Abstract:
:Volcanoes are increasingly recognized as agents and recorders of global climate variability, although deciphering the linkages between planetary climate and volcanism is still in its infancy. The growth and emergence of subaqueous volcanoes produce passage zones, which are stratigraphic surfaces marking major transitions in depositional environments. In glaciovolcanic settings, they record the elevations of syn-eruptive englacial lakes. Thus, they allow for forensic recovery of minimum ice thicknesses. Here we present the first description of a passage zone preserved entirely within pyroclastic deposits, marking the growth of a tephra cone above the englacial lake level. Our discovery requires extension of the passage-zone concept to accommodate explosive volcanism and guides future studies of hundreds of glaciovolcanic edifices on Earth and Mars. Our recognition of pyroclastic passage zones increases the potential for recovering transient paleolake levels, improving estimates of paleo-ice thicknesses and providing new constraints on paleoclimate models that consider the extents and timing of planetary glaciations.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Russell JK,Edwards BR,Porritt LAdoi
10.1038/ncomms2829subject
Has Abstractpub_date
2013-01-01 00:00:00pages
1788issn
2041-1723pii
ncomms2829journal_volume
4pub_type
杂志文章abstract::The 2018 summit and flank eruption of Kīlauea Volcano was one of the largest volcanic events in Hawai'i in 200 years. Data suggest that a backup in the magma plumbing system at the long-lived Pu'u 'Ō'ō eruption site caused widespread pressurization in the volcano, driving magma into the lower flank. The eruption evolv...
journal_title:Nature communications
pub_type: 杂志文章,评审
doi:10.1038/s41467-020-19190-1
更新日期:2020-11-06 00:00:00
abstract::The shelterin protein TRF2 is essential for chromosome-end protection. Depletion of TRF2 causes chromosome end-to-end fusions, initiating genomic instability that can be cancer promoting. Paradoxically, significant increased levels of TRF2 are observed in a subset of human cancers. Experimental overexpression of TRF2 ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms10132
更新日期:2015-12-07 00:00:00
abstract::Metabolism is coordinated among tissues and organs via neuronal signals. Levels of circulating amino acids (AAs), which are elevated in obesity, activate the intracellular target of rapamycin complex-1 (mTORC1)/S6kinase (S6K) pathway in the liver. Here we demonstrate that hepatic AA/mTORC1/S6K signalling modulates sys...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms8940
更新日期:2015-08-13 00:00:00
abstract::Anti-Müllerian hormone (AMH) plays crucial roles in sexual differentiation and gonadal functions. However, the possible extragonadal effects of AMH on the hypothalamic-pituitary-gonadal axis remain unexplored. Here we demonstrate that a significant subset of GnRH neurons both in mice and humans express the AMH recepto...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms10055
更新日期:2016-01-12 00:00:00
abstract::6-Phosphogluconate dehydrogenase (6PGD) is a key enzyme that converts 6-phosphogluconate into ribulose-5-phosphate with NADP+ as cofactor in the pentose phosphate pathway (PPP). 6PGD is commonly upregulated and plays important roles in many human cancers, while the mechanism underlying such roles of 6PGD remains elusi...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-08921-8
更新日期:2019-03-01 00:00:00
abstract::Foldamers provide an attractive medium to test the mechanisms by which biological macromolecules fold into complex three-dimensional structures, and ultimately to design novel protein-like architectures with properties unprecedented in nature. Here, we describe a large cage-like structure formed from an amphiphilic ar...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms4581
更新日期:2014-04-07 00:00:00
abstract::Cyclic nucleotide-binding (CNB) domains allosterically regulate the activity of proteins with diverse functions, but the mechanisms that enable the cyclic nucleotide-binding signal to regulate distant domains are not well understood. Here we use optical tweezers and molecular dynamics to dissect changes in folding ene...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-11930-2
更新日期:2019-09-04 00:00:00
abstract::Carotenoid cleavage dioxygenases (CCDs) form hormones and signaling molecules. Here we show that a member of an overlooked plant CCD subfamily from rice, that we name Zaxinone Synthase (ZAS), can produce zaxinone, a novel apocarotenoid metabolite in vitro. Loss-of-function mutants (zas) contain less zaxinone, exhibit ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-08461-1
更新日期:2019-02-18 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Nature communications
pub_type: 杂志文章,已发布勘误
doi:10.1038/s41467-020-17694-4
更新日期:2020-07-23 00:00:00
abstract::A challenge for neuroscience is to understand the conscious and unconscious processes underlying construction of willed actions. We investigated the neural substrate of human motor awareness during awake brain surgery. In a first experiment, awake patients performed a voluntary hand motor task and verbally monitored t...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-14517-4
更新日期:2020-02-04 00:00:00
abstract::The interband cascade laser differs from any other class of semiconductor laser, conventional or cascaded, in that most of the carriers producing population inversion are generated internally, at semimetallic interfaces within each stage of the active region. Here we present simulations demonstrating that all previous...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms1595
更新日期:2011-12-13 00:00:00
abstract::Complex polyketides are typically associated with microbial metabolism. Here, we report that animals also make complex, microbe-like polyketides. We show there is a widespread branch of fatty acid synthase- (FAS)-like polyketide synthase (PKS) proteins, which sacoglossan animals use to synthesize complex products. The...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-16376-5
更新日期:2020-06-08 00:00:00
abstract::Enhancement of optical emission on plasmonic nanostructures is intrinsically limited by the distance between the emitter and nanostructure surface, owing to a tightly-confined and exponentially-decaying electromagnetic field. This fundamental limitation prevents efficient application of plasmonic fluorescence enhancem...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-16813-5
更新日期:2020-06-10 00:00:00
abstract::Single-crystal cathode materials for lithium-ion batteries have attracted increasing interest in providing greater capacity retention than their polycrystalline counterparts. However, after being cycled at high voltages, these single-crystal materials exhibit severe structural instability and capacity fade. Understand...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-16824-2
更新日期:2020-06-16 00:00:00
abstract::Following the discovery of high-temperature superconductivity in the La-H system, we studied the formation of new chemical compounds in the barium-hydrogen system at pressures from 75 to 173 GPa. Using in situ generation of hydrogen from NH3BH3, we synthesized previously unknown superhydride BaH12 with a pseudocubic (...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-20103-5
更新日期:2021-01-11 00:00:00
abstract::The hydrodesulfurization process is one of the cornerstones of the chemical industry, removing harmful sulfur from oil to produce clean hydrocarbons. The reaction is catalyzed by the edges of MoS2 nanoislands and is operated in hydrogen-oil mixtures at 5-160 bar and 260-380 °C. Until now, it has remained unclear how t...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-10526-0
更新日期:2019-06-11 00:00:00
abstract::Influenza virus can escape most antibodies with single mutations. However, rare antibodies broadly neutralize many viral strains. It is unclear how easily influenza virus might escape such antibodies if there was strong pressure to do so. Here, we map all single amino-acid mutations that increase resistance to broad a...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-03665-3
更新日期:2018-04-11 00:00:00
abstract::Granule cells are the dominant cell type of the olfactory bulb inhibiting mitral and tufted cells via dendrodendritic synapses; yet the factors regulating the strength of their inhibitory output, and, therefore, their impact on odour discrimination, remain unknown. Here we show that GABAAR β3-subunits are distributed ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms9950
更新日期:2015-11-23 00:00:00
abstract::Zika virus is a mosquito-borne flavivirus closely related to dengue virus that can cause severe disease in humans, including microcephaly in newborns and Guillain-Barré syndrome in adults. Specific treatments and vaccines for Zika virus are not currently available. Here, we isolate and characterize four monoclonal ant...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-07008-0
更新日期:2018-11-01 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Nature communications
pub_type: 已发布勘误
doi:10.1038/s41467-020-14339-4
更新日期:2020-01-24 00:00:00
abstract::Solid organic matter (OM) plays an essential role in the generation, migration, storage, and production of hydrocarbons from economically important shale rock formations. Electron microscopy images have documented spatial heterogeneity in the porosity of OM at nanoscale, and bulk spectroscopy measurements have documen...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-02254-0
更新日期:2017-12-19 00:00:00
abstract::Trypanosoma brucei is a protozoan parasite that evades its host's adaptive immune response by repeatedly replacing its dense variant surface glycoprotein (VSG) coat from its large genomic VSG repertoire. While the mechanisms regulating VSG gene expression and diversification have been examined extensively, the dynamic...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-00959-w
更新日期:2017-10-10 00:00:00
abstract::Here, we introduce a novel concept for the fabrication of colored materials with significantly reduced dye leaching through covalent immobilization of the desired dye using plasma-generated surface radicals. This plasma dye coating (PDC) procedure immobilizes a pre-adsorbed layer of a dye functionalized with a radical...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-03583-4
更新日期:2018-03-16 00:00:00
abstract::One of the primary contributors to forgetting is interference from overlapping memories. Intuitively, this suggests-and prominent theoretical models argue-that memory interference is best avoided by encoding overlapping memories as if they were unrelated. It is therefore surprising that reactivation of older memories ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-13377-x
更新日期:2019-11-25 00:00:00
abstract::HER2-targeted therapy has yielded a significant clinical benefit in patients with HER2+ breast cancer, yet disease relapse due to intrinsic or acquired resistance remains a significant challenge in the clinic. Here, we show that the protein phosphatase 2A (PP2A) regulatory subunit PPP2R2B is a crucial determinant of a...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-19704-x
更新日期:2020-11-18 00:00:00
abstract::No method exists to measure large-scale translation of genes in uncultured organisms in microbiomes. To overcome this limitation, we develop MetaRibo-Seq, a method for simultaneous ribosome profiling of tens to hundreds of organisms in microbiome samples. MetaRibo-Seq was benchmarked against gold-standard Ribo-Seq in ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-17081-z
更新日期:2020-06-29 00:00:00
abstract::Homologous recombination deficiency (HRD) is a defining characteristic in BRCA-deficient breast tumors caused by genetic or epigenetic alterations in key pathway genes. We investigated the frequency of BRCA1 promoter hypermethylation in 237 triple-negative breast cancers (TNBCs) from a population-based study using rep...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-17537-2
更新日期:2020-07-27 00:00:00
abstract::Batesian mimicry, in which harmless species (mimics) deter predators by deceitfully imitating the warning signals of noxious species (models), generates striking cases of phenotypic convergence that are classic examples of evolution by natural selection. However, mimicry of venomous coral snakes has remained controver...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms11484
更新日期:2016-05-05 00:00:00
abstract::Extracellular vesicles have an important function in cellular communication. Here, we show that human and mouse monocytes release TGF-β1-transporting vesicles in response to the pathogenic fungus Candida albicans. Soluble β-glucan from C. albicans binds to complement receptor 3 (CR3, also known as CD11b/CD18) on monoc...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-16241-5
更新日期:2020-05-11 00:00:00
abstract::Seismological findings show a complex scenario of plume upwellings from a deep thermo-chemical anomaly (superplume) beneath the East African Rift System (EARS). It is unclear if these geophysical observations represent a true picture of the superplume and its influence on magmatism along the EARS. Thus, it is essentia...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-13181-7
更新日期:2019-12-02 00:00:00