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Imaging Hepatocellular Carcinoma with Dynamic CT Before and After Transarterial Chemoembolization: Optimal Scan Timing of Arterial Phase.

Abstract：

RATIONALE AND OBJECTIVES:The aim of this study was to determine the optimal arterial phase delay for computed tomography imaging of hepatocellular carcinoma (HCC) before and after transarterial chemoembolization (TACE) using a low iodine dose protocol. MATERIALS AND METHODS:A total of 39 patients with known HCC were imaged with dynamic computed tomography of the liver (40-second scan duration, 60 mL of contrast medium), both on the same day before TACE and 1 day after TACE. Time attenuation curves of vessels, nonmalignant liver parenchyma, and 62 HCCs were normalized to a uniform aortic contrast arrival and analyzed. RESULTS:Maximal arterial phase HCC to liver contrast was reached between 13 and 17 seconds after aortic contrast arrival, both before and after TACE. CONCLUSIONS:Using our low iodine dose protocol, arterial phase imaging of HCC should be performed between 13 and 17 seconds after aortic contrast arrival, both before and after TACE.

journal_name

Acad Radiol

journal_title

Academic radiology

authors

Saake M,Lell MM,Eller A,Wuest W,Heinz M,Uder M,Schmid A

doi

10.1016/j.acra.2015.08.021

subject

Has Abstract

pub_date

2015-12-01 00:00:00

pages

1516-21

issue

12

eissn

1076-6332

issn

1878-4046

pii

S1076-6332(15)00369-4

journal_volume

22

pub_type

杂志文章

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