Structural and antigenic analysis of Chlamydia pneumoniae.

abstract：:Aspergillus species are saprophytic molds causing life-threatening invasive fungal infections in the immunocompromised host. Innate immune recognition, in particular, the mechanisms of opsonization and complement activation, has been reported to be an integral part of the defense against fungi. We have shown that the ...

journal_title：Infection and immunity

authors： Bidula S,Kenawy H,Ali YM,Sexton D,Schwaeble WJ,Schelenz S

更新日期：2013-05-01 00:00:00

abstract：:Calprotectin, an S100 calcium-binding protein with broad-spectrum antimicrobial activity in vitro, is expressed in neutrophils, monocytes, and gingival keratinocytes. In periodontitis, calprotectin appears upregulated and is detected at higher levels in gingival crevicular fluid and tissue specimens. How calprotectin ...

journal_title：Infection and immunity

authors： Nisapakultorn K,Ross KF,Herzberg MC

更新日期：2001-07-01 00:00:00

abstract：:We have developed an improved scheme for the classification of environmental and clinical isolates of Histoplasma capsulatum that is based on analysis of mitochondrial DNA (mtDNA) and ribosomal DNA (rDNA). Strains were initially divided into mtDNA groups according to restriction digests of whole-cell DNA and Southern ...

journal_title：Infection and immunity

authors： Spitzer ED,Lasker BA,Travis SJ,Kobayashi GS,Medoff G

更新日期：1989-05-01 00:00:00

abstract：:Delayed-type hypersensitivity (DTH) is the standard measure of T-cell responsiveness to infectious organisms. For leprosy, the Mitsuda reaction, a local immune response to cutaneous challenge with Mycobacterium leprae, is considered to represent a measure of DTH against the pathogen. We analyzed the diversity of the T...

journal_title：Infection and immunity

authors： Uyemura K,Ohmen JD,Grisso CL,Sieling PA,Wyzykowski R,Reisinger DM,Rea TH,Modlin RL

更新日期：1992-11-01 00:00:00

abstract：:Shiga toxigenic Escherichia coli (STEC) strains are a diverse group of organisms capable of causing severe gastrointestinal disease in humans. Within the STEC family, eae-positive STEC strains, particularly those belonging to serogroups O157 and O111, appear to have greater virulence for humans. However, in spite of b...

journal_title：Infection and immunity

authors： Paton AW,Paton JC

更新日期：1999-11-01 00:00:00

abstract：:Chlamydia pneumoniae is a human respiratory pathogen. Unlike the other two Chlamydia species, no species-specific antigen has been defined for C. pneumoniae. An immunoreactive clone containing a 0.8-kb fragment was isolated from a C. pneumoniae (AR-39) genomic library by using anti-C. pneumoniae rabbit immune serum. B...

journal_title：Infection and immunity

authors： Perez Melgosa M,Kuo CC,Campbell LA

更新日期：1994-03-01 00:00:00

abstract：:Recombinant major surface antigen (P30), which was produced as a glutathione S-transferase (EC 2.5.1.18) fusion protein of Toxoplasma gondii, was found to be able to activate macrophages to kill T. gondii in vitro. The macrophage activation was due to P30 in the fusion protein, not to glutathione S-transferase. ...

journal_title：Infection and immunity

authors： Makioka A,Kobayashi A

更新日期：1991-08-01 00:00:00

abstract：:Immunoglobulin class-specific antibodies were measured by a solid-phase radioimmunoassay in serum, bronchoalveolar washings (BAW), lung cell lysates, and spleen cell lysates in germfree mice after intranasal (i.n.) and intraperitoneal (i.p.) primary and secondary 10(5), 10(4), and 10(3) mean tissue culture infective d...

journal_title：Infection and immunity

authors： Charlton D,Blandford G

更新日期：1977-09-01 00:00:00

abstract：:A synthetic medium capable of supporting growth of Vibrio parahaemolyticus is described. Growth yields and generation times were comparable to growth in a complex medium, although Kanagawa hemolysin was undetectable in the synthetic medium. Upon the addition of single amino acids to this synthetic medium, only D-trypt...

journal_title：Infection and immunity

authors： Cherwonogrodzky JW,Clark AG

更新日期：1982-07-01 00:00:00

abstract：:The porcine immunoglobulins M (IgM), A (IgA), and G (IgG) were isolated and purified and some of the properties of the porcine milk IgA were examined. Monospecific antisera which were prepared against these immunoglobulins in rabbits were then used to absorb a particular class of immunoglobulin from sow serum, colostr...

journal_title：Infection and immunity

authors： Saif LJ,Bohl EH,Gupta RK

更新日期：1972-10-01 00:00:00

abstract：:Suitability of the rhesus monkey (Macaca mulatta) as an experimental host for evaluation of vaccines against airborne infection with Mycobacterium tuberculosis strain H37Rv was investigated. Nonvaccinated monkeys were exposed to estimated doses of 12, 25, or 49 units of H37Rv in a modified Henderson apparatus, and the...

journal_title：Infection and immunity

authors： Barclay WR,Anacker RL,Brehmer W,Leif W,Ribi E

更新日期：1970-11-01 00:00:00

abstract：:Two enteropathogenic strains of Escherichia coli (EEC) differed from a nonenteropathogenic strain of E. coli (NEEC) in their association with porcine small intestinal epithelium. The EEC characteristically were found along villi from tip to base and contiguous to the brush border. They were not in crypts. In contrast,...

journal_title：Infection and immunity

authors： Bertschinger HU,Moon HW,Whipp SC

更新日期：1972-04-01 00:00:00

abstract：:Neisseria gonorrhoeae is generally considered to be an obligate aerobe; it can, however, grow in the absence of oxygen by anaerobic respiration by using nitrite as a terminal electron acceptor. The outer membrane protein compositions of aerobically and anaerobically grown N. gonorrhoeae strains were compared by one- a...

journal_title：Infection and immunity

authors： Clark VL,Campbell LA,Palermo DA,Evans TM,Klimpel KW

更新日期：1987-06-01 00:00:00

abstract：:We have demonstrated that possession of the gene for thermostable direct hemolysin-related hemolysin (trh) coincides with the presence of the urease gene among clinical Vibrio parahaemolyticus strains and that the location of the two genes are in close proximity on the chromosome. Here, we cloned and sequenced the 15,...

journal_title：Infection and immunity

authors： Park KS,Iida T,Yamaichi Y,Oyagi T,Yamamoto K,Honda T

更新日期：2000-10-01 00:00:00

abstract：:The ability of hemagglutinating and poorly hemagglutinating strains of the gastroduodenal pathogen Helicobacter pylori to bind 125I-radiolabelled laminin was quantitated in a liquid phase assay. Although all strains bound laminin, some hemagglutinating strains were good binders of laminin (maximum of 31% binding), whe...

journal_title：Infection and immunity

authors： Valkonen KH,Wadström T,Moran AP

更新日期：1994-09-01 00:00:00

abstract：:In this study we have investigated the antibody and CD4 T-cell responses to the well-characterized malaria vaccine candidate MSP-1 during the course of a primary Plasmodium chabaudi chabaudi (AS) infection. Specific antibody responses can be detected within the first week of infection, and CD4 T cells can be detected ...

journal_title：Infection and immunity

authors： Quin SJ,Langhorne J

更新日期：2001-04-01 00:00:00

abstract：:We compared the susceptibilities of Chlamydia trachomatis elementary bodies (EBs) to human defensin HNP-2 and porcine protegrin PG-1, cysteine-rich beta-sheet antimicrobial peptides produced by mammalian leukocytes. Although both peptides protected McCoy cell monolayers from infection by chlamydial EBs, protegrins wer...

journal_title：Infection and immunity

authors： Yasin B,Harwig SS,Lehrer RI,Wagar EA

更新日期：1996-03-01 00:00:00

abstract：:The role of the spleen in hepatic amoebiasis in hamsters was studied. In hamsters receiving an intrahepatic inoculation of 10(5) trophozoites of axenic Entamoeba histolytica at 7 or 14 days postsplenectomy, the mean weight of metastatic foci increased significantly when compared with sham-splenectomized or intact cont...

journal_title：Infection and immunity

authors： Ghadirian E,Meerovitch E

更新日期：1981-02-01 00:00:00

abstract：:The purified recombinant V antigen from Yersinia pestis, expressed in Escherichia coli and adsorbed to aluminum hydroxide, an adjuvant approved for human use, was used to immunize outbred Hsd:ND4 mice subcutaneously. Immunization protected mice from lethal bubonic and pneumonic plague caused by CO92, a wild-type F1+ s...

journal_title：Infection and immunity

authors： Anderson GW Jr,Leary SE,Williamson ED,Titball RW,Welkos SL,Worsham PL,Friedlander AM

更新日期：1996-11-01 00:00:00

abstract：:The mechanism of activation of intestinal guanylate cyclase by Escherichia coli heat-stable enterotoxin (STa) has been studied by using isolated rat intestinal epithelial cells and purified brush border membrane (BBM) preparations. Inhibitors of prostaglandin biosynthesis, quinacrine and 5,8,11,14-eicosatetraynoic aci...

journal_title：Infection and immunity

authors： Dreyfus LA,Jaso-Friedmann L,Robertson DC

更新日期：1984-05-01 00:00:00

abstract：:Porphyromonas gingivalis, a gram-negative anaerobic bacterium associated with active lesions of chronic periodontitis, produces several proteinases which are presumably involved in host colonization, perturbation of the immune system, and tissue destruction. The aims of this study were to investigate the degradation o...

journal_title：Infection and immunity

authors： Goulet V,Britigan B,Nakayama K,Grenier D

更新日期：2004-08-01 00:00:00

abstract：:Cytolethal distending toxins (CDT) constitute an emerging heterogeneous family of bacterial toxins whose common biological property is to inhibit the proliferation of cells in culture by blocking their cycle at G2/M phase. In this study, we investigated the molecular mechanisms underlying the block caused by CDT from ...

journal_title：Infection and immunity

authors： Comayras C,Tasca C,Pérès SY,Ducommun B,Oswald E,De Rycke J

更新日期：1997-12-01 00:00:00

abstract：:Streptococcus mutans Ingbritt was grown anaerobically in a chemostat, at a rate (mean generation time, 13 h) similar to that in dental plaque, in a complex medium with excess glucose and at pH values of 6.5, 6.0, and 5.5. The yield of cells was constant at pH 6.5 and 6.0 (2.00 mg/ml) but fell to 1.25 at pH 5.5; Y(gluc...

journal_title：Infection and immunity

authors： Hamilton IR,Ellwood DC

更新日期：1978-02-01 00:00:00

abstract：:The Pseudomonas aeruginosa quorum-sensing systems, las and rhl, control the production of numerous virulence factors. In this study, we have used the burned-mouse model to examine the contribution of quorum-sensing systems to the pathogenesis of P. aeruginosa infections in burn wounds. Different quorum-sensing mutants...

journal_title：Infection and immunity

authors： Rumbaugh KP,Griswold JA,Iglewski BH,Hamood AN

更新日期：1999-11-01 00:00:00

abstract：:Host-driven macrophage apoptosis contributes to innate immunity during bacterial infection. Neisseria meningitidis inhibits apoptosis in a variety of cells, but its impact on macrophage apoptosis is unknown. We demonstrate that N. meningitidis prevents macrophage apoptosis via genes encoding nitric oxide detoxificatio...

journal_title：Infection and immunity

authors： Tunbridge AJ,Stevanin TM,Lee M,Marriott HM,Moir JW,Read RC,Dockrell DH

更新日期：2006-01-01 00:00:00

abstract：:Sendai virus is one of the more prevalent and serious virus infections of rodents. Infection was found in 66% of the mouse, 63% of the rat, 83% of the hamster, and 44% of the guinea pig colonies examined. Twenty-four inbred and outbred strains of mice were tested for their sensitivity to lethal Sendai virus infection....

journal_title：Infection and immunity

authors： Parker JC,Whiteman MD,Richter CB

更新日期：1978-01-01 00:00:00

abstract：:Antibodies to Escherichia coli O and K antigens were raised in rabbits by repeated immunizations with whole, Formalin-killed and, later, liver bacteria. The serum antibody levels were determined with the ammonium sulfate precipitation technique after radioiodinating the antigens. The K antigens had to be conjugated to...

journal_title：Infection and immunity

authors： Kaijser B,Ahlstedt S

更新日期：1977-08-01 00:00:00

abstract：:Cultured mammalian cells extend the time of survival of Treponema pallidum (Nichols strain). Various parameters that have been previously shown to enhance treponemal survival in vitro were examined for influences on the interaction of T. pallidum with cultured cells. With cells derived from normal rabbit testes, the t...

journal_title：Infection and immunity

authors： Fitzgerald TJ,Johnson RC,Sykes JA,Miller JN

更新日期：1977-02-01 00:00:00

abstract：:The objective of these studies was to determine the role of macrophage inflammatory protein 1alpha/CCL3 in pulmonary host defense during Klebsiella pneumoniae infection. Following intratracheal inoculation, 7-day survival of CCL3(-/-) mice was less than 10%, compared to 60% for CCL3(+/+) mice. Survival of CCR5(-/-) mi...

journal_title：Infection and immunity

authors： Lindell DM,Standiford TJ,Mancuso P,Leshen ZJ,Huffnagle GB

更新日期：2001-10-01 00:00:00

abstract：:Immunocompromised patients are more susceptible to recurrent nontyphoidal Salmonella (NTS) bacteremia. A key manifestation of HIV infection is the loss of CD4 T cells, which are crucial for immunity to Salmonella infection. We characterized the consequences of CD4 T cell depletion in mice where virulent Salmonella est...

journal_title：Infection and immunity

authors： Loomis WP,Delaney MA,Johnson ML,Cookson BT

更新日期：2020-12-15 00:00:00