, or monitor therapy respon...
journal_title:Academic radiology
pub_type: 杂志文章,评审
doi:10.1016/j.acra.2014.08.011
更新日期:2015-01-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Computed radiography provides correct optical density on film, independent of the incident radiation exposure, but it can result in under- or overexposure of the imaging plate. In the current study, we evaluated the radiation exposure trends of computed radiography over a 2-year period for port...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(96)80247-9
更新日期:1996-04-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The authors evaluated two Bayesian regression models for receiver operating characteristic (ROC) curve analysis of continuous diagnostic outcome data with covariates. MATERIALS AND METHODS:Full and partial Bayesian regression models were applied to data from two studies (n = 180 and 100, respe...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(03)80578-0
更新日期:2001-08-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Although the spiculation levels of breast mass boundaries are a primary sign of malignancy for masses detected on mammography, developing an automated computerized method to detect spiculation levels and quantitatively evaluating the performance of such a method is a difficult task. The objecti...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2008.07.015
更新日期:2008-12-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Inguinal lymph nodes can be the first or the only clinical signs of tumor metastases. The aim of the study was to evaluate the role of contrast-enhanced high-resolution magnetic resonance (MR) lymphangiography in diagnosis of inguinal lymph node metastases. MATERIALS AND METHODS:The study enro...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2012.09.014
更新日期:2013-02-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Improvements in imaging technology have led to the increased use of computed tomography (CT). For example, micro-CT and quantitative CT (QCT) are now often used in osteoporosis research, in which micro-CT is able to analyze small bones or bone samples with high spatial resolution. In contrast, ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2008.09.017
更新日期:2009-04-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The American Cancer Society (ACS) and the United States Preventive Services Task Force (USPSTF) recommend colorectal cancer (CRC) screening to begin at age 50 in individuals at average risk for CRC. To estimate rate at which women eligible for CRC screening at the time of screening mammography ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2004.07.025
更新日期:2004-11-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To quantify the use of Diagnostic Certainty Phrases (DCP) in radiology reports, including DCPs with good agreement (including "diagnostic of," "unlikely" and "represents") in connoting degree of certainty between providers based on previous studies; and to assess whether modality, presence of a...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2018.10.017
更新日期:2019-09-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To evaluate whether a computer-aided diagnosis (CADx) technique can accurately classify breast calcifications in full-field digital mammograms (FFDMs) as malignant or benign. The computer technique was developed previously on screen-film mammograms (SFMs) in which individual calcifications were...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2006.12.012
更新日期:2007-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:(23)Na magnetic resonance imaging is a promising technique for the noninvasive imaging of renal function. Past investigations of the renal corticomedullary [(23)Na] gradient have relied on imaging only in the coronal plane and on cumbersome calculations of [(23)Na], which require the use of ext...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2012.10.009
更新日期:2013-04-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The authors hypothesized that electrocardiographic triggering near end systole could minimize motion artifacts in electron-beam computed tomography (CT) of the coronary artery. MATERIALS AND METHODS:The study included 2,660 patients who underwent coronary artery calcium scanning with electron-...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/S1076-6332(03)80722-5
更新日期:2001-11-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Quantitative measurement provides essential information about disease progression and treatment response in patients with glioblastoma multiforme (GBM). The goal of this article is to present and validate a software pipeline for semi-automatic GBM segmentation, called AFINITI (Assisted Follow-u...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2012.03.026
更新日期:2012-08-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Emergency department (ED) patients with acute low back pain (LBP) may present with ambiguous clinical findings that pose diagnostic challenges to exclude cauda equina syndrome (CES). As a proof of concept, we aimed to determine the efficacy of a rapid lumbar spine (LS) magnetic resonance imagin...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2017.02.011
更新日期:2017-08-01 00:00:00
abstract::The purpose of this work is to provide current information on the rapidly evolving subject of nephrogenic systemic fibrosis (NSF), to establish the radiologic approach to the management of high-risk patients for NSF, and to assess the probabilistic risk of NSF compared to contrast induced nephropathy (CIN), as encount...
journal_title:Academic radiology
pub_type: 杂志文章,评审
doi:10.1016/j.acra.2009.01.001
更新日期:2009-07-01 00:00:00