Abstract:
:The T2 family of miniature inverted-repeat transposable elements (T2-MITE) is a prevalent MITE family found in both Xenopus(Silurana) tropicalis and X. laevis. Some subfamilies, particularly T2-A1 and T2-C, may have originated prior to the diversification of the 2 Xenopus lineages and currently include active members in X. tropicalis, whereas another subfamily, T2-E, may have lost its transposition activity even earlier. The distribution of each T2-MITE subfamily in X. tropicalis was investigated and compared to evaluate the evolutionary dynamics of the T2-MITE subfamilies. The subfamilies showed differences in chromosomal distribution, uniformity of insertion density on scaffolds, ratios of upstream to downstream insertions with respect to genes, and their distance from genes. Among these, the T2-C subfamily was interesting because it was frequently inserted upstream and close to genes and because genes with close insertions of this subfamily showed high correlations in spatial expression patterns. This unique distribution and long-lived transposition activity may reflect a mutual relationship evolved between this subfamily and the host.
journal_name
Cytogenet Genome Resjournal_title
Cytogenetic and genome researchauthors
Hikosaka A,Uno Y,Matsuda Ydoi
10.1159/000430764subject
Has Abstractpub_date
2015-01-01 00:00:00pages
230-42issue
3-4eissn
1424-8581issn
1424-859Xpii
000430764journal_volume
145pub_type
杂志文章abstract::The genus Astyanax is a specious Neotropical fish group, occurring from the south area of the United States to Argentina. During the past few years, intensive studies on representatives of this group have been performed, broadening the genetic, taxonomic and biogeographical knowledge considerably. However, phylogeneti...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000354885
更新日期:2013-01-01 00:00:00
abstract::We review our progress using genomics approaches to examine key antiviral defenses of the White Pekin mallard duck, Anas platyrhynchos. Our interest stems from the fact that ducks are the natural host of avian influenza, and are an important animal model for hepatitis B research. First, we have conducted an expressed ...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章,评审
doi:10.1159/000103180
更新日期:2007-01-01 00:00:00
abstract::RNA-binding proteins are involved in post-transcriptional processes like mRNA stabilization, post-transcriptional modification, and transport and have been suggested to play an important role in developmental gene regulation. We report here the cloning and characterization of Brunol4, a novel mouse cDNA closely relate...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000066619
更新日期:2002-01-01 00:00:00
abstract::We analyzed genetic changes in condylomas (four cases), vulvar intraepithelial neoplasia I-III (VIN I-III, eleven cases), and primary vulvar squamous cell carcinomas (VSCC, ten cases) by high-resolution comparative genomic hybridization (HR-CGH) and flowcytometry. All samples were also human papilloma virus (HPV)-geno...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000078559
更新日期:2004-01-01 00:00:00
abstract::For normal transition through meiosis, chromosomes rely on pairing with their homologues. Chromosomes which fail to pair, univalents, behave irregularly and may undergo various types of breakage across their centromeres. Here, we analyzed the meiotic behavior of misdivision products themselves: isochromosomes and telo...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000497301
更新日期:2019-01-01 00:00:00
abstract::Recent studies of the LTR-retrotransposons of Schizosaccharomyces pombe have shed considerable light on their evolution and function. The sequencing of the S. pombe genome allowed analysis of its transposon content. This analysis provides information about the maintenance and loss of transposons in the genome. The res...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000084990
更新日期:2005-01-01 00:00:00
abstract::Maternal uniparental disomy (UPD) 15 is one of the molecular causes of Prader-Willi syndrome (PWS), a multisystem disorder which presents with neonatal hypotonia and feeding difficulty. Current diagnostic algorithms differ regarding the use of SNP microarray to detect PWS. We retrospectively examined the frequency wit...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000478921
更新日期:2017-01-01 00:00:00
abstract::Based on the analysis of 20 different monocot and eudicot species, we propose that the centromeric distribution of the phosphorylated histone H2AThr120 is evolutionary highly conserved across species with mono- and holocentric chromosomes. Therefore, antibodies recognizing the phosphorylated threonine 120 of the histo...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000360018
更新日期:2014-01-01 00:00:00
abstract::LINE-1 (L1) retrotransposons constitute the dominant category of transposons in mammalian genomes. L1 elements are active in the vast majority of mammals, and only a few cases of L1 extinction have been documented. The only possible case of extinction in primates was suggested for South American spider monkeys. Howeve...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000490481
更新日期:2018-01-01 00:00:00
abstract::We studied the organization of mouse satellite 3 and 4 (MS3 and MS4) in comparison with major (MaSat) and minor (MiSat) DNA sequences, located in the centromeric and pericentromeric regions of mouse telocentric chromosomes by fiber-FISH. The centromeric region consists of a small block of MiSat and MS3 followed by a p...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000089878
更新日期:2006-01-01 00:00:00
abstract::All dogroses (Rosa sect. Caninae) are characterized by the peculiar canina meiosis in which genetic material is unevenly distributed between female and male gametes. The pan-canina rDNA family (termed beta) appears to be conserved in all dogroses analyzed so far. Here, we have studied rDNAs in experimental hybrids obt...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000360437
更新日期:2014-01-01 00:00:00
abstract::The Hodgkin cell line U-HO1 was established from a malignant pleural effusion of a 23-year-old male patient during the end stage of refractory nodular sclerosing classical Hodgkin lymphoma (cHL). Since its establishment in 2005, U-HO1 has maintained stable characteristics in vitro and has a doubling time of about 4 da...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000112062
更新日期:2007-01-01 00:00:00
abstract::Huntington's disease (HD) is a genetically dominant neurodegenerative condition caused by an unique mutation in the disease gene huntingtin. Although the Huntington protein (Htt) is ubiquitously expressed, expansion of the polyglutamine tract in Htt leads to the progressive loss of specific neuronal subpopulations in ...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章,评审
doi:10.1159/000072864
更新日期:2003-01-01 00:00:00
abstract::In an attempt to analyze the organization of repetitive DNAs in the amphibian genome, 7 microsatellite motifs and a 5S rDNA sequence were synthesized and mapped in the karyotypes of 5 Amolops species. The results revealed nonrandom distribution of the microsatellite repeats, usually in the heterochromatic regions, as ...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000499416
更新日期:2019-01-01 00:00:00
abstract::The ChickRH6 radiation hybrid panel has been used to construct consensus chromosome radiation hybrid (RH) maps of the chicken genome. Markers genotyped were either from throughout the genome or targeted to specific chromosomes and a large proportion (one third) of data was the result of collaborative efforts. Altogeth...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000103160
更新日期:2007-01-01 00:00:00
abstract::The DDX4/VASA gene plays an important role in germ cell development in animals. We cloned and characterized a marsupial DDX4/VASA homolog (TvDDX4, 2,769 bps) from the possum and examined its expression in adult tissues at mRNA and protein levels. The isolated cDNA had a deduced 704 amino acid residues with significant...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000266170
更新日期:2009-01-01 00:00:00
abstract::Radiation-induced chromosome damage can be measured in interphase using the Premature Chromosome Condensation (PCC) technique. With the introduction of a new PCC technique using the potent phosphatase inhibitor calyculin-A, chromosomes can be condensed within five minutes, and it is now possible to examine the early d...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章,评审
doi:10.1159/000077491
更新日期:2004-01-01 00:00:00
abstract::Economically important traits such as growth and backfat in pigs have been shown to be influenced by genes in swine chromosome (SSC) 10q12-->qter corresponding to human chromosome (HSA) 10p. However, since gene information in the swine chromosomal region was limited, we attempted to generate a dense comparative map be...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000087523
更新日期:2006-01-01 00:00:00
abstract::The human male specific expressed gene families CDY and DAZ are known to be repetitively clustered in the Y-specific region of the human Y chromosome. Comparative FISH-mapping of DNA clones specific for CDY and DAZ resulted in a Y-specific but diverse signal pattern within the non-recombining region of the Y-chromosom...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000063021
更新日期:2002-01-01 00:00:00
abstract::Using FISH and RH mapping a chromosomal map of rat chromosome 10 (RNO10) was constructed. Our mapping data were complemented by other published data and the final map was compared to maps of mouse and human chromosomes. RNO10 contained segments homologous to mouse chromosomes (MMU) 11, 16 and 17, with evolutionary bre...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000063052
更新日期:2002-01-01 00:00:00
abstract::A 17-year-old girl presented with a distinct phenotype mainly featuring craniofacial dysmorphism, including a disproportioned large, round, elongated face; hypertelorism; deep-set eyes with short palpebral fissures; obesity (BMI 37), and a neuropsychiatric disorder with high-functioning autism. Postnatal conventional ...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000481331
更新日期:2017-01-01 00:00:00
abstract::In birds, females are heterogametic (ZW), while males are homogametic (ZZ). It has been proposed that there is no dosage compensation for the expression of Z-linked genes in birds. In order to examine if the genes are inactivated on one of the two Z chromosomes, we analyzed the allelic expression of the B4GALT1 and CH...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000071609
更新日期:2002-01-01 00:00:00
abstract::The X chromosomes of the extant equids, in general, share morphology and banding pattern similarities. However, the donkey X is, in part, an exception because of significantly different centromeric index and variant banding patterns in the pericentromeric region. To verify the underlying molecular basis of this differ...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000063050
更新日期:2002-01-01 00:00:00
abstract::Most human cancers are characterized by genomic instability. Changes associated with such may result in altered expression of numerous genes. The sequence information available in the public databases can be used to identify transcripts differentially expressed in cancers. Determining cancer-related genes that are com...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000087513
更新日期:2006-01-01 00:00:00
abstract::The sense of taste is a chemosensory system responsible for basic food appraisal. Humans distinguish between five primary tastes: bitter, sweet, sour, salty and umami. The molecular events in the perception of bitter taste are believed to start with the binding of specific water-soluble molecules to G-protein-coupled ...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000068546
更新日期:2002-01-01 00:00:00
abstract::Proximal 6q deletions have a milder phenotype than middle and distal 6q deletions. We describe 2 patients with non-overlapping deletions of about 15 and 19 Mb, respectively, which subdivide the proximal 6q region into 2 parts. The aberrations were identified using karyotyping and analysed using mBAND and array CGH. Th...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000334709
更新日期:2012-01-01 00:00:00
abstract::In rye each B chromosome (B) represents 5.5% of the diploid A genome. Rye Bs have several nuclear to whole plant effects although they seem to bear no genes except for the ones that lead to their maintenance within a population. In this context, and considering that rye Bs are enriched in repetitive non-coding regions...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000079306
更新日期:2004-01-01 00:00:00
abstract::Rubus yellow net virus (RYNV) infects Rubus spp., causing a severe decline when present in mixed infections with other viruses. RYNV belongs to the family Caulimoviridae, also known as plant pararetroviruses, which can exist as episomal or integrated elements (endogenous). Most of integrated pararetroviruses are nonin...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000509845
更新日期:2020-01-01 00:00:00
abstract::In the zebra finch, 2 alternative morphs regarding centromere position were described for chromosome 6. This polymorphism was interpreted to be the result of a pericentric inversion, but other causes of the centromere repositioning were not ruled out. We used immunofluorescence localization to examine the distribution...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000442656
更新日期:2015-01-01 00:00:00
abstract::The most prevalent structural variations in the human genome are copy number variations (CNVs), which appear predominantly in the subtelomeric regions. Variable sizes of 4p/4q CNVs have been associated with several different psychiatric findings and developmental disability (DD). We analyzed 105 patients with congenit...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000448905
更新日期:2016-01-01 00:00:00