Abstract：
:The best possible allergen immunotherapy clinical outcomes require the provision of high quality and safe allergen immunotherapy extract preparations. Evolving national guidelines and regulatory bodies have devoted special attention to the safe compounding of sterile products, including allergen extracts. It is incumbent upon allergists preparing extract treatment sets for patients to be familiar with and adopt training, procedures and safety measures that lead to standardized high quality products. Preparers and supervisors must maintain ongoing competency in aseptic technique and prescribing principles, such as probable effective dose ranges, allergen cross-reactivity, and separation of high protease-containing extracts from susceptible extracts. Accordingly, knowledge and application of vial labeling, diluent selection, standard operating procedures, mixing log documentation, and mixing condition principles are a necessity. Although there have been no instances of infectious complications from allergen immunotherapy in a century of clinical practice, continued vigilance in the use of measures that ensure extract sterility is paramount. A review of allergen immunotherapy preparation recommendations and best practices based on published national guidelines is presented. Further study of preparation measures and prescribing principles will continue to advance the practice of allergen immunotherapy and offer opportunities for refinement of current recommendations.
journal_name
Curr Allergy Asthma Repjournal_title
Current allergy and asthma reportsauthors
Nelson MR,Petersen MM,Wolverton WO,Mikita CPdoi
10.1007/s11882-013-0362-zsubject
Has Abstractpub_date
2013-08-01 00:00:00pages
399-405issue
4eissn
1529-7322issn
1534-6315journal_volume
13pub_type
杂志文章,评审abstract：PURPOSE OF REVIESW:Local respiratory allergy (LRA) is an eosinophilic phenotype of chronic airway disease. Three entities have been described within the LRA spectrum: local allergic rhinitis (LAR) and local allergic asthma (LAA) in non-atopic patients, and dual allergic rhinitis (DAR) in atopic patients (coexistence of...
journal_title：Current allergy and asthma reports
pub_type： 杂志文章,评审
doi：10.1007/s11882-020-00920-w
更新日期：2020-05-19 00:00:00
abstract：PURPOSE OF REVIEW:An update on new therapies currently approved or potentially useful in the future for the management of patients suffering moderate-to-severe atopic dermatitis. RECENT FINDINGS:New pathogenic mechanisms involved in atopic dermatitis have permitted to propose novel therapeutic approaches devised to co...
journal_title：Current allergy and asthma reports
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doi：10.1007/s11882-019-0849-3
更新日期：2019-02-28 00:00:00
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journal_title：Current allergy and asthma reports
pub_type： 杂志文章,评审
doi：10.1007/s11882-003-0023-8
更新日期：2003-03-01 00:00:00
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journal_title：Current allergy and asthma reports
pub_type： 杂志文章,评审
doi：10.1007/s11882-014-0496-7
更新日期：2015-02-01 00:00:00
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journal_title：Current allergy and asthma reports
pub_type： 杂志文章,评审
doi：10.1007/s11882-020-00933-5
更新日期：2020-06-06 00:00:00
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journal_title：Current allergy and asthma reports
pub_type： 杂志文章,评审
doi：10.1007/s11882-005-0051-7
更新日期：2005-01-01 00:00:00
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journal_title：Current allergy and asthma reports
pub_type： 杂志文章
doi：10.1007/s11882-014-0468-y
更新日期：2014-10-01 00:00:00
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journal_title：Current allergy and asthma reports
pub_type： 杂志文章,评审
doi：10.1007/s11882-002-0032-z
更新日期：2002-01-01 00:00:00
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journal_title：Current allergy and asthma reports
pub_type： 杂志文章,评审
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更新日期：2003-09-01 00:00:00
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journal_title：Current allergy and asthma reports
pub_type： 杂志文章,评审
doi：10.1007/s11882-007-0029-8
更新日期：2007-04-01 00:00:00
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journal_title：Current allergy and asthma reports
pub_type： 杂志文章,评审
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更新日期：2008-09-01 00:00:00
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journal_title：Current allergy and asthma reports
pub_type： 杂志文章,评审
doi：10.1007/s11882-018-0758-x
更新日期：2018-01-19 00:00:00
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journal_title：Current allergy and asthma reports
pub_type： 杂志文章,评审
doi：10.1007/s11882-009-0045-y
更新日期：2009-07-01 00:00:00
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journal_title：Current allergy and asthma reports
pub_type： 杂志文章,评审
doi：10.1007/s11882-002-0077-z
更新日期：2002-09-01 00:00:00
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journal_title：Current allergy and asthma reports
pub_type： 杂志文章,评审
doi：10.1007/s11882-014-0462-4
更新日期：2014-09-01 00:00:00
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journal_title：Current allergy and asthma reports
pub_type： 杂志文章,评审
doi：10.1007/s11882-019-0846-6
更新日期：2019-02-22 00:00:00
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journal_title：Current allergy and asthma reports
pub_type： 杂志文章,评审
doi：10.1007/s11882-006-0048-x
更新日期：2006-03-01 00:00:00
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journal_title：Current allergy and asthma reports
pub_type： 杂志文章,评审
doi：10.1007/s11882-020-00974-w
更新日期：2020-10-12 00:00:00
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journal_title：Current allergy and asthma reports
pub_type： 杂志文章,评审
doi：10.1007/s11882-015-0538-9
更新日期：2015-07-01 00:00:00
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journal_title：Current allergy and asthma reports
pub_type： 杂志文章,评审
doi：10.1007/s11882-008-0091-x
更新日期：2008-11-01 00:00:00
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journal_title：Current allergy and asthma reports
pub_type： 杂志文章
doi：10.1007/s11882-010-0103-5
更新日期：2010-05-01 00:00:00
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journal_title：Current allergy and asthma reports
pub_type： 杂志文章,评审
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更新日期：2015-08-01 00:00:00
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journal_title：Current allergy and asthma reports
pub_type： 杂志文章,评审
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更新日期：2002-11-01 00:00:00
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journal_title：Current allergy and asthma reports
pub_type： 杂志文章,评审
doi：10.1007/s11882-002-0005-2
更新日期：2002-03-01 00:00:00
abstract：:Chronic rhinosinusitis (CRS) is an inflammatory disorder affecting the nose and paranasal sinuses. Although bacteria have long been implicated as pathogens in most forms of CRS, fungi may be responsible for some forms. Several recent studies demonstrated that, under optimal conditions, fungi can be identified in the n...
journal_title：Current allergy and asthma reports
pub_type： 杂志文章,评审
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更新日期：2008-04-01 00:00:00
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journal_title：Current allergy and asthma reports
pub_type： 杂志文章,评审
doi：10.1007/s11882-020-00949-x
更新日期：2020-07-09 00:00:00
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journal_title：Current allergy and asthma reports
pub_type： 杂志文章,评审
doi：10.1007/s11882-018-0770-1
更新日期：2018-02-22 00:00:00
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journal_title：Current allergy and asthma reports
pub_type： 杂志文章,评审
doi：10.1007/s11882-012-0269-0
更新日期：2012-08-01 00:00:00
abstract：:The nasal mucosa is a complex tissue that interacts with its environment and effects local and systemic changes. Receptors in the nose receive signals from stimuli, and respond locally through afferent, nociceptive, type C neurons to elicit nasonasal reflex responses mediated via cholinergic neurons. This efferent lim...
journal_title：Current allergy and asthma reports
pub_type： 杂志文章,评审
doi：10.1007/s11882-007-0007-1
更新日期：2007-05-01 00:00:00
abstract：:Stem cell transplant (SCT) has long been the standard of care for several hematologic, immunodeficient, and oncologic disorders. Recently, SCT has become an increasingly utilized therapy for refractory autoimmune rheumatologic disorders (ARDs). The efficacy of SCT in ARDs has been attributed to resetting an aberrant i...
journal_title：Current allergy and asthma reports
pub_type： 杂志文章,评审
doi：10.1007/s11882-012-0298-8
更新日期：2012-12-01 00:00:00
