Abstract:
RATIONALE AND OBJECTIVES:To evaluate whether a computer-aided diagnosis (CADx) technique can accurately classify breast calcifications in full-field digital mammograms (FFDMs) as malignant or benign. The computer technique was developed previously on screen-film mammograms (SFMs) in which individual calcifications were identified manually. The present study evaluated the computer technique independently on a new database of FFDM images with automatic detection of the individual calcifications. MATERIALS AND METHODS:We analyzed 49 consecutive FFDM cases (19 cancers) that showed suspicious calcifications. Four mammography radiologists read soft-copy mammograms retrospectively and electronically indicated the region of calcifications in each image. The computer then automatically detected the individual calcifications within the indicated region and analyzed eight features of calcification morphology and distribution to arrive at an estimated likelihood of malignancy. The radiologists entered Breast Imaging Report and Data System assessments before and after seeing the computer results. Performance was analyzed using receiver operating characteristic analysis. RESULTS:Despite variability in radiologist-indicated regions of calcifications, the computer achieved consistently high performance taking input from the four radiologists (receiver operating characteristic curve area, A(z): 0.80, 0.80, 0.78, and 0.77; differences not statistically significant). Previous results showed that the computer technique achieved an A(z) value of 0.80 on SFMs, which improved radiologists' performance significantly. CONCLUSIONS:The computer technique appears to maintain consistently high performance in classifying calcifications in FFDMs as malignant or benign without requiring substantial modification from its initial development on SFMs. The computer performance appears to be robust with respect to variations in radiologists' input.
journal_name
Acad Radioljournal_title
Academic radiologyauthors
Rana RS,Jiang Y,Schmidt RA,Nishikawa RM,Liu Bdoi
10.1016/j.acra.2006.12.012subject
Has Abstractpub_date
2007-03-01 00:00:00pages
363-70issue
3eissn
1076-6332issn
1878-4046pii
S1076-6332(06)00726-4journal_volume
14pub_type
杂志文章abstract:RATIONALE AND OBJECTIVES:The goal of this study is to demonstrate how the teaching of radiology physics can be enhanced with the use of interactive scientific notebook software. METHODS:We used the scientific notebook software known as Project Jupyter, which is free, open-source, and available for the Macintosh, Windo...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2017.11.024
更新日期:2018-06-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Catheter-directed intraarterial (IA) injections of gadolinium contrast agents may be used during endovascular interventions with magnetic resonance (MR) imaging guidance. Injection protocols require further validation. Using a flow phantom and swine, the authors aimed to (a) measure the optimal...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(03)80167-8
更新日期:2002-02-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The purpose of this multicenter, multireader study was to evaluate the performance of computed tomography (CT) lung nodule computer-aided detection (CAD) software as a second reader. METHODS AND MATERIALS:The study involved 109 patients from four sites. The data were collected from a variety o...
journal_title:Academic radiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.acra.2007.09.027
更新日期:2008-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The aim of this study was to evaluate the predictive value of intraluminal air for appendiceal necrosis and/or perforation when not apparent on imaging. Additional factors of intraluminal appendicoliths, age, and gender were also assessed. MATERIALS AND METHODS:Patients with pathologically pro...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2012.04.018
更新日期:2012-10-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The study aimed to investigate the positive predictive value (PPV) of mammographic lymphography (MLG) for assessing malignant breast disease and lymphatic metastasis in patients in a typical clinical setting. MATERIALS AND METHODS:Patients who underwent mammography with Breast Imaging Reportin...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2016.05.001
更新日期:2016-10-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The authors performed this study to determine the optimum threshold for performing computed tomographic (CT) angiography with shaded surface display (SSD). MATERIALS AND METHODS:A dedicated phantom was developed with an 8-mm luminal diameter. Each of 19 vessels had stenoses ranging from 0% to ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/S1076-6332(03)80641-4
更新日期:2001-10-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The aim of this study was to determine the optimal arterial phase delay for computed tomography imaging of hepatocellular carcinoma (HCC) before and after transarterial chemoembolization (TACE) using a low iodine dose protocol. MATERIALS AND METHODS:A total of 39 patients with known HCC were i...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2015.08.021
更新日期:2015-12-01 00:00:00
abstract::Teaching and assessing trainees' professionalism now represents an explicit expectation for Accreditation Council Graduate Medical Education-accredited radiology programs. Challenges to meeting this expectation include variability in defining the construct of professionalism; limits of traditional teaching and assessm...
journal_title:Academic radiology
pub_type: 杂志文章,评审
doi:10.1016/j.acra.2018.01.008
更新日期:2018-05-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:We evaluated the effect of gravity on intrahepatic perfusion (IHP) in patients with a port-catheter system (PCS) implanted for hepatic arterial infusion chemotherapy (HAIC). Using fused single photon-emission computed tomographic (SPECT)/computed tomographic (CT) images, we compared IHP after t...
journal_title:Academic radiology
pub_type: 临床试验,杂志文章
doi:10.1016/j.acra.2008.12.004
更新日期:2009-06-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:We studied preparatory strategies for high-resolution human eye in vivo imaging with commercially available magnets and coils. MATERIALS AND METHODS:We imaged normal volunteers on 1.5T systems by Philips, GE, and Siemens, using commercial approximately 9 cm temporomandibular joint receive coil...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2005.10.023
更新日期:2006-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Amphiphilic biocompatible polyoxyethylene (PEO)-based polymers form particles (micelles) that are 10-50 nm in diameter. In the current research, we successfully incorporated amphiphilic indium-111 (111In) and gadolinium chelates into these particles and used them as particulate contrast media i...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(96)80448-x
更新日期:1996-03-01 00:00:00
abstract::Disturbances in blood capillary exchange of fluid, macromolecules, and cells across intact and abnormal microvessels and deranged lymphatic transport are integral, interacting components in disorders of tissue swelling. Lymphedema or low-output failure of the lymph circulation is often indolent for many years before l...
journal_title:Academic radiology
pub_type: 杂志文章,评审
doi:10.1016/s1076-6332(05)80193-x
更新日期:1995-04-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Computed radiography provides correct optical density on film, independent of the incident radiation exposure, but it can result in under- or overexposure of the imaging plate. In the current study, we evaluated the radiation exposure trends of computed radiography over a 2-year period for port...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(96)80247-9
更新日期:1996-04-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:We compared computed radiography (CR) with a film digitizer as an image input device for transmitting radiographs to intensive care unit (ICU) displays. METHODS:Limiting spatial resolution and low-contrast detectability performance were determined for a 600-speed screen-film combination and CR...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(05)80375-7
更新日期:1996-02-01 00:00:00
abstract::The role of positron emission tomography (PET) during the past decade has evolved rapidly from that of a pure research tool to a methodology of enormous clinical potential. (18)F-fluorodeoxyglucose (FDG)-PET is currently the most widely used probe in the diagnosis, staging, assessment of tumor response to treatment, a...
journal_title:Academic radiology
pub_type: 杂志文章,评审
doi:10.1016/j.acra.2009.02.014
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND:The use of cardiac computed tomography (cardiac CT) and the quantification of the Agatston score for the evaluation of calcium of the aortic valve (AVC) has increased in different clinical contexts for diagnostic and prognostic purposes. This study aims to evaluate the correlation between cardiac CT and hist...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2020.12.015
更新日期:2021-01-14 00:00:00
abstract:RATIONALE AND OBJECTIVES:To evaluate the ex vivo ablation zones created in hepatic tissue using monopolar and bipolar gas- and water-cooled radiofrequency (RF) applicators. MATERIALS AND METHODS:RF ablations were performed on ex vivo bovine liver tissue using closed circuit water-cooled and closed circuit cryogenicall...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2014.02.004
更新日期:2014-05-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To retrospectively analyze the chest imaging findings in patients with coronavirus disease 2019 (COVID-19) on thin-section CT. MATERIALS AND METHODS:Fifty-three patients with confirmed COVID-19 infection underwent thin-section CT examination. Two chest radiologists independently evaluated the ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2020.03.002
更新日期:2020-05-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Malignancy provokes regional changes to vessel shape. Characteristic vessel tortuosity abnormalities appear early during tumor development, affect initially healthy vessels, spread beyond the confines of tumor margins, and do not simply mirror tissue perfusion. The ability to detect and quantif...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2005.05.027
更新日期:2005-10-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Most radiographic contrast media are hyperosmotic and able to shrink cells with which they are in contact. The authors studied cell volume control in rabbit proximal renal tubules after incubation with three contrast media: iohexol, ioxaglate, and iodixanol. MATERIALS AND METHODS:Proximal rena...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/S1076-6332(03)80547-0
更新日期:2001-05-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:We examined whether high-resolution computed tomography (HRCT) would detect and quantify induced airway changes in asthmatic volunteers. METHODS:We performed pulmonary function tests and HRCT on eight asthmatic adults and two nonasthmatic control adults under three conditions: baseline, after ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(05)80671-3
更新日期:1996-05-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Extraprostatic extension of disease (EPE) has a major role in risk stratification of prostate cancer patients. Currently, pretreatment local staging is performed with MRI, while the gold standard is represented by histopathological analysis after radical prostatectomy. Texture analysis (TA) is ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2018.12.025
更新日期:2019-10-01 00:00:00
abstract:RATIONAL AND OBJECTIVES:This study aims to evaluate the diagnostic utility of breast imaging using transmission ultrasound. We present readers' accuracy in determining whether a breast lesion is a cyst versus a solid using transmission ultrasound as an adjunct to mammography. MATERIALS AND METHODS:This retrospective m...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2017.03.024
更新日期:2017-09-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:This study compared the safety and efficacy of iodixanol with those of ioxaglate in adult patients undergoing aortography or peripheral arteriography. METHODS:Forty-six patients were enrolled in this controlled, randomized, double-blind, two-center study. The patients were monitored for advers...
journal_title:Academic radiology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/s1076-6332(05)80368-x
更新日期:1996-09-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:We examined the status of women's representation on radiology journal editorial boards around the world and evaluated temporal trends in female board representation. MATERIALS AND METHODS:Data on the gender of editorial board members, deputy editors, and editors-in-chief of top general radiolo...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2020.07.004
更新日期:2020-08-08 00:00:00
abstract:RATIONALE AND OBJECTIVES:To report the detection rate for lung cancers in computed tomography (CT) screening in Japanese adults, and to analyze differences in the appearance of the cancers in non-smokers versus smokers. MATERIALS AND METHODS:Subjects consisted of 7,847 Japanese adults who received low-dose CT screenin...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(03)00150-8
更新日期:2003-09-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Breast segmentation using the U-net architecture was implemented and tested in independent validation datasets to quantify fibroglandular tissue volume in breast MRI. MATERIALS AND METHODS:Two datasets were used. The training set was MRI of 286 patients with unilateral breast cancer. The segme...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2019.01.012
更新日期:2019-11-01 00:00:00
abstract:OBJECTIVE:This study was to investigate the CT quantification of COVID-19 pneumonia and its impacts on the assessment of disease severity and the prediction of clinical outcomes in the management of COVID-19 patients. MATERIALS METHODS:Ninety-nine COVID-19 patients who were confirmed by positive nucleic acid test (NAT...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2020.09.004
更新日期:2020-12-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Intravenous thrombolysis decision-making and obtaining of consent would be assisted by an individualized risk-benefit ratio. Deep learning (DL) models may be able to assist with this patient selection. MATERIALS AND METHODS:Clinical data regarding consecutive patients who received intravenous ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2019.03.015
更新日期:2020-02-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To better prepare radiology residents for providing care within the context of the larger health care system, this study evaluated the feasibility and impact of a curriculum to enhance radiology residents' understanding and ability to apply concepts from medical management and industrial and op...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2012.09.025
更新日期:2013-03-01 00:00:00