Abstract:
:Since the discovery of SRY/SRY as a testis-determining gene on the mammalian Y chromosome in 1990, extensive studies have been carried out on the immediate target of SRY/SRY and genes functioning in the course of testis development. Comparative studies in non-mammalian vertebrates including birds have failed to find a gene equivalent to SRY/SRY, whereas they have suggested that most of the downstream factors found in mammals including SOX9 are also involved in the process of gonadal differentiation. Although a gene whose function is to trigger the cascade of gene expression toward gonadal differentiation has not been identified yet on either W or Z chromosomes of birds, a few interesting genes have been found recently on the sex chromosomes of chickens and their possible roles in sex determination or sex differentiation are being investigated. It is the purpose of this review to summarize the present knowledge of these sex chromosome-linked genes in chickens and to give perspectives and point out questions concerning the mechanisms of avian sex determination.
journal_name
Cytogenet Genome Resjournal_title
Cytogenetic and genome researchauthors
Mizuno S,Kunita R,Nakabayashi O,Kuroda Y,Arai N,Harata M,Ogawa A,Itoh Y,Teranishi M,Hori Tdoi
10.1159/000071599keywords:
subject
Has Abstractpub_date
2002-01-01 00:00:00pages
236-44issue
1-4eissn
1424-8581issn
1424-859Xpii
71599journal_volume
99pub_type
杂志文章,评审abstract::The osprey (Pandion haliaetus) has a diploid number of 74 chromosomes, consisting of a large number of medium-sized macrochromosomes and relatively few microchromosomes; this differs greatly from the typical avian karyotype. Chromosome painting with chicken DNA probes revealed that the karyotype of P. haliaetus differ...
journal_title:Cytogenetic and genome research
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abstract::Most human cancers are characterized by genomic instability. Changes associated with such may result in altered expression of numerous genes. The sequence information available in the public databases can be used to identify transcripts differentially expressed in cancers. Determining cancer-related genes that are com...
journal_title:Cytogenetic and genome research
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journal_title:Cytogenetic and genome research
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journal_title:Cytogenetic and genome research
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journal_title:Cytogenetic and genome research
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journal_title:Cytogenetic and genome research
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journal_title:Cytogenetic and genome research
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journal_title:Cytogenetic and genome research
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journal_title:Cytogenetic and genome research
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journal_title:Cytogenetic and genome research
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journal_title:Cytogenetic and genome research
pub_type: 杂志文章,评审
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更新日期:2004-01-01 00:00:00
abstract::The aim of this review is to describe the level of intimacy between Ty retrotransposons (Ty1-Ty5) and their host the yeast Saccharomyces cerevisiae. The effects of Ty location in the genome and of host proteins on the expression and mobility of Ty elements are highlighted. After a brief overview of Ty diversity and ev...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章,评审
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更新日期:2005-01-01 00:00:00
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journal_title:Cytogenetic and genome research
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doi:10.1159/000227831
更新日期:2009-01-01 00:00:00
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journal_title:Cytogenetic and genome research
pub_type: 杂志文章,评审
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更新日期:2010-07-01 00:00:00
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journal_title:Cytogenetic and genome research
pub_type: 杂志文章,评审
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journal_title:Cytogenetic and genome research
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doi:10.1159/000298794
更新日期:2010-01-01 00:00:00
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journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000365232
更新日期:2014-01-01 00:00:00
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journal_title:Cytogenetic and genome research
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journal_title:Cytogenetic and genome research
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journal_title:Cytogenetic and genome research
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journal_title:Cytogenetic and genome research
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journal_title:Cytogenetic and genome research
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更新日期:2005-01-01 00:00:00
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journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000325744
更新日期:2011-01-01 00:00:00
abstract::Chromosome microdeletions or duplications are detected in 10-20% of patients with mental impairment and normal karyotypes. A few cases have been reported of mental impairment with microdeletions comprising tumor suppressor genes. By array-CGH we detected 4 mentally impaired individuals carrying de novo microdeletions ...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000218743
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journal_title:Cytogenetic and genome research
pub_type: 杂志文章
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更新日期:2005-01-01 00:00:00
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journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000095229
更新日期:2006-01-01 00:00:00
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journal_title:Cytogenetic and genome research
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journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000430764
更新日期:2015-01-01 00:00:00
abstract::The most prevalent structural variations in the human genome are copy number variations (CNVs), which appear predominantly in the subtelomeric regions. Variable sizes of 4p/4q CNVs have been associated with several different psychiatric findings and developmental disability (DD). We analyzed 105 patients with congenit...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000448905
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