Lifestyle factors, autoimmune disease and family history in prognosis of non-hodgkin lymphoma overall and subtypes.

Abstract:

:Lifestyle factors and medical history are known to influence risk of non-Hodgkin lymphoma (NHL). Whether these factors affect the prognosis of NHL, especially its subtypes, is unclear. To investigate this, the association between these factors and all-cause and lymphoma-related mortality was assessed in a population-based cohort of 1,523 Swedish NHL patients included in the Scandinavian Lymphoma Etiology study in 1999-2002. Participants contributed time from NHL diagnosis until death or October 1, 2010, with virtually complete follow-up through linkage to the Swedish Cause of Death Register. Hazard ratios (HR) and 95% confidence intervals (CI) were estimated using stratified and multivariable-adjusted Cox regression models. During a median follow-up of 8.8 years, 670 patients (44%) died, with the majority of deaths attributed to lymphoma (86%). Current versus never smoking at diagnosis was associated with increased rate of all-cause death for all NHL (HR = 1.5, 1.2-1.8) and diffuse large B-cell lymphoma (HR = 1.8, 1.2-2.7). Low educational level (HR = 1.3, 1.1-1.7, <9 vs. >12 years) and NHL risk-associated autoimmune disease (HR = 1.4, 1.0-1.8) were associated with death for all NHL combined. However, evidence of an association with lymphoma-related death was limited. Body mass index, recent sunbathing and family history of hematopoietic malignancy were not consistently associated with death after NHL or its specific subtypes. These results add to the evidence that cigarette smoking, socioeconomic status and certain autoimmune diseases affect survival after NHL. Further investigations are needed to determine how these factors should be incorporated into clinical prognostic assessment.

journal_name

Int J Cancer

authors

Simard JF,Baecklund F,Chang ET,Baecklund E,Hjalgrim H,-Olov Adami H,Glimelius B,Smedby KE

doi

10.1002/ijc.27944

subject

Has Abstract

pub_date

2013-06-01 00:00:00

pages

2659-66

issue

11

eissn

0020-7136

issn

1097-0215

journal_volume

132

pub_type

杂志文章
  • Positive correlation between p27Kip1 expression and progression of human esophageal squamous cell carcinoma.

    abstract::p27Kip1, one of the cyclin-dependent kinase (CDK) inhibitors (CDKIs), blocks progression from G1 to S phase by binding cyclin D1-CDK4 and/or cyclin E-CDK2 and inhibiting their activities. Reflecting the function of p27 as a CDKI in vitro, a reduced expression of protein p27 has recently been reported to be associated ...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0215(19980821)79:4<439::aid-ijc

    authors: Anayama T,Furihata M,Ishikawa T,Ohtsuki Y,Ogoshi S

    更新日期:1998-08-21 00:00:00

  • ALDH1A1 in patient-derived bladder cancer spheroids activates retinoic acid signaling leading to TUBB3 overexpression and tumor progression.

    abstract::Acquired chemoresistance is a critical issue for advanced bladder cancer patients during long-term treatment. Recent studies reveal that a fraction of tumor cells with enhanced tumor-initiating potential, or cancer stem-like cells (CSCs), may particularly contribute to acquired chemoresistance and recurrence. Thus, CS...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.32505

    authors: Namekawa T,Ikeda K,Horie-Inoue K,Suzuki T,Okamoto K,Ichikawa T,Yano A,Kawakami S,Inoue S

    更新日期:2020-02-15 00:00:00

  • Decreased expression of phosphorylated JNK in breast infiltrating ductal carcinoma is associated with a better overall survival.

    abstract::Phosphorylation/activation of c-jun NH2-terminal kinase (JNK) has an ambivalent role, pro-proliferation or antiproliferation, in human cancers, which is determined by different cell types and by its crosstalk with other kinases. So far, the role of phosphorylated JNK (p-JNK) in breast cancer is mostly undefined. In th...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.21707

    authors: Yeh YT,Hou MF,Chung YF,Chen YJ,Yang SF,Chen DC,Su JH,Yuan SS

    更新日期:2006-06-01 00:00:00

  • Increased incidence of mouse mammary tumor virus-related antigen in Tunisian patients with breast cancer.

    abstract::Biopsies obtained from 74 Tunisian women with breast cancer (33 cases), benign breast disease (17 cases), and cervical cancer (24 cases) were assayed for the presence of an antigen cross-reacting with gp52 of the mouse mammary tumor virus (MMTV) in order to determine the frequency and possible prognostic significance ...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.2910330305

    authors: Levine PH,Mesa-Tejada R,Keydar I,Tabbane F,Spiegelman S,Mourali N

    更新日期:1984-03-15 00:00:00

  • Steady state levels of transforming growth factor-beta1 and -beta2 mRNA and protein expression are elevated in colonic tumors in vivo irrespective of dietary lipids intervention.

    abstract::Colonic tumors of human origin produce abundant transforming growth factor (TGF)-beta suggesting that TGF-beta is critical to their growth. Dietary lipids regulate a number of growth factors including TGF-beta. Whether elevated TGF-beta levels are consistently expressed in colonic tumors irrespective of the environmen...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.10522

    authors: Raju J,McCarthy B,Bird RP

    更新日期:2002-08-20 00:00:00

  • Anti-retrovirus activity of 9-(2-phosphonylmethoxyethyl)adenine (PMEA) in vivo increases when it is less frequently administered.

    abstract::Different treatment schedules have been investigated when evaluating the inhibitory effect of 9-(2-phosphonylmethoxyethyl)adenine (PMEA) and 3'-azido-2',3'-dideoxythymidine (AZT) on the replication of human immunodeficiency virus type I (HIV-I) in MT-4 cells, transformation of C3H/3T3 cells by Moloney murine sarcoma v...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.2910460233

    authors: Balzarini J,Naesens L,De Clercq E

    更新日期:1990-08-15 00:00:00

  • In vivo growth inhibition of L1210 leukemia by 4-amidinoindan-1-one 2'-amidinohydrazone (CGP 48664A), a new inhibitor of S-adenosylmethionine decarboxylase.

    abstract::We studied the in vivo growth-inhibitory effect of the new S-adenosylmethionine decarboxylase inhibitor 4-amidinoindan-1-one 2'-amidinohydrazone (CGP 48664A). L1210-bearing DBA-2 mice were treated with increasing CGP 48664A doses from 1 day after i.p. L1210 cell inoculation. Treatment was continued for 4 days, after w...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.2910610212

    authors: Dorhout B,Te Velde RJ,Ferwerda H,Kingma AW,De Hoog E,Muskiet FA

    更新日期:1995-04-10 00:00:00

  • Fractional allelic imbalance in human breast cancer increases with tetraploidization and chromosome loss.

    abstract::We have previously reported a complete allelotype study of 86 primary breast carcinomas, in which each non-acrocentric chromosome arm was studied with at least one polymorphic DNA-marker for the presence of allelic imbalance (AI, allelic loss or allelic gain) in the tumor. Here we report the statistical analysis of th...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.2910500408

    authors: Cornelisse CJ,Kuipers-Dijkshoorn N,van Vliet M,Hermans J,Devilee P

    更新日期:1992-02-20 00:00:00

  • Transcription of biliary glycoprotein I gene in malignant and non-malignant human liver tissues.

    abstract::Biliary glycoprotein I (BGP I) is a member of carcinoembryonic antigen (CEA) gene family consisting of at least 11 related genes. The transcription of BGP I gene was analysed in malignant and non-malignant human liver tissues with a 396-bp 3'-untranslated region probe from a cDNA clone 4-13 which was newly isolated fr...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.2910450516

    authors: Hinoda Y,Imai K,Nakagawa N,Ibayashi Y,Nakano T,Paxton RJ,Shively JE,Yachi A

    更新日期:1990-05-15 00:00:00

  • Mitotic activity, apoptosis and TRPM-2 mRNA expression in DMBA-induced rat mammary carcinoma treated with anti-estrogen toremifene.

    abstract::Anti-estrogen toremifene inhibits growth of the 7,12-dimethylbenz(a)anthracene(DMBA)-induced rat mammary carcinoma. The changes in proliferation and cell death were studied in detail. Proliferation was measured by counting mitotic figures in histologic sections, expressed by volume-corrected mitotic index (M/V INDEX)....

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.2910550429

    authors: Huovinen R,Wärri A,Collan Y

    更新日期:1993-10-21 00:00:00

  • Epigenetic silencing of SFRP1 and SFRP5 by hepatitis B virus X protein enhances hepatoma cell tumorigenicity through Wnt signaling pathway.

    abstract::Secreted frizzled-related proteins (SFRPs) are antagonists of the Wnt signaling pathway whose epigenetic downregulation have been shown to be involved in hepatocarcinogenesis. However, dysregulation of SFRPs induced by hepatitis B virus (HBV) X protein (HBx) has never been studied in HBV-related hepatocellular carcino...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.28697

    authors: Xie Q,Chen L,Shan X,Shan X,Tang J,Zhou F,Chen Q,Quan H,Nie D,Zhang W,Huang AL,Tang N

    更新日期:2014-08-01 00:00:00

  • An immunohistological study of leukocyte localization in benign and malignant breast tissue.

    abstract::Using morphometric and immunohistological techniques, we investigated the distribution of T lymphocytes and subsets, B lymphocytes, macrophages and plasma cells in sections of human breast tissue. In normal lobules and ducts, leukocytes were found in greater density in the epithelium than in the stroma. The intra-epit...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.2910360404

    authors: Lwin KY,Zuccarini O,Sloane JP,Beverley PC

    更新日期:1985-10-15 00:00:00

  • Reverse transcription-polymerase chain reaction assay for multiple mRNA markers in the detection of breast cancer metastases in sentinel lymph nodes.

    abstract::The identification of specific tumor mRNA markers by reverse transcription-polymerase chain reaction might be a valuable diagnostic adjunct for the detection of breast cancer metastases in axillary sentinel lymph nodes (SLNs). In this study we have compared the diagnostic accuracy of an extensive histopathologic exami...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0215(20010920)95:5<307::aid-ijc0153>3

    authors: Manzotti M,Dell'Orto P,Maisonneuve P,Zurrida S,Mazzarol G,Viale G

    更新日期:2001-09-20 00:00:00

  • Hormone replacement therapy and oral contraceptives and risk of oesophageal adenocarcinoma: a systematic review and meta-analysis.

    abstract::There is an unexplained strong male predominance in the aetiology of oesophageal adenocarcinoma (OAC). The hypothesis that oestrogens are protective, deserves attention. A potential protective influence of exogenous oestrogen exposure, that is, hormone replacement therapy (HRT) and oral contraceptives (OC) has been ad...

    journal_title:International journal of cancer

    pub_type: 杂志文章,meta分析,评审

    doi:10.1002/ijc.28869

    authors: Lagergren K,Lagergren J,Brusselaers N

    更新日期:2014-11-01 00:00:00

  • Site distribution of cutaneous melanoma in Queensland.

    abstract::The age-adjusted incidence rates of cutaneous melanoma in Queensland in 1987 have been analysed for 16 anatomic sites, taking into account their surface areas. In men, the incidence of invasive melanoma on the ears, a chronically sun-exposed site, was extraordinarily high with annual rates of over 200 per 10(5) units ...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.2910530210

    authors: Green A,MacLennan R,Youl P,Martin N

    更新日期:1993-01-21 00:00:00

  • Activation of the precursor of gelatinase A/72 kDa type IV collagenase/MMP-2 in lung carcinomas correlates with the expression of membrane-type matrix metalloproteinase (MT-MMP) and with lymph node metastasis.

    abstract::We have identified a novel membrane-type matrix metalloproteinase (MT-MMP) expressed on the cell surface and inducing activation of pro-gelatinase A in vitro. In this study, we further examined the possibility that MT-MMP is the activator of pro-gelatinase A in tumors as well as in vitro. Expression of MT-MMP mRNA was...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.2910640513

    authors: Tokuraku M,Sato H,Murakami S,Okada Y,Watanabe Y,Seiki M

    更新日期:1995-10-20 00:00:00

  • Risk of somatic diseases in offspring of survivors with childhood or adolescent central nervous system tumor in Sweden.

    abstract::With the improvement of treatments, a growing number of survivors with childhood or adolescent central nervous system (CNS) tumor are parenting their own children. We aimed to explore the risk of somatic diseases among children of these survivors compared to population controls. Children of survivors with CNS tumor be...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.33394

    authors: Huang W,Sundquist K,Sundquist J,Ji J

    更新日期:2020-11-13 00:00:00

  • A prospective study on the natural course of low-grade squamous intraepithelial lesions and the presence of HPV16 E2-, E6- and E7-specific T-cell responses.

    abstract::This study investigates the clinical course of low grade squamous intraepithelial lesions (LSIL), HPV status and HPV16-specific immune response in a large prospective study of 125 women with LSIL followed cytologically, virologically and histologically. Women with low-grade abnormal smears were recruited and followed-...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.24804

    authors: Woo YL,van den Hende M,Sterling JC,Coleman N,Crawford RA,Kwappenberg KM,Stanley MA,van der Burg SH

    更新日期:2010-01-01 00:00:00

  • The prevalence and concordance of human papillomavirus infection in different anogenital sites among men and women in Liuzhou, China: A population-based study.

    abstract::Human papillomavirus (HPV) infection is the pathogenesis of anogenital cancers and genital warts in both men and women, whereas there is a scarcity of large studies focused on HPV prevalence in different anogenital sites of both sexes in the same population. From May to July 2014, 2,309 men and 2,378 women aged 18-55 ...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.31128

    authors: Wei F,Li M,Wu X,Yin K,Lan J,Sheng W,Guo M,Huang S,Wang Y,Li Y,Li R,Su Y,Wu T,Zhang J,Xia N

    更新日期:2018-03-15 00:00:00

  • Effect of vesicle size and lipid composition on the in vivo tumor selectivity and toxicity of the non-cross-resistant anthracycline annamycin incorporated in liposomes.

    abstract::Annamycin (Ann) is a non-cross-resistant lipophilic anthracycline antiobiotic optimally suited for liposome delivery. We studied how vesicle size and presence of phospholipids with a high phase transition temperature and monosialoganglioside (GM I) in the liposome bilayers affect the pharmacokinetics, tumor selectivit...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.2910610513

    authors: Zou Y,Ling YH,Reddy S,Priebe W,Perez-Soler R

    更新日期:1995-05-29 00:00:00

  • Head and neck tumor sites differ in prevalence and spectrum of p53 alterations but these have limited prognostic value.

    abstract::The tumor site is a strong clinical factor in head and neck squamous cell carcinoma (HNSCC). To clarify the biologic and clinical role of p53 alterations in HNSCC, we have examined the prevalence and the nature of p53 alterations in a large cohort of tumors from the different sites. For immunohistochemical analysis of...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.11698

    authors: Bosch FX,Ritter D,Enders C,Flechtenmacher C,Abel U,Dietz A,Hergenhahn M,Weidauer H

    更新日期:2004-09-10 00:00:00

  • Effect of age at inoculation of asbestos on occurrence of mesotheliomas in rats.

    abstract::An experiment in which rats were injected intrapleurally with asbestos, the injection taking place at an age of either 2 or 10 months, is reported. In the former group 19 out of 48 rats developed a mesothelioma compared with 17 out of 90 in the latter group. However, by considering the two groups at equal times after ...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.2910170410

    authors: Berry G,Wagner JC

    更新日期:1976-04-15 00:00:00

  • Modification of the effect of C. parvum on macrophage activity and tumour growth by X-irradiation.

    abstract::The radiosensitivity of three forms of response to injection of C. parvum in mice has been investigated. The increase in phagocytin index evoked by IP or IV injection of 0.7 mg C. parvum (but not that evoked by 1.4 mg) was reduced but not abolished in mice given 350-500 rad whole-body irradiation 4 days before C. parv...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.2910170515

    authors: Woodruff MF,Ghaffar A,Whitehead VL

    更新日期:1976-05-15 00:00:00

  • Distribution of the transferrin receptor in normal human fibroblasts and fibrosarcoma cells.

    abstract::Transferrin is required for proliferation of most cells in culture. This effect is presumably mediated by the binding of transferrin to its receptor, a surface glycoprotein which is preferentially expressed by actively growing cells. Here we show that normal human fibroblasts cultured in serum, and other media contain...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.2910310118

    authors: Ekblom P,Thesleff I,Lehto VP,Virtanen I

    更新日期:1983-01-15 00:00:00

  • TOB suppresses breast cancer tumorigenesis.

    abstract::Transducer of ErbB-2 (TOB) is a member of the TOB/Btg gene family. A role for TOB in the suppression of human tumorigenesis has been proposed, based on the observations that TOB-knockout mice spontaneously form tumors and TOB expression is lost in human lung and thyroid cancers. However, the role of TOB in human breas...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.24490

    authors: O'Malley S,Su H,Zhang T,Ng C,Ge H,Tang CK

    更新日期:2009-10-15 00:00:00

  • Growth of Hodgkin cell lines in severely combined immunodeficient mice.

    abstract::No animal model exists for the in vivo growth of Hodgkin's-lymphoma-derived cells. Neither unmanipulated Hodgkin's-disease(HD)-derived cell lines nor primary biopsy tissue could be grown in nude mice. Since the severe combined immunodeficient (SCID) mouse has been reported to be a better recipient for transplanted hum...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.2910520610

    authors: von Kalle C,Wolf J,Becker A,Sckaer A,Munck M,Engert A,Kapp U,Fonatsch C,Komitowski D,Feaux de Lacroix W

    更新日期:1992-12-02 00:00:00

  • Protein kinase B modulates the sensitivity of human neuroblastoma cells to insulin-like growth factor receptor inhibition.

    abstract::The potential of the novel insulin-like growth factor receptor (IGF-IR) inhibitor NVP-AEW541 as an antiproliferative agent in human neuroblastoma was investigated. Proliferation of a panel of neuroblastoma cell lines was inhibited by NVP-AEW541 with IC(50) values ranging from 0.15 to 5 microM. Experiments using an IGF...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.22126

    authors: Guerreiro AS,Boller D,Shalaby T,Grotzer MA,Arcaro A

    更新日期:2006-12-01 00:00:00

  • Novel senescence associated gene, YPEL3, is repressed by estrogen in ER+ mammary tumor cells and required for tamoxifen-induced cellular senescence.

    abstract::Estrogen signaling plays an important role in breast carcinogenesis. An increased understanding of estrogen gene targets and their effects will allow for more directed and effective therapies for individuals with breast cancer, particularly those with estrogen receptor positive tumors resistant to tamoxifen therapy. H...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.26239

    authors: Tuttle R,Miller KR,Maiorano JN,Termuhlen PM,Gao Y,Berberich SJ

    更新日期:2012-05-15 00:00:00

  • Spontaneous in vitro malignant transformation in a xeroderma pigmentosum fibroblast line.

    abstract::This paper deals with a spontaneous malignant transformation in one of our XP fibroblast lines. This cell line, designated XP29MA, was derived from a 14-year-old boy who did not show skin tumors or precancerous alterations either at the time of clinical examination or when the biopsy was taken. We have compared the fo...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.2910310603

    authors: Thielmann HW,Fischer E,Dzarlieva RT,Komitowski D,Popanda O,Edler L

    更新日期:1983-06-15 00:00:00

  • Characterization of EBV-carrying B-cell populations in healthy seropositive individuals with regard to density, release of transforming virus and spontaneous outgrowth.

    abstract::Peripheral or tonsil lymphocyte populations of EBV-seropositive donors give rise to EBV-carrying LCLs upon in vitro explantation. Such lines can arise either by a 2-step mechanism, namely release of virus from some of the explanted cells followed by infection of previously uninfected B cells, or by direct outgrowth of...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.2910390411

    authors: Lewin N,Aman P,Masucci MG,Klein E,Klein G,Oberg B,Strander H,Henle W,Henle G

    更新日期:1987-04-15 00:00:00