Abstract：
UNLABELLED:The treatment of blunt splenic injuries (BSI) has undergone a significant shift away from an operative approach to a conservative treatment regimen in the last decades. Data concerning long-term follow-up of children sustaining BSI are largely confined to telephone surveys. Children treated with BSI over a 33-year period were analyzed. In order to describe the changing treatment, patients were divided into two groups: group I included children treated between 1977 and 1999; group II children treated between 2000 and 2009. Additionally, patients treated nonoperatively between 2000 and 2009 were invited for a sonographic follow-up examination. In group I 81 patients and in group II 89 patients were treated. An increase of male patients from 69 to 88 % was observed, comparing the two eras. While children treated in the earlier period were 8.8-years-old mean (range 1 to 15), the patients treated between 2000 and 2009 were older (mean 10.4 years, range 1 to 17). Between 1977 and 1999, 79 % of the patients were treated nonoperatively. This rate considerably increased to 94 % in the second era. Follow-up examination was performed with a mean age of 6 years (range 1 to 11 years) post-injury. In 79 % of the cases, the spleen healed without sonographic long-term sequelae. In the remaining 21 % of the patients, a scar formation could be demonstrated. CONCLUSION:We were able to confirm that the majority of children sustaining BSI can be safely treated conservatively.
journal_name
Eur J Pediatrjournal_title
European journal of pediatricsauthors
Singer G,Rieder S,Eberl R,Wegmann H,Hoellwarth MEdoi
10.1007/s00431-013-2022-7subject
Has Abstractpub_date
2013-09-01 00:00:00pages
1187-90issue
9eissn
0340-6199issn
1432-1076journal_volume
172pub_type
杂志文章abstract：:Achondroplasia, the most common form of chondrodysplasia, has been associated with mutations in the gene of the fibroblast growth factor receptor-3 (FGFR-3) on chromosome 4p. All 39 achondroplasia alleles studied so far carried point mutations which caused the same amino acid exchange, a substitution of glycine by arg...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF01954274
更新日期：1995-03-01 00:00:00
abstract：:To nine cystic fibrosis patients with chronic bronchopulmonary infection of severely damaged lungs invaded by Pseudomonas aeruginosa, eleven courses of prolonged tobramycin treatment (5 mg/kg/day) for four to 16 weeks were administered. Pulmonary symptoms improved and a better quality of life was achieved in all but o...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00441362
更新日期：1979-04-03 00:00:00
abstract：:Cerebral blood flow velocities (CBFV) were measured by the pulsed Doppler method in 41 infants of smoking mothers and in 59 apparently healthy control infants. Although gestational age, birth weight, and systolic blood pressure were lower in infants exposed to tobacco smoke prenatally, systolic (65 +/- 11 vs. 47 +/- 1...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF01956151
更新日期：1993-03-01 00:00:00
abstract：:This study was conducted to assess the clinical spectrum, management, and outcome of SARS-CoV-2-related multisystem inflammatory syndrome in children (MIS-C). We reviewed medical records of children with MIS-C diagnosis seen at the Children's Hospital of Michigan in Detroit between April and June 2020. Thirty-three ch...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-021-03935-1
更新日期：2021-01-16 00:00:00
abstract：UNLABELLED:The objective of this study was to study the experiences of parents of preterm infants who use social networking sites and the potential of such sites for gathering information and facilitating personal exchange. An anonymous self-reporting questionnaire was administered to parents of infants below 1,500 g b...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-013-2067-7
更新日期：2013-12-01 00:00:00
abstract：:CD3+4-8- double negative cells in peripheral blood lymphocytes were examined in 21 severely handicapped children divided into two groups according to serum IgG level. All children were bedridden and were taking multiple anticonvulsants and there were no apparent clinical differences between these two groups. Serum lev...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF01954738
更新日期：1994-12-01 00:00:00
abstract：:We report a 16-year-old girl who was diagnosed with acute leukaemia and a marked leucocytosis >200 × 109/L. She presented with marked hypophosphatemia, hypokalemia, acute renal failure and acute respiratory failure. These electrolytes disturbances may indicate rapid tumour genesis. These ominous findings required urge...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-017-2899-7
更新日期：2017-08-01 00:00:00
abstract：UNLABELLED:This retrospective study attempts to assess the size and growth pattern of the pulmonary artery about 1 year after neonatal arterial switch operation for simple transposition of the great arteries. Sixty-seven patients underwent cardiac catheterization, including catheterization of the right and left pulmona...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s004310050777
更新日期：1998-02-01 00:00:00
abstract：:Staphylococcus saprophyticus commonly causes urinary tract infection (UTI) in young women; in males it is found mainly in the elderly. In this study S. saprophyticus UTI occurred in 59 children (45 girls and 14 boys) below 16 years of age, of whom 20 were less than 13 years of age. The common presentation was dysuria ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02072520
更新日期：1993-01-01 00:00:00
abstract：:Purine nucleoside phosphorylase (PNP) deficiency is a rare combined immunodeficiency disorder presenting with clinically recurrent infections, failure to thrive, various neurological disorders, malignancies, and autoimmune diseases. Here, we report two sisters with a fatal course of PNP deficiency due to delay in diag...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-009-1029-6
更新日期：2010-03-01 00:00:00
abstract：UNLABELLED:Inflammation of the gastric and duodenal mucosa is the end result of an imbalance between mucosal defensive and aggressive factors. The degree of inflammation and imbalance between defensive and aggressive factors can then result in varying degrees of gastritis and/or frank mucosal ulceration. Gastritis and ...
journal_title：European journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s004310051142
更新日期：1999-07-01 00:00:00
abstract：UNLABELLED:The pattern and distribution of subcutaneous fat in term and preterm newborns has been assessed by skinfold thicknesses (ST), describing gender and gestational age variations. Weight, length and ST (triceps, biceps, subscapular and suprailiac) were measured in 4634 neonates (2445 males and 2189 females) aged...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-004-1468-z
更新日期：2004-08-01 00:00:00
abstract：: ...
journal_title：European journal of pediatrics
pub_type： 评论,信件
doi：10.1007/s00431-018-3252-5
更新日期：2019-01-01 00:00:00
abstract：:Pediatric palliative care (PPC) focuses on children and adolescents with life-limiting diseases. It may be initiated at various points of the disease trajectory, if possible early enough to support living with the best possible quality of life despite a limited lifespan. From birth to adolescence, children with a broa...
journal_title：European journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s00431-012-1710-z
更新日期：2013-02-01 00:00:00
abstract：UNLABELLED:The aim of this study was to provide growth and sexual maturation reference data for Turkish children living in The Netherlands. We also compared these references with the reference data of children of Dutch origin and with Turkish reference data collected in Turkey and elsewhere in Europe. Cross-sectional g...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-003-1292-x
更新日期：2003-11-01 00:00:00
abstract：:The Dubowitz syndrome is a rare, autosomal, recessively inherited disorder of intrauterine and postnatal growth retardation leading to microcephaly, moderate mental retardation and such characteristic facial anomalies as telecanthus, epicanthic folds, blepharophimosis, ptosis, broadening of the bridge and tip of the n...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00496039
更新日期：1986-04-01 00:00:00
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journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF01958950
更新日期：1992-02-01 00:00:00
abstract：UNLABELLED:This study was aimed to describe the epidemiology, clinical features, and prognosis of respiratory adenoviral infections among children in Suzhou, China. From 1 January 2006 to 31 December 2012, medical records of 474 hospitalized patients with respiratory adenovirus infection were reviewed retrospectively. ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-013-2188-z
更新日期：2014-04-01 00:00:00
abstract：UNLABELLED:Storage of human breast milk by freezing or refrigeration of milk with and without heating have been recommended. This can hardly be avoided because of the social circumstances of most mothers who are regularly separated from their infants because of work or schooling as well as the particular needs of some ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s004310000577
更新日期：2000-11-01 00:00:00
abstract：:The number of infants born preterm including extremely premature babies is rising worldwide, particularly in low- and middle-income countries, which challenge neonatologists and milk banks for the provision of the most adequate nutrition for successful infant's growth and development. The benefits of mother's own milk...
journal_title：European journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s00431-020-03887-y
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abstract：:Urinary tract infection (UTI) is a common cause of sepsis in infants. Premature infants hospitalized at a neonatal intensive care unit often have risk factors for infection. In this group, the risk of UTI is not clearly known, and guidelines for urine analysis are not unanimous. We aimed to identify the risk of UTI in...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-017-3030-9
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journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s004310100745
更新日期：2001-06-01 00:00:00
abstract：:Following ion-exchange chromatography and subsequent thin-layer chromatography, 3 peculiar oligosaccharide excretion patterns were distinguished in 3 patients with beta-galactosidase deficiency. Each patient differed clinically and it is proposed that this method may be of use in characterizing various forms of beta-g...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00496087
更新日期：1980-05-01 00:00:00
abstract：UNLABELLED:To study the developmental effects of prenatal exposure to opiates, a prospective follow up study of 34 drug-exposed (opiates and nicotine) and 42 reference infants (nicotine exposure only) was conducted from January 1992 to September 1995. At the time of delivery, 12 of 34 mothers used opiates without medic...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s004310050923
更新日期：1998-09-01 00:00:00
abstract：UNLABELLED:In this study, 144 consecutive percutaneous liver biopsies performed with a 1.6 mm Menghini needle, during a 2-year period were reviewed. All the children were aged under 15 years, 57 patients less than 1 year and 87 more than 1 year. All biopsies were adequate and the mean number of portal tracts examined w...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02079063
更新日期：1995-08-01 00:00:00
abstract：UNLABELLED:The aim of this study was to establish the correlations between the polymorphisms of the genes interleukin (IL)-6 572, 190, and 174 in obese children. We assessed 222 hospitalized children divided into two groups: group I (control) included 110 patients with normal nutritional status, and group II consisted ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-014-2315-5
更新日期：2014-10-01 00:00:00
abstract：:Vitamin K prophylaxis in infancy aims to prevent life-threatening vitamin K deficiency bleeding (VKDB). The Dutch prophylactic oral daily regimen was increased sixfold from 25 to 150 μg because of a high failure rate. To evaluate the efficacy of this new regimen, incidences of intracranial VKDB under both regimens wer...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-019-03391-y
更新日期：2019-07-01 00:00:00
abstract：:A male infant with transient citrullinemia is described. Initially, he was found to have hypertyrosinemia and hypermethioninemia upon routine neonatal screening for inborn errors of metabolism performed at 4 days of age and was revealed to have citrullinemia upon detailed examination of plasma amino acids. At 30 days ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00445674
更新日期：1983-10-01 00:00:00
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journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-016-2780-0
更新日期：2016-12-01 00:00:00
abstract：:Hypoparathyroidism is one of the recognized causes of late-onset neonatal hypocalcemia. Maternal hypercalcemic hyperparathyroidism has been shown to suppress fetal parathyroid glands, causing transient neonatal hypoparathyroidism. We report two siblings (6 years apart) with transient hypoparathyroidism presented with ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-007-0528-6
更新日期：2008-04-01 00:00:00
