APE1 Asp148Glu gene polymorphism and bladder cancer risk: a meta-analysis.

abstract：:The aim of the present study was construction of mammary gland specific expression vector for high level of human insulin (hINS) expression in transgenic buffalo for therapeutic use. We have constructed mammary gland specific vector containing human insulin gene and there expression efficiency was checked into in vitr...

journal_title：Molecular biology reports

authors： Kaushik R,Singh KP,Kumari A,Rameshbabu K,Singh MK,Manik RS,Palta P,Singla SK,Chauhan MS

更新日期：2014-09-01 00:00:00

abstract：:Ebselen, an organoselenium compound, mimics glutathione peroxidase activity. It is a multifunctional compound, which catalyzes several essential reactions for the protection of cellular components from oxidative and free radical damage. Based on a number of in vitro and in vivo studies, various mechanisms are proposed...

journal_title：Molecular biology reports

authors： Azad GK,Tomar RS

更新日期：2014-08-01 00:00:00

abstract：:Insect molting is an important developmental process of metamorphosis, which is initiated by molting hormone. The molting process includes the activation of dermal cells, epidermal cells separation, molting fluid secretion, the formation of new epidermis and old epidermis excoriation etc. Polyphenol oxidases (PPOs), d...

journal_title：Molecular biology reports

authors： Wang MX,Lu Y,Cai ZZ,Liang S,Niu YS,Miao YG

更新日期：2013-05-01 00:00:00

abstract：:Selenium compounds have been widely investigated as novel anticancer agents due to high efficacy and selectivity against cancer cells in recent years. This study aimed to research the potential inhibitory effects of seleno-β-lactoglobulin (Se-β-Lg) on HepG2 cells in vitro. MTT results demonstrated that the synthetized...

journal_title：Molecular biology reports

authors： Ji HY,Yu J,Liu AJ

更新日期：2019-10-01 00:00:00

abstract：:HMG proteins were extracted with 5% PCA or 0.35 M NaCl from whole tissue, nuclei or chromatin of the liver of young (19 weeks) and old (118 weeks) male rats. They were resolved on acetic acid-urea polyacrylamide gel. The electrophoretic patterns of the major HMG proteins 1, 2, 14 and 17 of both ages are similar. The i...

journal_title：Molecular biology reports

authors： Thakur MK,Prasad S

更新日期：1991-02-01 00:00:00

abstract：:Rheumatoid arthritis (RA) and ankylosing spondylitis (AS) are autoimmune, inflammatory diseases with substantial genetic contributions. Matrix metalloproteinase (MMP)-2, tumor necrosis factor (TNF)-α and NLR family pyrin domain-containing 1 (NLRP1) play important roles in the immune response. We studied the MMP-2 rs24...

journal_title：Molecular biology reports

authors： Sun R,Huang Y,Zhang H,Liu R

更新日期：2013-11-01 00:00:00

abstract：:'Molecular sandwiches' composed of two aromatic amino acids separated by a hydrophilic one were found on eleven subspecies of human interferon alpha, on murine interferon alpha 2, and human interferon beta 1. In addition, another type of the sandwiches was found on several species of interferon. This confirms and exte...

journal_title：Molecular biology reports

authors： Inglot AD,Popik W,Piasecki E,Czyrski J

更新日期：1986-01-01 00:00:00

abstract：:Mouse DNA and chromatin were melted on hydroxyapatite and the denaturation profiles of ribosomal and satellite DNAs were followed by hybridization with their complementary RNAs. Neither ribosomal nor bulk DNA had significantly different melting profiles in chromatin as compared to DNA. However, most of satellite DNA e...

journal_title：Molecular biology reports

authors： Pashev IG

更新日期：1977-06-01 00:00:00

abstract：:This meta-analysis was performed to assess the relationships between the PON1 Q192R (rs662 T>C) polymorphism and the clinical outcome of antiplatelet treatment after percutaneous coronary intervention (PCI). A range of electronic databases were searched: Web of Science (1945-2013), the Cochrane Library Database (Issue...

journal_title：Molecular biology reports

authors： Li P,Bu SH,Lu XT,Li LX,Xu AJ,Tang YN,Zhang J

更新日期：2014-09-01 00:00:00

abstract：:Development of a rapid and accurate quantification method for the detection of microRNAs (miRNAs) has been desired, in particular, when they are differently expressed in normal and pathological conditions. However, various methods for the quantification of small non-coding RNAs as well as miRNAs have been described. T...

journal_title：Molecular biology reports

authors： Mohammadi-Yeganeh S,Paryan M,Mirab Samiee S,Soleimani M,Arefian E,Azadmanesh K,Mostafavi E,Mahdian R,Karimipoor M

更新日期：2013-05-01 00:00:00

abstract：:There is an increasing body of evidence that a brief exposure to anesthesia induces ischemic tolerance in rat brain (anesthetic preconditioning). However, it is unknown whether preconditioning with sevoflurane, a commonly used volatile anesthetic in current clinical practice, produces a delayed window of neuroprotecti...

journal_title：Molecular biology reports

authors： Ye Z,Huang YM,Wang E,Zuo ZY,Guo QL

更新日期：2012-05-01 00:00:00

abstract：:In our research, signal transducer and activator of transcription 5b (STAT5b) gene was studied as candidate gene associated with body weight and reproductive traits of Jinghai Yellow chicken. Single nucleotide polymorphisms (SNPs) of STAT5b gene were examined in both Jinghai Yellow chicken and three reference chicken ...

journal_title：Molecular biology reports

authors： Zhao XH,Wang JY,Zhang GX,Wei Y,Gu YP,Yu YB

更新日期：2012-04-01 00:00:00

abstract：:A double-stranded RNA-specific nuclease (ds RNase) has been isolated and partially purified from human placenta by DEAE-cellulose and DNA-cellulose column chromatography. Denatured DNA-cellulose retained most of the single-stranded RNA-specific nuclease (ss RNase) activity, whereas the ds RNase came out in the void vo...

journal_title：Molecular biology reports

authors： Kalyanaraman S,Maran A,Shanmugam G

更新日期：1983-08-01 00:00:00

abstract：:Hypertension is a risk factor for the cardiovascular diseases. Although, several drugs are used to treat hypertension, the success of the antihypertensive therapy is limited. Resveratrol decreases blood pressure in animal models of hypertension. This study researched the mechanisms behind the effects of resveratrol on...

journal_title：Molecular biology reports

authors： Han S,Uludag MO,Usanmaz SE,Ayaloglu-Butun F,Akcali KC,Demirel-Yilmaz E

更新日期：2015-01-01 00:00:00

abstract：:Phage display procedure was applied to the N-terminal domain of human topoisomerase I. The consensus sequence identified for clones binding to the N-terminal domain was found in 35 human proteins that are either permanently or temporarily located in the nucleus. They are in majority involved in the DNA repair, transcr...

journal_title：Molecular biology reports

authors： Trzcińska AM,Girstun A,Piekiełko A,Kowalska-Loth B,Staroń K

更新日期：2002-12-01 00:00:00

abstract：:ATP-binding cassette transporter A1 (ABCA1) modulates plasma levels of high density lipoprotein (HDL), a cardiovascular protecting factor. Tree shrew was considered to be an animal protected from atherosclerosis characterized by high proportion of HDL in plasma. The cDNA clones and expression of tree shrew ABCA1 was i...

journal_title：Molecular biology reports

authors： Zeng WW,Zhou B,Liu HR,Sun GT,Chen BS

更新日期：2009-03-01 00:00:00

abstract：:To investigate the effect of ketamine administration on memory consolidation, p-CREB and c-fos expression in hippocampus of infant rats and the possible mechanism. Ninety-six SD rats of 21 days old were divided into seven groups, Y-maze was used to test the ability of learning and memory for minor rats. p-CREB and c-f...

journal_title：Molecular biology reports

authors： Peng S,Zhang Y,Ren B,Zhang J,Wang H

更新日期：2011-04-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) incidence is fast-growing especially in countries highly prevalent with viral hepatitis. Its poor prognosis has driven the research toward the discovery of sensitive markers for early detection. We investigated the usefulness of serum Transforming growth factor-beta1 (TGF-β1), Glypican-3...

journal_title：Molecular biology reports

authors： Ibrahim GH,Mahmoud MA,Aly NM

更新日期：2013-12-01 00:00:00

abstract：:Our previous studies have shown that miR-125b-5p was highly expressed and significantly upregulated during abdominal fat deposition in chickens. However, the role of miR-125b in the regulation of adipogenesis is not clear in chickens. Therefore, we evaluated the effects of miR-125b-5p on preadipocyte proliferation and...

journal_title：Molecular biology reports

authors： Li G,Chen Y,Jin W,Zhai B,Li Y,Sun G,Li H,Kang X,Tian Y

更新日期：2021-01-04 00:00:00

abstract：:Tumor necrosis factor-alpha (TNF-α) and interleukin 1 beta (IL-1β) genetic variants which resulting in TNF-α and IL-1 overproduction may increase susceptibility to autoimmune diseases such as atherosclerosis. We have studied the association of TNF-α G308A and IL-1β (+3953) C/T polymorphism with myocardial infarction i...

journal_title：Molecular biology reports

authors： Zeybek U,Toptas B,Karaali ZE,Kendir M,Cakmakoglu B

更新日期：2011-11-01 00:00:00

abstract：:Interferon gamma (IFN-γ) is an important immunoregulatory cytokine that has a central role against viral and bacterial infections. In this study, the cDNA encoding 141 amino acids of mature IFN-γ from mice splenocytes was cloned in a prokaryotic expression vector pQE 30. Optimization of expression conditions resulted ...

journal_title：Molecular biology reports

authors： Kumar M,Singh M,Singh SB

更新日期：2014-10-01 00:00:00

abstract：:Natural killer cell (NK) is known as a major immune system in body through mediating cell death via several possible pathways, and one of three subpopulations of lymphocytes functioning as scavenger of tumor, virus infected cells etc. Our present results found that the SOD-contained silkworm larvae powder caused an en...

journal_title：Molecular biology reports

authors： Yue WF,Yao ML,Liu JM,Li GL,Li XH,Wu XF,Deng W,Sun HX,Zhou JY,Zhang CX,Miao YG

更新日期：2009-01-01 00:00:00

abstract：:Mucopolysaccharidosis IV A (MPS IV A) is a lysosomal storage disease produced by the deficiency of N-acetylgalactosamine-6-sulfate sulfatase (GALNS) enzyme. Although genotype-phenotype correlations have been reported, these approaches have not enabled to establish a complete genotype-phenotype correlation, and they ha...

journal_title：Molecular biology reports

authors： Olarte-Avellaneda S,Rodríguez-López A,Alméciga-Díaz CJ,Barrera LA

更新日期：2014-11-01 00:00:00

abstract：:The occurrence of PFD is closely related with elasticity, toughness, and functional changes of the connective tissue of the pelvic support tissue. This study aims to evaluate the effect of mechanical stretch on the differentiation of BMSCs with a co-culture with pelvic ligament fibroblasts. BMSCs was isolated and iden...

journal_title：Molecular biology reports

authors： Bing Z,Linlin L,Jianguo Y,Shenshen R,Ruifang R,Xi Z

更新日期：2012-05-01 00:00:00

abstract：:Osteoporosis is a common health problem in Mexico, so it is essential to investigate the status of different gene polymorphisms that could serve as genetic susceptibility markers in the Mexican population. Genes with a role in bone metabolism are excellent candidates for association studies. In this study were determi...

journal_title：Molecular biology reports

authors： Falcón-Ramírez E,Casas-Avila L,Cerda-Flores RM,Castro-Hernández C,Rubio-Lightbourn J,Velázquez-Cruz R,Diez-G P,Peñaloza-Espinosa R,Valdés-Flores M

更新日期：2013-03-01 00:00:00

abstract：:The cell cycle is a complex and strictly controlled process, consisting of different phases. Cell cycle regulation depends on phase-specific transcriptions of cell cycle genes. The alterations of cell cycle genes can predispose normal cells to have a cancerous phenotype. Indeed, several mechanisms underlying the dereg...

journal_title：Molecular biology reports

authors： Caglar HO,Biray Avci C

更新日期：2020-04-01 00:00:00

abstract：:The aim of this study was to explore whether the cytotoxic T lymphocyte antigen-4 (CTLA-4) +49 A/G polymorphism confers susceptibility to rheumatoid arthritis (RA). A meta-analysis was conducted on the associations between CTLA-4 +49 A/G polymorphism and RA using; 1) allele contrast, 2) the recessive model, 3) the dom...

journal_title：Molecular biology reports

authors： Lee YH,Bae SC,Choi SJ,Ji JD,Song GG

更新日期：2012-05-01 00:00:00

abstract：:Using kinetics of approach to steady state labeling, we have found that liver poly(A)+ mRNAs fall into three populations, differing in stability and probably in processing, as reflected in their dissimilar delays in reaching polyribosomes and turnover times. There are mRNA-1 (delay 10 min, half-life 1 hr); mRNA-2(dela...

journal_title：Molecular biology reports

authors： Lubimova EV,Chernovskaja TV,Lerman MI

更新日期：1975-12-01 00:00:00

abstract：:This study was designed to identify the differential expression of the canonical transient receptor potential (TRPC) channels in the left ventricle of spontaneously hypertensive rats (SHR). Echocardiography studies were performed to compare the left ventricular function in SHR vs. Wistar-Kyoto rats (WKY), and the mRNA...

journal_title：Molecular biology reports

authors： Liu FF,Ma ZY,Li DL,Feng JB,Zhang K,Wang R,Zhang W,Li L,Zhang Y

更新日期：2010-07-01 00:00:00

abstract：:Experiments with 5'-azacytidine and hematopoietic growth factor approved for the transformation of human mesenchymal cells into hematopoietic cells have demonstrated that cell fate can be dramatically altered by changing the epigenetic state of cells. Here, we demonstrate that umbilical cord-derived human mesenchymal ...

journal_title：Molecular biology reports

authors： Hu K,Xu C,Ni H,Xu Z,Wang Y,Xu S,Ji K,Xiong J,Liu H

更新日期：2014-07-01 00:00:00