Abstract:
PURPOSE:To evaluate the absolute blood flow rate in a single choroidal vessel using Doppler optical coherence tomography (OCT). METHODS:Three choroidal vessels were selected in the right eye of three normal subjects, and were measured with Doppler OCT at a 1020-nm probe wavelength. The pulsatile change of the blood flow was obtained from synchronized measurement of Doppler OCT and plethysmography. Absolute blood flow rates in choroidal vessels were calculated from Doppler OCT volume data. RESULTS:The cyclic change of the blood flow was quantitatively obtained. Absolute blood flow velocities and blood flow rates at peak systole [mean (SD)] were 46.9 (12.5) mm/s and 5.9 (3.6) μL/min, respectively. The coefficient of variation of three sets of measurements [mean (SD)] was 9.3 (4.9%). CONCLUSIONS:Doppler OCT and plethysmography provided an accurate quantitative assessment of the blood flow in choroidal vessels. This measurement technique could prove valuable to the study of choroidal blood flow in normal and pathologic conditions.
journal_name
Invest Ophthalmol Vis Scijournal_title
Investigative ophthalmology & visual scienceauthors
Miura M,Makita S,Iwasaki T,Yasuno Ydoi
10.1167/iovs.12-10666subject
Has Abstractpub_date
2012-10-01 00:00:00pages
7137-41issue
11eissn
0146-0404issn
1552-5783pii
iovs.12-10666journal_volume
53pub_type
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