Abstract:
:We have tested the influence of recombinantly-elongated chromosome arms on nuclear divisions in barley and confirmed a rule according to which half the length of the average spindle axis defines the upper tolerance limit for chromosome arm length. A slightly longer chromosome arm caused incomplete separation of sister chromatids in approximately 70% of mitotic telophase cells and >2.5% of daughter cells showing a micronucleus, due to disruption of non-separated sister chromatids by the newly forming cell wall. In homozygous condition, this elongated chromosome mediated a slower growth and reduced fertility of the carrier plants. Its meiotic transmission was not impaired because of the larger spindle dimensions in meiocytes as compared to those in mitotic cells.
journal_name
Cytogenet Genome Resjournal_title
Cytogenetic and genome researchauthors
Hudakova S,Künzel G,Endo TR,Schubert Idoi
10.1159/000068530keywords:
subject
Has Abstractpub_date
2002-01-01 00:00:00pages
101-7issue
1eissn
1424-8581issn
1424-859Xpii
68530journal_volume
98pub_type
杂志文章abstract::Recent studies of the LTR-retrotransposons of Schizosaccharomyces pombe have shed considerable light on their evolution and function. The sequencing of the S. pombe genome allowed analysis of its transposon content. This analysis provides information about the maintenance and loss of transposons in the genome. The res...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000084990
更新日期:2005-01-01 00:00:00
abstract::Studies of complete genomes are leading to a new understanding of the biology of mammals and providing ongoing insights into the fundamental aspects of the organization and evolution of biological systems. Comparison of primate genomes can identify aspects of their organization, regulation and function that appeared d...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章,评审
doi:10.1159/000080796
更新日期:2005-01-01 00:00:00
abstract::Despite extensive analyses on the centromere and its associated proteins, detailed studies of centromeric DNA structure have provided limited information about its topography in condensed chromatin. We have developed a method with correlative fluorescence light microscopy and atomic force microscopy that investigates ...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000348744
更新日期:2013-01-01 00:00:00
abstract::To study the origin and evolution of naturally occurring polyploids, we performed phylogenetic analyses of nuclear ribosomal DNA spacers combined with molecular cytogenetics in 55 accessions of 27 taxa of the oat genus Helictochloa. A complex pattern of reticulate evolution was revealed with many diploid species and e...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000361002
更新日期:2014-01-01 00:00:00
abstract::An important aspect of genome reprogramming is the establishment and maintenance of gamete-specific DNA methylation patterns that distinguish the parental alleles of imprinted genes. Disrupting the accurate transmission of genomic imprints by interfering with these methylation patterns causes severe defects in fetal g...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章,评审
doi:10.1159/000090822
更新日期:2006-01-01 00:00:00
abstract::Huntington's disease (HD) is a genetically dominant neurodegenerative condition caused by an unique mutation in the disease gene huntingtin. Although the Huntington protein (Htt) is ubiquitously expressed, expansion of the polyglutamine tract in Htt leads to the progressive loss of specific neuronal subpopulations in ...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章,评审
doi:10.1159/000072864
更新日期:2003-01-01 00:00:00
abstract::The Congo African grey parrot (Psittacus erithacus, PER) is an endemic species of Central Africa, valued for its intelligence and listed as vulnerable due to poaching and habitat destruction. Improved knowledge about the P. erithacus genome is needed to address key biological questions and conservation of this species...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000444136
更新日期:2015-01-01 00:00:00
abstract::We analyzed the DNA amount in X and B chromosomes of 2 XX/X0 grasshopper species (Eyprepocnemis plorans and Locusta migratoria), by means of Feulgen image analysis densitometry (FIAD), using previous estimates in L. migratoria as standard (5.89 pg). We first analyzed spermatids of 0B males and found a bimodal distribu...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000324690
更新日期:2011-01-01 00:00:00
abstract::Coamplification of multiple segments of chromosome 2, including an MYCN-bearing segment, was examined in 2 cancer cell lines, NCI-H69 (lung cancer) and IMR-32 (neuroblastoma). High-resolution array-CGH analysis revealed 13 and 6 highly amplified segments located at different sites in chromosome 2 in NCI-H69 and IMR-32...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000334349
更新日期:2012-01-01 00:00:00
abstract::Scanning electron microscopy (SEM) proves to be an appropriate technique for imaging chromatin organization in meiosis I and II of rye (Secale cereale) down to a resolution of a few nanometers. It could be shown for the first time that organization of basic structural elements (coiled and parallel fibers, chromomeres)...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000078021
更新日期:2004-01-01 00:00:00
abstract::Transposable elements are disproportionately abundant in the heterochromatin of Drosophila melanogaster. Among the forces contributing to this bias in genomic distribution, fixation due to positive selection has been put forward. We have studied I-related elements which are located in pericentromeric heterochromatin a...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000084950
更新日期:2005-01-01 00:00:00
abstract::We compiled 104 constitutional de novo or sporadic rearranged chromosomes mimicking recombinants from a parental pericentric inversion in order to comment on their occurrence and parental derivation, meiotic or postzygotic origin, mean parental ages, and underlying pathways. Chromosomes involved were 1-9, 13-18, 20-22...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000351184
更新日期:2013-01-01 00:00:00
abstract::A physical chromosome mapping of the H1 histone and 5S and 18S ribosomal RNA (rRNA) genes was performed in interspecific hybrids of Pseudoplatystoma corruscans and P. reticulatum. The results showed that 5S rRNA clusters were located in the terminal region of 2 chromosomes. H1 histone and 18S ribosomal genes were co-l...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000345299
更新日期:2013-01-01 00:00:00
abstract::Scapinin has been found to bind to cytoplasmic actin and is also a putative regulatory subunit of protein phosphatase-1 (PP1). It is found attached to the nuclear matrix-intermediate filament (NM-IF) and is down-regulated by differentiation of tumor cells. We have analyzed the genomic structure and tissue-specific exp...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000094797
更新日期:2006-01-01 00:00:00
abstract::Genetic strategies for the post-genomic sequence age will be designed to provide information about gene function in a myriad of physiological processes. Here an ENU mutagenesis program (http://reprogenomics.jax.org) is described that is generating a large resource of mutant mouse models of infertility; male and female...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000078192
更新日期:2004-01-01 00:00:00
abstract::Y chromosomal azoospermia factor (AZF) regions AZFa, AZFb and AZFc represent hotspots for copy number variations (CNVs) in the human genome; yet the number of reports of AZFa-linked duplications remains limited. Nonallelic homologous recombination has been proposed as the underlying mechanism of CNVs in AZF regions. I...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000377649
更新日期:2014-01-01 00:00:00
abstract::We review our progress using genomics approaches to examine key antiviral defenses of the White Pekin mallard duck, Anas platyrhynchos. Our interest stems from the fact that ducks are the natural host of avian influenza, and are an important animal model for hepatitis B research. First, we have conducted an expressed ...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章,评审
doi:10.1159/000103180
更新日期:2007-01-01 00:00:00
abstract::2q33 deletions are considered to constitute a distinct clinical entity (Glass syndrome or 2q33 microdeletion syndrome) with a characteristic phenotype. Most patients have moderate to severe developmental delay, speech delay, a particular behavioural phenotype, feeding problems, growth restriction, a typical facial app...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000452090
更新日期:2016-01-01 00:00:00
abstract::The aim of this review is to describe the level of intimacy between Ty retrotransposons (Ty1-Ty5) and their host the yeast Saccharomyces cerevisiae. The effects of Ty location in the genome and of host proteins on the expression and mobility of Ty elements are highlighted. After a brief overview of Ty diversity and ev...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章,评审
doi:10.1159/000084940
更新日期:2005-01-01 00:00:00
abstract::The human brain is distinguished by its remarkable size, high energy consumption, and cognitive abilities compared to all other mammals and non-human primates. However, little is known about what has accelerated brain evolution in the human lineage. One possible explanation is that the appearance of advanced communica...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000335465
更新日期:2012-01-01 00:00:00
abstract::Here, a new satellite-DNA family is isolated and characterized from wedge sole, Dicologoglossa cuneata Moreau, 1881 (Pleuronectiformes), a fish having a small genome. This satellite-DNA family of sequences was isolated by conventional cloning after digestion of genomic DNA with the DraI restriction enzyme. Repeat unit...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000138896
更新日期:2008-01-01 00:00:00
abstract::Twelve weeks after repeated spontaneous mating between a Bentheimer Landschaf ram and a West African dwarf doe was observed, the doe aborted a dead fetus. The aim of this study was to verify the parentage and the species of the supposed parents and the hybrid status of the fetus, using cytogenetic and molecular geneti...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000227841
更新日期:2009-01-01 00:00:00
abstract::The mitotic chromosomes of 4 anuran species were examined by various classical banding techniques and by fluorescence in situ hybridization using a (TTAGGG)n repeat. Large intrachromosomal telomeric sequences (ITSs) were demonstrated in differing numbers and chromosome locations. A detailed comparison of the present r...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000446298
更新日期:2016-01-01 00:00:00
abstract::In 1957/58 the British Government conducted a series of nuclear tests in the mid-Pacific codenamed Operation Grapple, which involved several naval vessels from Britain and New Zealand. Two New Zealand frigates with 551 personnel onboard were stationed at various distances between 20 and 150 nautical miles from ground ...
journal_title:Cytogenetic and genome research
pub_type: 历史文章,杂志文章
doi:10.1159/000125832
更新日期:2008-01-01 00:00:00
abstract::In recent years increasing attention has been paid to the cytogenetic control of Italian Mediterranean river buffalo (BBU) bulls authorized as sires which are registered in the stud book. Chromosome abnormalities described in this species are mainly numerical and affecting sex chromosomes. During routine cytogenetic a...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000342360
更新日期:2013-01-01 00:00:00
abstract::The identification of individual dog chromosomes is problematic because the 38 pairs of autosomes are small and acrocentric. Here we describe the design and application of a FISH tool that enables definitive identification of each dog autosome in a normal karyotype, without relying on subjective interpretation of DAPI...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000098187
更新日期:2007-01-01 00:00:00
abstract::This article presents the first physical mapping carried out in the Senegalese sole (Solea senegalensis), an important marine fish species of Southern Europe. Eight probes were designated to pick up genes of interest in aquaculture (candidate genes) from a bacterial artificial chromosome (BAC) library using a method o...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000355001
更新日期:2013-01-01 00:00:00
abstract::We previously revealed similarity in gene expression patterns between human brain and testis, based on digital differential display analyses of 760 human Unigenes. In the present work, we reanalyzed the gene expression data in many tissues of human and mouse for a large number of genes almost covering the respective w...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章
doi:10.1159/000086378
更新日期:2005-01-01 00:00:00
abstract::Chromatin diminution (CD) is a phenomenon of programmed DNA elimination which takes place in early embryogenesis in some eukaryotes. The mechanism and biological role of CD remain largely unknown. During CD in the freshwater copepod Cyclops kolensis, the genome of cells of the somatic lineage is reorganized and reduce...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章,评审
doi:10.1159/000494157
更新日期:2018-01-01 00:00:00
abstract::Since the discovery of SRY/SRY as a testis-determining gene on the mammalian Y chromosome in 1990, extensive studies have been carried out on the immediate target of SRY/SRY and genes functioning in the course of testis development. Comparative studies in non-mammalian vertebrates including birds have failed to find a...
journal_title:Cytogenetic and genome research
pub_type: 杂志文章,评审
doi:10.1159/000071599
更新日期:2002-01-01 00:00:00