Abstract:
RATIONALE AND OBJECTIVES:Quantitative measurement provides essential information about disease progression and treatment response in patients with glioblastoma multiforme (GBM). The goal of this article is to present and validate a software pipeline for semi-automatic GBM segmentation, called AFINITI (Assisted Follow-up in NeuroImaging of Therapeutic Intervention), using clinical data from GBM patients. MATERIALS AND METHODS:Our software adopts the current state-of-the-art tumor segmentation algorithms and combines them into one clinically usable pipeline. Both the advantages of the traditional voxel-based and the deformable shape-based segmentation are embedded into the software pipeline. The former provides an automatic tumor segmentation scheme based on T1- and T2-weighted magnetic resonance (MR) brain data, and the latter refines the segmentation results with minimal manual input. RESULTS:Twenty-six clinical MR brain images of GBM patients were processed and compared with manual results. The results can be visualized using the embedded graphic user interface. CONCLUSION:Validation results using clinical GBM data showed high correlation between the AFINITI results and manual annotation. Compared to the voxel-wise segmentation, AFINITI yielded more accurate results in segmenting the enhanced GBM from multimodality MR imaging data. The proposed pipeline could be used as additional information to interpret MR brain images in neuroradiology.
journal_name
Acad Radioljournal_title
Academic radiologyauthors
Zhu Y,Young GS,Xue Z,Huang RY,You H,Setayesh K,Hatabu H,Cao F,Wong STdoi
10.1016/j.acra.2012.03.026subject
Has Abstractpub_date
2012-08-01 00:00:00pages
977-85issue
8eissn
1076-6332issn
1878-4046pii
S1076-6332(12)00180-8journal_volume
19pub_type
杂志文章abstract:RATIONALE AND OBJECTIVES:Great expertise is necessary to mentally compile a series of individual two-dimensional image sections into a three-dimensional (3D) composite view that can aid in differential diagnosis. The purpose of this study was to test 3D volume-rendering techniques for differentiating congenital cystic ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(03)80108-3
更新日期:2003-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To evaluate the value of texture analysis on preoperative magnetic resonance imaging (MRI) for identifying nonfunctional pancreatic neuroendocrine neoplasms (NF-PNENs) and solid pseudopapillary neoplasms (SPNs). MATERIALS AND METHODS:This retrospective study included 119 patients who underwent...
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pub_type: 杂志文章
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更新日期:2020-06-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:We investigated the influence of muscular activity and regional body temperature changes on the accumulation of intravenously (i.v.) administered, dextran-coated superparamagnetic iron oxide (SPIO) particles in the lymph nodes of rats. METHODS:Four groups of rats (N = 21) were used. Five rats ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(96)80193-0
更新日期:1996-08-01 00:00:00
abstract::Health services research is a field of research that crosses many disciplines. It represents a novel way to address the Accreditation Council for Graduate Medical Education requirements for scholarly activity of residents and faculty in academic radiology departments. In addition to meeting training requirements, it o...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2013.05.007
更新日期:2013-09-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:A critical element in determining biologic behavior of pulmonary nodules is volume and temporal volume change. We evaluate variability in nodule volume among readers and measuring methods. MATERIALS AND METHODS:55 small (<2 cm) lung nodules were measured in long- and short-axis dimensions inde...
journal_title:Academic radiology
pub_type: 杂志文章
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更新日期:2005-08-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To review sustainability and fair access related to setting up a centralized transient elastography (TE) program in the radiology department and to perform a quality assessment of a novel liver fibrosis evaluation program that combines TE with limited abdominal ultrasound (US). MATERIAL AND ME...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2015.02.014
更新日期:2015-07-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:We sought to investigate the value of diffusion-weighted MR imaging in evaluating focal hepatic nodules in an experimental hepatocellular carcinoma (HCC) rat model. MATERIALS AND METHODS:Forty rats with chemically induced primary hepatic nodules ranging pathologically from regenerative nodules...
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doi:10.1016/j.acra.2006.12.005
更新日期:2007-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The purpose of this study was to determine the feasibility of using transabdominal ultrasonography (US) to monitor tumor growth and response to therapy in a mouse model of orthotopic bladder carcinoma. MATERIALS AND METHODS:Human bladder carcinoma cell suspensions were injected into the bladde...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(01)90038-8
更新日期:2001-02-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:A national needs assessment of radiology program directors was performed to characterize grand rounds (GR) programs, assess the perceived educational value of GR programs, and determine the impact of the recent economic downturn on GR. MATERIALS AND METHODS:A 28-question survey was developed q...
journal_title:Academic radiology
pub_type: 杂志文章
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更新日期:2011-12-01 00:00:00
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更新日期:1997-08-01 00:00:00
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journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2013.11.019
更新日期:2014-03-01 00:00:00
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journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(03)80345-8
更新日期:2002-07-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Previous cross-sectional studies have demonstrated that airway wall thickness and air trapping are greater in subjects with severe asthma than in those with mild-to-moderate asthma. However, a better understanding of how airway remodeling and lung density change over time is needed. This study ...
journal_title:Academic radiology
pub_type: 临床试验,杂志文章
doi:10.1016/j.acra.2014.05.001
更新日期:2014-08-01 00:00:00
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journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(00)80381-5
更新日期:2000-06-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:This study was undertaken to clarify the difference in signal pattern on contrast material-enhanced T1-weighted magnetic resonance (MR) magnetization transfer (MT) images between enhancing and nonenhancing lesions in various intracranial diseases and to determine the necessity of nonenhanced MT...
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pub_type: 杂志文章
doi:10.1016/s1076-6332(00)80116-6
更新日期:2000-03-01 00:00:00
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journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2010.04.009
更新日期:2010-09-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:This study compared the safety and efficacy of iodixanol with those of ioxaglate in adult patients undergoing aortography or peripheral arteriography. METHODS:Forty-six patients were enrolled in this controlled, randomized, double-blind, two-center study. The patients were monitored for advers...
journal_title:Academic radiology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/s1076-6332(05)80368-x
更新日期:1996-09-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Hepatic ischemia/reperfusion injury (IRI) occurs during certain hepatobiliary surgeries, hemorrhagic shock, and veno-occlusive disease. Biochemical changes caused by hepatic IRI lead to hepatocellular remodeling, including cellular regeneration or irreversible apoptosis. This study aims to char...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2010.09.019
更新日期:2011-02-01 00:00:00
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doi:10.1016/j.acra.2006.05.004
更新日期:2006-09-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.acra.2009.12.012
更新日期:2010-05-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To evaluate the sensitivity of high-resolution breast-specific gamma imaging (BSGI) for the detection of ductal carcinoma in situ (DCIS) based on histopathology and to compare the sensitivity of BSGI with mammography and magnetic resonance imaging (MRI) for the detection of DCIS. MATERIALS AND...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2007.04.004
更新日期:2007-08-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Although inflammatory breast carcinoma (IBC) accounts for 1%-4% of all breast cancer cases, the appearance of this highly malignant tumor in magnetic resonance imaging (MRI) is still not well characterized. The aim of this study was to identify typical imaging features of IBC in comparison with...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2007.09.011
更新日期:2008-02-01 00:00:00
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journal_title:Academic radiology
pub_type: 杂志文章
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更新日期:2001-05-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The aim of this study was to evaluate the intratumoral residence time of microbubbles (MBs) targeted to alpha(v)beta(3) integrin expressed in the endothelial cells of mice during the process of tumor angiogenesis. MATERIALS AND METHODS:For the preparation of MBs, decafluorobutane gas was sonic...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2009.07.017
更新日期:2010-01-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To prospectively analyze the correlation between parameters of liver perfusion from technetium99m-macroaggregates of albumin (99mTc-MAA) single photon emission computed tomography (SPECT) with those obtained from dynamic CT perfusion in patients with primary or metastatic liver malignancy. MAT...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2011.12.015
更新日期:2012-05-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Tumor grading of nonfunctional pancreatic neuroendocrine tumors (NF-pNETs) determines the choice of clinical treatment and management. The pathological grade of pancreatic neuroendocrine tumors is usually assessed on postoperative specimens. The goal of our study is to establish a tumor grade (...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2020.01.002
更新日期:2020-12-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Primary dilated cardiomyopathy is a disease of unknown etiology, and it leads to severe heart failure. Abnormalities of the cardiac metabolism can play an important role in prognosis and influence the symptomatology in this group. The aim of this study was to assess cardiac metabolism using pro...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(03)00104-1
更新日期:2003-10-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Skeletal muscle mass measurement is the most important element for diagnosing sarcopenia. MRI has an excellent soft-tissue contrast, which can non-invasively assess abdominal skeletal muscle area (SMA) as well as CT. This study aimed to assess the validity and reliability of abdominal SMA measu...
journal_title:Academic radiology
pub_type: 杂志文章
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更新日期:2020-10-28 00:00:00
abstract:RATIONALE AND OBJECTIVES:The aim of this study was to assess if graphical user interface screen-capture software applied to a magnetic resonance (MR) hardware console could nonintrusively allow the analysis of discrepancies between expected and experienced MR table time. MATERIALS AND METHODS:Individual MR examination...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2009.05.009
更新日期:2009-10-01 00:00:00
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journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2017.01.001
更新日期:2017-05-01 00:00:00