Effects of estrogen on collagen gel contraction by human retinal glial cells.

abstract：OBJECTIVE:To explore the mechanism of cisplatin resistance and its reversion in human ovarian cancer. MATERIALS AND METHODS:A cisplatin resistant cell subline of SKOV3, SKOV3/cp, was established, and a xenograft mice model of human ovarian cancer was established by microencapsulation technology. Various biochemical ch...

journal_title：Chinese medical journal

authors： Liang Z,Bian D

更新日期：1996-05-01 00:00:00

abstract：:A family with Fabry's disease including 2 hemizygotes and 3 heterozygotes is reported. The ocular manifestations include tortuosity of conjunctival vessels, Fabry's deposits underlying the anterior capsule of the lens and the whorl-like corneal dystrophy. Foam cells or mulberry cells in the urinary sediment and varyin...

journal_title：Chinese medical journal

authors： Bao LL,Guo LL,Li SN,Xiao J,Yang JS,Bai LR,Ye PM,Guo ZT,Liu DW

更新日期：1990-02-01 00:00:00

abstract：OBJECTIVE:To determine whether mutation of the coding or junction region of glucokinase gene (GCK) is also the pathogenic cause of the common form of non-insulin-dependent diabetes mellitus (NIDDM) in Chinese. METHODS:Single strand conformation polymorphism (SSCP) analysis was performed after the 12 exons and junction...

journal_title：Chinese medical journal

authors： Xiang K,Wu S,Zheng T,Sun D,Wang Y,Pu L

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND:There is no detailed report about the angiographic leakage of polypoidal choroidal vasculopathy (PCV) lesions on indocyanine green (ICG) angiography. This study aimed to investigate the angiographic leakage of polypoidal lesions in PCV on ICG angiography. METHODS:One hundred and forty-four eyes of 137 patie...

journal_title：Chinese medical journal

authors： Zuo CG,Wen F,Huang SZ,Luo GW,Yan H,Wu WJ,Wu DZ

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Mirizzi syndrome is often difficult to diagnose before surgery, and is often accompanied by extensive adhesions in the cystohepatic (Calot's) triangle and the difficulty of separating tissue can lead to bile duct injury and other intraoperative and postoperative complications. The aim of this study is to inv...

journal_title：Chinese medical journal

authors： Li B,Li X,Zhou WC,He MY,Meng WB,Zhang L,Li YM

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Candidal esophagitis is the primary infection among all digestive tract opportunistic ones in acquired immunodeficiency syndrome (AIDS) cases. X-ray manifestation reports of it are still rare. This study aimed to conduct a retrospective analysis on the X-ray data of 6 AIDS cases complicated with candidal eso...

journal_title：Chinese medical journal

authors： Yang GD,Lu PX,Qin J,Liu ST,Zhan NY

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:Parkinson's disease (PD) is featured with motor disorder and nonmotor manifestations including psychological symptoms, autonomic nervous system dysfunction, and paresthesia, which results in great inconvenience to the patients' life. The apolipoprotein (Apo) superfamily, as a group of potentially modifiable b...

journal_title：Chinese medical journal

authors： Li L,Liu MS,Li GQ,Tang J,Liao Y,Zheng Y,Guo TL,Kang X,Yuan MT

更新日期：2017-11-05 00:00:00

abstract：:This study evaluated the diagnostic value of high resolution CT (HRCT) for atresia of the external auditory meatus (EAM) and isolated middle ear malformation. CT scan of the temporal bone was done in 33 patients with such disorders and 5 patients with otosclerosis etc. were studied in the same way for comparison. Coro...

journal_title：Chinese medical journal

authors： Leng TJ,Gong J,Lan BS

更新日期：1992-06-01 00:00:00

abstract：:From April 1989 to July 1991, 72 patients with residual or recurrent nasopharyngeal carcinoma (NPC) were treated by MSH Ir-192 brachytherapy or combined external radiation therapy. All were proven histologically. 39 patients with residual disease and 6 with recurrent lesion at the primary site were identified after on...

journal_title：Chinese medical journal

authors： Gao L,Xu GZ,Yin WB,Yan JH,Cai WM,Gu XZ

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:Previous studies have indicated that the cognitive deficits in patients with Alzheimer's disease (AD) may be due to topological deteriorations of the brain network. However, whether the selection of a specific frequency band could impact the topological properties is still not clear. Our hypothesis is that t...

journal_title：Chinese medical journal

authors： Qin YY,Li YP,Zhang S,Xiong Y,Guo LY,Yang SQ,Yao YH,Li W,Zhu WZ

更新日期：2015-03-05 00:00:00

abstract：BACKGROUND:Mesenchymal stem or stromal cells (MSCs) derived from the induced pluripotent stem cells (iPSCs) have uniform biological activity, which makes the clinical application of MSCs in bone repair possible. Culturing the iPSC-MSCs onto osteoconductive materials is a promising tissue engineering-based strategy in b...

journal_title：Chinese medical journal

authors： Li JY,Wang TT,Li C,Wang ZF,Li S,Ma L,Zheng LL

更新日期：2020-02-05 00:00:00

abstract：BACKGROUND:For patients with severe endometriosis, the spontaneous pregnancy rates have been reported to be near 0 due to extreme distortion of normal pelvic anatomy. Surgery is one of the treatment options; however, if patients failed to conceive after surgery, in vitro fertilization (IVF) is effective. The objective ...

journal_title：Chinese medical journal

authors： Huang XW,Qiao J,Xia EL,Ma YM,Wang Y

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Renal artery stenosis (RAS) is always associated with abnormalities in renal microvascular perfusion (RMP). However, few imaging methods can simultaneously evaluate the degree of luminal stenosis and RMP. Thus, this study will aim to evaluate the feasibility of using contrast-enhanced ultrasound (CEUS) for a...

journal_title：Chinese medical journal

authors： Ren JH,Ma N,Wang SY,Sun YJ,Zhang YW,Guo FJ,Li YJ,Li TH,Ai H,Zhang WD,Li P,Ma WH

更新日期：2019-01-05 00:00:00

abstract：BACKGROUND:The present study was undertaken to replicate the associations of representative polymorphisms in three genes (complement factor H (CFH), complement factor B (BF) and HtrA serine peptidase 1 (HTRA1)) with exudative age-related macular degeneration (AMD) in a Han Chinese population, and to test if the modifia...

journal_title：Chinese medical journal

authors： Chu J,Zhou CC,Lu N,Zhang X,Dong FT

更新日期：2008-12-20 00:00:00

abstract：BACKGROUND:Studies have reported that low bone mineral density (BMD) is prevalent in human immunodeficiency virus (HIV)-infected patients; however, the factors that contribute to HIV-related BMD changes are yet to be fully understood. Due to the application of dual X-ray absorptiometry (DXA) among a select group of hos...

journal_title：Chinese medical journal

authors： Zeng YQ,Xiao J,Li CL,Wang Y,Zhang L,Pang XL,Wang D,Du J,Zhao HX

更新日期：2020-12-03 00:00:00

abstract：BACKGROUND:Coronary atherosclerotic plaque could go through rapid progression and induce adverse cardiac events. This study aimed to evaluate the impacts of smoking status on clinical outcomes of coronary non-target lesions. METHODS:Consecutive patients with coronary heart disease who underwent two serial coronary ang...

journal_title：Chinese medical journal

authors： Xu HB,Wang J,Chen JL,Guo C,Yuan JS,Duan X,Hu FH,Yang WX,Luo XL,Liu R,Cui JG,Liu SW,Gao XJ,Chun YS,Qiao SB

更新日期：2020-10-05 00:00:00

abstract：:Induced pluripotent stem (iPS) cells are a recent development which has brought a promise of great therapeutic values. The previous technique of somatic cell nuclear transfer (SCNT) has been ineffective in humans. Recent discoveries show that human fibroblasts can be reprogrammed by a transient over expression of a sm...

journal_title：Chinese medical journal

authors： Bhowmik S,Li Y

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Studies have shown that β-blockers can improve cardiac performance in heart failure (HF) by reversing protein kinase A (PKA)-mediated sarcoplasmic reticulum (SR) Ca2+ leak. However, it is being strongly questioned as to whether the PKA-mediated ryanodine receptor (RyR2) hyper-phosphorylation is a critical re...

journal_title：Chinese medical journal

authors： Zhang SJ,Liu ZH,Zou C,Wang L

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy of transcranial Doppler ultrasound (TCD) and digital subtraction angiography (DSA) in identifying the clinical and hemodynamic relationship between intra- and extra-cranial circulation and subclavian steal syndrome. METHODS:Sixteen patients were collected. The intra- and extra-cranial...

journal_title：Chinese medical journal

authors： Huang Y,Gao S,Wang B,Li S

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Immune cells within a tumor microenvironment have shown modulatory effects on tumor angiogenic activity. Renal cell carcinoma (RCC) is a hypervascular tumor that reportedly increases the frequency of regulatory T cells (Tregs) in tumor tissues. This study investigated the correlation between Tregs infiltrati...

journal_title：Chinese medical journal

authors： Ning H,Shao QQ,Ding KJ,Gao DX,Lu QL,Cao QW,Niu ZH,Fu Q,Zhang CH,Qu X,Lü JJ

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:This review aimed to summarize the relationship between intestinal microbiota metabolism and cardiovascular disease (CVD) and to propose a novel CVD therapeutic target. DATA SOURCES:This study was based on data obtained from PubMed and EMBASE up to June 30, 2015. Articles were selected using the following se...

journal_title：Chinese medical journal

authors： Liu TX,Niu HT,Zhang SY

更新日期：2015-10-20 00:00:00

abstract：OBJECTIVE:To investigate the localization of Ca(2+)-ATPase (Ca(2+) pump) in the cochlear and its change after endolymphatic hydrops, and to study the relationship between compound action potential (CAP) threshold and the Ca(2+)-ATPase activety. METHODS:The left endolymphatic sac was ablated to induce endolymphatic hyd...

journal_title：Chinese medical journal

authors： Zhang S,Yang W,Sun J,Zhao C,Zhou N

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:Lumbar spinal stenosis is a common problem that is receiving attention with the advent of novel treatment procedures. Prior positional MRI studies demonstrated lumbar canal diameter changes with flexion and extension. There have not been any studies to examine the amount of spinal canal diameter change relat...

journal_title：Chinese medical journal

authors： Wei F,Wang J,Zou J,Hong SW,Zhang H,He W,Miyazaki M,Lee SH,Alanay A

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:To investigate the occurrence and extent of apoptosis in the course of restenosis. METHODS:The experimental models of vessel narrowness and intima thickness were established in minipigs' iliac arteries by balloon injury and specimens were retrieved on the 1st, 3rd, 6th, 12th and 30th days for dynamic observa...

journal_title：Chinese medical journal

authors： Huang J,Yin H,Leng J,Yao Y,Yao R,Peng T,Li J

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:To determine the relationships of Met416Val and XbaI polymorphism of muscle glycogen synthase (GYS1) gene and Trg64Arg variant of the beta(3)-adrenergic-receptor (beta(3)-AR) gene with type 2 diabetes mellitus (DM) and its intermediate phenotypes in the Chinese population. METHODS:Polymerase chain reaction-o...

journal_title：Chinese medical journal

authors： Wang G,Li Q,Niu T,Chen C,Xu X

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:In steroid-induced osteonecrosis, hypertrophy and hyperplasia of marrow fat cells and lipid deposition of osteocytes can be found in the femoral head. However, the precise reason is not clear yet. The aim of this study was to observe the effect of dexamethasone (Dex) on differentiation of marrow stromal cell...

journal_title：Chinese medical journal

authors： Yin L,Li YB,Wang YS

更新日期：2006-04-05 00:00:00

abstract：OBJECTIVE:To investigate the effects of gypenosides (Gs) on cellular immunocompetence in the gamma-ray-irradiated mice. MATERIALS AND METHODS:Tested mice of ICR strain were treated continuously with Gs for 10 days before or after 4 Gy gamma-irradiation. Body weight and splenic weight of mice were measured. The blastog...

journal_title：Chinese medical journal

authors： Hau DM,Feng Y,Chen WC,Lin IH,Chen KT,Lin SS,Wang MI

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:Survivin is an oncoprotein silenced in normal mature tissues but reactivated in serous ovarian cancer (SOC). Although transcriptional activation is assumed for its overexpression, the long 3'-untranslated region (3'-UTR) in survivin gene, which contains many alternate polyadenylation (APA) sites, implies a p...

journal_title：Chinese medical journal

authors： He XJ,Zhang Q,Ma LP,Li N,Chang XH,Zhang YJ

更新日期：2016-05-20 00:00:00

abstract：:The effect of harringtonine (HA) in various concentrations on HL-60 was evaluated. 0.10 microgram/ml HA showed a strong cell killing effect, and 0.025 microgram/ml HA a weak differentiation induction accompanied by cell growth retardation. Differentiation induction did not occur in 5 other human leukemic cell lines. W...

journal_title：Chinese medical journal

authors： Chen SS,Wang P,Fu JY,Chen LL,Zhao FS,Shan FX

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:Beta(2)-adrenoceptor (beta(2)AR) desensitization is a common problem in clinical practice. beta(2)AR desensitization proceeds by at least such three mechanisms as heterologous desensitization, homologous desensitization and a kind of agonist-induced rapid phosphorylation by a variety of serine/threonine kina...

journal_title：Chinese medical journal

authors： Liu H,Zhou LF,Zhang Q,Qian FH,Yin KS,Huang M,Zhang XL

更新日期：2008-02-20 00:00:00