Iodixanol and ioxaglate in adult aortography and peripheral arteriography: a phase III clinical trial.

Abstract:

RATIONALE AND OBJECTIVES:This study compared the safety and efficacy of iodixanol with those of ioxaglate in adult patients undergoing aortography or peripheral arteriography. METHODS:Forty-six patients were enrolled in this controlled, randomized, double-blind, two-center study. The patients were monitored for adverse events, injection-related discomfort, and trends in laboratory data or vital signs. Diagnostic efficacy was assessed by the quality of contrast enhancement. RESULTS:All procedures were diagnostic, with no significant difference in quality of visualization (p = .205). No significant difference was seen in the number of patients experiencing mild or moderate adverse effects (p = .106). Patients receiving ioxaglate reported a significantly greater incidence of injection-related pain (p = .025). CONCLUSION:The results of this study support the conclusion that iodixanol at 320 mg I/kg is safe and effective for adult aortography and peripheral arteriography and causes significantly less injection-related pain than ioxaglate.

journal_name

Acad Radiol

journal_title

Academic radiology

authors

Rosenblum JD,Siegel EL,Leef J,Eckard DA,Lu CT

doi

10.1016/s1076-6332(05)80368-x

subject

Has Abstract

pub_date

1996-09-01 00:00:00

pages

S514-8

eissn

1076-6332

issn

1878-4046

journal_volume

3 Suppl 3

pub_type

临床试验,杂志文章,多中心研究,随机对照试验
  • Bone Marrow Lipid Profiles from Peripheral Skeleton as Potential Biomarkers for Osteoporosis: A 1H-MR Spectroscopy Study.

    abstract:RATIONALE AND OBJECTIVES:To characterize the lipidic profile of bone marrow in the calcaneus and femoral neck of healthy, osteopenic, and osteoporotic women, by using magnetic resonance spectroscopy (MRS) at 3T. The final goal was to identify specific metabolites with the potential ability to discriminate between healt...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2015.11.009

    authors: Di Pietro G,Capuani S,Manenti G,Vinicola V,Fusco A,Baldi J,Scimeca M,Hagberg G,Bozzali M,Simonetti G,Tarantino U

    更新日期:2016-03-01 00:00:00

  • Videomanometry of the pharynx in dysphagic patients with a posterior cricopharyngeal indentation.

    abstract:RATIONALE AND OBJECTIVES:Patients with a posterior indentation in the pharyngoesophageal segment (PES) are generally considered to have an abnormality of the cricopharyngeal muscle (CPM). In this study we determined the actual width of the PES and the pressure circumstances during swallowing within the pharynx and PES ...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/s1076-6332(05)80123-0

    authors: Olsson R,Ekberg O

    更新日期:1995-07-01 00:00:00

  • Area beam equalization: optimization and performance of an automated prototype system for chest radiography.

    abstract:RATIONALE AND OBJECTIVES:To evaluate the feasibility and performance of an x-ray beam equalization system for chest radiography using anthropomorphic phantoms. MATERIALS AND METHODS:Area beam equalization involves the process of the initial unequalized image acquisition, attenuator thickness calculation, mask generati...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/s1076-6332(03)00730-x

    authors: Xu T,Shikhaliev PM,Berenji GR,Tehranzadeh J,Saremi F,Molloi S

    更新日期:2004-04-01 00:00:00

  • Ex Vivo Study of Artifacts Caused by Breast Tissue Markers with Different 1.5 Tesla and 3 Tesla MRI Scanners - A Bicentric Study.

    abstract:RATIONALE AND OBJECTIVES:The purpose of our study was to evaluate magnetic resonance (MR) artifacts related to breast tissue markers in breast imaging procedures. MATERIALS AND METHODS:In this bicentric prospective ex vivo study 10 different commercially available markers were measured in self-made breast phantoms. Br...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2019.12.006

    authors: Puesken M,Unterberg-Buchwald C,Rhiem K,Große Hokamp N,Maintz D,Lotz J,Wienbeck S

    更新日期:2021-01-01 00:00:00

  • Three-dimensional volume rendering of fetal MR images for the diagnosis of congenital cystic adenomatoid malformation.

    abstract:RATIONALE AND OBJECTIVES:Great expertise is necessary to mentally compile a series of individual two-dimensional image sections into a three-dimensional (3D) composite view that can aid in differential diagnosis. The purpose of this study was to test 3D volume-rendering techniques for differentiating congenital cystic ...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/s1076-6332(03)80108-3

    authors: Hata N,Wada T,Chiba T,Tsutsumi Y,Okada Y,Dohi T

    更新日期:2003-03-01 00:00:00

  • Multidisciplinary gastrointestinal cancer clinic: abdominal radiologist as active participant.

    abstract:RATIONALE AND OBJECTIVES:Abdominal radiologists actively participated and provided subspecialty radiologic expertise in a multidisciplinary gastrointestinal cancer clinic that served a tertiary referral center. The purpose of this study was to evaluate the feasibility and nonradiologists' opinions of this new approach ...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/s1076-6332(98)80564-3

    authors: Silverman SG,Khorasani R,Adams DF,Phillips MD,Sica GT,Mayer RJ

    更新日期:1998-10-01 00:00:00

  • The Clinical Impact of Resident-attending Discrepancies in On-call Radiology Reporting: A Retrospective Assessment.

    abstract:RATIONALE AND OBJECTIVES:The purpose of this study is to quantify the clinical impact of resident-attending discrepancies at a tertiary referral academic radiology residency program by assessing rates of intervention, discrepancy confirmation, recall rate, and management change rate; furthermore, a discrepancy categori...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2017.11.016

    authors: McWilliams SR,Smith C,Oweis Y,Mawad K,Raptis C,Mellnick V

    更新日期:2018-06-01 00:00:00

  • Correlation Between Radiology ACGME Case Logs Values and ABR Core Exam Pass Rate.

    abstract:RATIONALE AND OBJECTIVES:There is discordance between the American Board of Radiology (ABR) and many radiology trainees with respect to the most appropriate means to prepare for the ABR Core Examination. Whereas the ABR suggests that participation in routine clinical examination interpretation best prepares a trainee f...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2019.10.004

    authors: Nickerson JP,Koski C,Anderson JC,Beckett B,Jackson VP

    更新日期:2020-02-01 00:00:00

  • Identification of noncalcified plaque in young persons with diabetes: an opportunity for early primary prevention of coronary artery disease identified with low-dose coronary computed tomographic angiography.

    abstract:PURPOSE:Coronary computed tomographic angiography (CTA) is a valuable tool for assessing coronary artery disease (CAD). Although statin use is widely recommended for persons with diabetes older than age 40, little is known about the presence and severity of CAD in younger patients with diabetes mellitus (DM). We evalua...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2012.03.013

    authors: Madaj PM,Budoff MJ,Li D,Tayek JA,Karlsberg RP,Karpman HL

    更新日期:2012-07-01 00:00:00

  • Face of Radiology campaign.

    abstract::This paper outlines the efforts of the American College of Radiology to understand the public perception of radiologists and to effect change in that perception. Through focus groups, in-depth interviews with Capitol Hill staff members, and national telephone surveys, it was found that the public is unaware of the edu...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2009.02.003

    authors: Neiman HL

    更新日期:2009-05-01 00:00:00

  • Healthy aging: an automatic analysis of global and regional morphological alterations of human brain.

    abstract:RATIONALE AND OBJECTIVES:Morphologic changes of the human brain during healthy aging provide useful reference knowledge for age-related brain disorders. The aim of this study was to explore age-related global and regional morphological changes of healthy adult brains. MATERIALS AND METHODS:T1-weighted magnetic resonan...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2012.03.006

    authors: Long X,Liao W,Jiang C,Liang D,Qiu B,Zhang L

    更新日期:2012-07-01 00:00:00

  • The effects of magnetically labeled rat spleen-originated endothelial progenitor cells on growth of glioma in vivo an experimental study.

    abstract:RATIONALE AND OBJECTIVES:The aim of this study was to investigate the effects of exogenous endothelial progenitor cells (EPCs) on the growth and invasiveness of glioma in vivo to provide an experimental basis for the value and safety of using magnetically labeled EPCs as target vectors to detect early infiltration of g...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2011.02.017

    authors: Fang J,Wang S,Chen J,Zhang Y,Zhang B,Liang H,Zhang W

    更新日期:2011-07-01 00:00:00

  • Thin-section CT evidence of bronchial thickening in children with stable asthma: bronchoconstriction or airway remodeling?

    abstract:RATIONALE AND OBJECTIVES:The authors performed this study to determine if bronchial wall thickening is present in children with moderate to severe asthma during periods free from clinical bronchoconstriction. MATERIALS AND METHODS:The authors obtained low (radiation) dose thin-section computed tomographic (CT) scans i...

    journal_title:Academic radiology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/S1076-6332(03)80535-4

    authors: Ketai L,Coutsias C,Williamson S,Coutsias V

    更新日期:2001-03-01 00:00:00

  • Sampling variability of nonparametric estimates of the areas under receiver operating characteristic curves: an update.

    abstract:RATIONALE AND OBJECTIVES:Several methods have been proposed for calculating the variances and covariances of nonparametric estimates of the area under receiver operating characteristic curves (AUC). The authors provide an explanation of the relationships between them and illustrate the factors that determine sampling v...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/s1076-6332(97)80161-4

    authors: Hanley JA,Hajian-Tilaki KO

    更新日期:1997-01-01 00:00:00

  • CT Pulmonary Angiography Using Automatic Tube Current Modulation Combination with Different Noise Index with Iterative Reconstruction Algorithm in Different Body Mass Index: Image Quality and Radiation Dose.

    abstract:RATIONALE AND OBJECTIVES:This study aimed to determine the appropriate body mass index (BMI)-dependent noise index (NI) setting in computed tomography pulmonary angiography (CTPA) with automatic tube current modulation with adaptive statistical iterative reconstruction (ASiR). MATERIALS AND METHODS:A total of 480 pati...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2016.07.018

    authors: Zhao YX,Zuo ZW,Suo HN,Wang JN,Chang J

    更新日期:2016-12-01 00:00:00

  • Can coronary artery anomalies be detected on CT calcium scoring studies?

    abstract:PURPOSE:To determine whether coronary artery anomalies can be detected on noncontrast computed tomography (CT) coronary artery calcium scoring (CCS) studies. MATERIALS AND METHODS:A total of 126 patients (mean age 62 years; 35 women) underwent noncontrast CCS and contrast enhanced coronary CT angiography (cCTA). Thirt...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2012.12.006

    authors: Maddux PT,Schoepf UJ,Zwerner PL,Krazinski AW,Berghaus TM,Morris PB,Thilo C

    更新日期:2013-05-01 00:00:00

  • Evaluating the effect of image preprocessing on an information-theoretic CAD system in mammography.

    abstract:RATIONALE AND OBJECTIVES:In our earlier studies, we reported an evidence-based computer-assisted decision (CAD) system for location-specific interrogation of mammograms. A content-based image retrieval framework with information theoretic (IT) similarity measures serves as the foundation for this system. Specifically, ...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2007.12.013

    authors: Tourassi GD,Ike R 3rd,Singh S,Harrawood B

    更新日期:2008-05-01 00:00:00

  • The "Look Ahead" Technique: A Novel Way to Engage Medical Students in the Radiology Reading Room.

    abstract:RATIONALE AND OBJECTIVES:Engaging medical students during a radiology course can be challenging. We sought a way to actively engage students with live cases, allow them to interact with the picture archiving and communication system workstation, and experience what it is like to be a radiologist. MATERIALS AND METHODS...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2019.12.021

    authors: Huang J,Bingham B,Jordanov M

    更新日期:2021-02-01 00:00:00

  • Clinical Applications of DSC-MRI Parameters Assess Angiogenesis and Differentiate Malignant From Benign Soft Tissue Tumors in Limbs.

    abstract:OBJECTIVE:To investigate the correlation between dynamic susceptibility contrast magnetic resonance imaging (DSC-MRI) parameters and angiogenesis and to explore prospectively the feasibility of using DSC-MRI to differentiate malignant from benign soft tissue tumors (STTs) in limbs. METHODS:This prospective study inclu...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2019.04.023

    authors: Bian Y,Jin P,Wang Y,Wei X,Qiang Y,Niu G,Jin G,Yang J

    更新日期:2020-03-01 00:00:00

  • Full field digital mammography and breast density: comparison of calibrated and noncalibrated measurements.

    abstract:RATIONALE AND OBJECTIVES:Mammographic breast density is an important and widely accepted risk factor for breast cancer. A statement about breast density in the mammographic report is becoming a requirement in many States. However, there is significant inter-observer variation between radiologists in their interpretatio...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2011.07.011

    authors: Heine JJ,Fowler EE,Flowers CI

    更新日期:2011-11-01 00:00:00

  • Determining optimal acquisition parameters for computed tomography coronary angiography: evaluation of a software-assisted, breathhold exam simulation.

    abstract:RATIONALE AND OBJECTIVES:Scanning parameters used in multislice computed tomographic (MSCT) coronary angiography should be adapted to patients' heart rates. The aim of this study was to evaluate the rate of success of a software-assisted scan simulation to determine optimal gantry rotation time prior to MSCT coronary a...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2008.08.016

    authors: Engelken FJ,Lembcke A,Hamm B,Dewey M

    更新日期:2009-02-01 00:00:00

  • NCI image archive management workshop: a preliminary report.

    abstract::The National Cancer Institute organized a workshop entitled "Image Archive Management" that was presented on August 28 and 29, 2000, at the Natcher Conference Center on the National Institutes of Health (NIH) campus. The purpose of this workshop was to solicit expert input for the planned development of an archival sy...

    journal_title:Academic radiology

    pub_type:

    doi:10.1016/S1076-6332(03)80699-2

    authors: Staab E,Clarke LP,Baker H,Sullivan D

    更新日期:2001-07-01 00:00:00

  • Comparison of radiation dose estimates and scan performance in pediatric high-resolution thoracic CT for volumetric 320-detector row, helical 64-detector row, and noncontiguous axial scan acquisitions.

    abstract:RATIONALE AND OBJECTIVES:Efforts to decrease radiation exposure during pediatric high-resolution thoracic computed tomography (HRCT), while maintaining diagnostic image quality, are imperative. The objective of this investigation was to compare organ doses and scan performance for pediatric HRCT using volume, helical, ...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2013.05.013

    authors: Podberesky DJ,Angel E,Yoshizumi TT,Toncheva G,Salisbury SR,Brody AS,Alsip C,Barelli A,Egelhoff JC,Anderson-Evans C,Nguyen GB,Dow D,Frush DP

    更新日期:2013-09-01 00:00:00

  • Marking of small pulmonary nodules before thoracoscopic resection: injection of lipiodol under CT-fluoroscopic guidance.

    abstract:RATIONALE AND OBJECTIVES:The aim of the present study was to examine the usefulness and record the complications of preoperative lipiodol marking using computed tomographic (CT) fluoroscopy for the intraoperative localization of 107 pulmonary nodules. METHODS:Lipiodol marking was performed under CT fluoroscopic guidan...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2008.07.012

    authors: Kawanaka K,Nomori H,Mori T,Ikeda K,Ikeda O,Tomiguchi S,Yamashita Y

    更新日期:2009-01-01 00:00:00

  • CT detection of serious internal and skeletal injuries in patients with pelvic fractures.

    abstract:RATIONALE AND OBJECTIVES:The purpose of this study was to determine the percentage of patients with known pelvic fractures who have additional findings of intraabdominal injury, as diagnosed at abdominal computed tomography (CT), and to determine if patients with specific types or patterns of fractures are more likely ...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/S1076-6332(99)80209-8

    authors: Killeen KL,DeMeo JH

    更新日期:1999-04-01 00:00:00

  • Computed radiography and film digitizer inputs to an intensive care unit teleradiology system: an image quality comparison.

    abstract:RATIONALE AND OBJECTIVES:We compared computed radiography (CR) with a film digitizer as an image input device for transmitting radiographs to intensive care unit (ICU) displays. METHODS:Limiting spatial resolution and low-contrast detectability performance were determined for a 600-speed screen-film combination and CR...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/s1076-6332(05)80375-7

    authors: Huda W,Honeyman JC,Palmer CK,Frost MM,Staab EV

    更新日期:1996-02-01 00:00:00

  • Design considerations for using PET as a response measure in single site and multicenter clinical trials.

    abstract:RATIONALE AND OBJECTIVES:Positron emission tomography (PET) is used to evaluate response to therapy with increasing interest in having PET provide endpoints for clinical trials. Here we demonstrate impacts of PET measurement error and choice of quantification method on clinical trial design. MATERIALS AND METHODS:Samp...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2011.10.008

    authors: Doot RK,Kurland BF,Kinahan PE,Mankoff DA

    更新日期:2012-02-01 00:00:00

  • Magnetic resonance lymphography in rats: effects of muscular activity and hyperthermia on the lymph node uptake of intravenously injected superparamagnetic iron oxide particles.

    abstract:RATIONALE AND OBJECTIVES:We investigated the influence of muscular activity and regional body temperature changes on the accumulation of intravenously (i.v.) administered, dextran-coated superparamagnetic iron oxide (SPIO) particles in the lymph nodes of rats. METHODS:Four groups of rats (N = 21) were used. Five rats ...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/s1076-6332(96)80193-0

    authors: Elste V,Wagner S,Taupitz M,Pfefferer D,Kresse M,Hamm B,Berg R,Wolf KJ,Semmler W

    更新日期:1996-08-01 00:00:00

  • Reproducibility of five anorectal morphologic measurements in defecography.

    abstract:RATIONALE AND OBJECTIVES:We evaluated the inter- and intraobserver reproducibility of measuring five morphologic parameters of the anorectum in defecography (evacuation proctography). METHODS:Measurements from 42 defecographic studies were statistically analyzed. The parameters measured during resting, squeezing, and ...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/s1076-6332(05)80719-6

    authors: Yang X,Partanen K,Farin P,Ji H,Soimakallio S

    更新日期:1994-11-01 00:00:00

  • When and why might a computer-aided detection (CAD) system interfere with visual search? An eye-tracking study.

    abstract:RATIONAL AND OBJECTIVES:Computer-aided detection (CAD) systems are intended to improve performance. This study investigates how CAD might actually interfere with a visual search task. This is a laboratory study with implications for clinical use of CAD. METHODS:Forty-seven naive observers in two studies were asked to ...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2012.05.013

    authors: Drew T,Cunningham C,Wolfe JM

    更新日期:2012-10-01 00:00:00