Abstract:
:Reciprocal translocations pose a serious problem in pig breeding due to the reduced fertility of the carriers. This paper presents a new reciprocal translocation in a phenotypically normal, but hypoprolific (20% reduction) boar. Chromosome banding as well as the FISH technique with the use of BAC and telomeric probes was applied for a detailed characterization of this chromosome rearrangement. The karyotype of the studied boar was described as 38,XY,t(6;16)(p13;q23). The meiotic segregation of the quadrivalent was studied in 1,071 sperms by multicolor FISH. The most frequent segregation patterns were alternate (47.5%) and adjacent 1 (41.9%), while adjacent 2 and 3:1 were less frequent at 1.2 and 9.2%, respectively. Surprisingly, the frequency of the adjacent-1 segregation appeared to be relatively high, when compared with human and pig reciprocal translocations studied by sperm FISH. Our study, along with a review of the literature, shows that a reduction of fertility in the carriers and the incidence of different segregation patterns of the quadrivalent may vary within a broad range, and both aspects seem to be unrelated. A need for obligatory karyotype screening programs of artificial insemination boars is emphasized.
journal_name
Cytogenet Genome Resjournal_title
Cytogenetic and genome researchauthors
Kociucka B,Szczerbal I,Bugaj S,Orsztynowicz M,Switonski Mdoi
10.1159/000355213subject
Has Abstractpub_date
2014-01-01 00:00:00pages
21-7issue
1eissn
1424-8581issn
1424-859Xpii
000355213journal_volume
142pub_type
杂志文章abstract::Coamplification of multiple segments of chromosome 2, including an MYCN-bearing segment, was examined in 2 cancer cell lines, NCI-H69 (lung cancer) and IMR-32 (neuroblastoma). High-resolution array-CGH analysis revealed 13 and 6 highly amplified segments located at different sites in chromosome 2 in NCI-H69 and IMR-32...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000334349
更新日期:2012-01-01 00:00:00
abstract::The ChickRH6 radiation hybrid panel has been used to construct consensus chromosome radiation hybrid (RH) maps of the chicken genome. Markers genotyped were either from throughout the genome or targeted to specific chromosomes and a large proportion (one third) of data was the result of collaborative efforts. Altogeth...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000103160
更新日期:2007-01-01 00:00:00
abstract::In birds, females are heterogametic (ZW), while males are homogametic (ZZ). It has been proposed that there is no dosage compensation for the expression of Z-linked genes in birds. In order to examine if the genes are inactivated on one of the two Z chromosomes, we analyzed the allelic expression of the B4GALT1 and CH...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000071609
更新日期:2002-01-01 00:00:00
abstract::The Mx gene was originally found in laboratory mice in an infection experiment using influenza virus (Lindermann, 1962). Almost all of the mouse strains in that experiment died from the infection, and only the A2G strain had resistance to the virus. This resistant character was shown to be inherited as a single autoso...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000103200
更新日期:2007-01-01 00:00:00
abstract::Fat accumulation is a polygenic trait which has a significant impact on human health and animal production. Obesity is also an increasingly serious problem in dog breeding. The FTO and INSIG2 are considered as candidate genes associated with predisposition for human obesity. In this report we present a comparative gen...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000330457
更新日期:2011-01-01 00:00:00
abstract::The X chromosomes of the extant equids, in general, share morphology and banding pattern similarities. However, the donkey X is, in part, an exception because of significantly different centromeric index and variant banding patterns in the pericentromeric region. To verify the underlying molecular basis of this differ...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000063050
更新日期:2002-01-01 00:00:00
abstract::There is incredible morphological and behavioral diversity among the hundreds of breeds of the domestic dog, CANIS FAMILIARIS. Many of these breeds have come into existence within the last few hundred years. While there are obvious phenotypic differences among breeds, there is marked interbreed genetic homogeneity. Th...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章,评审
doi:10.1159/000075756
更新日期:2003-01-01 00:00:00
abstract::RNA-binding proteins are involved in post-transcriptional processes like mRNA stabilization, post-transcriptional modification, and transport and have been suggested to play an important role in developmental gene regulation. We report here the cloning and characterization of Brunol4, a novel mouse cDNA closely relate...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000066619
更新日期:2002-01-01 00:00:00
abstract::Early, rapid and reliable diagnosis is of first priority in prenatal medicine. The combination of specific sonographic markers (e.g. nuchal translucency) and biochemical parameters in maternal serum (e.g. free beta-human chorionic gonadotropin, pregnancy-associated plasma protein A), has already dramatically improved ...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000094217
更新日期:2006-01-01 00:00:00
abstract::High density livestock to human comparative maps are necessary for the implementation of comparative positional candidate gene cloning. We have constructed a high-density comparative radiation hybrid (RH) map of the telomeric end of bovine chromosome 2 (BTA2) using a 12,000-rad whole genome cattle-hamster radiation hy...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000076295
更新日期:2003-01-01 00:00:00
abstract::Among birds, species with the ZZ/ZW sex determination system generally show significant differences in morphology and size between the Z and W chromosomes (with the W usually being smaller than the Z). In the present study, we report for the first time the karyotype of the spot-flanked gallinule (Gallinula melanops) b...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000501381
更新日期:2019-01-01 00:00:00
abstract::Neacomys (Sigmodontinae) comprises 8 species mainly found in the Amazonian region. We describe 5 new karyotypes from Brazilian Amazonia: 2 cytotypes for N. paracou (2n = 56/FNa = 62-66), 1 for N. dubosti (2n = 64/FNa = 68), and 2 for Neacomys sp. (2n = 58/FNa = 64-70), with differences in the 18S rDNA. Telomeric probe...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000441173
更新日期:2015-01-01 00:00:00
abstract::We have tested the influence of recombinantly-elongated chromosome arms on nuclear divisions in barley and confirmed a rule according to which half the length of the average spindle axis defines the upper tolerance limit for chromosome arm length. A slightly longer chromosome arm caused incomplete separation of sister...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000068530
更新日期:2002-01-01 00:00:00
abstract::In 1957/58 the British Government conducted a series of nuclear tests in the mid-Pacific codenamed Operation Grapple, which involved several naval vessels from Britain and New Zealand. Two New Zealand frigates with 551 personnel onboard were stationed at various distances between 20 and 150 nautical miles from ground ...
journal_title:Cytogenetic and genome research
pub_type: 历史文章,杂志文章
doi:10.1159/000125832
更新日期:2008-01-01 00:00:00
abstract::The aim of this review is to describe the level of intimacy between Ty retrotransposons (Ty1-Ty5) and their host the yeast Saccharomyces cerevisiae. The effects of Ty location in the genome and of host proteins on the expression and mobility of Ty elements are highlighted. After a brief overview of Ty diversity and ev...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章,评审
doi:10.1159/000084940
更新日期:2005-01-01 00:00:00
abstract::Spinocerebellar ataxia type 12 (SCA12), now described in European-American and Asian (Indian) pedigrees, is unique among the SCAs from clinical, pathological, and molecular perspectives. Clinically, the distinguishing feature is early and prominent action tremor with variability in other signs. Pathologically, brain M...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章,评审
doi:10.1159/000072854
更新日期:2003-01-01 00:00:00
abstract::A physical chromosome mapping of the H1 histone and 5S and 18S ribosomal RNA (rRNA) genes was performed in interspecific hybrids of Pseudoplatystoma corruscans and P. reticulatum. The results showed that 5S rRNA clusters were located in the terminal region of 2 chromosomes. H1 histone and 18S ribosomal genes were co-l...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000345299
更新日期:2013-01-01 00:00:00
abstract::Since the discovery of SRY/SRY as a testis-determining gene on the mammalian Y chromosome in 1990, extensive studies have been carried out on the immediate target of SRY/SRY and genes functioning in the course of testis development. Comparative studies in non-mammalian vertebrates including birds have failed to find a...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章,评审
doi:10.1159/000071599
更新日期:2002-01-01 00:00:00
abstract::In the zebra finch, 2 alternative morphs regarding centromere position were described for chromosome 6. This polymorphism was interpreted to be the result of a pericentric inversion, but other causes of the centromere repositioning were not ruled out. We used immunofluorescence localization to examine the distribution...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000442656
更新日期:2015-01-01 00:00:00
abstract::Chromosome microdeletions or duplications are detected in 10-20% of patients with mental impairment and normal karyotypes. A few cases have been reported of mental impairment with microdeletions comprising tumor suppressor genes. By array-CGH we detected 4 mentally impaired individuals carrying de novo microdeletions ...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000218743
更新日期:2009-01-01 00:00:00
abstract::The epigenome is thought to mediate between genes and the environment, particularly in response to adverse life experiences. Similar to other psychiatric diseases, the suicide liability of an individual appears to be influenced by many genetic factors of small effect size as well as by environmental stressors. To iden...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000435778
更新日期:2015-01-01 00:00:00
abstract::We analyzed repeat sequences composition in the genome of cucumber inbred line 9930 using whole-genome shotgun reads. The analysis showed that satellite DNA sequences are the most dominant components in the cucumber genome. The distribution pattern of several tandem repeat sequences (Type I/II, Type III and Type IV) o...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000151320
更新日期:2008-01-01 00:00:00
abstract::We report the first case of an 18p11.32 deletion, detected by array CGH, associated with a drug-resistant form of atypical absence epilepsy, global developmental delay and no signs of holoprosencephaly (HPE). In particular, this region encompasses 19 genes, and none of these genes have been strictly associated with ep...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000438502
更新日期:2015-01-01 00:00:00
abstract::The lizard genus Gekko consists of over 30 species distributed in Asia and Oceania. From the insular region of East Asia including Japan and Taiwan, 9 species (G. hokouensis, G. japonicus, G. shibatai, G. tawaensis, G. vertebralis,G. yakuensis, and 3 undescribed species) are currently recognized. We made karyological ...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000303334
更新日期:2009-01-01 00:00:00
abstract::Holoprosencephaly (HPE) is the most common congenital malformation of the brain and face in humans. In this study we report the analysis of SIL (Sumacr;CL iumacr;nterrupting lumacr;ocus) as a candidate gene for HPE. Fluorescent in situ hybridization (FISH) analysis using a BAC 246e16 confirmed the assignment of SIL to...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000064057
更新日期:2002-01-01 00:00:00
abstract::The Hodgkin cell line U-HO1 was established from a malignant pleural effusion of a 23-year-old male patient during the end stage of refractory nodular sclerosing classical Hodgkin lymphoma (cHL). Since its establishment in 2005, U-HO1 has maintained stable characteristics in vitro and has a doubling time of about 4 da...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000112062
更新日期:2007-01-01 00:00:00
abstract::Proximal 6q deletions have a milder phenotype than middle and distal 6q deletions. We describe 2 patients with non-overlapping deletions of about 15 and 19 Mb, respectively, which subdivide the proximal 6q region into 2 parts. The aberrations were identified using karyotyping and analysed using mBAND and array CGH. Th...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000334709
更新日期:2012-01-01 00:00:00
abstract::In Europe, 2 different diploid chromosome numbers, 2n = 54 and 2n = 56, have been described in the lesser horseshoe bat (Rhinolophushipposideros). The eastern form with 2n = 56 extends from the Czech Republic to Greece. To date, specimens with 54 chromosomes have been reported only from Spain and Germany. This study e...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000447111
更新日期:2016-01-01 00:00:00
abstract::Transposable elements are disproportionately abundant in the heterochromatin of Drosophila melanogaster. Among the forces contributing to this bias in genomic distribution, fixation due to positive selection has been put forward. We have studied I-related elements which are located in pericentromeric heterochromatin a...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000084950
更新日期:2005-01-01 00:00:00
abstract::Sex-determining mechanisms (SDMs) set an individual's sexual fate by its genotype (genotypic sex determination, GSD) or environmental factors like temperature (temperature- dependent sex determination, TSD), as in turtles where the GSD "trigger" remains unknown. SDMs co-evolve with turtle chromosome number, perhaps be...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000497302
更新日期:2019-01-01 00:00:00