Suicide risk in people with epilepsy taking antiepileptic drugs.

abstract：OBJECTIVES:In this study, we aimed to determine the role of genetic variations within the zinc finger protein 804A (ZNF804A) gene, a candidate for a psychosis risk-conferring gene, in the development of schizophrenia (SZ) and bipolar disorder (BP) in the Korean population. METHODS:A total of 921 patients with SZ, bipo...

journal_title：Bipolar disorders

authors： Baek JH,Ha K,Kim Y,Yang SY,Cho EY,Choi Y,Ryu S,Lee YS,Park T,Hong KS

更新日期：2017-06-01 00:00:00

abstract：INTRODUCTION:Suicide is a multicausal human behavior, with devastating and immensely distressing consequences. Its prevalence is estimated to be 20-30 times greater in patients with bipolar disorders than in the general population. The burden of suicide and its high prevalence in bipolar disorders make it imperative th...

journal_title：Bipolar disorders

authors： Malhi GS,Outhred T,Das P,Morris G,Hamilton A,Mannie Z

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVES:Considerable preclinical biochemical and behavioral data suggest that protein kinase C inhibition would bring about antimanic effects. Notably, the structurally highly dissimilar antimanic agents lithium and valproate, when administered in therapeutically relevant paradigms, attenuate protein kinase C [corre...

journal_title：Bipolar disorders

authors： Zarate CA Jr,Singh JB,Carlson PJ,Quiroz J,Jolkovsky L,Luckenbaugh DA,Manji HK

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVES:Previous studies found evidence for thinner frontotemporal cortices in bipolar disorder (BD), yet whether this represents a stable disease trait or an effect of mood episodes remains unknown. Here, we assessed the reproducibility of thinner frontotemporal cortices in BD type II, compared longitudinal changes...

journal_title：Bipolar disorders

authors： Zak N,Bøen E,Boye B,Andreassen OA,Doan NT,Malt UF,Westlye LT,Elvsåshagen T

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVES:Manic patients exhibit impaired verbal learning and memory, particularly following longstanding illness. However, it is unclear whether recognition and recall performance are differentially influenced by a manic mood state. METHODS:To examine this issue, we administered the California Verbal Learning Test a...

journal_title：Bipolar disorders

authors： Fleck DE,Shear PK,Zimmerman ME,Getz GE,Corey KB,Jak A,Lebowitz BK,Strakowski SM

更新日期：2003-10-01 00:00:00

abstract：:Research into postnatal mood disorders to date has concentrated on depressive syndromes of varying severity and full-blown acute puerperal mania. However, clinical experience, backed up by a review of the literature, indicates that milder hypomanic symptoms also occur in the early puerperium. Although these symptoms m...

journal_title：Bipolar disorders

authors： Heron J,Craddock N,Jones I

更新日期：2005-04-01 00:00:00

abstract：OBJECTIVE:To investigate whether treatment with lithium in patients with mania or bipolar disorder is associated with a decreased rate of subsequent dementia. METHODS:Linkage of register data on prescribed lithium in all patients discharged from psychiatric health care service with a diagnosis of mania or bipolar diso...

journal_title：Bipolar disorders

authors： Kessing LV,Forman JL,Andersen PK

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVES:To investigate whether first admission with mania is associated with the occurrence of death in the family or with major stressful life events and to explore whether the associations change with age. METHODS:Case register study with linkage of the Danish Psychiatric Central Research Register, including data...

journal_title：Bipolar disorders

authors： Kessing LV,Agerbo E,Mortensen PB

更新日期：2004-04-01 00:00:00

abstract：:The Diagnostic Guidelines Task Force of the International Society for Bipolar Disorders (ISBD) presents in this document and this special issue a summary of the current nosological status of bipolar illness, a discussion of possible revisions to current DSM-IV and ICD-10 definitions, an examination of the relevant lit...

journal_title：Bipolar disorders

authors： Ghaemi SN,Bauer M,Cassidy F,Malhi GS,Mitchell P,Phelps J,Vieta E,Youngstrom E,ISBD Diagnostic Guidelines Task Force.

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVE:Bipolar disorder is associated with a high frequency of both completed suicides and suicide attempts. The primary aim of this study was to identify clinical predictors of suicide attempts in subjects with bipolar disorder. METHODS:We studied 336 subjects with a diagnosis of bipolar I, bipolar II, or schizoaf...

journal_title：Bipolar disorders

authors： Dalton EJ,Cate-Carter TD,Mundo E,Parikh SV,Kennedy JL

更新日期：2003-02-01 00:00:00

abstract：OBJECTIVES:Lithium is often the mood stabilizer of choice for the treatment of type I bipolar disorder. However, side effects as well as the narrow therapeutic dosing range often complicate its use. Lithium toxicity can be fatal and its serum level needs to be closely monitored, especially at the time of introduction a...

journal_title：Bipolar disorders

authors： Lazarczyk MJ,Giannakopoulos P

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVES:Extensive preclinical and clinical evidence suggests mitochondrial dysfunction in bipolar disorder. Studies of brain energy metabolism in bipolar disorder suggest an impairment of energy generation by mitochondrial oxidative phosphorylation. Lithium is an effective drug widely used in treating bipolar disord...

journal_title：Bipolar disorders

authors： Maurer IC,Schippel P,Volz HP

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVES:We combined multimodal functional magnetic resonance imaging (fMRI) and structural magnetic resonance imaging to probe abnormalities in brain circuits underpinning episodic memory performance deficits in patients with bipolar disorder (BD). METHODS:We acquired whole-brain fMRI data in 21 patients with BD an...

journal_title：Bipolar disorders

authors： Oertel-Knöchel V,Reinke B,Feddern R,Knake A,Knöchel C,Prvulovic D,Pantel J,Linden DE

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:The increased standardized mortality ratio (SMR) from cardiovascular disease (CVD) in women with bipolar disorder (BD), relative to men with BD and individuals of both sexes in the general population, provides the impetus to identify factors that contribute to the differential association of obesity with BD i...

journal_title：Bipolar disorders

authors： Baskaran A,Cha DS,Powell AM,Jalil D,McIntyre RS

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Neurovascular abnormalities are relevant to the pathophysiology of bipolar disorder (BD), which can be assessed using cerebral blood flow (CBF) imaging. CBF alterations have been identified in BD, but studies to date have been small and inconclusive. We aimed to determine cortical gray matter CBF (GM-CBF) di...

journal_title：Bipolar disorders

authors： Zeng V,Lizano P,Bolo NR,Lutz O,Brady R Jr,Ivleva EI,Dai W,Clementz B,Tamminga C,Pearlson G,Keshavan M

更新日期：2020-06-24 00:00:00

abstract：OBJECTIVE:Although second-generation antipsychotics (SGAs) are widely used in treating schizophrenia and bipolar disorder, their effects on dyslipidemia, glucose intolerance, metabolic syndrome (MetS), and coronary heart disease (CHD) risk are less well documented for bipolar disorder. We compared bipolar disorder and ...

journal_title：Bipolar disorders

authors： Correll CU,Frederickson AM,Kane JM,Manu P

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVES:Although olfactory abnormalities are well established in schizophrenia, considerably less work has examined olfactory performance in other neuropsychiatric conditions. In the current study, we examined odor identification, odor discrimination, detection threshold, and odor hedonic processing performance in i...

journal_title：Bipolar disorders

authors： Kamath V,Paksarian D,Cui L,Moberg PJ,Turetsky BI,Merikangas KR

更新日期：2018-09-01 00:00:00

abstract：AIMS:To systematically review the literature on the efficacy and tolerability of the major chronotherapeutic treatments of bipolar disorders (BD)-bright light therapy (LT), dark therapy (DT), treatments utilizing sleep deprivation (SD), melatonergic agonists (MA), interpersonal social rhythm therapy (IPSRT), and cognit...

journal_title：Bipolar disorders

authors： Gottlieb JF,Benedetti F,Geoffroy PA,Henriksen TEG,Lam RW,Murray G,Phelps J,Sit D,Swartz HA,Crowe M,Etain B,Frank E,Goel N,Haarman BCM,Inder M,Kallestad H,Jae Kim S,Martiny K,Meesters Y,Porter R,Riemersma-van der L

更新日期：2019-12-01 00:00:00

abstract：OBJECTIVES:Mental imagery abnormalities occur across psychopathologies and are hypothesized to drive emotional difficulties in bipolar disorder (BD). A comprehensive assessment of mental imagery in BD is lacking. We aimed to test whether (i) mental imagery abnormalities (abnormalities in cognitive stages and subjective...

journal_title：Bipolar disorders

authors： Di Simplicio M,Renner F,Blackwell SE,Mitchell H,Stratford HJ,Watson P,Myers N,Nobre AC,Lau-Zhu A,Holmes EA

更新日期：2016-12-01 00:00:00

abstract：:Lithium, the major drug used to treat manic depressive illness, robustly protects cultured rat brain neurons from glutamate excitotoxicity mediated by N-methyl-D-aspartate (NMDA) receptors. The lithium neuroprotection against glutamate excitotoxiciy is long-lasting, requires long-term pretreatment and occurs at therap...

journal_title：Bipolar disorders

authors： Chuang DM,Chen RW,Chalecka-Franaszek E,Ren M,Hashimoto R,Senatorov V,Kanai H,Hough C,Hiroi T,Leeds P

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVES:To determine the effects of mood and additional clinical variables on different domains of current interviewer-rated social adjustment reflecting the reported behaviour of patients with bipolar disorder (BD). METHOD:Multi-center cross-sectional study employing multiple linear regression to investigate wheth...

journal_title：Bipolar disorders

authors： Morriss R,Scott J,Paykel E,Bentall R,Hayhurst H,Johnson T

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVES:Population isolates offer several advantages for those hoping to identify predisposition genes for bipolar disorder (BP). In this review article, the rationale for performing gene mapping studies in this type of population and the results of genetic mapping studies performed to date in population isolates ar...

journal_title：Bipolar disorders

authors： Escamilla MA

更新日期：2001-12-01 00:00:00

abstract：OBJECTIVES:To evaluate the antimanic efficacy and safety of paliperidone extended-release (ER) tablets in patients with bipolar I disorder. METHODS:This study included a 3-week, double-blind, acute treatment phase (paliperidone ER versus placebo, with quetiapine as control), and a 9-week, double-blind, maintenance pha...

journal_title：Bipolar disorders

authors： Vieta E,Nuamah IF,Lim P,Yuen EC,Palumbo JM,Hough DW,Berwaerts J

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVES:Bipolar disorder (BD) is a common and highly disabling disease characterized by substantial cognitive and functional impairment. The exact neurobiological mechanisms underlying the expression of symptoms in this condition remain unknown but there is growing evidence that glutamate might play an important rol...

journal_title：Bipolar disorders

authors： Gigante AD,Bond DJ,Lafer B,Lam RW,Young LT,Yatham LN

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVES:To compare the dimensional psychopathology in offspring of parents with bipolar disorder (BP) with offspring of community control parents as assessed by the Child Behavior Checklist (CBCL). METHODS:Offspring of parents with BP, who were healthy or had non-BP disorders (any psychiatric disorder other than BP...

journal_title：Bipolar disorders

authors： Diler RS,Birmaher B,Axelson D,Obreja M,Monk K,Hickey MB,Goldstein B,Goldstein T,Sakolsky D,Iyengar S,Brent D,Kupfer D

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVE:Despite effective pharmacological treatments for bipolar disorder, we still lack a comprehensive pathophysiological model of the illness. Recent neurobiological research has implicated a number of key brain regions and neuronal components in the behavioural and cognitive manifestations of bipolar disorder. Do...

journal_title：Bipolar disorders

authors： Cousins DA,Butts K,Young AH

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Neurocognitive deficits are prevalent, persistent, and implicated as mediators of functional impairment in adults with bipolar disorder. Notwithstanding progress in the development of pharmacological treatments for various phases of bipolar disorder, no available treatment has been proven to be reliably effi...

journal_title：Bipolar disorders

authors： McIntyre RS,Soczynska JK,Woldeyohannes HO,Miranda A,Vaccarino A,Macqueen G,Lewis GF,Kennedy SH

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:An emerging body of evidence supports a role for dysfunctional purinergic neurotransmission in mood disorders. Adenosine agonists have been shown to have properties similar to those of dopamine antagonists; there is a well-characterized interaction between adenosine and dopamine receptors in the ventral stria...

journal_title：Bipolar disorders

authors： Weiser M,Burshtein S,Gershon AA,Marian G,Vlad N,Grecu IG,Tocari E,Tiugan A,Hotineanu M,Davis JM

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVES:Many morphometric magnetic resonance imaging (MRI) studies that have investigated the presence of gray matter (GM) volume abnormalities associated with the diagnosis of bipolar disorder (BD) have reported conflicting findings. None of these studies has compared patients with recent-onset psychotic BD with as...

journal_title：Bipolar disorders

authors： de Azevedo-Marques Périco C,Duran FL,Zanetti MV,Santos LC,Murray RM,Scazufca M,Menezes PR,Busatto GF,Schaufelberger MS

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:To investigate the diagnostic profile of women referred for postpartum depression. METHODS:Fifty-six women seen consecutively with the referral diagnosis of postpartum depression were administered structured instruments to gather information about their DSM-IV Axis I diagnoses. RESULTS:In terms of frequency...

journal_title：Bipolar disorders

authors： Sharma V,Khan M,Corpse C,Sharma P

更新日期：2008-09-01 00:00:00