Abstract：
:A severe shortage of good quality donor cornea is now an international crisis in public health. Alternatives for donor tissue need to be urgently developed to meet the increasing demand for corneal transplantation. Hydrogels have been widely used as scaffolds for corneal tissue regeneration due to their large water content, similar to that of native tissue. However, these hydrogel scaffolds lack the fibrous structure that functions as a load-bearing component in the native tissue, resulting in poor mechanical performance. This work shows that mechanical properties of compliant hydrogels can be substantially enhanced with electrospun nanofiber reinforcement. Electrospun gelatin nanofibers were infiltrated with alginate hydrogels, yielding transparent fiber-reinforced hydrogels. Without prior crosslinking, electrospun gelatin nanofibers improved the tensile elastic modulus of the hydrogels from 78±19 kPa to 450±100 kPa. Stiffer hydrogels, with elastic modulus of 820±210 kPa, were obtained by crosslinking the gelatin fibers with carbodiimide hydrochloride in ethanol before the infiltration process, but at the expense of transparency. The developed fiber-reinforced hydrogels show great promise as mechanically robust scaffolds for corneal tissue engineering applications.
journal_name
J Mech Behav Biomed Materauthors
Tonsomboon K,Oyen MLdoi
10.1016/j.jmbbm.2013.03.001subject
Has Abstractpub_date
2013-05-01 00:00:00pages
185-94eissn
1751-6161issn
1878-0180pii
S1751-6161(13)00079-9journal_volume
21pub_type
杂志文章abstract：:Breast implant durability and the mechanisms of rupture are important topics in the medical community, for patients, manufactures and regulatory medical agencies. After concerns about the Poly Implant Prosthesis (PIP) implants, the need for understanding the adverse outcomes and the failure mode to improve the breast ...
journal_title：Journal of the mechanical behavior of biomedical materials
pub_type： 杂志文章
doi：10.1016/j.jmbbm.2017.04.005
更新日期：2017-08-01 00:00:00
abstract：:In the present work, mechano-geometrical characterisations of skeletal muscle fibres in two different deformation states, namely, axial tension and axial compression, were realised. In both cases, cyclic and relaxation tests were performed. Additionally, the changes in the volume of the fibres during deformation were ...
journal_title：Journal of the mechanical behavior of biomedical materials
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更新日期：2020-10-01 00:00:00
abstract：:This aim of this study is to determine the elastoplastic properties of Ni-free Al3FeSi2 intermetallic coatings grown on medical stainless steel under different experimental conditions. Elastoplastic properties are defined by the plasticity index (PI), which correlates the hardness and the Young's modulus. Special emph...
journal_title：Journal of the mechanical behavior of biomedical materials
pub_type： 杂志文章
doi：10.1016/j.jmbbm.2015.02.018
更新日期：2015-06-01 00:00:00
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journal_title：Journal of the mechanical behavior of biomedical materials
pub_type： 杂志文章
doi：10.1016/j.jmbbm.2016.03.034
更新日期：2016-08-01 00:00:00
abstract：:The Zn-based alloys, alloyed with the elements of the 2nd group of the periodic table, are considered as potential biodegradable materials suitable for the fabrication of small orthopaedic implants or cardiovascular stents. Unfortunately, the as-cast Zn-based alloys do not fulfil the requirements for mechanical proper...
journal_title：Journal of the mechanical behavior of biomedical materials
pub_type： 杂志文章
doi：10.1016/j.jmbbm.2020.103796
更新日期：2020-08-01 00:00:00
abstract：:Hydrogels are promising materials for bioengineering applications, and are good model materials for the study of hydrated biological tissues. As these materials often have a structural function, the measurement of their mechanical properties is of fundamental importance. In the present study gelatin gels reinforced wi...
journal_title：Journal of the mechanical behavior of biomedical materials
pub_type： 杂志文章
doi：10.1016/j.jmbbm.2011.01.009
更新日期：2011-05-01 00:00:00
abstract：:With the emergence of new biomaterials and elastography imaging techniques, there is a need for innovative instruments dedicated to viscoelasticity measurements. In this work, we introduce a novel hyper-frequency viscoelastic spectroscopy (HFVS) technique dedicated to characterize soft media subjected to mid-to-very-h...
journal_title：Journal of the mechanical behavior of biomedical materials
pub_type： 杂志文章
doi：10.1016/j.jmbbm.2011.03.020
更新日期：2011-10-01 00:00:00
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journal_title：Journal of the mechanical behavior of biomedical materials
pub_type： 杂志文章
doi：10.1016/j.jmbbm.2018.04.013
更新日期：2018-07-01 00:00:00
abstract：:Skeletal abnormalities reported in humans and laboratory animals after spaceflight, include cancellous osteopenia, decreased cortical and cancellous bone formation, aberrant matrix ultrastructure, decreased mineralization and reduced bone strength. Although considerable effort has been made up to now to understand the...
journal_title：Journal of the mechanical behavior of biomedical materials
pub_type： 杂志文章
doi：10.1016/j.jmbbm.2008.06.004
更新日期：2009-04-01 00:00:00
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journal_title：Journal of the mechanical behavior of biomedical materials
pub_type： 杂志文章
doi：10.1016/j.jmbbm.2017.06.003
更新日期：2017-10-01 00:00:00
abstract：BACKGROUND:There are several factors that contribute to the failure of total ankle replacement (TAR). Aseptic loosening is one of the primary mechanisms of failure in TAR. Since a cross-linked ultrahigh molecular weight polyethylene (UHMWPE) is used as liner material, there is a need to quantify and develop methods to ...
journal_title：Journal of the mechanical behavior of biomedical materials
pub_type： 杂志文章
doi：10.1016/j.jmbbm.2014.12.010
更新日期：2015-04-01 00:00:00
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journal_title：Journal of the mechanical behavior of biomedical materials
pub_type： 杂志文章
doi：10.1016/j.jmbbm.2020.103698
更新日期：2020-04-01 00:00:00
abstract：:Nickel and carbides free Co-28Cr-6Mo alloy was fabricated by combination of mechanical alloying and warm pressing. The microstructure, mechanical properties, pin-on-disk dry sliding wear and corrosion behavior in simulated physiological solution were investigated. The produced Co-28Cr-6Mo alloy has elongated ultra-fin...
journal_title：Journal of the mechanical behavior of biomedical materials
pub_type： 杂志文章
doi：10.1016/j.jmbbm.2015.12.039
更新日期：2016-07-01 00:00:00
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journal_title：Journal of the mechanical behavior of biomedical materials
pub_type： 杂志文章
doi：10.1016/j.jmbbm.2015.09.001
更新日期：2016-05-01 00:00:00
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journal_title：Journal of the mechanical behavior of biomedical materials
pub_type： 杂志文章
doi：10.1016/j.jmbbm.2020.104209
更新日期：2021-02-01 00:00:00
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journal_title：Journal of the mechanical behavior of biomedical materials
pub_type： 杂志文章
doi：10.1016/j.jmbbm.2017.12.032
更新日期：2018-03-01 00:00:00
abstract：:This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the Editor-in-Chief. The authors have reused figures and text that have already appeared in their previous articles. Figure 4 duplicat...
journal_title：Journal of the mechanical behavior of biomedical materials
pub_type： 杂志文章,收录出版
doi：10.1016/j.jmbbm.2014.11.009
更新日期：2015-02-01 00:00:00
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journal_title：Journal of the mechanical behavior of biomedical materials
pub_type： 杂志文章
doi：10.1016/j.jmbbm.2018.10.021
更新日期：2019-02-01 00:00:00
abstract：:A mixture of water/carbon dioxide is a "green" perspective solvent from the viewpoint of biomedical applications. Clathrate hydrates are formed this solvent under certain conditions and a very interesting question is the impact of clathrates hydrates on the structure and properties of bovine pericardium, which is used...
journal_title：Journal of the mechanical behavior of biomedical materials
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doi：10.1016/j.jmbbm.2016.11.015
更新日期：2017-03-01 00:00:00
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journal_title：Journal of the mechanical behavior of biomedical materials
pub_type： 杂志文章
doi：10.1016/j.jmbbm.2015.07.003
更新日期：2015-11-01 00:00:00
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journal_title：Journal of the mechanical behavior of biomedical materials
pub_type： 杂志文章
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更新日期：2019-06-01 00:00:00
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journal_title：Journal of the mechanical behavior of biomedical materials
pub_type： 杂志文章
doi：10.1016/j.jmbbm.2016.05.010
更新日期：2016-09-01 00:00:00
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journal_title：Journal of the mechanical behavior of biomedical materials
pub_type： 杂志文章
doi：10.1016/j.jmbbm.2018.10.004
更新日期：2019-02-01 00:00:00
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journal_title：Journal of the mechanical behavior of biomedical materials
pub_type： 杂志文章
doi：10.1016/j.jmbbm.2020.104306
更新日期：2021-01-07 00:00:00
abstract：STATEMENT OF PROBLEM:The surface hardness and roughness of different glaze materials for denture base acrylic resins have not been well reported. PURPOSE:The purpose of the study was to measure the surfaces hardness, elastic modulus and surface roughness of 5 different light-polymerized glaze materials for poly methyl...
journal_title：Journal of the mechanical behavior of biomedical materials
pub_type： 杂志文章
doi：10.1016/j.jmbbm.2019.103601
更新日期：2020-03-01 00:00:00
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journal_title：Journal of the mechanical behavior of biomedical materials
pub_type： 杂志文章
doi：10.1016/j.jmbbm.2011.08.022
更新日期：2012-03-01 00:00:00
abstract：:Myocardial infarction (MI) is one of leading diseases to contribute to annual death rate of 5% in the world. In the past decades, significant work has been devoted to this subject. Biomechanics of infarcted left ventricle (LV) is associated with MI diagnosis, understanding of remodelling, MI micro-structure and biomec...
journal_title：Journal of the mechanical behavior of biomedical materials
pub_type： 杂志文章,评审
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更新日期：2020-03-01 00:00:00
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journal_title：Journal of the mechanical behavior of biomedical materials
pub_type： 杂志文章
doi：10.1016/j.jmbbm.2020.104067
更新日期：2020-12-01 00:00:00
abstract：:Calcium sulfate hemihydrate (CSH) was introduced into the mineralized collagen (nHAC) to prepare an injectable and self-setting in situ bone graft substitute. The mechanical properties of materials, which are dependant on the L/S ratio, the content of nHAC and setting accelerator, were discussed based on the satisfyin...
journal_title：Journal of the mechanical behavior of biomedical materials
pub_type： 杂志文章
doi：10.1016/j.jmbbm.2011.12.007
更新日期：2012-08-01 00:00:00
abstract：:The paper describes a highly space-resolved characterization of the surface mechanical properties of the posterior human corneal layer (Descemet's membrane). This has been accomplished with Atomic Force Microscopy (AFM) nano-indentation by using a probe with a sharp tip geometry. Results indicate that the contact with...
journal_title：Journal of the mechanical behavior of biomedical materials
pub_type： 杂志文章
doi：10.1016/j.jmbbm.2017.05.019
更新日期：2017-10-01 00:00:00
