Comparative genomics of Bifidobacterium animalis subsp. lactis reveals a strict monophyletic bifidobacterial taxon.

Abstract:

:Strains of Bifidobacterium animalis subsp. lactis are extensively exploited by the food industry as health-promoting bacteria, although the genetic variability of members belonging to this taxon has so far not received much scientific attention. In this article, we describe the complete genetic makeup of the B. animalis subsp. lactis Bl12 genome and discuss the genetic relatedness of this strain with other sequenced strains belonging to this taxon. Moreover, a detailed comparative genomic analysis of B. animalis subsp. lactis genomes was performed, which revealed a closely related and isogenic nature of all currently available B. animalis subsp. lactis strains, thus strongly suggesting a closed pan-genome structure of this bacterial group.

journal_name

Appl Environ Microbiol

authors

Milani C,Duranti S,Lugli GA,Bottacini F,Strati F,Arioli S,Foroni E,Turroni F,van Sinderen D,Ventura M

doi

10.1128/AEM.00984-13

subject

Has Abstract

pub_date

2013-07-01 00:00:00

pages

4304-15

issue

14

eissn

0099-2240

issn

1098-5336

pii

AEM.00984-13

journal_volume

79

pub_type

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