Lifestyle factors, autoimmune disease and family history in prognosis of non-hodgkin lymphoma overall and subtypes.

Abstract:

:Lifestyle factors and medical history are known to influence risk of non-Hodgkin lymphoma (NHL). Whether these factors affect the prognosis of NHL, especially its subtypes, is unclear. To investigate this, the association between these factors and all-cause and lymphoma-related mortality was assessed in a population-based cohort of 1,523 Swedish NHL patients included in the Scandinavian Lymphoma Etiology study in 1999-2002. Participants contributed time from NHL diagnosis until death or October 1, 2010, with virtually complete follow-up through linkage to the Swedish Cause of Death Register. Hazard ratios (HR) and 95% confidence intervals (CI) were estimated using stratified and multivariable-adjusted Cox regression models. During a median follow-up of 8.8 years, 670 patients (44%) died, with the majority of deaths attributed to lymphoma (86%). Current versus never smoking at diagnosis was associated with increased rate of all-cause death for all NHL (HR = 1.5, 1.2-1.8) and diffuse large B-cell lymphoma (HR = 1.8, 1.2-2.7). Low educational level (HR = 1.3, 1.1-1.7, <9 vs. >12 years) and NHL risk-associated autoimmune disease (HR = 1.4, 1.0-1.8) were associated with death for all NHL combined. However, evidence of an association with lymphoma-related death was limited. Body mass index, recent sunbathing and family history of hematopoietic malignancy were not consistently associated with death after NHL or its specific subtypes. These results add to the evidence that cigarette smoking, socioeconomic status and certain autoimmune diseases affect survival after NHL. Further investigations are needed to determine how these factors should be incorporated into clinical prognostic assessment.

journal_name

Int J Cancer

authors

Simard JF,Baecklund F,Chang ET,Baecklund E,Hjalgrim H,-Olov Adami H,Glimelius B,Smedby KE

doi

10.1002/ijc.27944

subject

Has Abstract

pub_date

2013-06-01 00:00:00

pages

2659-66

issue

11

eissn

0020-7136

issn

1097-0215

journal_volume

132

pub_type

杂志文章
  • Expression and localization of human multidrug resistance protein (ABCC) family members in pancreatic carcinoma.

    abstract::Pancreatic ductal adenocarcinoma is among the top 10 causes of death from cancer in industrialized countries. In comparison with other gastrointestinal malignancies, pancreatic cancer is one of the tumors most resistant to chemotherapy. An important mechanism of tumor multidrug resistance is increased drug efflux medi...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.20831

    authors: König J,Hartel M,Nies AT,Martignoni ME,Guo J,Büchler MW,Friess H,Keppler D

    更新日期:2005-06-20 00:00:00

  • Somatostatin-reduced proliferation of murine aplastic carcinoma conditioned to diabetes.

    abstract::Murine mammary aplastic carcinoma, when it is passed from one alloxan-diabetic animal to another, after several passages becomes conditioned to hypoinsulinemia by secreting its own substance(s) immunologically cross-reactive with insulin (SICRI). Although not cytotoxic, the total daily dose of 2.5 mg of synthetic line...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.2910290614

    authors: Vuk-Pavlović S,Bozikov V,Pavelić K

    更新日期:1982-06-15 00:00:00

  • Tobacco smoking, chewing habits, alcohol drinking and the risk of head and neck cancer in Nepal.

    abstract::Although tobacco smoking, pan chewing and alcohol drinking are important risk factors for head and neck cancer (HNC), the HNC risks conferred by products available in Nepal for these habits are unknown. We assessed the associations of tobacco smoking, chewing habits, and alcohol drinking with HNC risk in Nepal. A case...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.32823

    authors: Chang CP,Siwakoti B,Sapkota A,Gautam DK,Lee YA,Monroe M,Hashibe M

    更新日期:2020-08-01 00:00:00

  • Cytolytic activity of circulating human monocytes on transformed and untransformed human fibroblasts.

    abstract::Monocytes from the peripheral blood of 10 normal adult human donors were tested for their cytolytic activity on untransformed or SV40-transformed, early passage, human fibroblasts. Two pairs of human fibroblast lines (2303 and SV40-2303, 2931 and SV40-2931) were used and lysis was assessed in terms of release of [3H]t...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.2910230106

    authors: Mantovani A,Tagliabue A,Dean JH,Jerrells TR,Herberman RB

    更新日期:1979-01-15 00:00:00

  • Tobacco and occupation as risk factors in bladder cancer: a case-control study in southern Belgium.

    abstract::A pilot case-control study on bladder cancer, with population-based controls matched for each of 74 cases, has been conducted in two industrial areas of Southern Belgium in order to analyze the influence of tobacco use and occupation. Observed bladder cancer risk for smokers is more than 5 times higher than that for n...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.2910390304

    authors: Schifflers E,Jamart J,Renard V

    更新日期:1987-03-15 00:00:00

  • By inhibiting PFKFB3, aspirin overcomes sorafenib resistance in hepatocellular carcinoma.

    abstract::Hepatocellular carcinoma (HCC) is one of the few cancers with a continuous increase in incidence and mortality. Drug resistance is a major problem in the treatment of HCC. In this study, two sorafenib-resistant HCC cell lines and a nude mouse subcutaneously tumor model were used to explore the possible mechanisms lead...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.31022

    authors: Li S,Dai W,Mo W,Li J,Feng J,Wu L,Liu T,Yu Q,Xu S,Wang W,Lu X,Zhang Q,Chen K,Xia Y,Lu J,Zhou Y,Fan X,Xu L,Guo C

    更新日期:2017-12-15 00:00:00

  • Synchronous multiple primary gastrointestinal cancer exhibits frequent microsatellite instability.

    abstract::Colorectal (CRC) and gastric cancers (GC), the most common gastrointestinal malignancies, have been known to develop occasionally in a same patient. Previous studies have focused on the etiology of patients with multiple primary gastric and colorectal cancer (MPGCC); however, the carcinogenic process of MPGCC remains ...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0215(20000601)86:5<678::aid-ijc

    authors: Ohtani H,Yashiro M,Onoda N,Nishioka N,Kato Y,Yamamoto S,Fukushima S,Hirakawa-Ys Chung K

    更新日期:2000-06-01 00:00:00

  • Effect of synthetic matrix-metalloproteinase inhibitors on invasive capacity and proliferation of human malignant gliomas in vitro.

    abstract::Glioma invasion into the surrounding brain tissue is still a major obstacle for any therapeutical approach. As in other solid tumors, matrix-metalloproteases (MMPs) have been suggested as being involved. The aim of this study was to evaluate whether the use of MMP inhibitors to target the protease-mediated invasion pr...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0215(19990301)80:5<764::aid-ijc

    authors: Tonn JC,Kerkau S,Hanke A,Bouterfa H,Mueller JG,Wagner S,Vince GH,Roosen K

    更新日期:1999-03-01 00:00:00

  • Overcoming evasive resistance from vascular endothelial growth factor a inhibition in sarcomas by genetic or pharmacologic targeting of hypoxia-inducible factor 1α.

    abstract::Increased levels of hypoxia and hypoxia-inducible factor 1α (HIF-1α) in human sarcomas correlate with tumor progression and radiation resistance. Prolonged antiangiogenic therapy of tumors not only delays tumor growth but may also increase hypoxia and HIF-1α activity. In our recent clinical trial, treatment with the v...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.27666

    authors: Kim YJ,Lee HJ,Kim TM,Eisinger-Mathason TS,Zhang AY,Schmidt B,Karl DL,Nakazawa MS,Park PJ,Simon MC,Yoon SS

    更新日期:2013-01-01 00:00:00

  • Frequent inactivation of SPARC by promoter hypermethylation in colon cancers.

    abstract::Epigenetic modification of gene expression plays an important role in the development of human cancers. The inactivation of SPARC through CpG island methylation was studied in colon cancers using oligonucleotide microarray analysis and methylation specific PCR (MSP). Gene expression of 7 colon cancer cell lines was ev...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.22706

    authors: Yang E,Kang HJ,Koh KH,Rhee H,Kim NK,Kim H

    更新日期:2007-08-01 00:00:00

  • Lifetime and baseline alcohol intake and risk of cancer of the upper aero-digestive tract in the European Prospective Investigation into Cancer and Nutrition (EPIC) study.

    abstract::Recent alcohol consumption is an established risk factor for squamous cell carcinoma (SCC) of the upper aero-digestive tract. In contrast, the role of lifetime exposure to alcohol with regard to risk of SCC is not well established. Historical data on alcohol use are available in 271,253 participants of the European Pr...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.24393

    authors: Weikert C,Dietrich T,Boeing H,Bergmann MM,Boutron-Ruault MC,Clavel-Chapelon F,Allen N,Key T,Lund E,Olsen A,Tjønneland A,Overvad K,Rohrmann S,Linseisen J,Pischon T,Trichopoulou A,Weinehall L,Johansson I,Sánchez MJ,Ag

    更新日期:2009-07-15 00:00:00

  • Infectious DNA recovered from avian tumor-virus-producing cells.

    abstract::A single treatment of chick embryo fibroblasts with DNA recovered from chick embryo fibroblasts productively infected and transformed with four different strains of RSV, or productively infected with two different strains of RAV, resulted in virus production and cell transformation (in the case of RSV) two or three p...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.2910150109

    authors: Vigier P,Montagnier L

    更新日期:1975-01-15 00:00:00

  • Postdiagnosis weight change is associated with poorer survival in breast cancer survivors: A prospective population-based patient cohort study.

    abstract::More women are surviving after breast cancer due to early detection and modern treatment strategies. Body weight also influences survival. We aimed to characterize associations between postdiagnosis weight change and prognosis in postmenopausal long-term breast cancer survivors. We used data from a prospective populat...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.33181

    authors: Jung AY,Hüsing A,Behrens S,Krzykalla J,Obi N,Becher H,Chang-Claude J

    更新日期:2021-01-01 00:00:00

  • Modulation of intra-epithelial expansion of human T24 bladder-carcinoma cells in murine urothelium by growth factors and extracellular-matrix components.

    abstract::The high recurrence rate of bladder cancer is probably due to an efficient repopulation of the bladder by residual transformed cells after resection of the tumour. However, the regenerating capacity of the normal urothelial cells is very high. To study the balance between regenerating normal urothelium and out-growth ...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.2910600523

    authors: Rebel JM,Thijssen CD,Vermey M,Zwarthoff EC,Van der Kwast TH

    更新日期:1995-03-03 00:00:00

  • In vivo efficacy of the recombinant anti-CD64 immunotoxin H22(scFv)-ETA' in a human acute myeloid leukemia xenograft tumor model.

    abstract::Target-specific acute myeloid leukemia (AML) immunotherapy requires selective cell-surface antigens on AML blast cells. CD64 is a promising candidate antigen because it is abundantly expressed on monocytoid differentiated AML subtypes. In previous studies, a chemically linked full-length anti-CD64 immunotoxin based on...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.25766

    authors: Tur MK,Huhn M,Jost E,Thepen T,Brümmendorf TH,Barth S

    更新日期:2011-09-01 00:00:00

  • Serum endostatin levels correlate with enhanced extracellular matrix degradation and poor patients' prognosis in bladder cancer.

    abstract::Endostatin, the proteolytic fragment of collagen XVIII, is an inhibitor of angiogenesis and tumor growth. Interestingly, elevated circulating endostatin levels have been found to correlate with poor patients' prognosis in several cancers. The aim of this study was to assess the prognostic value of endostatin in bladde...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.26343

    authors: Szarvas T,László V,Vom Dorp F,Reis H,Szendröi A,Romics I,Tilki D,Rübben H,Ergün S

    更新日期:2012-06-15 00:00:00

  • The spectrum of malignancies in HIV-infected patients in 2006 in France: the ONCOVIH study.

    abstract::Since no large descriptive studies of incident cancers in HIV-infected patients are available in France, the nationwide cross-sectional ONCOVIH study aimed to prospectively report new malignancies diagnosed in HIV-infected patients in cancer centers and HIV/AIDS centers. We estimated the number of cancers in France fo...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.25903

    authors: Lanoy E,Spano JP,Bonnet F,Guiguet M,Boué F,Cadranel J,Carcelain G,Couderc LJ,Frange P,Girard PM,Oksenhendler E,Poizot-Martin I,Semaille C,Agut H,Katlama C,Costagliola D,ONCOVIH study group.

    更新日期:2011-07-15 00:00:00

  • Progression to androgen-independent LNCaP human prostate tumors: cellular and molecular alterations.

    abstract::Lethal phenotypes of human prostate cancer are characterized by progression to androgen-independence and metastasis. For want of a clinically relevant animal model, mechanisms behind this progression remain unclear. Our study used an in vivo model of androgen-sensitive LNCaP human prostate cancer cell xenografts in ma...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.20206

    authors: Zhou JR,Yu L,Zerbini LF,Libermann TA,Blackburn GL

    更新日期:2004-07-20 00:00:00

  • Anti-tumor activity of mycophenolate mofetil against human and mouse tumors in vivo.

    abstract::Cultured tumor cell lines, tumor xenografts grown in athymic nude mice, and a murine experimental metastasis model were used to assess the in vitro and in vivo anti-tumor activity of the potent IMP dehydrogenase (IMPDH) inhibitor, mycophenolic acid (MPA), and its morpholinoethyl ester pro-drug, mycophenolate mofetil (...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.2910570421

    authors: Tressler RJ,Garvin LJ,Slate DL

    更新日期:1994-05-15 00:00:00

  • Downregulation of SERPINB13 expression in head and neck squamous cell carcinomas associates with poor clinical outcome.

    abstract::Tumorigenesis of head and neck squamous cell carcinomas (HNSCC) is associated with various genetic changes such as loss of heterozygosity (LOH) on human chromosome 18q21. This chromosomal region maps a gene cluster coding for a family of intracellular serine protease inhibitors (serpins), including SERPINB13. As SERPI...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.24507

    authors: de Koning PJ,Bovenschen N,Leusink FK,Broekhuizen R,Quadir R,van Gemert JT,Hordijk GJ,Chang WS,van der Tweel I,Tilanus MG,Kummer JA

    更新日期:2009-10-01 00:00:00

  • Adoptive transfer of human natural killer cells in mice with severe combined immunodeficiency inhibits growth of Hsp70-expressing tumors.

    abstract::In vitro, tumor-selective Hsp70 plasma membrane localization correlates with increased sensitivity to lysis mediated by a subpopulation of human natural killer (NK) cells that adhere to plastic following cytokine stimulation. In the present study, we analyzed the capacity of adoptively transferred human NK cells in SC...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0215(20001201)88:5<791::aid-ijc17>3.0

    authors: Multhoff G,Pfister K,Botzler C,Jordan A,Scholz R,Schmetzer H,Burgstahler R,Hiddemann W

    更新日期:2000-12-01 00:00:00

  • Isothiocyanates, glutathione S-transferase M1 and T1 polymorphisms and gastric cancer risk: a prospective study of men in Shanghai, China.

    abstract::Isothiocyanates (ITC) in cruciferous vegetables may be chemopreventive against gastric cancer development. Glutathione S-transferases (GSTs) may modify the chemopreventive effect of ITC. The relationship between urinary total ITC and risk of gastric cancer was prospectively examined. Between 1986 and 1989, 18,244 midd...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.24583

    authors: Moy KA,Yuan JM,Chung FL,Wang XL,Van Den Berg D,Wang R,Gao YT,Yu MC

    更新日期:2009-12-01 00:00:00

  • Intracystic epidermal growth factor level is predictive of breast-cancer risk in women with gross cystic disease of the breast.

    abstract::Women affected by gross cystic disease of the breast have an increased risk of breast cancer. We report here the incidence of breast cancer by cyst type and intracystic epidermal growth factor (EGF) concentration. Our retrospective study included 504 women who had at least 1 cyst aspiration between 1985 and 1993. Cyst...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0215(20010720)95:4<260::aid-ijc1044>3

    authors: Boccardo F,Marenghi C,Ghione G,Pepe A,Parodi S,Rubagotti A

    更新日期:2001-07-20 00:00:00

  • The bidirectional interaction of the gut microbiome and the innate immune system: Implications for chemotherapy-induced gastrointestinal toxicity.

    abstract::Chemotherapy-induced gastrointestinal toxicity (CIGT) occurs in up to 80% of all patients undergoing cancer treatment, and leads to symptoms such as diarrhoea, abdominal bleeding and pain. There is currently limited understanding of how to predict an individual patient's risk of CIGT. It is believed the gut microbiome...

    journal_title:International journal of cancer

    pub_type: 杂志文章,评审

    doi:10.1002/ijc.31836

    authors: Secombe KR,Coller JK,Gibson RJ,Wardill HR,Bowen JM

    更新日期:2019-05-15 00:00:00

  • Hemizygous or homozygous deletion of the chromosomal region containing the p16INK4a gene is associated with amplification of the EGF receptor gene in glioblastomas.

    abstract::The p16INK4a gene product acts as a negative regulator of the cell cycle by binding to cyclin-dependent kinases (CDKs) 4 and 6, thereby inhibiting the formation of an active CDK/cyclin D complex. Deletion of the p16 locus has been observed in tumor cell lines and, less frequently, in primary human neoplasms. We analyz...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0215(19970926)73:1<57::aid-ijc1

    authors: Hegi ME,zur Hausen A,Rüedi D,Malin G,Kleihues P

    更新日期:1997-09-26 00:00:00

  • Comparison of 131I-labelled anti-episialin 139H2 with cisplatin, cyclophosphamide or external-beam radiation for anti-tumor efficacy in human ovarian cancer xenografts.

    abstract::Three human ovarian cancer xenografts of different origin and grown s.c. in nude mice as well-established tumors were studied for their sensitivity to cisplatin (CDDP), cyclophosphamide (CTX), 131I-labelled anti-episialin monoclonal antibody (MAb) 139H2, or external-beam radiotherapy. The maximum tolerated dose of CDD...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.2910510120

    authors: Molthoff CF,Pinedo HM,Schlüper HM,Rutgers DH,Boven E

    更新日期:1992-04-22 00:00:00

  • Imbalances of chemokines, chemokine receptors and cytokines in Hodgkin lymphoma: classical Hodgkin lymphoma vs. Hodgkin-like ATLL.

    abstract::Classical Hodgkin lymphoma (HL) is characterized by the presence of Hodgkin and Reed-Sternberg cells (H&RS) and a prominent lymphocytic infiltration. We previously reported Hodgkin-like adult T-cell leukemia/lymphoma (HL-like ATLL) (new WHO classification). Various CXC and CC chemokines are expressed on H&RS cells and...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.11301

    authors: Ohshima K,Karube K,Hamasaki M,Suefuji H,Tutiya T,Yamaguchi T,Suzumiya J,Kikuchi M

    更新日期:2003-09-20 00:00:00

  • An immunoregulatory factor associated with spleen cells from tumor-bearing animals. I. Effect on tumor growth and antibody production.

    abstract::An immunopotentiating factor associated with spleen cells of C57BL/6J mice bearing the 3LL tumor is described. Supernatants of cultured spleen cells from tumor-bearing mice (TBM) augmented the generation of both 19S and 7S antibody-producing cells, when injected with sheep erythrocytes into syngeneic C57BL/6J mice. Th...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.2910220416

    authors: Isakov N,Segal S,Hollander N,Feldman M

    更新日期:1978-10-15 00:00:00

  • HLA-B alleles, high-risk HPV infection and risk for cervical neoplasia in southern Chinese women.

    abstract::A population-based study was conducted on 256 southern Chinese with cervical intraepithelial neoplasia grade III (CIN III) or invasive cervical cancer (ICC) and on 258 controls to examine the associations between HLA-B alleles, infection with high-risk human papillomaviruses (HPVs) and the development of cervical neop...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.21528

    authors: Chan PK,Cheung JL,Cheung TH,Lin CK,Tam AO,Chan DP,Zhou DX,Lo KW,Yim SF,Siu SS

    更新日期:2006-03-15 00:00:00

  • Detergent extraction and characterization of tumor hemolytic factor from plasma membranes of oncogene transformed fibroblasts.

    abstract::Cancer cells have the capacity to lyse erythrocytes by a cell-contact-requiring phenomenon. Subcellular fractionation procedures have revealed that the hemolytic principle resides in the cancer cell plasma membrane. In this study we report the detergent extraction of a potent hemolytic factor from the plasma membranes...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.2910470217

    authors: Zucker S,DiMassimo BI,Lysik RM,Vuaridel-Bonanomi E

    更新日期:1991-01-21 00:00:00