Challenges for allergy diagnosis in regions with complex pollen exposures.

abstract：:Multiple sclerosis (MS) is the most common cause of chronic neurologic disability in young people. Genetic susceptibility and unidentified environmental triggers appear to be necessary in order to result in disease. MS is an extraordinarily complex trait with evidence of heterogeneity at clinical, pathologic, and ther...

journal_title：Current allergy and asthma reports

authors： Heard RN

更新日期：2007-07-01 00:00:00

abstract：:T cells are major protagonists of immune-mediated adverse drug eruptions. Immunohistochemical observation as well as isolation and functional characterization of T cells infiltrating the affected tissues provided new insights into the pathomechanisms of the diverse clinical manifestations of drug hypersensitivity, and...

journal_title：Current allergy and asthma reports

authors： Cavani A,De Pità O

更新日期：2006-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Olfactory functioning disturbances are common following traumatic brain injury (TBI) having a significant impact on quality of life. A spontaneous recovery of the olfactory function over time may occur in TBI patients. Although there is no standard treatment for patients with posttraumatic olfactory l...

journal_title：Current allergy and asthma reports

authors： Marin C,Langdon C,Alobid I,Mullol J

更新日期：2020-07-09 00:00:00

abstract：PURPOSE OF REVIEW:There has been an explosion in the number of published systematic reviews on chronic rhinosinusitis in the last decade. RECENT FINDINGS:While the aim of these reviews in facilitating evidence-based practice is laudable, poor quality reviews may contain significant bias that can mislead a non-discerni...

journal_title：Current allergy and asthma reports

authors： Walker A,Hopkins C

更新日期：2018-02-16 00:00:00

abstract：:The increased prevalence of atopic diseases, atopic dermatitis, allergic rhinitis, and asthma has been described as an epidemic. New approaches in the fight against allergic diseases are called for, the target being the persistence of the atopic T helper 2-skewed immune responder pattern beyond infancy. Atopic dermati...

journal_title：Current allergy and asthma reports

authors： Isolauri E

更新日期：2004-07-01 00:00:00

abstract：:Nonspecific lipid transfer proteins (LTPs) are important allergens in fruits, vegetables, nuts, pollen, and latex. Despite their wide distribution throughout the plant kingdom, their clinical relevance is largely confined to the Mediterranean area. As they can sensitize via the gastrointestinal tract, LPTs are conside...

journal_title：Current allergy and asthma reports

authors： Egger M,Hauser M,Mari A,Ferreira F,Gadermaier G

更新日期：2010-09-01 00:00:00

abstract：:Respiratory viruses appear to play a central role in asthma pathogenesis. In addition to a major role in triggering asthma exacerbations, viral infections early in life may play a role in disease development. Although defensins were initially identified as antimicrobial peptides, recent studies have demonstrated that ...

journal_title：Current allergy and asthma reports

authors： Proud D

更新日期：2006-02-01 00:00:00

abstract：:Chronic rhinosinusitis (CRS) is a chronic inflammatory disease of the upper airways of which two major phenotypes exist, CRS without nasal polyps (CRSsNP) and CRS with nasal polyps (CRSwNP). Some patients with CRS have suboptimal response to current guideline treatments. These patients remain severe and uncontrolled b...

journal_title：Current allergy and asthma reports

authors： López-Chacón M,Mullol J,Pujols L

更新日期：2015-05-01 00:00:00

abstract：PURPOSE OF REVIEW:This review aims to update the information available on the prevalence, clinical picture, diagnostic methods, and treatment of urticarias induced by external physical stimuli. RECENT FINDINGS:Physical urticarias are present in up to 5% of the general population, and in 10 to 50% of patients with chro...

journal_title：Current allergy and asthma reports

authors： Sánchez-Borges M,González-Aveledo L,Caballero-Fonseca F,Capriles-Hulett A

更新日期：2017-08-01 00:00:00

abstract：:Oral food challenges are the gold-standard diagnostic investigation for diagnosing food allergy. They allow a subject to consume an age-appropriate portion of allergenic food under surveillance to assess whether a reproducible immune-mediated adverse response is demonstrated. The specific design of food challenge must...

journal_title：Current allergy and asthma reports

authors： Feeney M,Marrs T,Lack G,Du Toit G

更新日期：2015-08-01 00:00:00

abstract：:Epinephrine can be lifesaving in episodes of anaphylaxis, yet it is underprescribed and underused. Tracking of epinephrine refills over time for patients with a diagnosis of anaphylaxis has not been reported. This study reports on the refill history of 14,677 patients in a large HMO who received an initial dispensing ...

journal_title：Current allergy and asthma reports

authors： Kaplan MS,Jung SY,Chiang ML

更新日期：2011-02-01 00:00:00

abstract：:IgG4 is the least abundant subclass of IgG in normal human serum, but elevated IgG4 levels are triggered in response to a chronic antigenic stimulus and inflammation. Since the immune system is exposed to tumor-associated antigens over a relatively long period of time, and tumors notoriously promote inflammation, it i...

journal_title：Current allergy and asthma reports

authors： Crescioli S,Correa I,Karagiannis P,Davies AM,Sutton BJ,Nestle FO,Karagiannis SN

更新日期：2016-01-01 00:00:00

abstract：:Orbital myositis is an inflammatory process that primarily involves the extraocular muscles and most commonly affects young adults in the third decade of life, with a female predilection. Clinical characteristics of orbital myositis include orbital and periorbital pain, ocular movement impairment, diplopia, proptosis,...

journal_title：Current allergy and asthma reports

authors： Costa RM,Dumitrascu OM,Gordon LK

更新日期：2009-07-01 00:00:00

abstract：:The environment is a major contributor to allergic disease, and great effort is being expended to identify the chemical pollutants and allergens that make a significant impact. Exposure to high levels of ozone, sulfur dioxide, nitrogen dioxide, and diesel exhaust particles is known to reduce lung function. Studies con...

journal_title：Current allergy and asthma reports

authors： Levetin E,Van de Water P

更新日期：2001-11-01 00:00:00

abstract：PURPOSE OF REVIEW:This review aims to provide an update of recent advances in the epidemiology, clinical features and diagnosis, and management of food-induced anaphylaxis (FIA). RECENT FINDINGS:Food allergy prevalence and FIA rates continue to rise, but FIA fatalities are stable. Basophil and mast cell activation tes...

journal_title：Current allergy and asthma reports

authors： Parrish CP,Kim H

更新日期：2018-06-14 00:00:00

abstract：:Asthma is an episodic respiratory syndrome caused by several pathogenic processes. This recurrent syndrome is associated with an accelerated decline in lung function and increase in airway obstruction over time. The reduced lung function is a consequence of tissue restructuring of all the components of the airway wall...

journal_title：Current allergy and asthma reports

authors： Bossé Y,Paré PD,Seow CY

更新日期：2008-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Food allergy is a growing health problem worldwide that impacts millions of individuals. Current treatment options are limited and strict dietary avoidance remains the standard of care. Immunotherapy using whole, native allergens is under active clinical investigation but harbors the risk of severe si...

journal_title：Current allergy and asthma reports

authors： Yang L,Kulis M

更新日期：2019-02-22 00:00:00

abstract：:Traditionally, symptoms are important patient-oriented outcomes in asthma treatment, and assessment of symptoms is an essential component of assessing asthma control. However, variable airways obstruction, airways hyperresponsiveness and chronic inflammation are key components of the asthma syndrome, and correlations ...

journal_title：Current allergy and asthma reports

authors： Nuijsink M,De Jongste JC,Pijnenburg MW

更新日期：2013-10-01 00:00:00

abstract：:Guillain-Barré syndrome (GBS) is a classic failure of the immune system with a life-threatening attack upon a critical self-component. The active phase of the disease is short, concordant with the latency of a primary adaptive immune response. Triggers for GBS include infection and (rarely) vaccination; cross-reactivi...

journal_title：Current allergy and asthma reports

authors： Hardy TA,Blum S,McCombe PA,Reddel SW

更新日期：2011-06-01 00:00:00

abstract：:The role of distinct CD4(+) T-cell populations in regulating the nature and strength of immune responses is well documented and in the past has principally focused on the cross-regulation of T-helper type 1 (Th1) and Th2 cells, which secrete interferon-gamma and interleukin-4, respectively. However, the identification...

journal_title：Current allergy and asthma reports

authors： McGuirk P,Higgins SC,Mills KH

更新日期：2010-01-01 00:00:00

abstract：PURPOSE OF REVIEW:This study aimed to review important hidden causes of anaphylaxis in ingestants, non-ingestants, and uncommon settings. RECENT FINDINGS:Multiple new and elusive causes of anaphylaxis have been described over the past 35 years. Further research is required to identify the epidemiology, pathophysiology...

journal_title：Current allergy and asthma reports

authors： Nanagas VC,Baldwin JL,Karamched KR

更新日期：2017-07-01 00:00:00

abstract：:Major progress has been made during the past few years in developing a better understanding of the genetic basis of asthma, which has led to the identification of several chromosomal regions and loci showing linkage to and association with asthma and asthma-related phenotypes. Recent positional cloning approaches have...

journal_title：Current allergy and asthma reports

authors： Park HS,Kim SH,Park CS

更新日期：2006-03-01 00:00:00

abstract：:Differences in asthma prevalence have been described across different populations, suggesting that genetic ancestry can play an important role in this disease. In fact, several studies have demonstrated an association between African ancestry with increased asthma susceptibility and severity, higher immunoglobulin E l...

journal_title：Current allergy and asthma reports

authors： Hernandez-Pacheco N,Flores C,Oh SS,Burchard EG,Pino-Yanes M

更新日期：2016-07-01 00:00:00

abstract：:DiGeorge syndrome is characterized by conotruncal cardiac defects, hypocalcemia, and a hypoplastic thymus. Many, but not all, patients have a heterozygous deletion of chromosome 22q11.2. In its most severe form, it represents a devastating syndrome with high mortality. Patients with severe immunodeficiency are candida...

journal_title：Current allergy and asthma reports

authors： Sullivan KE

更新日期：2001-09-01 00:00:00

abstract：:Anaphylaxis is a potentially life-threatening allergic reaction characterized by a syndrome of dermatologic and systemic signs and symptoms, at times including cardiovascular collapse from distributive shock. Although it is recognized that the incidence of anaphylaxis is increasing, the extent of its prevalence, both ...

journal_title：Current allergy and asthma reports

authors： Matasar MJ,Neugut AI

更新日期：2003-01-01 00:00:00

abstract：:Although the smoking prevalence in the United States continues to decline since the Surgeon General's first report in 1964, certain vulnerable populations continue to be disproportionately affected by the adverse consequences of tobacco smoke exposure. Children are particularly vulnerable to exposure and are likely to...

journal_title：Current allergy and asthma reports

authors： Ciaccio CE,Gentile D

更新日期：2013-12-01 00:00:00

abstract：:Urticaria can present acutely and be self-limiting or become chronic and persist for weeks, months, or years. In either case, the condition may have a significant impact on the patient's quality of life. Two major consensus groups, the EAACI/WAO and the AAAAI/ACAAI Joint Task Force, have written guidelines on the diag...

journal_title：Current allergy and asthma reports

authors： Fine LM,Bernstein JA

更新日期：2015-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Focusing on the strict relationship between house dust mites and crustaceans from the allergenic point of view. RECENT FINDINGS:The well-known tropomyosin was considered for years as the cross-reacting allergen between shrimp and house dust mites. In the last few years, several allergens not only in ...

journal_title：Current allergy and asthma reports

authors： Asero R,Pravettoni V,Scala E,Villalta D

更新日期：2020-03-06 00:00:00

abstract：:Omalizumab is a recently developed monoclonal anti-IgE antibody. Clinical trials have demonstrated its efficacy in patients with moderate-to-severe and severe or poorly controlled allergic asthma, in patients with seasonal and perennial allergic disease, and in subjects with concomitant asthma and allergic rhinitis. P...

journal_title：Current allergy and asthma reports

authors： Sandström T

更新日期：2005-03-01 00:00:00

abstract：:Natural oils include mineral oil with emollient, occlusive, and humectant properties and the plant-derived essential, coconut, and other vegetable oils, composed of triglycerides that microbiota lipases hydrolyze into glycerin, a potent humectant, and fatty acids (FAs) with varying physico-chemical properties. Unsatur...

journal_title：Current allergy and asthma reports

authors： Verallo-Rowell VM,Katalbas SS,Pangasinan JP

更新日期：2016-07-01 00:00:00