Abstract:
RATIONALE AND OBJECTIVES:The long-term prospects for patients with peripheral-arterial-occlusive disease (PAOD) must be considered in the context of coexistent generalized atherosclerosis. We sought to determine the added clinical information of noninvasive magnetic resonance imaging (MRI) for detecting asymptomatic atherosclerotic disease in patients already at high risk. MATERIALS AND METHODS:Eighty-four patients (64 men, mean age 66.2 + or - 10.0 years, range 34-84 years) with suspected or known PAOD were examined using a comprehensive cardiovascular MRI protocol. Two experienced observers reviewed all MRIs for the presence of "relevant findings," which were defined as pathology requiring immediate therapy or mid-term follow-up. RESULTS:Assessment of cardiac structures and function in 84 study patients yielded new pathology in 40 (48%) patients, whereas cerebral imaging revealed new findings in 45 (54%) patients. Previously unsuspected vascular findings were evident in 46 (55%) patients. Using the information from the MRIs, in 54 (64%) of patients mid-term follow-up was required, whereas in 7 (8%) patients a change of therapy or immediate treatment was necessary. CONCLUSION:Whole-body cardiovascular MRI is able to detect symptomatic and unsuspected findings in patients with PAOD. This technique was able to detect several vascular abnormalities that necessitated immediate medical attention and intervention in patients already identified as high-risk patients and, therefore, may show an increasing impact to determine individual therapeutic and follow-up concepts.
journal_name
Acad Radioljournal_title
Academic radiologyauthors
Fenchel M,Scheule AM,Kramer U,Bretschneider C,Klumpp B,Seeger A,Rittig K,Claussen CD,Miller Sdoi
10.1016/j.acra.2009.08.008subject
Has Abstractpub_date
2010-02-01 00:00:00pages
219-29issue
2eissn
1076-6332issn
1878-4046pii
S1076-6332(09)00493-0journal_volume
17pub_type
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journal_title:Academic radiology
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journal_title:Academic radiology
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