当前位置： SCI文献检索 > ACADEMIC RADIOLOGY期刊下所有文献 > Lung nodule CAD software as a second reader: a multicenter study.

Lung nodule CAD software as a second reader: a multicenter study.

Abstract：

RATIONALE AND OBJECTIVES:The purpose of this multicenter, multireader study was to evaluate the performance of computed tomography (CT) lung nodule computer-aided detection (CAD) software as a second reader. METHODS AND MATERIALS:The study involved 109 patients from four sites. The data were collected from a variety of multidetector CT scanners and had different scan parameters. Each chest CT scan was divided into four quadrants. A group of three expert thoracic radiologists identified nodules between 4 and 30 mm in maximum diameter within each quadrant. The standard of reference was established by a consensus read of these experienced radiologists. The cases were then interpreted by 10 other radiologist readers with varying degrees of experience, without and then with CAD software. These readers identified nodules and assigned an actionability rating to each quadrant before and after using CAD software. Receiver operating characteristic curves were used to measure the performance of the readers without and with CAD software. RESULTS:The average increase in area under the curve for the 10 readers with CAD software was 1.9% for a 95% confidence interval (0.8-8.0%). The area under the curve without CAD software was 86.7% and with CAD software was 88.7%. A nonsignificant correlation was observed between the improvement in sensitivity and experience of the radiologists. The readers also showed a greater improvement in patients with cancer as compared to those without cancer. CONCLUSIONS:In this multicenter trial, CAD software was shown to be effective as a second reader by improving the sensitivity of the radiologists in detecting pulmonary nodules.

journal_name

Acad Radiol

journal_title

Academic radiology

authors

White CS,Pugatch R,Koonce T,Rust SW,Dharaiya E

doi

10.1016/j.acra.2007.09.027

subject

Has Abstract

pub_date

2008-03-01 00:00:00

pages

326-33

issue

3

eissn

1076-6332

issn

1878-4046

pii

S1076-6332(07)00582-X

journal_volume

15

pub_type

杂志文章,多中心研究

相关文献

ACADEMIC RADIOLOGY文献大全
  • Modified Subtraction Coronary CT Angiography Method for Patients Unable to Perform Long Breath-Holds: A Preliminary Study.

    abstract：RATIONALE AND OBJECTIVES:Severe calcifications of the coronary arteries are still a major challenge in coronary computed tomography (CT) angiography (CCTA). Subtraction CCTA using a 320-detector row CT scanner has recently been introduced for patients with severe calcifications. However, the conventional subtraction CC...

    journal_title：Academic radiology

    pub_type： 杂志文章

    doi：10.1016/j.acra.2016.04.012

    authors： Yoshioka K,Tanaka R,Nagata K,Sasaki T,Takeda K,Ueda T,Sugawara T,Ueyama Y,Chiba T,Sasaki A,Kikuchi K

    更新日期：2016-09-01 00:00:00

  • Thin-section CT evidence of bronchial thickening in children with stable asthma: bronchoconstriction or airway remodeling?

    abstract：RATIONALE AND OBJECTIVES:The authors performed this study to determine if bronchial wall thickening is present in children with moderate to severe asthma during periods free from clinical bronchoconstriction. MATERIALS AND METHODS:The authors obtained low (radiation) dose thin-section computed tomographic (CT) scans i...

    journal_title：Academic radiology

    pub_type： 杂志文章,多中心研究

    doi：10.1016/S1076-6332(03)80535-4

    authors： Ketai L,Coutsias C,Williamson S,Coutsias V

    更新日期：2001-03-01 00:00:00

  • Assessment of intraaxial and extraaxial brain lesions with digitized computed tomographic images versus film: ROC analysis.

    abstract：RATIONALE AND OBJECTIVES:The authors evaluated the diagnostic accuracy of viewing computed tomographic (CT) scans as film versus soft-copy images at a workstation. METHODS:Receiver operating characteristic analysis of the interpretation of 202 CT scans (103 were normal, 99 were abnormal) by five neuroradiologists was ...

    journal_title：Academic radiology

    pub_type： 杂志文章

    doi：10.1016/s1076-6332(97)80004-9

    authors： el-Saden SM,Hademenos GJ,Zhu W,Sayre JW,Glenn B,Steidler J,Kode L,King B,Quinones D,Valentino DJ,Bentson JR

    更新日期：1997-02-01 00:00:00

  • Increased epicardial, pericardial, and subcutaneous adipose tissue is associated with the presence and severity of coronary artery calcium.

    abstract：RATIONALE AND OBJECTIVES:Epicardial adipose tissue (EAT), pericardial adipose tissue (PAT), and subcutaneous adipose tissue (SAT) are mediators of metabolic risk and may be involved in the pathogenesis of coronary artery disease. The aim of this study was to investigate the association of visceral and subcutaneous fat ...

    journal_title：Academic radiology

    pub_type： 杂志文章

    doi：10.1016/j.acra.2010.08.017

    authors： Ahmadi N,Nabavi V,Yang E,Hajsadeghi F,Lakis M,Flores F,Zeb I,Bevinal M,Ebrahimi R,Budoff M

    更新日期：2010-12-01 00:00:00

  • Part I: preparing first-year radiology residents and assessing their readiness for on-call responsibilities.

    abstract：RATIONALE AND OBJECTIVES:The aim of the study is to evaluate the effectiveness of an Emergency Radiology (ER) Core Curriculum training module and a Digital Imaging and Communications in Medicine (DICOM)-based interactive examination system to prepare first-year (postgraduate year 2 [PGY-2]) radiology residents and asse...

    journal_title：Academic radiology

    pub_type： 杂志文章

    doi：10.1016/j.acra.2006.02.057

    authors： Ganguli S,Pedrosa I,Yam CS,Appignani B,Siewert B,Kressel HY

    更新日期：2006-06-01 00:00:00

  • Theory-based signal calibration with single-point T1 measurements for first-pass quantitative perfusion MRI studies.

    abstract：RATIONALE AND OBJECTIVES:The aim of the study is to develop a theory-based signal calibration approach to be used for the conversion of signal-time curves to absolute contrast concentration-time curves for first-pass contrast-enhanced quantitative myocardial perfusion studies. MATERIALS AND METHODS:A normalization pro...

    journal_title：Academic radiology

    pub_type： 杂志文章

    doi：10.1016/j.acra.2006.02.040

    authors： Cernicanu A,Axel L

    更新日期：2006-06-01 00:00:00

  • Relating dose of contrast media administered to uptake and washout of malignant lesions on DCEMRI of the breast.

    abstract：RATIONALE AND OBJECTIVES:To quantify the relationship between dose of contrast administered and contrast kinetics of malignant breast lesions. MATERIALS AND METHODS:A total of 108 patients with 120 malignant lesions were selected for an institutional review board-approved review. Dynamic magnetic resonance protocol: o...

    journal_title：Academic radiology

    pub_type： 杂志文章

    doi：10.1016/j.acra.2009.06.015

    authors： Jansen SA,Fan X,Yang C,Shimauchi A,Karczmar G,Newstead GM

    更新日期：2010-01-01 00:00:00

  • Registering histologic and MR images of prostate for image-based cancer detection.

    abstract：RATIONALE AND OBJECTIVES:Needle biopsy is currently the only way to confirm prostate cancer. To increase prostate cancer diagnostic rate, needles are expected to be deployed at suspicious cancer locations. High-contrast magnetic resonance (MR) imaging provides a powerful tool for detecting suspicious cancerous tissues....

    journal_title：Academic radiology

    pub_type： 杂志文章

    doi：10.1016/j.acra.2007.07.018

    authors： Zhan Y,Ou Y,Feldman M,Tomaszeweski J,Davatzikos C,Shen D

    更新日期：2007-11-01 00:00:00

  • Loss of anteroposterior intralobar attenuation gradient of the lung: Correlation with pulmonary function.

    abstract：RATIONALE AND OBJECTIVES:Since the initial description of an intralobar attenuation gradient by Webb et al, it has been suggested that departure from the intralobar attenuation gradient could indicate early lung diseases. However, its significance has not been determined in detail. We aimed to quantify the anteroposter...

    journal_title：Academic radiology

    pub_type： 杂志文章

    doi：10.1016/j.acra.2005.10.025

    authors： Nishino M,Roberts DH,Sitek A,Raptopoulos V,Boiselle PM,Hatabu H

    更新日期：2006-05-01 00:00:00

  • Cause of satisfaction of search effects in contrast studies of the abdomen.

    abstract：RATIONALE AND OBJECTIVES:Extraintestinal abnormalities visible without contrast material on abdominal radiographs are reported less frequently when contrast examinations are performed. Gaze dwell time was used to determine whether this difference is due to failure by observers to scan plain-film regions of contrast stu...

    journal_title：Academic radiology

    pub_type： 杂志文章

    doi：10.1016/s1076-6332(96)80271-6

    authors： Berbaum KS,Franken EA Jr,Dorfman DD,Miller EM,Krupinski EA,Kreinbring K,Caldwell RT,Lu CH

    更新日期：1996-10-01 00:00:00

  • Optimal ECG trigger point in electron-beam CT studies: three methods for minimizing motion artifacts.

    abstract：RATIONALE AND OBJECTIVES:The authors hypothesized that electrocardiographic triggering near end systole could minimize motion artifacts in electron-beam computed tomography (CT) of the coronary artery. MATERIALS AND METHODS:The study included 2,660 patients who underwent coronary artery calcium scanning with electron-...

    journal_title：Academic radiology

    pub_type： 杂志文章

    doi：10.1016/S1076-6332(03)80722-5

    authors： Mao S,Budoff MJ,Bin L,Liu SC

    更新日期：2001-11-01 00:00:00

  • Rates of disagreement in imaging interpretation in a group of community hospitals.

    abstract：RATIONALE AND OBJECTIVES:Prospective studies of radiologists' interpretations of selected radiographs reported 20-40 years ago indicated error rates of 30% and higher. The authors retrospectively evaluated the interpretations of groups of radiologists and determined a range of rates of disagreement in interpretation. Q...

    journal_title：Academic radiology

    pub_type： 杂志文章

    doi：10.1016/s1076-6332(98)80277-8

    authors： Siegle RL,Baram EM,Reuter SR,Clarke EA,Lancaster JL,McMahan CA

    更新日期：1998-03-01 00:00:00

  • Reliability of MR Quantification of Rotator Cuff Muscle Fatty Degeneration Using a 2-point Dixon Technique in Comparison with the Goutallier Classification: Validation Study by Multiple Readers.

    abstract：RATIONALE AND OBJECTIVES:Presurgical assessment of fatty degeneration is important in the management of patients with rotator cuff tears. The Goutallier classification is widely accepted as a qualitative scoring system, although it is highly observer-dependent and has poor reproducibility. The objective of this study w...

    journal_title：Academic radiology

    pub_type： 杂志文章

    doi：10.1016/j.acra.2017.03.026

    authors： Horiuchi S,Nozaki T,Tasaki A,Yamakawa A,Kaneko Y,Hara T,Yoshioka H

    更新日期：2017-11-01 00:00:00

  • Quality of communication: different patterns of reporting the location of the tip of a nasogastric tube.

    abstract：PURPOSE:This investigation is part of a prospective National Institutes of Health-funded study evaluating three different methods for estimating the optimal length for placement of a new nasogastric (NG) tube. Abdomen radiographs were required to determine the location of the tube tip. Our objective was to analyze diff...

    journal_title：Academic radiology

    pub_type： 杂志文章

    doi：10.1016/j.acra.2012.02.007

    authors： Cohen MD,Ellett M

    更新日期：2012-06-01 00:00:00

  • Simulation of mammographic lesions.

    abstract：RATIONALE AND OBJECTIVES:This study presents a method for generating breast masses and microcalcifications in mammography via simulation. This simulation method allows for the creation of large image datasets with particular lesions, which may serve as a useful tool for perception studies measuring imaging system perfo...

    journal_title：Academic radiology

    pub_type： 杂志文章

    doi：10.1016/j.acra.2006.03.015

    authors： Saunders R,Samei E,Baker J,Delong D

    更新日期：2006-07-01 00:00:00

  • 68Ga-PSMA PET/CT in Patients with Rising Prostatic-Specific Antigen After Definitive Treatment of Prostate Cancer: Detection Efficacy and Diagnostic accuracy.

    abstract：RATIONALE AND OBJECTIVES:68Ga-prostate-specific membrane antigen-11 (68Ga-PSMA-11) is a recently developed positron emission tomography (PET) tracer that can detect prostate cancer (PC) relapses and metastases with high contrast resolution. The aim of this study was to assess the detection efficacy and diagnostic accur...

    journal_title：Academic radiology

    pub_type： 杂志文章

    doi：10.1016/j.acra.2018.05.020

    authors： Hamed MAG,Basha MAA,Ahmed H,Obaya AA,Afifi AHM,Abdelbary EH

    更新日期：2019-04-01 00:00:00

  • Mesoscopic fluorescence tomography of a photosensitizer (HPPH) 3D biodistribution in skin cancer.

    abstract：RATIONALE AND OBJECTIVES:Photodynamic therapy (PDT) is a promising strategy for treating cancer. PDT involves three components: a photosensitizer (PS) drug, a specific wavelength of drug-activating light, and oxygen. A challenge in PDT is the unknown biodistribution of the PS in the target tissue. In this preliminary s...

    journal_title：Academic radiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.acra.2013.11.009

    authors： Ozturk MS,Rohrbach D,Sunar U,Intes X

    更新日期：2014-02-01 00:00:00

  • How to successfully implement E-learning for both students and teachers.

    abstract：RATIONALE AND OBJECTIVES:Electronic learning (e-learning) may provide a means to enhance learning efficacy. However, introduction of e-learning often fails. We describe a strategy of how an e-learning curriculum was successfully implemented. MATERIALS AND METHODS:The curriculum was designed based on published evidence...

    journal_title：Academic radiology

    pub_type： 杂志文章

    doi：10.1016/j.acra.2005.12.006

    authors： Gotthardt M,Siegert MJ,Schlieck A,Schneider S,Kohnert A,Gross MW,Schäfer C,Wagner R,Hörmann S,Behr TM,Engenhart-Cabillic R,Klose KJ,Jungclas H,Glowalla U

    更新日期：2006-03-01 00:00:00

  • Use of Spreadsheets for Research Data Collection and Preparation: A Primer.

    abstract：:Successful research results from the combination of multiple elements, including an appropriate research question, study design, research method, statistical analysis, and interpretation of results. One element of research that is easy to overlook is proper data collection and preparation for analysis. If data collect...

    journal_title：Academic radiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.acra.2015.08.024

    authors： Juluru K,Eng J

    更新日期：2015-12-01 00:00:00

  • Intraluminal air within an obstructed appendix: a CT sign of perforated or necrotic appendicitis.

    abstract：RATIONALE AND OBJECTIVES:The aim of this study was to evaluate the predictive value of intraluminal air for appendiceal necrosis and/or perforation when not apparent on imaging. Additional factors of intraluminal appendicoliths, age, and gender were also assessed. MATERIALS AND METHODS:Patients with pathologically pro...

    journal_title：Academic radiology

    pub_type： 杂志文章

    doi：10.1016/j.acra.2012.04.018

    authors： Azok JT,Kim DH,Munoz Del Rio A,Sonavane SK,Bhalla S,Anaya-Baez V,Menias CO

    更新日期：2012-10-01 00:00:00

  • Design considerations for using PET as a response measure in single site and multicenter clinical trials.

    abstract：RATIONALE AND OBJECTIVES:Positron emission tomography (PET) is used to evaluate response to therapy with increasing interest in having PET provide endpoints for clinical trials. Here we demonstrate impacts of PET measurement error and choice of quantification method on clinical trial design. MATERIALS AND METHODS:Samp...

    journal_title：Academic radiology

    pub_type： 杂志文章

    doi：10.1016/j.acra.2011.10.008

    authors： Doot RK,Kurland BF,Kinahan PE,Mankoff DA

    更新日期：2012-02-01 00:00:00

  • Imaging evidence for renomegaly in patients with POEMS syndrome.

    abstract：RATIONALE AND OBJECTIVES:Organomegaly in POEMS syndrome generally refers to the liver, spleen, and lymph nodes. This study investigates whether there is a significant difference in kidney sizes in patients with POEMS compared to normal controls. MATERIALS AND METHODS:Calculated kidney volumes from 77 patients with POE...

    journal_title：Academic radiology

    pub_type： 历史文章,杂志文章

    doi：10.1016/j.acra.2011.05.008

    authors： Clapp AJ,Lee CU,Wood-Wentz CM,Leung N,Dispenzieri A

    更新日期：2011-10-01 00:00:00

  • Usefulness of 1H MR spectroscopy in the evaluation of myocardial metabolism in patients with dilated idiopathic cardiomyopathy: pilot study.

    abstract：RATIONALE AND OBJECTIVES:Primary dilated cardiomyopathy is a disease of unknown etiology, and it leads to severe heart failure. Abnormalities of the cardiac metabolism can play an important role in prognosis and influence the symptomatology in this group. The aim of this study was to assess cardiac metabolism using pro...

    journal_title：Academic radiology

    pub_type： 杂志文章

    doi：10.1016/s1076-6332(03)00104-1

    authors： Walecki J,Michalak MJ,Michalak E,Bilinska ZT,Ruzyllo W

    更新日期：2003-10-01 00:00:00

  • Establishing a normative atlas of the human lung: computing the average transformation and atlas construction.

    abstract：RATIONALE AND OBJECTIVES:To establish the range of normal for quantitative computed tomography (CT)-based measures of lung structure and function, we seek to develop methods for matching pulmonary structures across individuals and establishing a normative human lung atlas. MATERIALS AND METHODS:In our previous work, w...

    journal_title：Academic radiology

    pub_type： 杂志文章

    doi：10.1016/j.acra.2012.04.025

    authors： Li B,Christensen GE,Hoffman EA,McLennan G,Reinhardt JM

    更新日期：2012-11-01 00:00:00

  • Evaluation of the effect of computer-aided classification of benign and malignant lesions on reader performance in automated three-dimensional breast ultrasound.

    abstract：RATIONALE AND OBJECTIVES:To investigate the effect of a newly developed computer-aided diagnosis (CAD) system on reader interpretation of breast lesions in automated three-dimensional (3D) breast ultrasound. MATERIALS AND METHODS:A CAD system was developed to differentiate malignant lesions from benign lesions includi...

    journal_title：Academic radiology

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.acra.2013.07.013

    authors： Tan T,Platel B,Twellmann T,van Schie G,Mus R,Grivegnée A,Mann RM,Karssemeijer N

    更新日期：2013-11-01 00:00:00

  • Iohexol: effects on uptake of radioactive iodine in the thyroid and on thyroid function.

    abstract：RATIONALE AND OBJECTIVES:The authors attempted to determine whether the use of nonionic contrast media causes uptake of iodine by the thyroid to be blocked and whether use of these agents could cause iodine-induced hyperthyroidism. MATERIALS AND METHODS:Twenty-eight persons, including 22 with thyroid disease, were inc...

    journal_title：Academic radiology

    pub_type： 杂志文章

    doi：10.1016/s1076-6332(98)80026-3

    authors： Nygaard B,Nygaard T,Jensen LI,Court-Payen M,Søe-Jensen P,Nielsen KG,Fugl M,Hansen JM

    更新日期：1998-06-01 00:00:00

  • Asymmetry analysis in rodent cerebral ischemia models.

    abstract：RATIONALE AND OBJECTIVES:An automated method for identification and segmentation of acute/subacute ischemic stroke, using the inherent bi-fold symmetry in brain images, is presented. An accurate and automated method for localization of acute ischemic stroke could provide physicians with a mechanism for early detection ...

    journal_title：Academic radiology

    pub_type： 杂志文章

    doi：10.1016/j.acra.2008.03.013

    authors： Liu SX,Imielinska C,Laine A,Millar WS,Connolly ES,D'Ambrosio AL

    更新日期：2008-09-01 00:00:00

  • Morphologic relationship among the corpus callosum, fornix, anterior commissure, and posterior commissure MRI-based variability study.

    abstract：RATIONALE AND OBJECTIVES:This study explores morphological relationships and structural variability of the corpus callosum (CC), fornix (Fo), anterior (AC), and posterior commissures (PC). MATERIALS AND METHODS:These structures are extracted automatically on the midsagittal plane. The CC and Fo are modeled using best-...

    journal_title：Academic radiology

    pub_type： 杂志文章

    doi：10.1016/j.acra.2005.06.018

    authors： Prakash KN,Nowinski WL

    更新日期：2006-01-01 00:00:00

  • Pulmonary functional magnetic resonance imaging: asthma temporal-spatial maps.

    abstract：RATIONALE AND OBJECTIVES:Hyperpolarized (3)He magnetic resonance imaging (MRI) previously revealed the temporal and spatial heterogeneity of ventilation defects in asthmatics, but these findings have not been used in treatment studies or to guide personalized therapy. Our objective was to exploit the temporal and spati...

    journal_title：Academic radiology

    pub_type： 杂志文章

    doi：10.1016/j.acra.2014.08.002

    authors： Svenningsen S,Guo F,Kirby M,Choy S,Wheatley A,McCormack DG,Parraga G

    更新日期：2014-11-01 00:00:00

  • Accuracy of Cyst Versus Solid Diagnosis in the Breast Using Quantitative Transmission (QT) Ultrasound.

    abstract：RATIONAL AND OBJECTIVES:This study aims to evaluate the diagnostic utility of breast imaging using transmission ultrasound. We present readers' accuracy in determining whether a breast lesion is a cyst versus a solid using transmission ultrasound as an adjunct to mammography. MATERIALS AND METHODS:This retrospective m...

    journal_title：Academic radiology

    pub_type： 杂志文章

    doi：10.1016/j.acra.2017.03.024

    authors： Iuanow E,Smith K,Obuchowski NA,Bullen J,Klock JC

    更新日期：2017-09-01 00:00:00