当前位置： SCI文献检索 > ACADEMIC RADIOLOGY期刊下所有文献 > Automatic Breast and Fibroglandular Tissue Segmentation in Breast MRI Using Deep Learning by a Fully-Convolutional Residual Neural Network U-Net.

Automatic Breast and Fibroglandular Tissue Segmentation in Breast MRI Using Deep Learning by a Fully-Convolutional Residual Neural Network U-Net.

Abstract：

RATIONALE AND OBJECTIVES:Breast segmentation using the U-net architecture was implemented and tested in independent validation datasets to quantify fibroglandular tissue volume in breast MRI. MATERIALS AND METHODS:Two datasets were used. The training set was MRI of 286 patients with unilateral breast cancer. The segmentation was done on the contralateral normal breasts. The ground truth for the breast and fibroglandular tissue (FGT) was obtained by using a template-based segmentation method. The U-net deep learning algorithm was implemented to analyze the training set, and the final model was obtained using 10-fold cross-validation. The independent validation set was MRI of 28 normal volunteers acquired using four different MR scanners. Dice Similarity Coefficient (DSC), voxel-based accuracy, and Pearson's correlation were used to evaluate the performance. RESULTS:For the 10-fold cross-validation in the initial training set of 286 patients, the DSC range was 0.83-0.98 (mean 0.95 ± 0.02) for breast and 0.73-0.97 (mean 0.91 ± 0.03) for FGT; and the accuracy range was 0.92-0.99 (mean 0.98 ± 0.01) for breast and 0.87-0.99 (mean 0.97 ± 0.01) for FGT. For the entire 224 testing breasts of the 28 normal volunteers in the validation datasets, the mean DSC was 0.86 ± 0.05 for breast, 0.83 ± 0.06 for FGT; and the mean accuracy was 0.94 ± 0.03 for breast and 0.93 ± 0.04 for FGT. The testing results for MRI acquired using four different scanners were comparable. CONCLUSION:Deep learning based on the U-net algorithm can achieve accurate segmentation results for the breast and FGT on MRI. It may provide a reliable and efficient method to process large number of MR images for quantitative analysis of breast density.

journal_name

Acad Radiol

journal_title

Academic radiology

authors

Zhang Y,Chen JH,Chang KT,Park VY,Kim MJ,Chan S,Chang P,Chow D,Luk A,Kwong T,Su MY

doi

10.1016/j.acra.2019.01.012

subject

Has Abstract

pub_date

2019-11-01 00:00:00

pages

1526-1535

issue

eissn

1076-6332

issn

1878-4046

pii

S1076-6332(19)30036-4

journal_volume

pub_type

杂志文章

在线工具

Automatic Breast and Fibroglandular Tissue Segmentation in Breast MRI Using Deep Learning by a Fully-Convolutional Residual Neural Network U-Net.